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Literature for inhibitor I25.009: cystatin SA

Summary Gene structure Alignment Sequences Sequence features Distribution Literature Inhibits

(Topics flags: K Knockout, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Garza Martinez,F.E., Kanda,M., Sato,Y., Zhu,H., Bayasgalan,T., Hamrah,M.H., Shimizu,D., Tanaka,H., Umeda,S., Hattori,N., Hayashi,M., Tanaka,C., Nakayama,G. and Kodera,Y.
    The role of CST2 in the pathogenesis and prognosis of esophageal squamous cell carcinoma
    Clin Transl Oncol (2025) PubMed  Europe PubMed DOI  K
    2. 2024
  2. Lu,Y., Wang,H., Chen,S., Yang,B., Li,Y. and Li,Y.
    Cystatin SA attenuates gastric cancer cells growth and increases sensitivity to oxaliplatin via PI3K/AKT signaling pathway
    J Cancer Res Clin Oncol (2024) 150, 244-244. PubMed  Europe PubMed DOI  PMC  EPMC
    3. 2023
  3. Ou,R., Lin,C. and Chen,Y.
    CST2 is activated by RUNX1 and promotes pancreatic cancer progression by activating PI3K/AKT pathway
    Arch Biochem Biophys (2023) 747, 109760-109760. PubMed  Europe PubMed DOI  K
    4. 2022
  4. Nocera,A.L., Mueller,S.K., Workman,A.D., Wu,D., McDonnell,K., Sadow,P.M., Amiji,M.M. and Bleier,B.S.
    Cystatin SN is a potent upstream initiator of epithelial-derived type 2 inflammation in chronic rhinosinusitis
    J Allergy Clin Immunol (2022) PubMed  Europe PubMed DOI  K  V
    5. 2020
  5. Zhang,W.P., Wang,Y., Tan,D. and Xing,C.G.
    Cystatin 2 leads to a worse prognosis in patients with gastric cancer
    J Biol Regul Homeost Agents (2020) 34 PubMed  Europe PubMed DOI
    6. 2013
  6. Lindh,E., Brannstrom,J., Jones,P., Wermeling,F., Hassler,S., Betterle,C., Garty,B.Z., Stridsberg,M., Herrmann,B., Karlsson,M.C. and Winqvist,O.
    Autoimmunity and cystatin SA1 deficiency behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome type 1
    J Autoimmun (2013) 42, 1-6. PubMed  Europe PubMed DOI
    7. 2011
  7. Eliyahu,E., Shtraizent,N., He,X., Chen,D., Shalgi,R. and Schuchman,E.H.
    Identification of cystatin SA as a novel inhibitor of acid ceramidase
    J Biol Chem (2011) 286, 35624-35633. PubMed  Europe PubMed DOI
    8. 2006
  8. [YEAR:25-4-2006]Akiba,S., Hayashi,Y., Hakamada,Y., Endo,K., Ara,K., Kawai,S. and Saitoh,E.
    Extracellular production of human cystatin S and cystatin SA by Bacillus subtilis
    Protein Expr Purif (25-4-2006) 49, 203-210. PubMed  Europe PubMed DOI  E
    9. 2004
  9. Kato,T., Ito,T., Imatani,T., Minaguchi,K., Saitoh,E. and Okuda,K.
    Cystatin SA, a cysteine proteinase inhibitor, induces interferon-gamma expression in CD4-positive T cells
    Biol Chem (2004) 385, 419-422. PubMed  Europe PubMed DOI
    10. 2002
  10. Dickinson,D.P., Thiesse,M. and Hicks,M.J.
    Expression of type 2 cystatin genes CST1-CST5 in adult human tissues and the developing submandibular gland
    DNA Cell Biol (2002) 21, 47-65. PubMed  Europe PubMed DOI
    11. 1999
  11. Haga,T. and Minaguchi,K.
    Sequence variations of the CST2 gene related to the polymorphism of salivary cystatin SA
    J Dent Res (1999) 78, 835-839. PubMed  Europe PubMed
    12. 1998
  12. [YEAR:15-4-1998]Saitoh,E., Minaguchi,K. and Ishibashi,O.
    Production and characterization of two variants of human cystatin SA encoded by two alleles at the CST2 locus of the type 2 cystatin gene family
    Arch Biochem Biophys (15-4-1998) 352, 199-206. PubMed  Europe PubMed DOI
    13. 1997
  13. Bell,J.E., Cunningham,E., Belt,C., Featherstone,J.D. and Bell,J.
    Examination of the potential structure of human salivary cystatins based on computer modelling
    Arch Oral Biol (1997) 42, 761-772. PubMed  Europe PubMed DOI
    14. 1994
  14. Shintani,M., Minaguchi,K., Isemura,S., Saitoh,E., Sanada,K. and Semba,T.
    Genetic polymorphisms of the CST2 locus coding for cystatin SA
    Hum Genet (1994) 94, 45-49. PubMed  Europe PubMed DOI
    15. 1991
  15. Isemura,S., Saitoh,E., Sanada,K. and Minakata,K.
    Identification of full-sized forms of salivary (S-type) cystatins (cystatin SN, cystatin SA, cystatin S, and two phosphorylated forms of cystatin S) in human whole saliva and determination of phosphorylation sites of cystatin S
    J Biochem (1991) 110, 648-654. PubMed  Europe PubMed
  16. Lamkin,M.S., Jensen,J.L., Setayesh,M.R., Troxler,R.F. and Oppenheim,F.G.
    Salivary cystatin SA-III, a potential precursor of the acquired enamel pellicle, is phosphorylated at both its amino- and carboxyl-terminal regions
    Arch Biochem Biophys (1991) 288, 664-670. PubMed  Europe PubMed DOI
  17. [YEAR:29-3-1991]Saitoh,E., Isemura,S., Sanada,K. and Ohnishi,K.
    Cystatins of family II are harboring two domains which retain inhibitory activities against the proteinases
    Biochem Biophys Res Commun (29-3-1991) 175, 1070-1075. PubMed  Europe PubMed DOI
    18. 1988
  18. [YEAR:5-7-1988]Al-Hashimi,I., Dickinson,D.P. and Levine,M.J.
    Purification, molecular cloning, and sequencing of salivary cystatin SA-1
    J Biol Chem (5-7-1988) 263, 9381-9387. PubMed  Europe PubMed
    19. 1987
  19. Isemura,S., Saitoh,E. and Sanada,K.
    Characterization and amino acid sequence of a new acidic cysteine proteinase inhibitor (cystatin SA) structurally closely related to cystatin S, from human whole saliva
    J Biochem (1987) 102, 693-704. PubMed  Europe PubMed
  20. Saitoh,E., Kim,H.S., Smithies,O. and Maeda,N.
    Human cysteine-proteinase inhibitors: nucleotide sequence analysis of three members of the cystatin gene family
    Gene (1987) 61, 329-338. PubMed  Europe PubMed
    21. 1984
  21. Minakata,K. and Asano,M.
    New protein inhibitors of cysteine proteinases in human saliva and salivary glands
    Hoppe Seylers Z Physiol Chem (1984) 365, 399-403. PubMed  Europe PubMed

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