Literature for I25.UPA: subfamily I25A unassigned peptidase inhibitors

Summary Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, K Knockout, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Wang,Y.X., Ma,Y.D., Li,H.H., Duo,W.J., Jin,Q.W., Zhou,K.J., Gao,Y.R., He,J.N., Xie,Y.J., Chu,L. and Yang,X.D.
    Schistosoma japonicum cystatin attenuated CLP-induced sepsis in mice though inducing tolerogenic dendritic cells and regulatory T cells
    Comp Immunol Microbiol Infect Dis120, 102345-102345. PubMed  Europe PubMed DOI
  2. 2024
  3. Du,R., Zheng,X., Liu,Y., Lu,P., Hong,Y. and Wang,P.
    Molecular and functional characterization of a type-1 cystatin in amphioxus (Branchiostoma japonicum)
    Fish Shellfish Immunol147, 109423-109423. PubMed  Europe PubMed DOI
  4. 2023
  5. Busa,M., Matouskova,Z., Bartosova-Sojkova,P., Pachl,P., Rezacova,P., Eichenberger,R.M., Deplazes,P., Horn,M., Stefanic,S. and Mares,M.
    An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily
    J Biol Chem299, 102970-102970. PubMed  Europe PubMed DOI
  6. 2022
  7. Zhang,K., Liu,Y., Zhang,G., Wang,X., Li,Z., Shang,Y., Ning,C., Ji,C., Cai,X., Xia,X., Qiao,J. and Meng,Q.
    Molecular Characteristics and Potent Immunomodulatory Activity of Fasciola hepatica Cystatin
    Korean J Parasitol60, 117-126. PubMed  Europe PubMed DOI
  8. 2021
  9. Chen,Y., Wei,B., Xu,P., Tang,H., Yang,L., Wang,Y., Fu,Y., Yang,X. and Mao,Y.
    Schistosoma japonicum cystatin suppresses osteoclastogenesis via manipulating the NFkappaB signaling pathway
    Mol Med Rep23, 1-1. PubMed  Europe PubMed DOI
  10. Xie,H., Wu,L., Chen,X., Gao,S., Li,H., Yuan,Y., Liang,J., Wang,X., Wang,S., Xu,C., Chu,L., Zhan,B., Zhou,R. and Yang,X.
    Schistosoma japonicum Cystatin Alleviates Sepsis Through Activating Regulatory Macrophages
    Front Cell Infect Microbiol11, 617461-617461. PubMed  Europe PubMed DOI
  11. 2020
  12. Kobpornchai,P., Flynn,R.J., Reamtong,O., Rittisoonthorn,N., Kosoltanapiwat,N., Boonnak,K., Boonyuen,U., Ampawong,S., Jiratanh,M., Tattiyapong,M. and Adisakwattana,P.
    A novel cystatin derived from Trichinella spiralis suppresses macrophage-mediated inflammatory responses
    PLoS Negl Trop Dis14, e0008192-e0008192. PubMed  Europe PubMed DOI
  13. Lu,S., Ascencio,M.E., Torquato,R.J.S., Florin-Christensen,M. and Tanaka,A.S.
    Kinetic characterization of a novel cysteine peptidase from the protozoan Babesia bovis, a potential target for drug design
    Biochimie179, 127-134. PubMed  Europe PubMed DOI
  14. Lu,S., da Rocha,L.A., Torquato,R.J.S., da Silva Vaz Junior,I., Florin-Christensen,M. and Tanaka,A.S.
    A novel type 1 cystatin involved in the regulation of Rhipicephalus microplus midgut cysteine proteases
    Ticks Tick Borne Dis101374-101374. PubMed  Europe PubMed DOI
  15. Thai,T.L., Kang,J.M., Le,H.G., Lee,J., Yoo,W.G., Shin,H.J., Sohn,W.M. and Na,B.K.
    Fowlerstefin, a cysteine protease inhibitor of Naegleria fowleri, induces inflammatory responses in BV-2 microglial cells in vitro
    Parasit Vectors13, 41-41. PubMed  Europe PubMed DOI
  16. 2019
  17. Liu,J., Svard,S.G. and Klotz,C.
    Giardia intestinalis cystatin is a potent inhibitor of papain, parasite cysteine proteases and, to a lesser extent, human cathepsin B
    FEBS Lett593, 1313-1325. PubMed  Europe PubMed DOI
  18. Xu,J., Liu,M., Yu,P., Wu,L. and Lu,Y.
    Effect of recombinant Trichinella spiralis cysteine proteinase inhibitor on TNBS-induced experimental inflammatory bowel disease in mice
    Int Immunopharmacol66, 28-40. PubMed  Europe PubMed DOI
  19. Xue,Q. and Wu,X.Q.
    Characteristics and function of a novel cystatin gene in the pine wood nematode Bursaphelenchus xylophilus
    Biol Open8, PubMed  Europe PubMed DOI
  20. 2018
  21. Park,S.Y., Jeong,M.S., Park,S.A., Ha,S.C., Na,B.K. and Jang,S.B.
    Structural basis of the cystein protease inhibitor Clonorchis sinensis stefin-1
    Biochem Biophys Res Commun498, 9-17. PubMed  Europe PubMed DOI  S
  22. 2017
  23. Ilgova,J., Jedlickova,L., Dvorakova,H., Benovics,M., Mikes,L., Janda,L., Vorel,J., Roudnicky,P., Potesil,D., Zdrahal,Z., Gelnar,M. and Kasny,M.
    A novel type I cystatin of parasite origin with atypical legumain-binding domain
    Sci Rep7, 17526-17526. PubMed  Europe PubMed DOI
  24. 2016
  25. Wang,S., Xie,Y., Yang,X., Wang,X., Yan,K., Zhong,Z., Wang,X., Xu,Y., Zhang,Y., Liu,F. and Shen,J.
    Therapeutic potential of recombinant cystatin from Schistosoma japonicum in TNBS-induced experimental colitis of mice
    Parasit Vectors9, 6-6. PubMed  Europe PubMed DOI  U
  26. 2014
  27. Kang,J.M., Ju,H.L., Lee,K.H., Kim,T.S., Pak,J.H., Sohn,W.M. and Na,B.K.
    Identification and characterization of the second cysteine protease inhibitor of Clonorchis sinensis (CsStefin-2)
    Parasitol Res113, 47-58. PubMed  Europe PubMed DOI
  28. 2013
  29. Ibelli,A.M., Hermance,M.M., Kim,T.K., Gonzalez,C.L. and Mulenga,A.
    Bioinformatics and expression analyses of the Ixodes scapularis tick cystatin family
    Exp Appl Acarol60, 41-53. PubMed  Europe PubMed DOI
  30. Lee,J.Y., Song,S.M., Moon,E.K., Lee,Y.R., Jha,B.K., Danne,D.B., Cha,H.J., Yu,H.S., Kong,H.H., Chung,D.I. and Hong,Y.
    Cysteine protease inhibitor (AcStefin) is required for complete cyst formation of Acanthamoeba
    Eukaryot Cell12, 567-574. PubMed  Europe PubMed DOI
  31. 2011
  32. He,B., Cai,G., Ni,Y., Li,Y., Zong,H. and He,L.
    Characterization and expression of a novel cystatin gene from Schistosoma japonicum
    Mol Cell Probes25, 186-193. PubMed  Europe PubMed DOI
  33. Jang,S.W., Cho,M.K., Park,M.K., Kang,S.A., Na,B.K., Ahn,S.C., Kim,D.H. and Yu,H.S.
    Parasitic helminth cystatin inhibits DSS-induced intestinal inflammation via IL-10(+)F4/80(+) macrophage recruitment
    Korean J Parasitol49, 245-254. PubMed  Europe PubMed DOI
  34. Kang,J.M., Lee,K.H., Sohn,W.M. and Na,B.K.
    Identification and functional characterization of CsStefin-1, a cysteine protease inhibitor of Clonorchis sinensis
    Mol Biochem Parasitol177, 126-134. PubMed  Europe PubMed DOI
  35. 2010
  36. Li,F., Gai,X., Wang,L., Song,L., Zhang,H., Qiu,L., Wang,M. and Siva,V.S.
    Identification and characterization of a cystatin gene from Chinese mitten crab Eriocheir sinensis
    Fish Shellfish Immunol29, 521-529. PubMed  Europe PubMed DOI
  37. 2009
  38. Bilodeau,M., MacRae,T., Gaboury,L., Laverdure,J.P., Hardy,M.P., Mayotte,N., Paradis,V., Harton,S., Perreault,C. and Sauvageau,G.
    Analysis of blood stem cell activity and cystatin gene expression in a mouse model presenting a chromosomal deletion encompassing Csta and Stfa2l1
    PLoS ONE4, e7500-e7500. PubMed  Europe PubMed DOI  K
  39. Tarasuk,M., Vichasri Grams,S., Viyanant,V. and Grams,R.
    Type I cystatin (stefin) is a major component of Fasciola gigantica excretion/secretion product
    Mol Biochem Parasitol167, 60-71. PubMed  Europe PubMed DOI
  40. Zhou,J., Liao,M., Ueda,M., Gong,H., Xuan,X. and Fujisaki,K.
    Characterization of an intracellular cystatin homolog from the tick Haemaphysalis longicornis
    Vet Parasitol160, 180-183. PubMed  Europe PubMed DOI
  41. 2006
  42. [YEAR:12-6-2006]Lima,C.A., Sasaki,S.D. and Tanaka,A.S.
    Bmcystatin, a cysteine proteinase inhibitor characterized from the tick Boophilus microplus
    Biochem Biophys Res Commun347, 44-50. PubMed  Europe PubMed DOI
  43. 2004
  44. El-Halawany,M.S., Ohkouchi,S., Shibata,H., Hitomi,K. and Maki,M.
    Identification of cysteine protease inhibitors that belong to cystatin family 1 in the cellular slime mold Dictyostelium discoideum
    Biol Chem385, 547-550. PubMed  Europe PubMed DOI
  45. 2001
  46. Ichikawa,K., Vailes,L.D., Pom's,A. and Chapman,M.D.
    Molecular cloning, expression and modelling of cat allergen, cystatin (Fel d 3), a cysteine protease inhibitor
    Clin Exp Allergy31, 1279-1286. PubMed  Europe PubMed DOI
  47. 1996
  48. Lenarcic,B., Krizaj,I., Zunec,P. and Turk,V.
    Differences in specificity for the interactions of stefins A, B and D with cysteine proteinases
    FEBS Lett395, 113-118. PubMed  Europe PubMed DOI