Literature for I25.UPB: subfamily I25B unassigned peptidase inhibitors

(Topics flags: S Structure, E Expression, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Cassiano,A.F.B., Souza,E.P., Coaguila-Llerena,H., Henrique-Silva,F. and Faria,G.
   Effect of sugarcane cystatin CaneCPI-5 on osteogenic differentiation of human dental pulp cells
   Braz Dent J (2025) 36, e236174-e236174. PubMed  Europe PubMed DOI  PMC  EPMC
2. Lee,G.H., Kang,Y.J., Jin,H.B. and Park,H.H.
   Two different domain swapped dimer structures were revealed by crystal structure of EPIC1 from Phytophthora nicotianae
   Biochem Biophys Res Commun (2025) 781, 152543-152543. PubMed  Europe PubMed DOI
3. Yao,S., Zhang,R., Ma,S., Zhao,T., Liu,Q., Zhu,L., Liu,C., Sun,L. and Du,M.
   A Novel Cystatin Gene from Sea Cucumber (Apostichopus japonicus): Characterization and Comparative Expression with Cathepsin L During Early Stage of Hypoxic Exposure-Induced Autolysis
   Foods (2025) 14 PubMed  Europe PubMed DOI  PMC  EPMC
2024
4. Acevedo,N., Lozano,A., Zakzuk,J., Llinas-Caballero,K., Brodin,D., Nejsum,P., Williams,A.R. and Caraballo,L.
   Cystatin from the helminth Ascaris lumbricoides upregulates mevalonate and cholesterol biosynthesis pathways and immunomodulatory genes in human monocyte-derived dendritic cells
   Front Immunol (2024) 15, 1328401-1328401. PubMed  Europe PubMed DOI  PMC  EPMC
2023
5. Fang,M., Cha,J.H., Wang,H.C., Ye,P., Chen,B., Chen,M., Yang,W.H. and Yan,X.
   An undefined cystatin CsCPI1 from tea plant Camellia sinensis harbors antithrombotic activity
   Biomed Pharmacother (2023) 159, 114285-114285. PubMed  Europe PubMed DOI
2022
6. Xu,S., Wang,Y., Han,C., Jiang,Y., Qin,Q. and Wei,S.
   Functional analysis of the Cystatin F gene response to SGIV infection in orange-spotted grouper, Epinephelus coioides
   Fish Shellfish Immunol (2022) 130, 43-52. PubMed  Europe PubMed DOI
2021
7. Caraballo,L., Zakzuk,J. and Acevedo,N.
   Helminth-derived cystatins: the immunomodulatory properties of an Ascaris lumbricoides cystatin
   Parasitology (2021) , 1-13. PubMed  Europe PubMed DOI  V
8. Chen,Y., Wei,B., Xu,P., Tang,H., Yang,L., Wang,Y., Fu,Y., Yang,X. and Mao,Y.
   Schistosoma japonicum cystatin suppresses osteoclastogenesis via manipulating the NFkappaB signaling pathway
   Mol Med Rep (2021) 23, 1-1. PubMed  Europe PubMed DOI
9. Nie,J., Shan,N., Liu,H., Yao,X., Wang,Z., Bai,R., Guo,Y., Duan,Y., Wang,C. and Sui,X.
   Transcriptional control of local auxin distribution by the CsDFB1-CsPHB module regulates floral organogenesis in cucumber
   Proc Natl Acad Sci U S A (2021) 118 PubMed  Europe PubMed DOI  PMC  EPMC
2020
10. [YEAR:1-6-2020]Schneider,V.K., da Silva Ferrara,T.F., Rocha,S.V., Santos-Júnior,C.D., Neo-Justino,D.M., da Cunha,A.F., de Oliveira da Silva JPM, Dos Santos Tersariol,I.L., Carmona,A.K., Henrique-Silva,F. and Soares-Costa,A.
    Recombinant expression, characterization and phylogenetic studies of novels cystatins-like proteins of sweet orange (Citrus sinensis) and clementine (Citrus clementina)
    Int J Biol Macromol (1-6-2020) 152, 546-553. PubMed  Europe PubMed
2019
11. Dong,X., Xu,J., Song,H., Liu,Y., Wu,M., Zhang,H., Jing,B., Lai,W., Gu,X., Xie,Y., Peng,X. and Yang,G.
    Molecular characterization of a Dirofilaria immitis cysteine protease inhibitor (cystatin) and its possible role in filarial immune evasion
    Genes (Basel) (2019) 10 PubMed  Europe PubMed DOI
2018
12. Christova,P.K., Christov,N.K., Mladenov,P.V. and Imai,R.
    The wheat multidomain cystatin TaMDC1 displays antifungal, antibacterial, and insecticidal activities in planta
    Plant Cell Rep (2018) 37, 923-932. PubMed  Europe PubMed DOI
13. Sanchez-Rodriguez,D.B., Ortega-Lopez,J., Cardenas-Guerra,R.E., Resendiz-Cardiel,G., Chavez-Munguia,B., Lagunes-Guillen,A. and Arroyo,R.
    Characterization of a novel endogenous cysteine proteinase inhibitor, trichocystatin-3 (TC-3), localized on the surface of Trichomonas vaginalis
    Int J Biochem Cell Biol (2018) 102, 87-100. PubMed  Europe PubMed DOI
2017
14. Li,H., Wang,S., Zhan,B., He,W., Chu,L., Qiu,D., Li,N., Wan,Y., Zhang,H., Chen,X., Fang,Q., Shen,J. and Yang,X.
    Therapeutic effect of Schistosoma japonicum cystatin on bacterial sepsis in mice
    Parasit Vectors (2017) 10, 222-222. PubMed  Europe PubMed DOI  PMC  EPMC  U
15. Zavasnik-Bergant,T., Vidmar,R., Sekirnik,A., Fonovic,M., Salat,J., Grunclova,L., Kopacek,P. and Turk,B.
    Salivary tick cystatin OmC2 targets lysosomal cathepsins S and C in human dendritic cells
    Front Cell Infect Microbiol (2017) 7, 288-288. PubMed  Europe PubMed DOI  PMC  EPMC
2016
16. Liu,F., Cheng,W., Pappoe,F., Hu,X., Wen,H., Luo,Q., Wang,S., Deng,F., Xie,Y., Xu,Y. and Shen,J.
    Schistosoma japonicum cystatin attenuates murine collagen-induced arthritis
    Parasitol Res (2016) 115, 3795-3806. PubMed  Europe PubMed DOI
2015
17. Lima,A.M., Dos Reis,S.P. and de Souza,C.R.
    Phytocystatins and their potential to control plant diseases caused by fungi
    Protein Pept Lett (2015) 22, 104-111. PubMed  Europe PubMed  V
18. Wan,H., Kang,T., Kim,B.Y., Lee,K.S., Li,J. and Jin,B.R.
    AvCystatin, a novel cysteine protease inhibitor from spider (Araneus ventricosus) venom
    J Asia-Pac Entomol (2015) 18, 13-18. DOI
19. Yadav,V.K., Mandal,R.S., Puniya,B.L., Kumar,R., Dey,S., Singh,S. and Yadav,S.
    Structural and binding studies of SAP-1 protein with heparin
    Chem Biol Drug Des (2015) 85, 404-410. PubMed  Europe PubMed DOI
2014
20. Chan,S.-N., Abu Bakar,N., Mahmood,M., Ho,C.-L. and Shaharuddin,N.A.
    Molecular cloning and characterization of novel phytocystatin gene from turmeric, Curcuma longa
    Biomed Res Int (2014) 2014, Article ID 973790- PubMed  Europe PubMed DOI
21. Geadkaew,A., Kosa,N., Siricoon,S., Grams,S.V. and Grams,R.
    A 170kDa multi-domain cystatin of Fasciola gigantica is active in the male reproductive system
    Mol Biochem Parasitol (2014) 196, 100-107. PubMed  Europe PubMed DOI
22. Je,J., Song,C., Hwang,J.E., Chung,W.S. and Lim,C.O.
    DREB2C acts as a transcriptional activator of the thermo tolerance-related phytocystatin 4 (AtCYS4) gene
    Transgenic Res (2014) 23, 109-123. PubMed  Europe PubMed DOI
23. Lin,S., Yuan,Y., Ren,X., Zou,J., Li,R., Guo,Y., Zhao,J. and Wang,R.
    Cloning and tissue expression of cysteine proteinase inhibitor (CPI) gene family in Nicotiana tabacum L
    Acta Tabacaria Sin (2014) 20, 79-87. DOI
24. Lu,S., Soares,T.S., Vaz Junior,I.S., Lovato,D.V. and Tanaka,A.S.
    Rmcystatin3, a cysteine protease inhibitor from Rhipicephalus microplus hemocytes involved in immune response
    Biochimie (2014) 106, 17-23. PubMed  Europe PubMed DOI
25. Puente-Rivera,J., de Los Angeles Ramon-Luing,L., Figueroa-Angulo,E.E., Ortega-Lopez,J. and Arroyo,R.
    Trichocystatin-2 (TC-2): an endogenous inhibitor of cysteine proteinases in Trichomonas vaginalis is associated with TvCP39
    Int J Biochem Cell Biol (2014) 54, 255-265. PubMed  Europe PubMed DOI
26. Yang,X., Liu,J., Yue,Y., Chen,W., Song,M., Zhan,X. and Wu,Z.
    Cloning, expression and characterisation of a type II cystatin from Schistosoma japonicum, which could regulate macrophage activation
    Parasitol Res (2014) 113, 3985-3992. PubMed  Europe PubMed DOI
27. Zhao,P., Zhou,X.M., Zou,J., Wang,W., Wang,L., Peng,X.B. and Sun,M.X.
    Comprehensive analysis of cystatin family genes suggests their putative functions in sexual reproduction, embryogenesis, and seed formation
    J Exp Bot (2014) 65, 5093-5107. PubMed  Europe PubMed DOI
2013
28. Imamura,S., Konnai,S., Yamada,S., Parizi,L.F., Githaka,N., Vaz,I.S., Jr., Murata,S. and Ohashi,K.
    Identification and partial characterization of a gut Rhipicephalus appendiculatus cystatin
    Ticks Tick Borne Dis (2013) 4, 138-144. PubMed  Europe PubMed DOI
29. Mohindra,V., Tripathi,R.K., Singh,A. and Singh,B.
    Molecular characterization and expression analysis of a novel cystatin-like gene in a hypoxia-tolerant Indian catfish, Clarias batrachus [Linnaeus, 1758]
    Fish Shellfish Immunol (2013) 34, 683-687. PubMed  Europe PubMed DOI
30. Parizi,L.F., Githaka,N.W., Acevedo,C., Benavides,U., Seixas,A., Logullo,C., Konnai,S., Ohashi,K., Masuda,A. and da Silva Vaz,I., Jr.
    Sequence characterization and immunogenicity of cystatins from the cattle tick Rhipicephalus (Boophilus) microplus
    Ticks Tick Borne Dis (2013) 4, 492-499. PubMed  Europe PubMed DOI
31. Porruana,R., Chundetb,R. and Anuntalabhochaia,S.
    Characterization of a cDNA encoding cystatin with antifungal activity from Siam tulip Curcuma alismatifolia
    ScienceAsia (2013) 39, 596-604. DOI
32. Raimbault,A.K., Zuily-Fodil,Y., Soler,A., Mora,P. and Cruz de Carvalho,M.H.
    The expression patterns of bromelain and AcCYS1 correlate with blackheart resistance in pineapple fruits submitted to postharvest chilling stress
    J Plant Physiol (2013) 170, 1442-1446. PubMed  Europe PubMed DOI
2012
33. Irene,D., Chung,T.Y., Chen,B.J., Liu,T.H., Li,F.Y., Tzen,J.T., Wang,C.I. and Chyan,C.L.
    Solution structure of a phytocystatin from Ananas comosus and its molecular interaction with papain
    PLoS ONE (2012) 7, e47865-e47865. PubMed  Europe PubMed DOI  PMC  EPMC  S
2011
34. Buarque,D.S., Spindola,L.M., Martins,R.M., Braz,G.R. and Tanaka,A.S.
    Tigutcystatin, a cysteine protease inhibitor from Triatoma infestans midgut expressed in response to Trypanosoma cruzi
    Biochem Biophys Res Commun (2011) 413, 241-247. PubMed  Europe PubMed DOI
35. Gholizadeh,A. and Kohnehrouz,B.B.
    Functional fusion expression of sunflower multicystatin in E. coli and its comparison with a single domain cystatin
    Indian J Geo Mar Sci (2011) 48, 375-379.  E
36. Richards,R., St Pierre,L., Trabi,M., Johnson,L.A., de Jersey,J., Masci,P.P. and Lavin,M.F.
    Cloning and characterisation of novel cystatins from elapid snake venom glands
    Biochimie (2011) 93, 659-668. PubMed  Europe PubMed DOI
2009
37. Li,S., Ao,J. and Chen,X.
    Molecular and functional characterization of a cystatin analogue in large yellow croaker (Pseudosciaena crocea)
    Mol Immunol (2009) 46, 1638-1646. PubMed  Europe PubMed DOI
38. Martinez,M., Cambra,I., Carrillo,L., Diaz-Mendoza,M. and Diaz,I.
    Characterization of the entire cystatin gene family in barley and their target cathepsin L-like cysteine-proteases, partners in the hordein mobilization during seed germination
    Plant Physiol (2009) 151, 1531-1545. PubMed  Europe PubMed DOI  PMC  EPMC
39. Neuteboom,L.W., Matsumoto,K.O. and Christopher,D.A.
    An extended AE-rich N-terminal trunk in secreted pineapple cystatin enhances inhibition of fruit bromelain and is posttranslationally removed during ripening
    Plant Physiol (2009) 151, 515-527. PubMed  Europe PubMed DOI  PMC  EPMC
40. Yamaji,K., Tsuji,N., Miyoshi,T., Islam,M.K., Hatta,T., Alim,M.A., Anisuzzaman,M., Kushibiki,S. and Fujisaki,K.
    A salivary cystatin, HlSC-1, from the ixodid tick Haemaphysalis longicornis play roles in the blood-feeding processes
    Parasitol Res (2009) 106, 61-68. PubMed  Europe PubMed DOI
2008
41. Schnoeller,C., Rausch,S., Pillai,S., Avagyan,A., Wittig,B.M., Loddenkemper,C., Hamann,A., Hamelmann,E., Lucius,R. and Hartmann,S.
    A helminth immunomodulator reduces allergic and inflammatory responses by induction of IL-10-producing macrophages
    J Immunol (2008) 180, 4265-4272. PubMed  Europe PubMed
2007
42. Rodriguez-Mahillo,A.I., Gonzalez-Munoz,M., Gomez-Aguado,F., Rodriguez-Perez,R., Corcuera,M.T., Caballero,M.L. and Moneo,I.
    Cloning and characterisation of the Anisakis simplex allergen Ani s 4 as a cysteine-protease inhibitor
    Int J Parasitol (2007) 37, 907-917. PubMed  Europe PubMed DOI
2006
43. Christova,P.K., Christov,N.K. and Imai,R.
    A cold inducible multidomain cystatin from winter wheat inhibits growth of the snow mold fungus, Microdochium nivale
    Planta (2006) 223, 1207-1218. PubMed  Europe PubMed DOI
44. Grunclova,L., Horn,M., Vancova,M., Sojka,D., Franta,Z., Mares,M. and Kopacek,P.
    Two secreted cystatins of the soft tick Ornithodoros moubata: differential expression pattern and inhibitory specificity
    Biol Chem (2006) 387, 1635-1644. PubMed  Europe PubMed DOI
2005
45. [YEAR:9-8-2005]Pillai,S., Kalinna,B.H., Liebau,E., Hartmann,S., Theuring,F. and Lucius,R.
    Studies on Acanthocheilonema viteae cystatin: genomic organization, promoter studies and expression in Caenorhabditis elegans
    Filaria J (9-8-2005) 4, 9-9. PubMed  Europe PubMed DOI  PMC  EPMC
2004
46. Shyu,D.J., Chyan,C.L., Tzen,J.T. and Chou,W.M.
    Molecular cloning, expression, and functional characterization of a cystatin from pineapple stem
    Biosci Biotechnol Biochem (2004) 68, 1681-1689. PubMed  Europe PubMed DOI
2003
47. Belenghi,B., Acconcia,F., Trovato,M., Perazzolli,M., Bocedi,A., Polticelli,F., Ascenzi,P. and Delledonne,M.
    AtCYS1, a cystatin from Arabidopsis thaliana, suppresses hypersensitive cell death
    Eur J Biochem (2003) 270, 2593-2604. PubMed  Europe PubMed DOI
48. [YEAR:31-1-2003]Sun,H., Li,N., Wang,X., Liu,S., Chen,T., Zhang,L., Wan,T. and Cao,X.
    Molecular cloning and characterization of a novel cystatin-like molecule, CLM, from human bone marrow stromal cells
    Biochem Biophys Res Commun (31-1-2003) 301, 176-182. PubMed  Europe PubMed DOI
2002
49. Vray,B., Hartmann,S. and Hoebeke,J.
    Immunomodulatory properties of cystatins
    Cell Mol Life Sci (2002) 59, 1503-1512. PubMed  Europe PubMed DOI
2001
50. Tzeng,S.S., Chen,G.H., Chung,Y.C. and Jiang,S.T.
    Expression of soluble form carp (Cyprinus carpio) ovarian cystatin in Escherichia coli and its purification
    J Agric Food Chem (2001) 49, 4224-4230. PubMed  Europe PubMed DOI
51. Ylonen,A., Kalkkinen,N., Saarinen,J., Bogwald,J. and Helin,J.
    Glycosylation analysis of two cysteine proteinase inhibitors from Atlantic salmon skin: di-O-acetylated sialic acids are the major sialic acid species on N-glycans
    Glycobiology (2001) 11, 523-531. PubMed  Europe PubMed
1994
52. Dickinson,D.P., Zhao,Y., Thiesse,M. and Siciliano,M.J.
    Direct mapping of seven genes encoding human type 2 cystatins to a single site located at 20p11.2
    Genomics (1994) 24, 172-175. PubMed  Europe PubMed DOI
1987
53. Ritonja,A., Evans,H.J., Machleidt,W. and Barrett,A.J.
    Amino acid sequence of a cystatin from venom of the African puff adder (Bitis arietans)
    Biochem J (1987) 246, 799-802. PubMed  Europe PubMed  PMC  EPMC
1979
54. [YEAR:1-1-1979]Willadsen,P. and Riding,G.A.
    Characterization of a proteolytic-enzyme inhibitor with allergenic activity. Multiple functions of a parasite-derived protein
    Biochem J (1-1-1979) 177, 41-47. PubMed  Europe PubMed  PMC  EPMC