Literature for inhibitor I32.003: BIRC-3 protein

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Pharma

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    2022
  1. Wu,Y., Lu,S., Huang,X., Liu,Y., Huang,K., Liu,Z., Xu,W., Zhu,W., Hou,J., Liu,H. and Zhang,X.
    Targeting cIAPs attenuates CCl4-induced liver fibrosis by increasing MMP9 expression derived from neutrophils
    Life Sci289, 120235-120235. PubMed  Europe PubMed DOI
  2. 2016
  3. Lee,E.W. and Song,J.
    USP11: a key regulator of cIAP2 stability and sensitivity to SMAC mimetics
    Mol Cell Oncol3, e1029829-e1029829. PubMed  Europe PubMed DOI
  4. 2015
  5. Lee,E.W., Seong,D., Seo,J., Jeong,M., Lee,H.K. and Song,J.
    USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics
    Cell Death Differ22, 1463-1476. PubMed  Europe PubMed DOI
  6. 2014
  7. Kavanagh,E., Rodhe,J., Burguillos,M.A., Venero,J.L. and Joseph,B.
    Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
    Cell Death Dis5, e1565-e1565. PubMed  Europe PubMed DOI
  8. 2011
  9. Dueber,E.C., Schoeffler,A.J., Lingel,A., Elliott,J.M., Fedorova,A.V., Giannetti,A.M., Zobel,K., Maurer,B., Varfolomeev,E., Wu,P., Wallweber,H.J., Hymowitz,S.G., Deshayes,K., Vucic,D. and Fairbrother,W.J.
    Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination
    Science334, 376-380. PubMed  Europe PubMed DOI
  10. Labbe,K., McIntire,C.R., Doiron,K., Leblanc,P.M. and Saleh,M.
    Cellular inhibitors of apoptosis proteins cIAP1 and cIAP2 are required for efficient caspase-1 activation by the inflammasome
    Immunity35, 897-907. PubMed  Europe PubMed DOI
  11. 2009
  12. Herman,M.D., Moche,M., Flodin,S., Welin,M., Tresaugues,L., Johansson,I., Nilsson,M., Nordlund,P. and Nyman,T.
    Structures of BIR domains from human NAIP and cIAP2
    Acta Crystallogr Sect F Struct Biol Cryst Commun65, 1091-1096. PubMed  Europe PubMed DOI  S
  13. 2008
  14. Varfolomeev,E., Goncharov,T., Fedorova,A.V., Dynek,J.N., Zobel,K., Deshayes,K., Fairbrother,W.J. and Vucic,D.
    c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor alpha (TNFalpha)-induced NF-kappaB activation
    J Biol Chem283, 24295-24299. PubMed  Europe PubMed DOI
  15. 2007
  16. Inagaki,H.
    Mucosa-associated lymphoid tissue lymphoma: molecular pathogenesis and clinicopathological significance
    Pathol Int57, 474-484. PubMed  Europe PubMed DOI
  17. Murga Penas,E.M., Callet-Bauchu,E., Ye,H., Hinz,K., Albert,N., Copie-Bergman,C., Gazzo,S., Berger,F., Salles,G., Bokemeyer,C., Du,M.Q. and Dierlamm,J.
    The translocations t(6;18;11)(q24;q21;q21) and t(11;14;18)(q21;q32;q21) lead to a fusion of the API2 and MALT1 genes and occur in MALT lymphomas
    Haematologica92, 405-409. PubMed  Europe PubMed DOI
  18. 2006
  19. [YEAR:25-11-2006]Durkop,H., Hirsch,B., Hahn,C. and Stein,H.
    cIAP2 is highly expressed in Hodgkin-Reed-Sternberg cells and inhibits apoptosis by interfering with constitutively active caspase-3
    J Mol Med (Berl)84, 132-141. PubMed  Europe PubMed DOI
  20. [YEAR:8-12-2006]Eckelman,B.P. and Salvesen,G.S.
    The human anti-apoptotic proteins cIAP1 and cIAP2 bind but do not inhibit caspases
    J Biol Chem281, 3254-3260. PubMed  Europe PubMed DOI
  21. 2002
  22. Hofmann,H.S., Simm,A., Hammer,A., Silber,R.E. and Bartling,B.
    Expression of inhibitors of apoptosis (IAP) proteins in non-small cell human lung cancer
    J Cancer Res Clin Oncol128, 554-560. PubMed  Europe PubMed DOI
  23. 2000
  24. [YEAR:1-9-2000]Huang,H., Joazeiro,C.A., Bonfoco,E., Kamada,S., Leverson,J.D. and Hunter,T.
    The inhibitor of apoptosis, cIAP2, functions as a ubiquitin-protein ligase and promotes in vitro monoubiquitination of caspases 3 and 7
    J Biol Chem275, 26661-26664. PubMed  Europe PubMed DOI
  25. 1999
  26. Dierlamm,J., Baens,M., Wlodarska,I., Stefanova-Ouzounova,M., Hernandez,J.M., Hossfeld,D.K., De Wolf-Peeters,C., Hagemeijer,A., Van Den Berghe,H. and Marynen,P.
    The apoptosis inhibitor gene API2 and a novel 18q gene, MLT, are recurrently rearranged in the t(11;18)(q21;q21) associated with mucosa-associated lymphoid tissue lymphomas
    Blood93, 3601-3609. PubMed  Europe PubMed
  27. 1998
  28. [YEAR:15-4-1998]Deveraux,Q.L., Roy,N., Stennicke,H.R., Van Arsdale,T., Zhou,Q., Srinivasula,S.M., Alnemri,E.S., Salvesen,G.S. and Reed,J.C.
    IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
    EMBO J17, 2215-2223. PubMed  Europe PubMed DOI
  29. 1997
  30. [YEAR:1-12-1997]Roy,N., Deveraux,Q.L., Takahashi,R., Salvesen,G.S. and Reed,J.C.
    The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
    EMBO J16, 6914-6925. PubMed  Europe PubMed DOI
  31. 1996
  32. [YEAR:1-11-1996]Rajcan-Separovic,E., Liston,P., Lefebvre,C. and Korneluk,R.G.
    Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization
    Genomics37, 404-406. PubMed  Europe PubMed DOI
  33. Uren,A.G., Pakusch,M., Hawkins,C.J., Puls,K.L. and Vaux,D.L.
    Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors
    Proc Natl Acad Sci U S A93, 4974-4978. PubMed  Europe PubMed