Literature for inhibitor I32.003: BIRC-3 protein

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Inhibits Pharma

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    2024
  1. Acharya,R., Deb,P.K., Venugopala,K.N. and Pattanayak,S.P.
    An Azomethine Derivative, BCS3, Targets XIAP and cIAP1/2 to Arrest Breast Cancer Progression Through MDM2-p53 and Bcl-2-Caspase Signaling Modulation
    Pharmaceuticals (Basel) (2024) 17 PubMed  Europe PubMed DOI  PMC  EPMC
  2. 2022
  3. Wu,Y., Lu,S., Huang,X., Liu,Y., Huang,K., Liu,Z., Xu,W., Zhu,W., Hou,J., Liu,H. and Zhang,X.
    Targeting cIAPs attenuates CCl4-induced liver fibrosis by increasing MMP9 expression derived from neutrophils
    Life Sci (2022) 289, 120235-120235. PubMed  Europe PubMed DOI
  4. 2016
  5. Lee,E.W. and Song,J.
    USP11: a key regulator of cIAP2 stability and sensitivity to SMAC mimetics
    Mol Cell Oncol (2016) 3, e1029829-e1029829. PubMed  Europe PubMed DOI  PMC  EPMC
  6. 2015
  7. Lee,E.W., Seong,D., Seo,J., Jeong,M., Lee,H.K. and Song,J.
    USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics
    Cell Death Differ (2015) 22, 1463-1476. PubMed  Europe PubMed DOI
  8. 2014
  9. Kavanagh,E., Rodhe,J., Burguillos,M.A., Venero,J.L. and Joseph,B.
    Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
    Cell Death Dis (2014) 5, e1565-e1565. PubMed  Europe PubMed DOI
  10. 2011
  11. Dueber,E.C., Schoeffler,A.J., Lingel,A., Elliott,J.M., Fedorova,A.V., Giannetti,A.M., Zobel,K., Maurer,B., Varfolomeev,E., Wu,P., Wallweber,H.J., Hymowitz,S.G., Deshayes,K., Vucic,D. and Fairbrother,W.J.
    Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination
    Science (2011) 334, 376-380. PubMed  Europe PubMed DOI
  12. Labbe,K., McIntire,C.R., Doiron,K., Leblanc,P.M. and Saleh,M.
    Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome
    Immunity (2011) 35, 897-907. PubMed  Europe PubMed DOI
  13. 2009
  14. Herman,M.D., Moche,M., Flodin,S., Welin,M., Tresaugues,L., Johansson,I., Nilsson,M., Nordlund,P. and Nyman,T.
    Structures of BIR domains from human NAIP and cIAP2
    Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 65, 1091-1096. PubMed  Europe PubMed DOI  PMC  EPMC  S
  15. 2008
  16. Varfolomeev,E., Goncharov,T., Fedorova,A.V., Dynek,J.N., Zobel,K., Deshayes,K., Fairbrother,W.J. and Vucic,D.
    c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation
    J Biol Chem (2008) 283, 24295-24299. PubMed  Europe PubMed DOI
  17. 2007
  18. Inagaki,H.
    Mucosa-associated lymphoid tissue lymphoma: molecular pathogenesis and clinicopathological significance
    Pathol Int (2007) 57, 474-484. PubMed  Europe PubMed DOI
  19. Murga Penas,E.M., Callet-Bauchu,E., Ye,H., Hinz,K., Albert,N., Copie-Bergman,C., Gazzo,S., Berger,F., Salles,G., Bokemeyer,C., Du,M.Q. and Dierlamm,J.
    The translocations t(6;18;11)(q24;q21;q21) and t(11;14;18)(q21;q32;q21) lead to a fusion of the API2 and MALT1 genes and occur in MALT lymphomas
    Haematologica (2007) 92, 405-409. PubMed  Europe PubMed DOI
  20. 2006
  21. [YEAR:25-11-2006]Durkop,H., Hirsch,B., Hahn,C. and Stein,H.
    cIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3
    J Mol Med (Berl) (25-11-2006) 84, 132-141. PubMed  Europe PubMed DOI
  22. [YEAR:8-12-2006]Eckelman,B.P. and Salvesen,G.S.
    The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases
    J Biol Chem (8-12-2006) 281, 3254-3260. PubMed  Europe PubMed DOI
  23. 2002
  24. Hofmann,H.S., Simm,A., Hammer,A., Silber,R.E. and Bartling,B.
    Expression of inhibitors of apoptosis (IAP) proteins in non-small cell human lung cancer
    J Cancer Res Clin Oncol (2002) 128, 554-560. PubMed  Europe PubMed DOI
  25. 2000
  26. [YEAR:1-9-2000]Huang,H., Joazeiro,C.A., Bonfoco,E., Kamada,S., Leverson,J.D. and Hunter,T.
    The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
    J Biol Chem (1-9-2000) 275, 26661-26664. PubMed  Europe PubMed DOI
  27. 1999
  28. Dierlamm,J., Baens,M., Wlodarska,I., Stefanova-Ouzounova,M., Hernandez,J.M., Hossfeld,D.K., De Wolf-Peeters,C., Hagemeijer,A., Van Den Berghe,H. and Marynen,P.
    The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas
    Blood (1999) 93, 3601-3609. PubMed  Europe PubMed
  29. 1998
  30. [YEAR:15-4-1998]Deveraux,Q.L., Roy,N., Stennicke,H.R., Van Arsdale,T., Zhou,Q., Srinivasula,S.M., Alnemri,E.S., Salvesen,G.S. and Reed,J.C.
    IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
    EMBO J (15-4-1998) 17, 2215-2223. PubMed  Europe PubMed DOI  PMC  EPMC
  31. 1997
  32. [YEAR:1-12-1997]Roy,N., Deveraux,Q.L., Takahashi,R., Salvesen,G.S. and Reed,J.C.
    The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
    EMBO J (1-12-1997) 16, 6914-6925. PubMed  Europe PubMed DOI  PMC  EPMC
  33. 1996
  34. [YEAR:1-11-1996]Rajcan-Separovic,E., Liston,P., Lefebvre,C. and Korneluk,R.G.
    Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization
    Genomics (1-11-1996) 37, 404-406. PubMed  Europe PubMed DOI
  35. Uren,A.G., Pakusch,M., Hawkins,C.J., Puls,K.L. and Vaux,D.L.
    Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
    Proc Natl Acad Sci U S A (1996) 93, 4974-4978. PubMed  Europe PubMed  PMC  EPMC