Literature for inhibitor I35.002: timp-2
(Topics flags: S Structure, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, L Localization, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)
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Cavalcante,G.L., Bonifacio,L.P., Sanches-Lopes,J.M., Puga,F.G., de Carvalho,F.S., Bellissimo-Rodrigues,F. and Tanus-Santos,J.E.
Matrix metalloproteinases are associated with severity of disease among COVID-19 patients: A possible pharmacological target
Basic Clin Pharmacol Toxicol134, 727-736. PubMed Europe PubMed DOI L -
Delrue,C. and Speeckaert,M.M.
Tissue Inhibitor of Metalloproteinases-2 (TIMP-2) as a Prognostic Biomarker in Acute Kidney Injury: A Narrative Review
Diagnostics (Basel)14, PubMed Europe PubMed DOI V -
Gowtham,P., Girigoswami,K., Thirumalai,A., Harini,K., Pallavi,P. and Girigoswami,A.
Association of TIMP2 418 G/C and MMP Gene Polymorphism with Risk of Urinary Cancers: Systematic Review and Meta-analysis
Genet Test Mol Biomarkers28, 83-90. PubMed Europe PubMed DOI -
Leng,J., Li,L., Tu,H., Luo,Y., Cao,Z., Zhou,K., Rizvi,S.M.M., Tie,H. and Jiang,Y.
Mechanism and clinical role of TIMP-2 and IGFBP-7 in cardiac surgery-associated acute kidney injury: A review
Medicine (Baltimore)103, e38124-e38124. PubMed Europe PubMed DOI -
Rotenberg,N., Feldman,M., Shirian,J., Hockla,A., Radisky,E.S. and Shifman,J.M.
Engineered TIMP2 with narrow MMP-9 specificity is an effective inhibitor of invasion and proliferation of triple negative breast cancer cells
J Biol Chem107867-107867. PubMed Europe PubMed DOI -
Abouhadid,M.A., Gawad,T.A.A., Gebaly,H.H.E., Abdallah,A.A., Refay,A.S.E., Helmy,N.M. and Allam,A.M.
Urinary tissue inhibitor of metalloproteinase-2 as an early predictor for acute kidney injury in critically ill children
Int J Health Sci (Qassim)17, 22-28. PubMed Europe PubMed -
Barreto,J.N., Barreto,E.F., Mara,K.C., Rule,A.D., Lieske,J.C., Giesen,C.D., Thompson,C.A., Leung,N., Witzig,T.E. and Kashani,K.B.
Tissue Inhibitor Metalloproteinase-2 and Insulin-Like Growth Factor Binding Protein-7 Kinetics Following Exposure to High-Dose Methotrexate
Kidney3604, 673-679. PubMed Europe PubMed DOI -
Bonadio,A., Wenig,B.L., Hockla,A., Radisky,E.S. and Shifman,J.M.
Designed Loop Extension Followed by Combinatorial Screening Confers High Specificity to a Broad Matrix MetalloproteinaseInhibitor
J Mol Biol435, 168095-168095. PubMed Europe PubMed DOI -
Coates-Park,S., Lazaroff,C., Gurung,S., Rich,J., Colladay,A., O'Neill,M., Butler,G.S., Overall,C.M., Stetler-Stevenson,W.G. and Peeney,D.
Tissue inhibitors of metalloproteinases are proteolytic targets of matrix metalloproteinase 9
Matrix Biol123, 59-70. PubMed Europe PubMed DOI -
Da Silva,J., Freitas,J.R., do Carmo,E.R. and Gomes,J.R.
MT1-MMP and TIMP-2 are first expressed in the colon glands after a single dose of azoxymethane (AOM)
Anat Rec (Hoboken) PubMed Europe PubMed DOI -
Hayun,H., Coban,M., Bhagat,A.K., Ozer,E., Alfonta,L., Caulfield,T.R., Radisky,E.S. and Papo,N.
Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14
Res Sq PubMed Europe PubMed DOI -
Hayun,H., Coban,M., Bhagat,A.K., Ozer,E., Alfonta,L., Caulfield,T.R., Radisky,E.S. and Papo,N.
Utilizing genetic code expansion to modify N-TIMP2 specificity towards MMP-2, MMP-9, and MMP-14
Sci Rep13, 5186-5186. PubMed Europe PubMed DOI -
Sangwan,P., Quasimi,H., Sharma,J.G., Habib,M.A. and Alam,M.I.
Role of Oxidative Stress and Genetic Polymorphism of Matrix Metalloproteinase-2 and Tissue Inhibitor of Metalloproteinase-2 in COPD
Chronic Obstr Pulm Dis PubMed Europe PubMed DOI V -
Stetler-Stevenson,W.G.
The Continuing Saga of Tissue Inhibitor of Metalloproteinase 2: Emerging Roles in Tissue Homeostasis and Cancer Progression
Am J Pathol193, 1336-1352. PubMed Europe PubMed DOI V -
Li,N., Geng,F., Liang,S.M. and Qin,X.
USP7 inhibits TIMP2 by up-regulating the expression of EZH2 to activate the NF-kappaB/PD-L1 axis to promote the development of cervical cancer
Cell Signal96, 110351-110351. PubMed Europe PubMed DOI -
Peeney,D., Liu,Y., Lazaroff,C., Gurung,S. and Stetler-Stevenson,W.G.
Unravelling the distinct biological functions and potential therapeutic applications of TIMP2 in cancer
Carcinogenesis43, 405-418. PubMed Europe PubMed DOI V -
Dusanovic Pjevic,M., Jekic,B., Beslac Bumbasirevic,L., Vojvodic,L., Damnjanovic,T., Grk,M., Maksimovic,N., Pesic,M., Gulic,M., Trickovic,J. and Kacar,K.
TT genotype of the MMP-9-1562C/T polymorphism may be a risk factor for thrombolytic therapy-induced hemorrhagic complications after acute ischemic stroke
Pharmacotherapy PubMed Europe PubMed DOI -
Esmeijer,K., Schoe,A., Ruhaak,L.R., Hoogeveen,E.K., Soonawala,D., Romijn,F.P.H.T., Shirzada,M.R., van Dissel,J.T., Cobbaert,C.M. and de Fijter,J.W.
The predictive value of TIMP-2 and IGFBP7 for kidney failure and 30-day mortality after elective cardiac surgery
Sci Rep11, 1071-1071. PubMed Europe PubMed DOI -
Nakagawa,M., Shirasugi,M., Yamamoto,T., Nakaya,T. and Kanamura,N.
Long-term exposure to butyric acid induces excessive production of matrix metalloproteases in human gingival fibroblasts
Arch Oral Biol123, 105035-105035. PubMed Europe PubMed DOI L -
Nissi,R., Santala,M. and Talvensaari-Mattila,A.
The serum levels of circulating matrix metalloproteinase MMP-9, MMP-2/TIMP-2 complex and TIMP-1 do not change significantly during normal pregnancy: a pilot study
BMC Res Notes14, 31-31. PubMed Europe PubMed DOI -
Sakyi,S.A., Ephraim,R.K.D., Adoba,P., Amoani,B., Buckman,T., Mantey,R. and Eghan,B.A.
Tissue inhibitor metalloproteinase 2 (TIMP-2) and insulin-like growth factor binding protein 7 (IGFBP7) best predicts the development of acute kidney injury
Heliyon7, e07960-e07960. PubMed Europe PubMed DOI -
Azevedo Martins,J.M., Rabelo-Santos,S.H., do Amaral Westin,M.C. and Zeferino,L.C.
Tumoral and stromal expression of MMP-2, MMP-9, MMP-14, TIMP-1, TIMP-2, and VEGF-A in cervical cancer patient survival: a competing risk analysis
BMC Cancer20, 660-660. PubMed Europe PubMed DOI -
Carreca,A.P., Pravata,V.M., Markham,M., Bonelli,S., Murphy,G., Nagase,H., Troeberg,L. and Scilabra,S.D.
TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1
Sci Rep10, 12067-12067. PubMed Europe PubMed DOI -
Drishya,G., Nambiar,J., Shaji,S.K., Vanuopadath,M., Achuthan,A., Kumar,A., Alias,A., Sherif,A., Joseph,C., Divya,P., Kumar,D.S., Bose,C., Nair,S.V., Sudarslal,S., Kumar,G.B., Lakshmi,S. and Nair,B.G.
RECK and TIMP-2 mediate inhibition of MMP-2 and MMP-9 by Annona muricata
J Biosci45, PubMed Europe PubMed -
Han,Z.L., Wang,H.Q., Zhang,T.S., He,Y.X. and Zhou,H.
Up-regulation of exosomal miR-106a may play a significant role in abdominal aortic aneurysm by inducing vascular smooth muscle cell apoptosis and targeting TIMP-2, an inhibitor of metallopeptidases that suppresses extracellular matrix degradation
Eur Rev Med Pharmacol Sci24, 8087-8095. PubMed Europe PubMed DOI -
Ji,J.J., Qian,L.L., Zhu,Y., Wu,Y.P., Guo,J.Q., Ma,G.S. and Yao,Y.Y.
Serpina3c protects against high-fat diet-induced pancreatic dysfunction through the JNK-related pathway
Cell Signal75, 109745-109745. PubMed Europe PubMed DOI -
Kaczorowska,A., Miekus,N., Stefanowicz,J. and Adamkiewicz-Drozynska,E.
Selected Matrix Metalloproteinases (MMP-2, MMP-7) and Their Inhibitor (TIMP-2) in Adult and Pediatric Cancer
Diagnostics (Basel)10, PubMed Europe PubMed DOI V -
Ke,X., Zhou,Q., Li,B., Shao,X., Hong,G., Zou,H. and Ling,Y.
Tissue Inhibitor of Matrix Metalloproteinase 2-Loaded Polylactic Acid-Polyethylene Glycol Nanoparticles Directly Regulates Renal Tubular Epithelial Cell Proliferation via Protein Tyrosine Kinase KIT
J Nanosci Nanotechnol20, 7425-7432. PubMed Europe PubMed DOI -
Vira,H.J., Pradhan,V.D., Umare,V.D., Chaudhary,A.K., Rajadhyksha,A.G., Nadkar,M.Y., Ghosh,K. and Nadkarni,A.H.
Expression of the matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors TIMP-1 and TIMP-2 in systemic lupus erythematosus patients
Neth J Med78, 261-268. PubMed Europe PubMed -
Voitiv,Y., Usenko,O., Dosenko,V., Dyadyk,O. and Dzhemiliev,A.
ANALYSIS OF POLYMORPHISM OF MATRIX METALLOPROTEINASE-2 (C-1306
Georgian Med News7-12. PubMed Europe PubMed -
Wang,H., Huang,L., Wu,L., Lan,J., Feng,X., Li,P. and Peng,Y.
The MMP-2/TIMP-2 system in Alzheimer disease
CNS Neurol Disord Drug Targets19, 402-416. PubMed Europe PubMed DOI V -
Xue,A., Feng,G., Zhu,C. and Fan,S.
[Prokaryotic expression, purification and characterization of tissue inhibitor of metalloproteinase-2]
Sheng Wu Gong Cheng Xue Bao36, 2868-2876. PubMed Europe PubMed DOI L -
Yang,B., Zhang,D., Qian,J. and Cheng,Y.
Chelerythrine suppresses proliferation and metastasis of human prostate cancer cells via modulating MMP/TIMP/NF-kappaB system
Mol Cell Biochem474, 199-208. PubMed Europe PubMed DOI -
Zhang,Y., Liu,H., Chen,Z., Yu,M., Li,J., Dong,H., Li,N., Ding,X., Ge,Y., Liu,C., Ma,T. and Gui,B.
TLR4-mediated hippocampal MMP/TIMP imbalance contributes to the aggravation of perioperative neurocognitive disorder in db/db mice
Neurochem Int140, 104818-104818. PubMed Europe PubMed DOI -
Zhong,C., Cao,M.J., Shu,M., Sun,L.C., Yang,H.H. and Wu,G.P.
Tissue inhibitor of metalloproteinase-2 (TIMP-2) from red seabream (Pagrus major): molecular cloning and biochemical characterization of highly expressed recombinant protein
Fish Shellfish Immunol95, 556-563. PubMed Europe PubMed DOI -
Arkadash,V., Radisky,E.S. and Papo,N.
Combinatorial engineering of N-TIMP2 variants that selectively inhibit MMP9 and MMP14 function in the cell
Oncotarget9, 32036-32053. PubMed Europe PubMed DOI -
Shirian,J., Arkadash,V., Cohen,I., Sapir,T., Radisky,E.S., Papo,N. and Shifman,J.M.
Converting a broad matrix metalloproteinase family inhibitor into a specific inhibitor of MMP-9 and MMP-14
FEBS Lett592, 1122-1134. PubMed Europe PubMed DOI -
Arkadash,V., Yosef,G., Shirian,J., Cohen,I., Horev,Y., Grossman,M., Sagi,I., Radisky,E.S., Shifman,J.M. and Papo,N.
Development of high affinity and high specificity inhibitors of matrix metalloproteinase 14 through computational design and directed evolution
J Biol Chem292, 3481-3495. PubMed Europe PubMed DOI -
Jiang,B., Zhang,Y., Liu,J., Tsigkou,A., Rapti,M. and Lee,M.H.
Ensnaring membrane type 1-matrix metalloproteinase (MT1-MMP) with tissue inhibitor of metalloproteinase (TIMP)-2 using the haemopexin domain of the protease as a carrier: a targeted approach in cancer inhibition
Oncotarget8, 22685-22699. PubMed Europe PubMed DOI -
Xu,P., Guo,W., Jin,T., Wang,J., Fan,D., Hao,Z., Jing,S., Han,C., Du,J., Jiang,D., Wen,S. and Wang,J.
TIMP-2 SNPs rs7342880 and rs4789936 are linked to risk of knee osteoarthritis in the Chinese Han Population
Oncotarget8, 1166-1176. PubMed Europe PubMed DOI M -
Guo,C., Tsigkou,A. and Lee,M.H.
ADAMTS13 and 15 are not regulated by the full length and N-terminal domain forms of TIMP-1, -2, -3 and -4
Biomed Rep4, 73-78. PubMed Europe PubMed DOI I -
Koppisetti,R.K., Fulcher,Y.G., Jurkevich,A., Prior,S.H., Xu,J., Lenoir,M., Overduin,M. and Van Doren,S.R.
Ambidextrous binding of cell and membrane bilayers by soluble matrix metalloproteinase-12
Nat Commun5, 5552-5552. PubMed Europe PubMed DOI -
Sharabi,O., Shirian,J., Grossman,M., Lebendiker,M., Sagi,I. and Shifman,J.
Affinity- and specificity-enhancing mutations are frequent in multispecific interactions between TIMP2 and MMPs
PLoS ONE9, e93712-e93712. PubMed Europe PubMed DOI -
Stetler-Stevenson,W.G. and Gavil,N.V.
Normalization of the tumor microenvironment: evidence for tissue inhibitor of metalloproteinase-2 as a cancer therapeutic
Connect Tissue Res55, 13-19. PubMed Europe PubMed DOI U -
Ukaji,T., Sasazawa,Y., Umezawa,K. and Simizu,S.
Involvement of conserved tryptophan residues for secretion of TIMP-2
Oncol Lett7, 631-634. PubMed Europe PubMed DOI -
Givvimani,S., Kundu,S., Narayanan,N., Armaghan,F., Qipshidze,N., Pushpakumar,S., Vacek,T.P. and Tyagi,S.C.
TIMP-2 mutant decreases MMP-2 activity and augments pressure overload induced LV dysfunction and heart failure
Arch Physiol Biochem119, 65-74. PubMed Europe PubMed DOI K -
Higashi,S., Hirose,T., Takeuchi,T. and Miyazaki,K.
Molecular design of a highly selective and strong protein inhibitor against matrix metalloproteinase-2 (MMP-2)
J Biol Chem288, 9066-9076. PubMed Europe PubMed DOI -
Pushpakumar,S., Kundu,S., Pryor,T., Givvimani,S., Lederer,E., Tyagi,S.C. and Sen,U.
Angiotensin-II induced hypertension and renovascular remodelling in tissue inhibitor of metalloproteinase 2 knockout mice
J Hypertens31, 2270-2281. PubMed Europe PubMed DOI K -
Takahashi,T., Fujimori,C., Hagiwara,A. and Ogiwara,K.
Recent advances in the understanding of teleost medaka ovulation: the roles of proteases and prostaglandins
Zoolog Sci30, 239-247. PubMed Europe PubMed DOI -
Batra,J., Robinson,J., Soares,A.S., Fields,A.P., Radisky,D.C. and Radisky,E.S.
Matrix metalloproteinase-10 (MMP-10) interaction with tissue inhibitors of metalloproteinases TIMP-1 and TIMP-2: binding studies and crystal structure
J Biol Chem287, 15935-15946. PubMed Europe PubMed DOI S -
Fu,L., Sun,G., Fiorentino,M. and Shi,Y.B.
Characterization of Xenopus tissue inhibitor of metalloproteinases-2: a role in regulating matrix metalloproteinase activity during development
PLoS ONE7, e36707-e36707. PubMed Europe PubMed DOI -
Jiang,J., Qian,B., Mao,S., Zhao,Q., Qiu,X., Liu,Z. and Qiu,Y.
A promoter polymorphism of tissue inhibitor of metalloproteinase-2 gene is associated with severity of thoracic adolescent idiopathic scoliosis
Spine (Phila Pa 1976)37, 41-47. PubMed Europe PubMed DOI M -
Nieuwesteeg,M.A., Walsh,L.A., Fox,M.A. and Damjanovski,S.
Domain specific overexpression of TIMP-2 and TIMP-3 reveals MMP-independent functions of TIMPs during Xenopus laevis development
Biochem Cell Biol90, 585-595. PubMed Europe PubMed DOI -
Bahudhanapati,H., Zhang,Y., Sidhu,S.S. and Brew,K.
Phage display of tissue inhibitor of metalloproteinases-2 (TIMP-2): Identification of selective inhibitors of collagenase-1 (metalloproteinase 1 (MMP-1))
J Biol Chem286, 31761-31770. PubMed Europe PubMed DOI -
Ramani,R., Nilles,K., Gibson,G., Burkhead,B., Mathier,M., McNamara,D. and McTiernan,C.F.
Tissue inhibitor of metalloproteinase-2 gene delivery ameliorates postinfarction cardiac remodeling
Clin Transl Sci4, 24-31. PubMed Europe PubMed DOI U -
Xu,X., Mikhailova,M., Chen,Z., Pal,S., Robichaud,T.K., Lafer,E.M., Baber,S. and Steffensen,B.
Peptide from the C-terminal domain of tissue inhibitor of matrix metalloproteinases-2 (TIMP-2) inhibits membrane activation of matrix metalloproteinase-2 (MMP-2)
Matrix Biol30, 404-412. PubMed Europe PubMed DOI -
Xu,X.Y., Shen,Y.B., Yang,X.M. and Li,J.L.
Cloning and characterization of TIMP-2b gene in grass carp
Comp Biochem Physiol B Biochem Mol Biol159, 115-121. PubMed Europe PubMed DOI -
Kveiborg,M., Jacobsen,J., Lee,M.H., Nagase,H., Wewer,U.M. and Murphy,G.
Selective inhibition of ADAM12 catalytic activity through engineering of tissue inhibitor of metalloproteinase 2 (TIMP-2)
Biochem J430, 79-86. PubMed Europe PubMed DOI -
Sato,H. and Takino,T.
Coordinate action of membrane-type matrix metalloproteinase-1 (MT1-MMP) and MMP-2 enhances pericellular proteolysis and invasion
Cancer Sci101, 843-847. PubMed Europe PubMed DOI V -
Williamson,R.A.
Refolding of TIMP-2 from Escherichia coli Inclusion Bodies
Methods Mol Biol622, 111-121. PubMed Europe PubMed DOI E -
Ledgard,A.M., Lee,R.S. and Peterson,A.J.
Bovine endometrial legumain and TIMP-2 regulation in response to presence of a conceptus
Mol Reprod Dev76, 65-74. PubMed Europe PubMed DOI -
McNally,L.R., Rosenthal,E.L., Zhang,W. and Buchsbaum,D.J.
Therapy of head and neck squamous cell carcinoma with replicative adenovirus expressing tissue inhibitor of metalloproteinase-2 and chemoradiation
Cancer Gene Ther16, 246-255. PubMed Europe PubMed DOI U -
Reuter,B., Bugert,P., Stroick,M., Bukow,S., Griebe,M., Hennerici,M.G. and Fatar,M.
TIMP-2 gene polymorphism is associated with intracerebral hemorrhage
Cerebrovasc Dis28, 558-563. PubMed Europe PubMed DOI M -
D'Alessio,S., Ferrari,G., Cinnante,K., Scheerer,W., Galloway,A.C., Roses,D.F., Rozanov,D.V., Remacle,A.G., Oh,E.S., Shiryaev,S.A., Strongin,A.Y., Pintucci,G. and Mignatti,P.
Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism
J Biol Chem283, 87-99. PubMed Europe PubMed DOI -
Deng,X., He,G., Levine,A., Cao,Y. and Mullins,C.
Adenovirus-mediated expression of TIMP-1 and TIMP-2 in bone inhibits osteolytic degradation by human prostate cancer
Int J Cancer122, 209-218. PubMed Europe PubMed DOI U -
Simeone,A.M., McMurtry,V., Nieves-Alicea,R., Saavedra,J.E., Keefer,L.K., Johnson,M.M. and Tari,A.M.
TIMP-2 mediates the anti-invasive effects of the nitric oxide-releasing prodrug JS-K in breast cancer cells
Breast Cancer Res10, R44-R44. PubMed Europe PubMed DOI -
Zhao,X., Li,H., Ji,W., Shi,X. and Dong,J.
Construction of an adenovirus vector carrying the human tissue inhibitor of metalloproteinase 2 gene
Biosci Trends2, 245-249. PubMed Europe PubMed U -
Maskos,K., Lang,R., Tschesche,H. and Bode,W.
Flexibility and variability of TIMP binding: X-ray structure of the complex between collagenase-3/MMP-13 and TIMP-2
J Mol Biol366, 1222-1231. PubMed Europe PubMed DOI S -
Yan,X., Zhao,H., Zhang,W., Xue,C. and Liu,Z.
Cloning and expressing a recombinant human tissue inhibitor of metalloproteinase-2 (TIMP-2) in methylotrophic yeast Pichia pastoris and its characterizations
Front Biol China2, 170-175. DOI E -
[YEAR:7-10-2006]Jaworski,D.M., Soloway,P., Caterina,J. and Falls,W.A.
Tissue inhibitor of metalloproteinase-2(TIMP-2)-deficient mice display motor deficits
J Neurobiol66, 82-94. PubMed Europe PubMed DOI K -
[YEAR:11-9-2006]Lluri,G., Langlois,G.D., McClellan,B., Soloway,P.D. and Jaworski,D.M.
Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates neuromuscular junction development via a beta1 integrin-mediated mechanism
J Neurobiol66, 1365-1377. PubMed Europe PubMed DOI -
[YEAR:1-9-2006]Pinto,A.F., Terra,R.M., Guimaraes,J.A., Kashiwagi,M., Nagase,H., Serrano,S.M. and Fox,J.W.
Structural features of the reprolysin atrolysin C and tissue inhibitors of metalloproteinases (TIMPs) interaction
Biochem Biophys Res Commun347, 641-648. PubMed Europe PubMed DOI -
[YEAR:15-6-2006]Rapti,M., Knauper,V., Murphy,G. and Williamson,R.A.
Characterization of the AB loop region of TIMP-2. Involvement in pro-MMP-2 activation
J Biol Chem281, 23386-23394. PubMed Europe PubMed DOI -
[YEAR:23-6-2005]Jaworski,D.M., Boone,J., Caterina,J., Soloway,P. and Falls,W.A.
Prepulse inhibition and fear-potentiated startle are altered in tissue inhibitor of metalloproteinase-2 (TIMP-2) knockout mice
Brain Res1051, 81-89. PubMed Europe PubMed DOI K -
[YEAR:15-11-2005]Lee,Y.K., So,I.S., Lee,S.C., Lee,J.H., Lee,C.W., Kim,W.M., Park,M.K., Lee,S.T., Park,D.Y., Shin,D.Y., Park,C.U. and Kim,Y.S.
Suppression of distant pulmonary metastasis of MDA-MB 435 human breast carcinoma established in mammary fat pads of nude mice by retroviral-mediated TIMP-2 gene transfer
J Gene Med7, 145-157. PubMed Europe PubMed DOI -
Miyoshi,H., Kanekura,T., Aoki,T. and Kanzaki,T.
Beneficial effects of tissue inhibitor of metalloproteinases-2 (TIMP-2) on chronic dermatitis
J Dermatol32, 346-353. PubMed Europe PubMed -
Stetler-Stevenson,W.G. and Seo,D.W.
TIMP-2: an endogenous inhibitor of angiogenesis
Trends Mol Med11, 97-103. PubMed Europe PubMed DOI -
[YEAR:12-8-2004]Lee,M.H., Rapti,M. and Murphy,G.
Delineating the molecular basis of the inactivity of tissue inhibitor of metalloproteinase-2 against tumor necrosis factor-alpha-converting enzyme
J Biol Chem279, 45121-45129. PubMed Europe PubMed DOI -
Lodemel,J.B., Egge-Jacobsen,W. and Olsen,R.L.
Detection of TIMP-2-like protein in Atlantic cod (Gadus morhua) muscle using two-dimensional real-time reverse zymography
Comp Biochem Physiol B Biochem Mol Biol139, 253-259. PubMed Europe PubMed DOI -
[YEAR:16-12-2004]Zhao,H., Bernardo,M.M., Osenkowski,P., Sohail,A., Pei,D., Nagase,H., Kashiwagi,M., Soloway,P.D., DeClerck,Y.A. and Fridman,R.
Differential inhibition of membrane type 3 (MT3)-matrix metalloproteinase (MMP) and MT1-MMP by tissue inhibitor of metalloproteinase (TIMP)-2 and TIMP-3 rgulates pro-MMP-2 activation
J Biol Chem279, 8592-8601. PubMed Europe PubMed DOI I -
[YEAR:1-10-2003]Kubota,S., Kinoshita,M., Uji,S., Yokoyama,Y., Yamamoto,E., Hirono,I., Aoki,T., Sakaguchi,M., Morioka,K., Itoh,Y. and Toyohara,H.
Occurrence of two distinct types of tissue inhibitor of metalloproteinases-2 in teleost fish
Biochim Biophys Acta1629, 102-108. PubMed Europe PubMed DOI -
[YEAR:23-10-2003]Lafleur,M.A., Tester,A.M. and Thompson,E.W.
Selective involvement of TIMP-2 in the second activational cleavage of pro-MMP-2: refinement of the pro-MMP-2 activation mechanism
FEBS Lett553, 457-463. PubMed Europe PubMed DOI -
[YEAR:15-6-2003]Worley,J.R., Thompkins,P.B., Lee,M.H., Hutton,M., Soloway,P., Edwards,D.R., Murphy,G. and Knauper,V.
Sequence motifs of tissue inhibitor of metalloproteinases 2 (TIMP-2) determining progelatinase A (proMMP-2) binding and activation by membrane-type metalloproteinase 1 (MT1-MMP)
Biochem J372, 799-809. PubMed Europe PubMed DOI -
Zhang,J., Bai,S., Tanase,C., Nagase,H. and Sarras,M.P., Jr.
The expression of tissue inhibitor of metalloproteinase 2 (TIMP-2) is required for normal development of zebrafish embryos
Dev Genes Evol213, 382-389. PubMed Europe PubMed DOI -
[YEAR:28-5-2002]Morgunova,E., Tuuttila,A., Bergmann,U. and Tryggvason,K.
Structural insight into the complex formation of latent matrix metalloproteinase 2 with tissue inhibitor of metalloproteinase 2
Proc Natl Acad Sci U S A99, 7414-7419. PubMed Europe PubMed DOI S -
[YEAR:13-4-2001]Hashimoto,G., Aoki,T., Nakamura,H., Tanzawa,K. and Okada,Y.
Inhibition of ADAMTS4 (aggrecanase-1) by tissue inhibitors of metalloproteinases (TIMP-1, 2, 3 and 4)
FEBS Lett494, 192-195. PubMed Europe PubMed DOI -
[YEAR:31-8-2001]Williamson,R.A., Hutton,M., Vogt,G., Rapti,M., Knauper,V., Carr,M.D. and Murphy,G.
Tyrosine 36 plays a critical role in the interaction of the AB loop of tissue inhibitor of metalloproteinases-2 with matrix metalloproteinase-14
J Biol Chem276, 32966-32970. PubMed Europe PubMed DOI -
[YEAR:25-8-2000]Caterina,J.J., Yamada,S., Caterina,N.C., Longenecker,G., Holmback,K., Shi,J., Yermovsky,A.E., Engler,J.A. and Birkedal-Hansen,H.
Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2 (Timp-2) gene alters proMMP-2 activation
J Biol Chem275, 26416-26422. PubMed Europe PubMed DOI -
[YEAR:29-12-2000]Toth,M., Bernardo,M.M., Gervasi,D.C., Soloway,P.D., Wang,Z., Bigg,H.F., Overall,C.M., DeClerck,Y.A., Tschesche,H., Cher,M.L., Brown,S., Mobashery,S. and Fridman,R.
Tissue inhibitor of metalloproteinase (TIMP)-2 acts synergistically with synthetic matrix metalloproteinase (MMP) inhibitors but not with TIMP-4 to enhance the (Membrane type 1)-MMP-dependent activation of pro-MMP-2
J Biol Chem275, 41415-41423. PubMed Europe PubMed DOI -
[YEAR:16-7-1999]Butler,G.S., Hutton,M., Wattam,B.A., Williamson,R.A., Knauper,V., Willenbrock,F. and Murphy,G.
The specificity of TIMP-2 for matrix metalloproteinases can be modified by single amino acid mutations
J Biol Chem274, 20391-20396. PubMed Europe PubMed DOI -
[YEAR:12-2-1999]Overall,C.M., King,A.E., Sam,D.K., Ong,A.D., Lau,T.T., Wallon,U.M., DeClerck,Y.A. and Atherstone,J.
Identification of the tissue inhibitor of metalloproteinases-2 (TIMP-2) binding site on the hemopexin carboxyl domain of human gelatinase A by site-directed mutagenesis. The hierarchical role in binding TIMP-2 of the unique cationic clusters of hemopexin modules III and IV
J Biol Chem274, 4421-4429. PubMed Europe PubMed DOI -
[YEAR:9-1-1998]Butler,G.S., Butler,M.J., Atkinson,S.J., Will,H., Tamura,T., Schade van Westrum,S., Crabbe,T., Clements,J., d'Ortho,M.P. and Murphy,G.
The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study
J Biol Chem273, 871-880. PubMed Europe PubMed DOI -
[YEAR:15-7-1998]Farina,A.R., Tacconelli,A., Teti,A., Gulino,A. and Mackay,A.R.
Tissue inhibitor of metalloproteinase-2 protection of matrix metalloproteinase-2 from degradation by plasmin is reversed by divalent cation chelator EDTA and the bisphosphonate alendronate
Cancer Res58, 2957-2960. PubMed Europe PubMed -
[YEAR:1-9-1998]Fernandez-Catalan,C., Bode,W., Huber,R., Turk,D., Calvete,J.J., Lichte,A., Tschesche,H. and Maskos,K.
Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor
EMBO J17, 5238-5248. PubMed Europe PubMed DOI S -
[YEAR:14-7-1998]Hutton,M., Willenbrock,F., Brocklehurst,K. and Murphy,G.
Kinetic analysis of the mechanism of interaction of full-length TIMP-2 and gelatinase A: Evidence for the existence of a low-affinity intermediate
Biochemistry37, 10094-10098. PubMed Europe PubMed DOI -
[YEAR:18-9-1998]Itoh,Y., Ito,A., Iwata,K., Tanzawa,K., Mori,Y. and Nagase,H.
Plasma membrane-bound tissue inhibitor of metalloproteinases (TIMP)-2 specifically inhibits matrix metalloproteinase 2 (gelatinase A) activated on the cell surface
J Biol Chem273, 24360-24367. PubMed Europe PubMed DOI -
Muskett,F.W., Frenkiel,T.A., Feeney,J., Freedman,R.B., Carr,M.D. and Williamson,R.A.
High resolution structure of the N-terminal domain of tissue inhibitor of metalloproteinases-2 and characterization of its interaction site with matrix metalloproteinase-3
J Biol Chem273, 21736-21743. PubMed Europe PubMed DOI S -
[YEAR:11-12-1998]Tuuttila,A., Morgunova,E., Bergmann,U., Lindqvist,Y., Maskos,K., Fernandez-Catalan,C., Bode,W., Tryggvason,K. and Schneider,G.
Three-dimensional structure of human tissue inhibitor of metalloproteinases-2 at 2.1 A resolution
J Mol Biol284, 1133-1140. PubMed Europe PubMed DOI S -
Gomez,D.E., Alonso,D.F., Yoshiji,H. and Thorgeirsson,U.P.
Tissue inhibitors of metalloproteinases: structure, regulation and biological functions
Eur J Cell Biol74, 111-122. PubMed Europe PubMed -
[YEAR:9-9-1996]Sato,H., Kinoshita,T., Takino,T., Nakayama,K. and Seiki,M.
Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2
FEBS Lett393, 101-104. PubMed Europe PubMed DOI -
[YEAR:1-6-1995]Itoh,Y., Binner,S. and Nagase,H.
Steps involved in activation of the complex of pro-matrix metalloproteinase 2 (progelatinase A) and tissue inhibitor of metalloproteinases (TIMP)-2 by 4-aminophenylmercuric acetate
Biochem J308, 645-651. PubMed Europe PubMed -
Murphy,G. and Willenbrock,F.
Tissue inhibitors of matrix metalloendopeptidases
Methods Enzymol248, 496-510. PubMed Europe PubMed DOI V -
De Clerck,Y.A., Darville,M.I., Eeckhout,Y. and Rousseau,G.G.
Characterization of the promoter of the gene encoding human tissue inhibitor of metalloproteinases-2 (TIMP-2)
Gene139, 185-191. PubMed Europe PubMed DOI -
[YEAR:4-10-1994]Williamson,R.A., Martorell,G., Carr,M.D., Murphy,G., Docherty,A.J., Freedman,R.B. and Feeney,J.
Solution structure of the active domain of tissue inhibitor of metalloproteinases-2. A new member of the OB fold protein family
Biochemistry33, 11745-11759. PubMed Europe PubMed DOI S -
Williamson,R.A., Bartels,H., Murphy,G. and Freedman,R.B.
Folding and stability of the active N-terminal domain of tissue inhibitor of metalloproteinases-1 and -2
Protein Eng7, 1035-1040. PubMed Europe PubMed -
Fridman,R., Bird,R.E., Hoyhtya,M., Oelkuct,M., Komarek,D., Liang,C.M., Berman,M.L., Liotta,L.A., Stetler-Stevenson,W.G. and Fuerst,T.R.
Expression of human recombinant 72 kDa gelatinase and tissue inhibitor of metalloproteinase-2 (TIMP-2): characterization of complex and free enzyme
Biochem J289, 411-416. PubMed Europe PubMed E -
Hill,P.A., Reynolds,J.J. and Meikle,M.C.
Inhibition of stimulated bone resorption in vitro by TIMP- 1 and TIMP-2
Biochim Biophys Acta1177, 71-74. PubMed Europe PubMed DOI -
[YEAR:27-4-1993]Willenbrock,F., Crabbe,T., Slocombe,P.M., Sutton,C.W., Docherty,A.J., Cockett,M.I., O'Shea,M., Brocklehurst,K., Phillips,I.R. and Murphy,G.
The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: a kinetic analysis of the inhibition of gelatinase A
Biochemistry32, 4330-4337. PubMed Europe PubMed -
Kleiner,D.E., Jr., Unsworth,E.J., Krutzsch,H.C. and Stetler-Stevenson,W.G.
Higher-order complex formation between the 72-kilodalton type IV collagenase and tissue inhibitor of metalloproteinases- 2
Biochemistry31, 1665-1672. PubMed Europe PubMed -
Roswit,W.T., McCourt,D.W., Partridge,N.C. and Jeffrey,J.J.
Purification and sequence analysis of two rat tissue inhibitors of metalloproteinases
Arch Biochem Biophys292, 402-410. PubMed Europe PubMed DOI -
Howard,E.W. and Banda,M.J.
Binding of tissue inhibitor of metalloproteinases 2 to two distinct sites on human 72-kDa gelatinase. Identification of a stabilization site
J Biol Chem266, 17972-17977. PubMed Europe PubMed -
Kolkenbrock,H., Orgel,D., Hecker-Kia,A., Noack,W. and Ulbrich,N.
The complex between a tissue inhibitor of metalloproteinases (TIMP-2) and 72-kDa progelatinase is a metalloproteinase inhibitor
Eur J Biochem198, 775-781. PubMed Europe PubMed -
Ward,R.V., Hembry,R.M., Reynolds,J.J. and Murphy,G.
The purification of tissue inhibitor of metalloproteinases- 2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases- 2 and tissue inhibitor of metalloproteinases-1
Biochem J278, 179-187. PubMed Europe PubMed -
[YEAR:15-10-1989]Stetler-Stevenson,W.G., Krutzsch,H.C. and Liotta,L.A.
Tissue inhibitor of metalloproteinase (TIMP-2). A new member of the metalloproteinase inhibitor family
J Biol Chem264, 17374-17378. PubMed Europe PubMed
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