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Literature for inhibitor I25.004: cystatin C

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Inhibits

(Topics flags: A Assay, S Structure, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Li,X., Tang,X., Zeng,J., Duan,L., Hou,Z., Li,L., Guo,Y., Chai,C., Liu,J., Wang,Y., Zhu,L.Q., Li,H., Zhang,T., Wang,Y., He,A. and Lu,Y.
    Peripheral cancer attenuates amyloid pathology in Alzheimer's disease via cystatin-c activation of TREM2
    Cell (2026) 189, 853-871. PubMed  Europe PubMed DOI
    2. 2025
  2. Bhuiya,J., Shibly,A.Z., Sheikh,A.M., Tabassum,S., Abdullah,F.B., Fahmida,J., Tamegai,H., Aritake,S., Yano,S. and Nagai,A.
    Deposition of aggregated cystatin C-amyloid-beta complexes and reduced cathepsin B activity modulate cerebral amyloid angiopathy pathogenesis
    J Neuropathol Exp Neurol (2025) PubMed  Europe PubMed DOI
  3. Dabravolski,S.A., Elizova,N.V., Korchagina,E.R., Maltseva,O.N., Pavshintsev,V.V. and Orekhov,A.N.
    Cystatin C in atherosclerotic cardiovascular disease
    Clin Chim Acta (2025) 580, 120721-120721. PubMed  Europe PubMed DOI
  4. El-Raheem,H.A., Rudayni,H.A., Allam,A.A., Mahmoud,R., Youssef,A.F.A., Ramadan,O. and Alahmad,W.
    Gold nanoparticle electrochemical biosensors for cystatin C
    Clin Chim Acta (2025) 579, 120683-120683. PubMed  Europe PubMed DOI
  5. Li,M., Xie,H. and Du,X.
    Cystatin C 3 (CST3) drives pathological progression in recurrent spontaneous abortion
    J Reprod Immunol (2025) 168, 104441-104441. PubMed  Europe PubMed DOI
  6. Modenbach,J.M., Moller,C., Asgarbeik,S., Geist,N., Rimkus,N., Dorr,M., Wolfgramm,H., Steil,L., Susemihl,A., Graf,L., Schmoker,O., Bottcher,D., Hammer,E., Glaubitz,J., Lammers,M., Delcea,M., Volker,U., Aghdassi,A.A., Lerch,M.M., Weiss,F.U., Bornscheuer,U.T. and Sendler,M.
    Biochemical analyses of cystatin-C dimers and cathepsin-B reveals a trypsin-driven feedback mechanism in acute pancreatitis
    Nat Commun (2025) 16, 1702-1702. PubMed  Europe PubMed DOI  PMC  EPMC
  7. Paliwal,P., Desai,D. and Datta,M.
    Novel selective and sensitive electrochemical sensor for detection of ovarian cancer biomarker, Cathepsin L
    Bioelectrochemistry (2025) 162, 108856-108856. PubMed  Europe PubMed DOI
  8. Raveendran,J., Gangadharan,D., Bayry,J. and Rasheed,P.A.
    Emerging trends in the cystatin C sensing technologies: towards better chronic kidney disease management
    RSC Adv (2025) 15, 4926-4944. PubMed  Europe PubMed DOI  PMC  EPMC  V
  9. Zyla,A., Zhukov,I., Taube,M., Wojciechowska,D., Wolak,J., Jurczak,P., Czaplewska,P., Szymanska,A., Martel,A. and Kozak,M.
    Comprehensive Analysis of Interactions between Human Serum Albumin and Human Cystatin C - Two Proteins Present in Body Fluids
    ACS Omega (2025) 10, 36299-36309. PubMed  Europe PubMed DOI  PMC  EPMC
    10. 2024
  10. Bikkarolla,S.K., Venkatesan,K., Revathy,Y.R., Parameswaran,S., Krishnakumar,S. and Dendukuri,D.
    The Quantitative Detection of Cystatin-C in Patient Samples Using a Colorimetric Lateral Flow Immunoassay
    Biosensors (Basel) (2024) 14 PubMed  Europe PubMed DOI  PMC  EPMC
  11. Blancas-Luciano,B.E., Becker-Fauser,I., Zamora-Chimal,J., Jimenez-Garcia,L., Lara-Martinez,R., Perez-Torres,A., Gonzalez Del Pliego,M., Aguirre-Benitez,E.L. and Fernandez-Presas,A.M.
    Cystatin C: immunoregulation role in macrophages infected with Porphyromonas gingivalis
    PeerJ (2024) 12, e17252-e17252. PubMed  Europe PubMed DOI  PMC  EPMC
  12. Du,Y. and Li,Z.
    Cystatin C alleviates unconjugated bilirubin-induced neurotoxicity by promoting bilirubin clearance from neurocytes via exosomes, dependent on hepatocyte UGT1A1 activity
    Transl Neurosci (2024) 15, 20220357-20220357. PubMed  Europe PubMed DOI  PMC  EPMC
  13. Jurczak,P., Zhukov,I., Orlikowska,M., Czaplewska,P. and Sikorska,E.
    Monitoring the interactions between POPG phospholipid bilayer and amyloid-forming protein human cystatin C. Does the bilayer influence the oligomeric state and structure of the protein?
    Biochim Biophys Acta Biomembr (2024) 1866, 184285-184285. PubMed  Europe PubMed DOI
  14. Liu,C., Levey,A.S. and Ballew,S.H.
    Serum creatinine and serum cystatin C as an index of muscle mass in adults
    Curr Opin Nephrol Hypertens (2024) 33, 557-565. PubMed  Europe PubMed DOI  V
  15. Niedzialkowski,P., Jurczak,P., Orlikowska,M., Wcislo,A., Ryl,J., Ossowski,T. and Czaplewska,P.
    Phospholipid-functionalized gold electrode for cellular membrane interface studies - interactions between DMPC bilayer and human cystatin C
    Biochim Biophys Acta Biomembr (2024) 1866, 184266-184266. PubMed  Europe PubMed DOI
  16. Stehle,T. and Delanaye,P.
    Which is the best glomerular filtration marker: Creatinine, cystatin C or both?
    Eur J Clin Invest (2024) , e14278-e14278. PubMed  Europe PubMed DOI  V
  17. Yang,H., Han,R.Y., Gong,R.W., Zhang,Y.J., Yang,S.S., Xu,G.Z. and Liu,W.
    CST3 alleviates retinal vascular leakage by regulating the Rap1 signaling pathway
    Exp Eye Res (2024) 247, 110042-110042. PubMed  Europe PubMed DOI
  18. Zygowska,J., Orlikowska,M., Zhukov,I., Bal,W. and Szymanska,A.
    Copper interaction with cystatin C: effects on protein structure and oligomerization
    FEBS J (2024) 291, 1974-1991. PubMed  Europe PubMed DOI
    19. 2023
  19. Adingwupu,O.M., Barbosa,E.R., Palevsky,P.M., Vassalotti,J.A., Levey,A.S. and Inker,L.A.
    Cystatin C as a GFR Estimation Marker in Acute and Chronic Illness: A Systematic Review
    Kidney Med (2023) 5, 100727-100727. PubMed  Europe PubMed DOI  PMC  EPMC  V
  20. Chen,J., Shen,J., Pan,Y., Jing,J., Wang,Y., Wei,T. and Lyu,L.
    Association of serum cystatin C level with coronary atherosclerotic plaque burden: a comprehensive analysis of observational studies and genetic study
    BMC Cardiovasc Disord (2023) 23, 499-499. PubMed  Europe PubMed DOI  PMC  EPMC
  21. He,J., Liang,P., Wang,T. and Han,S.
    A magnetic solid phase chemiluminescent immunoassay for quantification of Cystatin C in human serum
    BMC Biotechnol (2023) 23, 45-45. PubMed  Europe PubMed DOI  PMC  EPMC
  22. Wasyanto,T., Yasa,A. and Yudhistira,Y.
    Cystatin C as a Predictor of Major Adverse Cardiovascular Event in Patients with Acute Myocardial Infarction Without Cardiogenic Shock and Renal Impairment After Coronary Intervention
    Int J Gen Med (2023) 16, 2219-2227. PubMed  Europe PubMed DOI  PMC  EPMC
  23. Zyla,A., Martel,A., Jurczak,P., Molinski,A., Szymanska,A. and Kozak,M.
    Human cystatin C induces the disaggregation process of selected amyloid beta peptides: a structural and kinetic view
    Sci Rep (2023) 13, 20833-20833. PubMed  Europe PubMed DOI  PMC  EPMC
    24. 2022
  24. Denamur,S., Chazeirat,T., Maszota-Zieleniak,M., Vives,R.R., Saidi,A., Zhang,F., Linhardt,R.J., Labarthe,F., Samsonov,S.A., Lalmanach,G. and Lecaille,F.
    Binding of heparan sulfate to human cystatin C modulates inhibition of cathepsin L: Putative consequences in mucopolysaccharidosis
    Carbohydr Polym (2022) 293, 119734-119734. PubMed  Europe PubMed DOI
  25. Ding,L., Liu,Z. and Wang,J.
    Role of cystatin C in urogenital malignancy
    Front Endocrinol (Lausanne) (2022) 13, 1082871-1082871. PubMed  Europe PubMed DOI  PMC  EPMC  V
    26. 2021
  26. Biasizzo,M., Trstenjak-Prebanda,M., Dolinar,K., Pirkmajer,S., Zavrsnik,J., Turk,B. and Kopitar-Jerala,N.
    Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice
    Cells (2021) 10 PubMed  Europe PubMed DOI  PMC  EPMC
  27. Christopher,J.R., Ponnaiyan,D., Parthasarathy,H. and Tadepalli,A.
    Association of CST3 Gene with Its Protein: Cystatin C in Health and Severe Periodontal Disease
    Genet Test Mol Biomarkers (2021) 25, 405-410. PubMed  Europe PubMed DOI
  28. Hayn,M., Blotz,A., Rodriguez,A., Vidal,S., Preising,N., Standker,L., Wiese,S., Sturzel,C.M., Harms,M., Gross,R., Jung,C., Kiene,M., Jacob,T., Pohlmann,S., Forssmann,W.G., Munch,J., Sparrer,K.M.J., Seuwen,K., Hahn,B.H. and Kirchhoff,F.
    Natural cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling
    Proc Natl Acad Sci U S A (2021) 118 PubMed  Europe PubMed DOI  PMC  EPMC
  29. March,M.E., Gutierrez-Uzquiza,A., Snorradottir,A.O., Matsuoka,L.S., Balvis,N.F., Gestsson,T., Nguyen,K., Sleiman,P.M.A., Kao,C., Isaksson,H.J., Bragason,B.T., Olafsson,E., Palsdottir,A. and Hakonarson,H.
    NAC blocks Cystatin C amyloid complex aggregation in a cell system and in skin of HCCAA patients
    Nat Commun (2021) 12, 1827-1827. PubMed  Europe PubMed DOI  PMC  EPMC
  30. Mommaerts,K., Willemse,E.A.J., Marchese,M., Larue,C., van der Flier,W.M., Betsou,F. and Teunissen,C.E.
    A Cystatin C Cleavage ELISA Assay as a Quality Control Tool for Determining Sub-Optimal Storage Conditions of Cerebrospinal Fluid Samples in Alzheimer's Disease Research
    J Alzheimers Dis (2021) PubMed  Europe PubMed DOI
  31. Sawada,S.
    Cystatin C as a Promising Biomarker of Atherosclerotic Plaque
    J Atheroscler Thromb (2021) 28, 474-476. PubMed  Europe PubMed DOI
  32. Sheikh,A.M., Wada,Y., Tabassum,S., Inagaki,S., Mitaki,S., Yano,S. and Nagai,A.
    Aggregation of Cystatin C Changes Its Inhibitory Functions on Protease Activities and Amyloid beta Fibril Formation
    Int J Mol Sci (2021) 22 PubMed  Europe PubMed DOI  PMC  EPMC
  33. Taha,M.M., Shahy,E.M., Mahdy-Abdallah,H., Ibrahim,K.S. and El Tahlawy,E.M.
    Evaluation of the effect of serum cystatin-C and ACE I/D and ACE G2350A polymorphisms on kidney function among hypertensive sewage workers
    Environ Sci Pollut Res Int (2021) 28, 1619-1626. PubMed  Europe PubMed DOI
  34. Tavares,J., Santos,J., Silva,F., Oliveira,J., Malheiro,J., Campos,A. and Cabrita,A.
    Association between severe chronic kidney disease defined by cystatin-c and creatinine and clinical outcomes in an elderly population - an observational study
    J Bras Nefrol (2021) 43, 165-172. PubMed  Europe PubMed DOI
  35. Wallin,H., Hunaiti,S. and Abrahamson,M.
    Externally added cystatin C reduces growth of A375 melanoma cells by increasing cell cycle time
    FEBS Open Bio (2021) PubMed  Europe PubMed DOI
  36. Wang,B., Yu,X.A., Yin,G., Wang,J., Jin,Y. and Wang,T.
    Developing a novel and simple biosensor for Cystatin C as a fascinating marker of glomerular filtration rate with DNase I-aided recycling amplification strategy
    J Pharm Biomed Anal (2021) 203, 114230-114230. PubMed  Europe PubMed DOI
  37. Zhang,X., Liu,X., Su,G., Li,M., Liu,J., Wang,C. and Xu,D.
    pH-dependent and dynamic interactions of cystatin C with heparan sulfate
    Commun Biol (2021) 4, 198-198. PubMed  Europe PubMed DOI  PMC  EPMC
    38. 2020
  38. Asmamaw,T., Genet,S., Menon,M., Tarekegn,G., Chekol,E., Geto,Z., Lejisa,T., Habtu,W., Getahun,T. and Tolcha,Y.
    Early Detection of Renal Impairment Among Patients with Type 2 Diabetes Mellitus Through Evaluation of Serum Cystatin C in Comparison with Serum Creatinine Levels: A Cross-Sectional Study
    Diabetes Metab Syndr Obes (2020) 13, 4727-4735. PubMed  Europe PubMed DOI  PMC  EPMC
  39. Balczon,R., Morrow,K.A., Leavesley,S., Francis,C.M., Stevens,T.C., Agwaramgbo,E., Williams,C., Stevens,R.P., Langham,G., Voth,S., Cioffi,E.A., Weintraub,S.E. and Stevens,T.
    Cystatin C regulates the cytotoxicity of infection-induced endothelial-derived beta-amyloid
    FEBS Open Bio (2020) PubMed  Europe PubMed DOI
  40. Can,N., Ozsoy,E., Kobat,S.G., Yusufoglu,E., Ilhan,N. and Demir,T.
    Serum Cystatin C Concentrations in Patients with Graves' Ophthalmopathy
    Korean J Ophthalmol (2020) 34, 398-403. PubMed  Europe PubMed DOI  PMC  EPMC
  41. Chang,Z., Zou,H., Xie,Z., Deng,B., Que,R., Huang,Z., Weng,G., Wu,Z., Pan,Y., Wang,Y., Li,M., Xie,H., Zhu,S., Xiong,L., Ct Mok,V., Jin,K., Yenari,M.A., Wei,X. and Wang,Q.
    Cystatin C is a potential predictor of unfavorable outcomes for cerebral ischemia with intravenous tissue plasminogen activator treatment: A multicenter prospective nested case-control study
    Eur J Neurol (2020) PubMed  Europe PubMed DOI
  42. Chazot,R., Botelho-Nevers,E., Mariat,C., Fresard,A., Cavalier,E., Lucht,F., Delanaye,P., Maillard,N. and Gagneux-Brunon,A.
    Cystatin C and urine albumin-to-creatinine ratio predict 5-year mortality and cardiovascular events in People Living with HIV independently of measured GFR
    J Infect Dis (2020) PubMed  Europe PubMed DOI
  43. Chen,D., Cao,C., Jiang,L., Tan,Y., Yuan,H., Pan,B., Ma,M., Zhang,H. and Wan,X.
    Serum cystatin C: A potential predictor for hospital-acquired acute kidney injury in patients with acute exacerbation of COPD
    Chron Respir Dis (2020) 17, 1479973120940677-1479973120940677. PubMed  Europe PubMed DOI  PMC  EPMC
  44. Chen,S., Liu,L., Zhang,W., Sun,L., Wang,F., Zhao,Y., Liu,S., Zhao,L. and Xu,Y.
    Suppressed dendritic cell functions by cystatin C lead to compromised immunity in vivo
    Cell Immunol (2020) 349, 104049-104049. PubMed  Europe PubMed DOI
  45. Chrabaszczewska,M., Sieradzan,A.K., Rodziewicz-Motowidlo,S., Grubb,A., Dobson,C.M., Kumita,J.R. and Kozak,M.
    Structural Characterization of Covalently Stabilized Human Cystatin C Oligomers
    Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  PMC  EPMC
  46. Chuma,M., Kondo,M., Zamami,Y., Takechi,K., Goda,M., Okada,N., Shibata,A., Asada,M., Oto,J., Yanagawa,H. and Ishizawa,K.
    Successful Vancomycin Dose Adjustment in a Sepsis patient with Bacterial Meningitis Using Cystatin C
    Acta Med Okayama (2020) 74, 365-370. PubMed  Europe PubMed DOI
  47. Ciin,M.N., Proungvitaya,T., Limpaiboon,T., Roytrakul,S., Cha'on,U., Tummanatsakun,D. and Proungvitaya,S.
    Serum Cystatin C as a Potential Marker for Glomerular Filtration Rate in Patients with Cholangiocarcinoma
    Int J Hematol Oncol Stem Cell Res (2020) 14, 157-166. PubMed  Europe PubMed DOI  PMC  EPMC
  48. Cui,Z., Cao,G., Wang,Y., Ma,Q., Wang,C., Xu,Y., Sun,H. and Ma,Y.
    Effects of Cystatin C on Cognitive Impairment in Older Chinese Adults
    Am J Alzheimers Dis Other Demen (2020) 35, 1533317520965101-1533317520965101. PubMed  Europe PubMed DOI
  49. Dekker,M., Waissi,F., van Bennekom,J., Silvis,M.J.M., Timmerman,N., Schoneveld,A.H., Grobbee,D.E., de Winter,R.J., Mosterd,A., Timmers,L. and de Kleijn,D.P.V.
    Extracellular Vesicle cystatin c is associated with unstable angina in troponin negative patients with acute chest pain
    PLoS ONE (2020) 15, e0237036-e0237036. PubMed  Europe PubMed DOI  PMC  EPMC
  50. Downes,K.J., Zane,N.R. and Zuppa,A.F.
    Effect of Cystatin C on Vancomycin Clearance Estimation in Critically Ill Children Using a Population Pharmacokinetic Modeling Approach
    Ther Drug Monit (2020) PubMed  Europe PubMed DOI
  51. Ebert,N. and Shlipak,M.G.
    Cystatin C is ready for clinical use
    Curr Opin Nephrol Hypertens (2020) 29, 591-598. PubMed  Europe PubMed DOI  V
  52. Eiamcharoenying,J., Kulvichit,W., Lumlertgul,N., Chaiwatanarat,T., Peerapornratana,S. and Srisawat,N.
    The role of serum cystatin C in estimation of renal function in survivors of critical illness
    J Crit Care (2020) 59, 201-206. PubMed  Europe PubMed DOI
  53. Fernando,S. and Polkinghorne,K.R.
    Cystatin C: not just a marker of kidney function
    J Bras Nefrol (2020) 42, 6-7. PubMed  Europe PubMed DOI
  54. Fu,X., Tian,Z., Wen,S., Sun,H., Thapa,S., Xiong,H., Liu,H., Li,L. and Yu,S.
    A new index based on serum creatinine and cystatin C is useful for assessing sarcopenia in patients with advanced cancer
    Nutrition (2020) , 111032-111032. PubMed  Europe PubMed DOI
  55. Grasselli,C., Barbati,A., Cesarini,L., Pellegrino,R. and Di Renzo,G.C.
    The validation of immunoblot SDS-PAGE as a qualitative and quantitative method for the determination of urinary Cystatin C in neonates
    Clin Biochem (2020) PubMed  Europe PubMed DOI
  56. Greco,M., Foti,D.P., Aversa,A., Fuiano,G., Brunetti,A. and Simeoni,M.
    Cystatin C, a Controversial Biomarker in Hypothyroid Patients under Levothyroxine Therapy: THYRenal, a Pilot Cohort Observational Study
    J Clin Med (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
  57. Hansson,M., Gustafsson,R., Jacquet,C., Chebaane,N., Satchell,S., Thunberg,T., Ahlm,C. and Fors Connolly,A.M.
    Cystatin C and alpha-1-Microglobulin Predict Severe Acute Kidney Injury in Patients with Hemorrhagic Fever with Renal Syndrome
    Pathogens (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
  58. Hendrickson,C.M., Kwong,Y.D., Belzer,A.G., Shlipak,M.G., Matthay,M.A. and Liu,K.D.
    Higher plasma cystatin C is associated with mortality after acute respiratory distress syndrome: findings from a Fluid and Catheter Treatment Trial (FACTT) substudy
    Crit Care (2020) 24, 416-416. PubMed  Europe PubMed DOI  PMC  EPMC
  59. Hirai,K., Tanaka,A., Homma,T., Goto,Y., Akimoto,K., Uno,T., Yoshitaka,U., Miyata,Y., Inoue,H., Ohta,S., Suzuki,S. and Sagara,H.
    Serum creatinine/cystatin C ratio as a surrogate marker for sarcopenia in patients with chronic obstructive pulmonary disease
    Clin Nutr (2020) PubMed  Europe PubMed DOI
  60. Hoghooghi,V., Palmer,A.L., Frederick,A., Jiang,Y., Merkens,J.E., Balakrishnan,A., Finlay,T.M., Grubb,A., Levy,E., Gordon,P., Jirik,F.R., Nguyen,M.D., Schuurmans,C., Visser,F., Dunn,S.E. and Ousman,S.S.
    Cystatin C Plays a Sex-Dependent Detrimental Role in Experimental Autoimmune Encephalomyelitis
    Cell Rep (2020) 33, 108236-108236. PubMed  Europe PubMed DOI
  61. Iacomelli,I., Giordano,A., Rivasi,G., Rafanelli,M., Tortu,V., Cartei,A., Rostagno,C., Di Bari,M., Marchionni,N., Mossello,E. and Ungar,A.
    Low Creatinine Potentially Overestimates Glomerular Filtration Rate in Older Fracture Patients: A Plea for an Extensive Use of Cystatin C?
    Eur J Intern Med (2020) PubMed  Europe PubMed DOI
  62. Indacochea,A., Guerrero,S., Ure Ntildea,M., Araujo,F., Coll,O., LLeonart,M.E. and Gebauer,F.
    Cold-inducible RNA binding protein promotes breast cancer cell malignancy by regulating Cystatin C levels
    RNA (2020) PubMed  Europe PubMed DOI
  63. Ivey-Miranda,J.B., Inker,L.A., Griffin,M., Rao,V., Maulion,C., Turner,J.M., Wilson,F.P., Tang,W.W., Levey,A.S. and Testani,J.M.
    Cystatin C and muscle mass in patients with heart failure
    J Card Fail (2020) PubMed  Europe PubMed DOI
  64. Jahic,A., Znidaric,M.T., Pintar,S., Berbic,S. and Zerovnik,E.
    The effect of three polyphenols and some other anti-oxidant substances on amyloid fibril formation by human cystatin C
    Neurochem Int (2020) , 104806-104806. PubMed  Europe PubMed DOI  I
  65. Jiang,Y., Zhang,J., Zhang,C., Hong,L., Jiang,Y., Lu,L., Huang,H. and Guo,D.
    The role of cystatin C as a proteasome inhibitor in multiple myeloma
    Hematology (2020) 25, 457-463. PubMed  Europe PubMed DOI  V
  66. Jin,S., Xu,J., Shen,G. and Gu,P.
    Predictive value of circulating cystatin C level in patients with acute coronary syndrome: a meta-analysis
    Scand J Clin Lab Invest (2020) , 1-7. PubMed  Europe PubMed DOI
  67. Jung,C.Y., Joo,Y.S., Kim,H.W., Han,S.H., Yoo,T.H., Kang,S.W. and Park,J.T.
    Creatinine-Cystatin C Ratio and Mortality in Patients Receiving Intensive Care and Continuous Kidney Replacement Therapy: A Retrospective Cohort Study
    Am J Kidney Dis (2020) PubMed  Europe PubMed DOI
  68. Jurczak,P., Sikorska,E., Czaplewska,P., Rodziewicz-Motowidlo,S., Zhukov,I. and Szymanska,A.
    The Influence of the Mixed DPC:SDS Micelle on the Structure and Oligomerization Process of the Human Cystatin C
    Membranes (Basel) (2020) 11 PubMed  Europe PubMed DOI  PMC  EPMC
  69. Jurczak,P., Szutkowski,K., Lach,S., Jurga,S., Czaplewska,P., Szymanska,A. and Zhukov,I.
    DMPC Phospholipid Bilayer as a Potential Interface for Human Cystatin C Oligomerization: Analysis of Protein-Liposome Interactions Using NMR Spectroscopy
    Membranes (Basel) (2020) 11 PubMed  Europe PubMed DOI  PMC  EPMC
  70. Karakus,A., Tutuncu,A., Camci,S., Uguz,B., Ozmen,G., Ari,H. and Demir,M.
    A New Perspective for Isolated Coronary Artery Ectasia: Cystatin C
    Cureus (2020) 12, e11053-e11053. PubMed  Europe PubMed DOI  PMC  EPMC
  71. Kim,M.C., Kim,S.O., Kim,S.H., Shin,J.H., Choi,S.H., Chung,J.W. and Hwang,J.H.
    Efficacy and Safety of Cystatin C-Guided Renal Dose Adjustment of Cefepime Treatment in Hospitalized Patients with Pneumonia
    J Clin Med (2020) 9 PubMed  Europe PubMed DOI
  72. Klisic,A., Kavaric,N. and Ninic,A.
    Serum cystatin C levels are associated with triglycerides/high-density lipoprotein cholesterol ratio in adolescent girls ages between 16-19 years old
    Eur Rev Med Pharmacol Sci (2020) 24, 10680-10686. PubMed  Europe PubMed DOI
  73. Koyama,H. and Kadoya,M.
    Serum cystatin C level in chronic hypercortisolism
    Endocr J (2020) PubMed  Europe PubMed DOI
  74. Li,B., Zhu,C., Dong,L., Qin,J., Xiang,W., Davidson,A.J., Feng,S., Wang,Y., Shen,X., Weng,C., Wang,C., Zhu,T., Teng,L., Wang,J., Englert,C., Chen,J. and Jiang,H.
    ADAM10 mediates ectopic proximal tubule development and renal fibrosis through Notch signalling
    J Pathol (2020) PubMed  Europe PubMed DOI
  75. Li,Y., Yang,S., Peng,D., Zhu,H.M., Li,B.Y., Yang,X., Sun,X.L. and Zhang,M.
    Predictive value of serum cystatin C for risk of mortality in severe and critically ill patients with COVID-19
    World J Clin Cases (2020) 8, 4726-4734. PubMed  Europe PubMed DOI  PMC  EPMC
  76. Liang,S., Shi,M., Bai,Y., Deng,Y., Fang,M., Li,J., Wu,Y., Peng,W., Hou,Y., Fang,H., Zhang,H. and Chen,C.
    The effect of glucocorticoids on serum cystatin C in identifying acute kidney injury: a propensity-matched cohort study
    BMC Nephrol (2020) 21, 519-519. PubMed  Europe PubMed DOI  PMC  EPMC
  77. Liu,C.S., Li,C.I., Guo,Y.C., Lin,C.H., Lin,W.Y., Liu,C.H., Wang,M.C., Yang,C.W., Yang,S.Y., Li,T.C. and Lin,C.C.
    Independent associations of urinary albumin-to-creatinine ratio and serum cystatin C with carotid intima-media thickness in community-living Taiwanese adults
    BMC Nephrol (2020) 21, 454-454. PubMed  Europe PubMed DOI  PMC  EPMC
  78. Liu,H., Qian,S., Zhong,C., Wang,A., Peng,Y., Peng,H., Xu,T., Bu,X., Xu,T., Geng,D. and Zhang,Y.
    Predictive Value of Cystatin C for Stroke Recurrence in Patients With Acute Ischemic Stroke
    Circ J (2020) PubMed  Europe PubMed DOI
  79. Lucas,G.M., Atta,M.G., Zook,K., Vaidya,D., Tao,X., Maier,P. and Schwartz,G.J.
    Cross-sectional and longitudinal performance of creatinine- and cystatin C-based estimating equations relative to exogenously measured glomerular filtration rate in HIV-positive and HIV-negative persons
    J Acquir Immune Defic Syndr (2020) PubMed  Europe PubMed DOI
  80. Ma,L., Dai,W., Lin,Y., Zhang,Z., Pan,Y., Han,H., Jia,H., Peng,J., Zhao,J. and Xu,L.
    Leukocyte Rho kinase activity and serum cystatin C affect cardiovascular events in acute coronary syndrome
    Medicine (Baltimore) (2020) 99, e20060-e20060. PubMed  Europe PubMed DOI  PMC  EPMC
  81. Markos,J.R., Schaepe,K.S., Teaford,H.R., Rule,A.D., Kashani,K.B., Lieske,J.C. and Barreto,E.F.
    Clinician perspectives on inpatient cystatin C utilization: A qualitative case study at Mayo Clinic
    PLoS ONE (2020) 15, e0243618-e0243618. PubMed  Europe PubMed DOI  PMC  EPMC
  82. Maszota-Zieleniak,M., Jurczak,P., Orlikowska,M., Zhukov,I., Borek,D., Otwinowski,Z., Skowron,P., Pietralik,Z., Kozak,M., Szymanska,A. and Rodziewicz-Motowidlo,S.
    NMR and crystallographic structural studies of the extremely stable monomeric variant of human cystatin C with single amino acid substitution
    FEBS J (2020) 287, 361-376. PubMed  Europe PubMed DOI  S
  83. Mcclean,M., Buzkova,P., Budoff,M., Estrella,M., Freiberg,M., Hodis,H.N., Palella,F., Shikuma,C., Post,W.S. and Gupta,S.
    Cystatin C based estimation of glomerular filtration rate and association with atherosclerosis imaging markers in people living with HIV
    J Acquir Immune Defic Syndr (2020) PubMed  Europe PubMed DOI
  84. Miyagawa,Y., Akabane,R., Ogawa,M., Nagakawa,M., Miyakawa,H. and Takemura,N.
    Serum cystatin C concentration can be used to evaluate glomerular filtration rate in small dogs
    J Vet Med Sci (2020) PubMed  Europe PubMed DOI
  85. Mohd Tahir,N.A., Mohd Saffian,S., Islahudin,F.H., Abdul Gafor,A.H., Othman,H., Abdul Manan,H. and Makmor-Bakry,M.
    Effects of CST3 gene G73A polymorphism on cystatin C in a prospective multiethnic cohort study
    Nephron (2020) 144, 204-212. PubMed  Europe PubMed DOI  M
  86. Moore,R.M., Katri,R., Kumar,D., Mansour,J.M., Mercer,B. and Moore,J.J.
    alpha-Lipoic acid blocks the GMCSF induced protease/protease inhibitor spectrum associated with fetal membrane weakening in-vitro
    Placenta (2020) 97, 79-88. PubMed  Europe PubMed DOI
  87. Morizawa,Y., Satoh,H., Iwasa,S., Sato,A., Aoki,Y. and Hamada,R.
    Clinical Accuracy of Average Creatinine and Cystatin-C-Based Estimated GFR in Japanese Living Renal Transplantation Donors
    Transplant Proc (2020) PubMed  Europe PubMed DOI
  88. Nishimura,Y., Honda,K., Yuzaki,M., Tajima,K., Nakamura,R., Nakanishi,Y., Kaneko,M., Agematsu,K. and Nagashima,M.
    Serum Cystatin C Level as a Biomarker of Aortic Plaque in Patients with an Aortic Arch Aneurysm
    J Atheroscler Thromb (2020) PubMed  Europe PubMed DOI
  89. Omaygenc,M.O., Ozcan,O.U., Cakal,B. and Karaca,O.
    Cystatin C and uncontrolled hypertension
    Anatol J Cardiol (2020) 24, 309-315. PubMed  Europe PubMed DOI
  90. Patel,M.L., Shyam,R., Bharti,H., Sachan,R., Gupta,K.K. and Parihar,A.
    Evaluation of Serum Cystatin C as an Early Biomarker of Acute Kidney Injury in Patients with Acute Pancreatitis
    Indian J Crit Care Med (2020) 24, 777-782. PubMed  Europe PubMed DOI  PMC  EPMC
  91. Potok,O.A., Ix,J.H., Shlipak,M.G., Phil,D., Hawfield,A.T., Rocco,M.V., Ambrosius,W.T., Cho,M.E., Pajewski,N.M., Rastogi,A. and Rifkin,D.E.
    The Difference Between Cystatin C- and Creatinine-Based Estimated GFR and Associations With Frailty and Adverse Outcomes: A Cohort Analysis of the Systolic Blood Pressure Intervention Trial (SPRINT)
    Am J Kidney Dis (2020) PubMed  Europe PubMed DOI
  92. Puttaswamy,S.V., Lubarsky,G.V., Kelsey,C., Zhang,X., Finlay,D., McLaughlin,J.A. and Bhalla,N.
    Nanophotonic-Carbohydrate Lab-on-a-Microneedle for Rapid Detection of Human Cystatin C in Finger-Prick Blood
    ACS Nano (2020) PubMed  Europe PubMed DOI
  93. Qin,Q., Yang,M., Ke,W., Zhao,J. and Ding,H.
    Serum cystatin C is closely associated with euthyroid Hashimoto's thyroiditis in adult female Chinese patients
    J Int Med Res (2020) 48, 300060520952973-300060520952973. PubMed  Europe PubMed DOI  PMC  EPMC
  94. Renganathan,A., Warner,B.B., Tarr,P.I. and Dharnidharka,V.R.
    The progression of serum cystatin C concentrations within the first month of life after preterm birth-a worldwide systematic review
    Pediatr Nephrol (2020) PubMed  Europe PubMed DOI
  95. Rothenbacher,D., Rehm,M., Iacoviello,L., Costanzo,S., Tunstall-Pedoe,H., Belch,J.J.F., Soderberg,S., Hultdin,J., Salomaa,V., Jousilahti,P., Linneberg,A., Sans,S., Padro,T., Thorand,B., Meisinger,C., Kee,F., McKnight,A.J., Palosaari,T., Kuulasmaa,K., Waldeyer,C., Zeller,T., Blankenberg,S. and Koenig,W.
    Contribution of cystatin C- and creatinine-based definitions of chronic kidney disease to cardiovascular risk assessment in 20 population-based and 3 disease cohorts: the BiomarCaRE project
    BMC Med (2020) 18, 300-300. PubMed  Europe PubMed DOI  PMC  EPMC
  96. Salek,T., Vodicka,M. and Griva,M.
    Cystatin C may be better than creatinine for digoxin dosing in older adults with atrial fibrillation
    J Clin Lab Anal (2020) , e23427-e23427. PubMed  Europe PubMed DOI
  97. Schonermarck,U., Dengler,C., Lean,I. and Waldmann,E.
    Comment on: "Overestimation of glomerular filtration rate calculated from serum creatinine as compared with cystatin C in patients with subclinical hypercortisolism: Hyogo Adrenal Metabolic Registry" by Naka et al
    Endocr J (2020) 67, 889-890. PubMed  Europe PubMed DOI
  98. Shen,Y., Zhang,X., Li,C., Wang,X., Ye,Y., Yuan,J., Gong,H., Zou,Y. and Ge,J.
    Pressure overload promotes cystatin C secretion of cardiomyocytes to regulate the MAPK signaling pathway and mediate cardiac hypertrophy
    Ann Transl Med (2020) 8, 1514-1514. PubMed  Europe PubMed DOI  PMC  EPMC
  99. Siddiqui,S.S.
    Serum Cystatin C in Early Identification of Acute Kidney Injury in Acute Pancreatitis: Is It an Old Wine in a New Bottle?
    Indian J Crit Care Med (2020) 24, 744-745. PubMed  Europe PubMed DOI  PMC  EPMC
  100. Sun,Y., Tao,L., Ma,Y., Yang,S., Zhang,X., Jin,B., Zhang,Z. and Yang,K.
    Development of an Approach of High Sensitive Chemiluminescent Assay for Cystatin C Using a Nanoparticle Carrier
    Front Chem (2020) 8, 802-802. PubMed  Europe PubMed DOI  PMC  EPMC
  101. Sun,Y., Lu,Q., Cheng,B. and Tao,X.
    Prognostic value of cystatin C in patients with acute coronary syndrome: A systematic review and meta-analysis
    Eur J Clin Invest (2020) , e13440-e13440. PubMed  Europe PubMed DOI
  102. Tan,S.J., Cockroft,M., Page-Sharp,M., Arendts,G., Davis,T.M.E., Moore,B.R., Batty,K.T., Salman,S. and Manning,L.
    A population pharmacokinetic study of ceftriaxone in elderly patients using Cystatin C-based estimates of renal function to account for frailty
    Antimicrob Agents Chemother (2020) 64, e00874-20-e00874-20. PubMed  Europe PubMed DOI
  103. Teaford,H.R., Stevens,R.W., Rule,A.D., Mara,K.C., Kashani,K.B., Lieske,J.C., O'Horo,J. and Barreto,E.F.
    Prediction of Vancomycin Levels using Cystatin C in Overweight and Obese Patients: A Retrospective Cohort Study of Hospitalized Patients
    Antimicrob Agents Chemother (2020) 65, e01487-20-e01487-20. PubMed  Europe PubMed DOI
  104. Ulmann,G., Kai,J., Durand,J.P., Neveux,N., Jouinot,A., De Bandt,J.P., Goldwasser,F. and Cynober,L.
    Creatinine-to-cystatin C ratio and bioelectrical impedance analysis for the assessement of low lean body mass in cancer patients: Comparison to L3-computed tomography scan
    Nutrition (2020) 81, 110895-110895. PubMed  Europe PubMed DOI
  105. Verbree-Willemsen,L., Zhang,Y.N., Ibrahim,I., Ooi,S.B.S., Wang,J.W., Mazlan,M.I., Kuan,W.S., Chan,S.P., Peelen,L.M., Grobbee,D.E., Richards,A.M., Lam,C.S.P. and de Kleijn,D.P.V.
    Extracellular vesicle Cystatin C and CD14 are associated with both renal dysfunction and heart failure
    ESC Heart Fail (2020) 7, 2240-2249. PubMed  Europe PubMed DOI
  106. Wang,Y., Jia,Y., Wang,C., Gao,X., Liu,Y. and Yue,B.
    Urinary neutrophil gelatinase-associated lipocalin rapidly decreases in the first week after kidney transplantation
    J Clin Lab Anal (2020) , e23445-e23445. PubMed  Europe PubMed DOI
  107. Xu,X., Qin,L. and Yan,L.
    Changes of expression levels of serum cystatin C and soluble vascular endothelial growth factor receptor 1 in the treatment of patients with glomerulus nephritis
    Exp Ther Med (2020) 20, 1550-1556. PubMed  Europe PubMed DOI  PMC  EPMC
  108. Yang,F., Liu,P., Huang,S., Liu,X., Gao,X., Liu,C., Chen,L. and Chen,Y.
    Serum cystatin C was a marker of poststroke fatigue in hypertensive intracerebral hemorrhage
    Brain Behav (2020) , e01969-e01969. PubMed  Europe PubMed DOI
  109. Yu,G., Sun,X., Li,L., Huang,L., Liu,H., Wang,S., Ren,Z. and Zhang,Y.
    Cystatin C promotes cognitive dysfunction in rats with cerebral microbleeds by inhibiting the ERK/synapsin Ia/Ib pathway
    Exp Ther Med (2020) 19, 2282-2290. PubMed  Europe PubMed DOI  PMC  EPMC
  110. Zhang,Q., Cai,Z., Lin,H., Han,L., Yan,J., Wang,J., Ke,P., Zhuang,J. and Huang,X.
    Expression, purification and identification of isotope-labeled recombinant cystatin C protein in Escheichia coli intended for absolute quantification using isotope dilution mass spectrometry
    Protein Expr Purif (2020) 178, 105785-105785. PubMed  Europe PubMed DOI
  111. Zhang,Y., Zhao,J., He,S. and Cao,X.
    Soluble expression of recombinant human cystatin C and comparison of the Ni column and magnetic bead purification
    Protein J (2020) 39, 85-95. PubMed  Europe PubMed DOI  E
  112. Zheng,H., Liu,H., Hao,A., Zhang,M. and Wang,D.
    Association between serum Cystatin C and renal injury in patients with chronic hepatitis B
    Medicine (Baltimore) (2020) 99, e21551-e21551. PubMed  Europe PubMed DOI
    113. 2019
  113. Chaudhuri,A., Biswas,S. and Chakraborty,S.
    Exploring protein-protein intermolecular recognition between meprin-alpha and endogenous protease regulator cystatin C coupled with pharmacophore elucidation
    J Biomol Struct Dyn (2019) 37, 440-453. PubMed  Europe PubMed DOI
  114. Fang,Z., Feng,Y., Li,Y., Deng,J., Nie,H., Yang,Q., Wang,S., Dong,H. and Xiong,L.
    Neuroprotective autophagic flux induced by hyperbaric oxygen preconditioning is mediated by cystatin C
    Neurosci Bull (2019) 35, 336-346. PubMed  Europe PubMed DOI
  115. Perez-Gonzalez,R., Sahoo,S., Gauthier,S.A., Kim,Y., Li,M., Kumar,A., Pawlik,M., Benussi,L., Ghidoni,R. and Levy,E.
    Neuroprotection mediated by cystatin C-loaded extracellular vesicles
    Sci Rep (2019) 9, 11104-11104. PubMed  Europe PubMed DOI  PMC  EPMC
  116. Rafalik,M., Spodzieja,M., Kolodziejczyk,A.S., Rodziewicz-Motowidlo,S., Szymanska,A., Grubb,A. and Czaplewska,P.
    The identification of discontinuous epitope in the human cystatin C - monoclonal antibody HCC3 complex
    J Proteomics (2019) 191, 58-67. PubMed  Europe PubMed DOI
  117. Taube,M., Pietralik,Z., Szymanska,A., Szutkowski,K., Clemens,D., Grubb,A. and Kozak,M.
    The domain swapping of human cystatin C induced by synchrotron radiation
    Sci Rep (2019) 9, 8548-8548. PubMed  Europe PubMed DOI  PMC  EPMC
  118. Tovar-Anaya,D.O., Vera-Robles,L.I., Vieyra-Eusebio,M.T., Garcia-Gutierrez,P., Reyes-Espinosa,F., Hernandez-Arana,A., Arroyo-Reyna,J.A. and Zubillaga,R.A.
    Stabilized human cystatin C variant L47C/G69C is a better reporter than the wild-type inhibitor for characterizing the thermodynamics of binding to cysteine proteases
    Protein J (2019) 38, 598-607. PubMed  Europe PubMed DOI
  119. Trindade,E.K.G., Silva,B.V.M. and Dutra,R.F.
    A probeless and label-free electrochemical immunosensor for cystatin C detection based on ferrocene functionalized-graphene platform
    Biosens Bioelectron (2019) 138, 111311-111311. PubMed  Europe PubMed DOI  A
  120. Wei,S., Cai,J., Wang,S., Yu,Y., Wei,J., Huang,Y., Huang,X. and Qin,Q.
    Functional characterization of cystatin C in orange-spotted grouper, Epinephelus coioides
    Dev Comp Immunol (2019) 96, 37-46. PubMed  Europe PubMed DOI
  121. Yu,H., Xu,X., Zhang,Q. and Wang,X.
    Molecular characterization, expression and functional analysis of cystatin C in Japanese flounder (Paralichthys olivaceus)
    Fish Shellfish Immunol (2019) 86, 695-701. PubMed  Europe PubMed DOI
  122. Zhang,W., Zi,M., Sun,L., Wang,F., Chen,S., Zhao,Y., Liang,S., Hu,J., Liu,S., Liu,L., Zhan,Y., Lew,A.M. and Xu,Y.
    Cystatin C regulates major histocompatibility complex-II-peptide presentation and extracellular signal-regulated kinase-dependent polarizing cytokine production by bone marrow-derived dendritic cells
    Immunol Cell Biol (2019) 97, 916-930. PubMed  Europe PubMed DOI
  123. Zhou,X., Lu,X., Qin,S., Xu,L., Chong,X., Liu,J., Yan,P., Sun,R., Hurley,I.P., Jones,G.W., Wang,Q. and He,J.
    Is the absence of alpha-helix 2 in the appendant structure region the major contributor to structural instability of human cystatin C?
    J Biomol Struct Dyn (2019) 37, 4522-4527. PubMed  Europe PubMed DOI
    124. 2018
  124. Ilowska,E., Sawicka,J. and Szymanska,A.
    Synthesis and physicochemical studies of amyloidogenic hexapeptides derived from human cystatin C
    J Pept Sci (2018) , e3073-e3073. PubMed  Europe PubMed DOI
    125. 2017
  125. Bargnoux,A.S., Pieroni,L., Cristol,J.P., Kuster,N., Delanaye,P., Carlier,M.C., Fellahi,S., Boutten,A., Lombard,C., Gonzalez-Antuna,A., Delatour,V. and Cavalier,E.
    Multicenter evaluation of cystatin C measurement after assay standardization
    Clin Chem (2017) 63, 833-841. PubMed  Europe PubMed DOI  A
  126. Chen,T. and Xu,W.
    A purification method for tag-free human cystatin C recombinant protein expressed in Escherichia coli
    Prep Biochem Biotechnol (2017) 47, 123-128. PubMed  Europe PubMed DOI  E
  127. Murawska,M., Szymanska,A., Grubb,A. and Kozak,M.
    Overall conformation of covalently stabilized domain-swapped dimer of human cystatin C in solution
    Nucl Instrum Methods Phys Res Sect B (2017) 411, 136-140. DOI  S
  128. Perlenfein,T.J., Mehlhoff,J.D. and Murphy,R.M.
    Insights into the mechanism of cystatin C oligomer and amyloid formation and its interaction with beta-amyloid
    J Biol Chem (2017) 292, 11485-11498. PubMed  Europe PubMed DOI
  129. Shamsi,A. and Bano,B.
    Journey of cystatins from being mere thiol protease inhibitors to at heart of many pathological conditions
    Int J Biol Macromol (2017) 102, 674-693. PubMed  Europe PubMed DOI
  130. Yu,Y., Yang,T., Liu,P., Wang,N., Lu,Y., Huang,Y. and Shen,P.
    [Preparation of monoclonal antibody against cystatin C and establishment of its immunoassay system]
    Wei Sheng Yan Jiu (2017) 46, 628-632. PubMed  Europe PubMed  A
    131. 2016
  131. Chauhan,S. and Tomar,R.S.
    Efficient expression and purification of biologically active human cystatin proteins
    Protein Expr Purif (2016) 118, 10-17. PubMed  Europe PubMed DOI  E
  132. Chong,X., Lu,X., Wang,Y., Chang,A.K., Xu,L., Wang,N., Sun,Y., Jones,G.W., Song,Y., Song,Y.B. and He,J.
    Distinct structural changes in wild-type and amyloidogenic chicken cystatin caused by disruption of C95-C115 disulfide bond
    J Biomol Struct Dyn (2016) 34, 2679-2687. PubMed  Europe PubMed DOI
  133. Damm,T., Spiegel,H., Barth,S., Fischer,R. and Naehring,J.
    development of a competitive cystatin C-specific bioassay suitable for repetitive measurements
    PLoS ONE (2016) 11, e0147177-e0147177. PubMed  Europe PubMed DOI  PMC  EPMC  A
  134. Evans,T.I., Joo,N.S., Keiser,N.W., Yan,Z., Tyler,S.R., Xie,W., Zhang,Y., Hsiao,J.J., Cho,H.J., Wright,M.E., Wine,J.J. and Engelhardt,J.F.
    Glandular proteome identifies antiprotease cystatin C as a critical modulator of airway hydration and clearance
    Am J Respir Cell Mol Biol (2016) 54, 469-481. PubMed  Europe PubMed DOI
  135. Gren,S.T., Janciauskiene,S., Sandeep,S., Jonigk,D., Kvist,P.H., Gerwien,J.G., Hakansson,K. and Grip,O.
    The protease inhibitor cystatin C down-regulates the release of IL-beta and TNF-alpha in lipopolysaccharide activated monocytes
    J Leukoc Biol (2016) 100, 811-822. PubMed  Europe PubMed DOI
  136. He,M., Ke,P.F., Xu,J.H., Chen,W.Y., Lin,H.B., Zhang,C., Wang,Y.X., Zhuang,J.H. and Huang,X.Z.
    Performance evaluation of the Sysmex cystatin C assay on the Roche modular P analyzer
    Clin Biochem (2016) 49, 915-918. PubMed  Europe PubMed DOI  A
  137. Jurczak,P., Groves,P., Szymanska,A. and Rodziewicz-Motowidlo,S.
    Human cystatin C monomer, dimer, oligomer, and amyloid structures are related to health and disease
    FEBS Lett (2016) 590, 4192-4201. PubMed  Europe PubMed DOI
  138. Mori,J., Tanikawa,C., Funauchi,Y., Lo,P.H., Nakamura,Y. and Matsuda,K.
    Cystatin C as a p53-inducible apoptotic mediator that regulates cathepsin L activity
    Cancer Sci (2016) 107, 298-306. PubMed  Europe PubMed DOI
  139. Nguyen,A. and Hulleman,J.D.
    Evidence of alternative cystatin C signal sequence cleavage which is influenced by the A25T polymorphism
    PLoS ONE (2016) 11, e0147684-e0147684. PubMed  Europe PubMed DOI  PMC  EPMC  M
  140. Perlenfein,T.J. and Murphy,R.M.
    Expression, purification, and characterization of human cystatin C monomers and oligomers
    Protein Expr Purif (2016) 117, 35-43. PubMed  Europe PubMed DOI  E
  141. Sant'Anna,R., Navarro,S., Ventura,S., Paraoan,L. and Foguel,D.
    Amyloid properties of the leader peptide of variant B cystatin C: implications for Alzheimer and macular degeneration
    FEBS Lett (2016) 590, 644-654. PubMed  Europe PubMed DOI  M
  142. Song,W., Jiang,K.J., Zhang,F.Y., Zhao,M. and Ma,L.B.
    Molecular cloning and gene expression analysis of cystatin C-like proteins in spinyhead croaker Collichthys lucidus
    Genet Mol Res (2016) 15 PubMed  Europe PubMed DOI
    143. 2015
  143. Butler,J.M., Sharif,U., Ali,M., McKibbin,M., Thompson,J.P., Gale,R., Yang,Y.C., Inglehearn,C. and Paraoan,L.
    A missense variant in CST3 exerts a recessive effect on susceptibility to age-related macular degeneration resembling its association with Alzheimer's disease
    Hum Genet (2015) 134, 705-715. PubMed  Europe PubMed DOI  M
  144. Davis,P.J., Holmes,D., Waltho,J.P. and Staniforth,R.A.
    Limited proteolysis reveals that amyloids from the 3D domain-swapping cystatin B have a non-native beta-sheet topology
    J Mol Biol (2015) 427, 2418-2434. PubMed  Europe PubMed DOI
  145. Ghys,L.F., Paepe,D., Lefebvre,H.P., Taffin,E.R., Hesta,M., Delanghe,J.R., Smets,P., Vandendriessche,V. and Daminet,S.
    The effect of feeding, storage and anticoagulant on feline serum cystatin C
    Vet J (2015) 206, 91-96. PubMed  Europe PubMed DOI
  146. Kyostio-Moore,S., Piraino,S., Berthelette,P., Moran,N., Serriello,J., Bendele,A., Sookdeo,C., Nambiar,B., Ewing,P., Armentano,D. and Matthews,G.L.
    Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis
    Arthritis Res Ther (2015) 17, 5-5. PubMed  Europe PubMed DOI
  147. Tsiolaki,P.L., Hamodrakas,S.J. and Iconomidou,V.A.
    The pentapeptide LQVVR plays a pivotal role in human cystatin C fibrillization
    FEBS Lett (2015) 589, 159-164. PubMed  Europe PubMed DOI
  148. Tsiolaki,P.L., Louros,N.N., Hamodrakas,S.J. and Iconomidou,V.A.
    Exploring the 'aggregation-prone' core of human cystatin C: a structural study
    J Struct Biol (2015) 191, 272-280. PubMed  Europe PubMed DOI
  149. Xu,Y., Ding,Y., Li,X. and Wu,X.
    Cystatin C is a disease-associated protein subject to multiple regulation
    Immunol Cell Biol (2015) 93, 442-451. PubMed  Europe PubMed DOI
  150. Zha,Z., Zhao,X., Liu,W., Zhang,M., Tang,B., Wu,B., Qu,F., Chen,X., Wu,X., Cao,L. and Guo,H.
    Preparation and identification of a monoclonal antibody against cystatin C
    Monoclon Antib Immunodiagn Immunother (2015) 34, 334-340. PubMed  Europe PubMed DOI
  151. Zhou,Y., Zhou,Y., Li,J., Chen,J., Yao,Y., Yu,L., Peng,D., Wang,M., Su,D., He,Y. and Gou,L.
    Efficient expression, purification and characterization of native human cystatin C in Escherichia coli periplasm
    Protein Expr Purif (2015) 111, 18-22. PubMed  Europe PubMed DOI  E
    152. 2014
  152. Li,Y.M., Li,D.J., Xu,X.J., Cui,M., Zhen,H.H. and Wang,Q.
    Effect of codon optimization on expression levels of human cystatin C in Pichia pastoris
    Genet Mol Res (2014) 13, 4990-5000. PubMed  Europe PubMed DOI  E
  153. O'Seaghdha,C.M., Tin,A., Yang,Q., Katz,R., Liu,Y., Harris,T., Astor,B., Coresh,J., Fox,C.S., Kao,W.H. and Shlipak,M.G.
    Association of a cystatin C gene variant with cystatin C levels, CKD, and risk of incident cardiovascular disease and mortality
    Am J Kidney Dis (2014) 63, 16-22. PubMed  Europe PubMed DOI  M
  154. Whelly,S., Serobian,G., Borchardt,C., Powell,J., Johnson,S., Hakansson,K., Lindstrom,V., Abrahamson,M., Grubb,A. and Cornwall,G.A.
    Fertility defects in mice expressing the L68Q variant of human cystatin C: a role for amyloid in male infertility
    J Biol Chem (2014) 289, 7718-7729. PubMed  Europe PubMed DOI  M
  155. Zhang,Q., Zhao,X., Xu,X., Tang,B., Zha,Z., Zhang,M., Yao,D., Chen,X., Wu,X., Cao,L. and Guo,H.
    Expression and purification of soluble human cystatin C in Escherichia coli with maltose-binding protein as a soluble partner
    Protein Expr Purif (2014) 104C, 14-19. PubMed  Europe PubMed DOI  E
    156. 2013
  156. Ahn,S.J., Bak,H.J., Park,J.H., Lee,J.Y., Kim,N.Y., Han,J.W., Jo,H.I., Chung,J.K. and Lee,H.H.
    Olive flounder (Paralichthys olivaceus) cystatin C: cloning, mRNA expression, and enzymatic characterization of olive flounder cystatin C
    Appl Biochem Biotechnol (2013) 170, 1216-1228. PubMed  Europe PubMed DOI
  157. Hayashi,M., Iwamoto,S., Sato,S., Sudo,S., Takagi,M., Sakai,H. and Hayakawa,T.
    Efficient production of recombinant cystatin C using a peptide-tag, 4AaCter, that facilitates formation of insoluble protein inclusion bodies in Escherichia coli
    Protein Expr Purif (2013) 88, 230-234. PubMed  Europe PubMed DOI  E
  158. He,J., Xu,L., Zhang,S., Guan,J., Shen,M., Li,H. and Song,Y.
    Steered molecular dynamics simulation of the binding of the beta2 and beta3 regions in domain-swapped human cystatin C dimer
    J Mol Model (2013) 19, 825-832. PubMed  Europe PubMed DOI
  159. He,J., Xu,L., Zou,Z., Ueyama,N., Li,H., Kato,A., Jones,G.W. and Song,Y.
    Molecular dynamics simulation to investigate the impact of disulfide bond formation on conformational stability of chicken cystatin I66Q mutant
    J Biomol Struct Dyn (2013) 31, 1101-1110. PubMed  Europe PubMed DOI
  160. Orlikowska,M., Szymanska,A., Borek,D., Otwinowski,Z., Skowron,P. and Jankowska,E.
    Structural characterization of V57D and V57P mutants of human cystatin C, an amyloidogenic protein
    Acta Crystallogr D Biol Crystallogr (2013) 69, 577-586. PubMed  Europe PubMed DOI  S
  161. Toprak,A.E., Kinas,B.E. and Uras,A.R.
    Methodological evaluation of a turbidimetric method for the analysis of serum cystatin C and comparison with a nephelometric method
    Turk J Biochem (2013) 38, 238-242. DOI  A
  162. Wallin,H., Abrahamson,M. and Ekstrom,U.
    Cystatin C properties crucial for uptake and inhibition of intracellular target enzymes
    J Biol Chem (2013) 288, 17019-17029. PubMed  Europe PubMed DOI
  163. Wilson,M.E., Boumaza,I. and Bowser,R.
    Measurement of cystatin C functional activity in the cerebrospinal fluid of amyotrophic lateral sclerosis and control subjects
    Fluids Barriers CNS (2013) 10, 15-15. PubMed  Europe PubMed DOI  A
    164. 2012
  164. Hua,Y., Zhao,H., Lu,X., Kong,Y. and Jin,H.
    Meta-analysis of the cystatin C (CST3) gene G73A polymorphism and susceptibility to Alzheimer's disease
    Int J Neurosci (2012) 122, 431-438. PubMed  Europe PubMed DOI  M
  165. Laurent-Matha,V., Huesgen,P.F., Masson,O., Derocq,D., Prebois,C., Gary-Bobo,M., Lecaille,F., Rebiere,B., Meurice,G., Orear,C., Hollingsworth,R.E., Abrahamson,M., Lalmanach,G., Overall,C.M. and Liaudet-Coopman,E.
    Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment
    FASEB J (2012) 26, 5172-5181. PubMed  Europe PubMed DOI
  166. Ristiniemi,N., Qin,Q.P., Lindstrom,V., Grubb,A. and Pettersson,K.
    Quantification of cystatin C by time-resolved fluorometry-based immunoassays
    J Immunol Methods (2012) 378, 56-61. PubMed  Europe PubMed DOI  A
  167. Shen,M., Guan,J., Xu,L., Yu,Y., He,J., Jones,G.W. and Song,Y.
    Steered molecular dynamics simulations on the binding of the appendant structure and helix-beta2 in domain-swapped human cystatin C dimer
    J Biomol Struct Dyn (2012) 30, 652-661. PubMed  Europe PubMed DOI
  168. Szymanska,A., Jankowska,E., Orlikowska,M., Behrendt,I., Czaplewska,P. and Rodziewicz-Motowidlo,S.
    Influence of point mutations on the stability, dimerization, and oligomerization of human cystatin C and its L68Q variant
    Front Mol Neurosci (2012) 5, 82-82. PubMed  Europe PubMed DOI  PMC  EPMC
  169. Wang,Q., Mei,C., Zhen,H. and Zhu,J.
    Codon preference optimization increases prokaryotic cystatin C expression
    J Biomed Biotechnol (2012) 2012, 732017-732017. PubMed  Europe PubMed DOI  PMC  EPMC  E
    170. 2011
  170. Backlund,A., Holmdahl,M., Mattsson,R., Hakansson,K., Lindstrom,V., Nandakumar,K.S., Grubb,A. and Holmdahl,R.
    Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development
    Arthritis Res Ther (2011) 13, R54-R54. PubMed  Europe PubMed DOI
  171. Maahs,D.M., Jalal,D., McFann,K., Rewers,M. and Snell-Bergeon,J.K.
    Systematic shifts in cystatin C between 2006 and 2010
    Clin J Am Soc Nephrol (2011) 6, 1952-1955. PubMed  Europe PubMed DOI  A
  172. Orlikowska,M., Jankowska,E., Kolodziejczyk,R., Jaskolski,M. and Szymanska,A.
    Hinge-loop mutation can be used to control 3D domain swapping and amyloidogenesis of human cystatin C
    J Struct Biol (2011) 173, 406-413. PubMed  Europe PubMed DOI
  173. Orlikowska,M., Jankowska,E., Borek,D., Otwinowski,Z., Skowron,P. and Szymanska,A.
    Crystallization and preliminary X-ray diffraction analysis of Val57 mutants of the amyloidogenic protein human cystatin C
    Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 67, 1608-1611. PubMed  Europe PubMed DOI  PMC  EPMC
  174. Stner,G., Lindstr,M., Postnikov,A.B., Solovyeva,T.I., Emilsson,S.I. and Grubb,A.
    High throughput testing of drug library substances and monoclonal antibodies for capacity to reduce formation of cystatin C dimers to identify candidates for treatment of hereditary cystatin C amyloid angiopathy
    Scand J Clin Lab Invest (2011) 71, 676-682. PubMed  Europe PubMed DOI
  175. van Kasteren,S.I., Berlin,I., Colbert,J.D., Keane,D., Ovaa,H. and Watts,C.
    A multifunctional protease inhibitor to regulate endolysosomal function
    ACS Chem Biol (2011) 6, 1198-1204. PubMed  Europe PubMed DOI  I
    176. 2010
  176. D'Adamio,L.
    Role of cystatin C in neuroprotection and its therapeutic implications
    Am J Pathol (2010) 177, 2163-2165. PubMed  Europe PubMed DOI  U
  177. Erlandsen,E.J. and Randers,E.
    Performance evaluation of the Roche Tina-quant Cystatin C assay and reference interval for cystatin C in healthy blood donors
    Scand J Clin Lab Invest (2010) 70, 300-304. PubMed  Europe PubMed DOI  A
  178. Hedrich,J., Lottaz,D., Meyer,K., Yiallouros,I., Jahnen-Dechent,W., StoÆ^cker,W. and Becker-Pauly,C.
    Fetuin-A and cystatin C are endogenous inhibitors of human meprin metalloproteases
    Biochemistry (2010) 49, 8599-8607. PubMed  Europe PubMed DOI
  179. Kaur,G., Mohan,P., Pawlik,M., Derosa,S., Fajiculay,J., Che,S., Grubb,A., Ginsberg,S.D., Nixon,R.A. and Levy,E.
    Cystatin C rescues degenerating neurons in a cystatin B-knockout mouse model of progressive myoclonus epilepsy
    Am J Pathol (2010) 177, 2256-2267. PubMed  Europe PubMed DOI
  180. Kolodziejczyk,R., Michalska,K., Hernandez-Santoyo,A., Wahlbom,M., Grubb,A. and Jaskolski,M.
    Crystal structure of human cystatin C stabilized against amyloid formation
    FEBS J (2010) 277, 1726-1737. PubMed  Europe PubMed DOI  M  S
  181. Li,J., Dunn,W., Breaud,A., Elliott,D., Sokoll,L.J. and Clarke,W.
    Analytical performance of 4 automated assays for measurement of cystatin C
    Clin Chem (2010) 56, 1336-1339. PubMed  Europe PubMed DOI  A
  182. Nakata,J., Nakahari,A., Takahashi,C., Chikazawa,S., Hori,Y., Kanai,K., Ito,N., Higuchi,S. and Hoshi,F.
    Molecular cloning, expression in Escherichia coli, and development of monoclonal antibodies to feline cystatin C
    Vet Immunol Immunopathol (2010) 138, 231-234. PubMed  Europe PubMed DOI  E
  183. Schulte,S., Sun,J., Libby,P., Macfarlane,L., Sun,C., Lopez-Ilasaca,M., Shi,G.P. and Sukhova,G.K.
    Cystatin C deficiency promotes inflammation in angiotensin II-induced abdominal aortic aneurisms in atherosclerotic mice
    Am J Pathol (2010) 177, 456-463. PubMed  Europe PubMed DOI  K
  184. Wallin,H., Bjarnadottir,M., Vogel,L.K., Wasselius,J., Ekstrom,U. and Abrahamson,M.
    Cystatins - extra- and intracellular cysteine protease inhibitors: high-level secretion and uptake of cystatin C in human neuroblastoma cells
    Biochimie (2010) 92, 1625-1634. PubMed  Europe PubMed DOI
    185. 2008
  185. Palsdottir,A., Helgason,A., Palsson,S., Bjornsson,H.T., Bragason,B.T., Gretarsdottir,S., Thorsteinsdottir,U., Olafsson,E. and Stefansson,K.
    A drastic reduction in the life span of cystatin C L68Q carriers due to life-style changes during the last two centuries
    PLoS Genet (2008) 4, e1000099-e1000099. PubMed  Europe PubMed DOI  PMC  EPMC  M
  186. Shen,A. and Bogyo,M.
    Friend or foe? Turning a host defense protein into a pathogen's accomplice
    Chem Biol (2008) 15, 879-880. PubMed  Europe PubMed DOI
  187. Sun,B., Zhou,Y., Halabisky,B., Lo,I., Cho,S.H., Mueller-Steiner,S., Devidze,N., Wang,X., Grubb,A. and Gan,L.
    Cystatin C-cathepsin B axis regulates amyloid beta levels and associated neuronal deficits in an animal model of Alzheimer's disease
    Neuron (2008) 60, 247-257. PubMed  Europe PubMed DOI  PMC  EPMC
  188. Sundelof,J., Arnlov,J., Ingelsson,E., Sundstrom,J., Basu,S., Zethelius,B., Larsson,A., Irizarry,M.C., Giedraitis,V., Ronnemaa,E., Degerman-Gunnarsson,M., Hyman,B.T., Basun,H., Kilander,L. and Lannfelt,L.
    Serum cystatin C and the risk of Alzheimer disease in elderly men
    Neurology (2008) 71, 1072-1079. PubMed  Europe PubMed DOI  PMC  EPMC
  189. Vincents,B., Vindebro,R., Abrahamson,M. and von Pawel-Rammingen,U.
    The human protease inhibitor cystatin C is an activating cofactor for the streptococcal cysteine protease IdeS
    Chem Biol (2008) 15, 960-968. PubMed  Europe PubMed DOI
    190. 2007
  190. Del Boccio,P., Pieragostino,D., Lugaresi,A., Di Ioia,M., Pavone,B., Travaglini,D., D'Aguanno,S., Bernardini,S., Sacchetta,P., Federici,G., Di Ilio,C., Gambi,D. and Urbani,A.
    Cleavage of cystatin C is not associated with multiple sclerosis
    Ann Neurol (2007) 62, 201-204. PubMed  Europe PubMed DOI
  191. Hansson,S.F., Simonsen,A.H., Zetterberg,H., Andersen,O., Haghighi,S., Fagerberg,I., Andreasson,U., Westman-Brinkmalm,A., Wallin,A., Ruetschi,U. and Blennow,K.
    Cystatin C in cerebrospinal fluid and multiple sclerosis
    Ann Neurol (2007) 62, 193-196. PubMed  Europe PubMed DOI
  192. Hasegawa,A., Naruse,M., Hitoshi,S., Iwasaki,Y., Takebayashi,H. and Ikenaka,K.
    Regulation of glial development by cystatin C
    J Neurochem (2007) 100, 12-22. PubMed  Europe PubMed DOI
  193. Kaeser,S.A., Herzig,M.C., Coomaraswamy,J., Kilger,E., Selenica,M.L., Winkler,D.T., Staufenbiel,M., Levy,E., Grubb,A. and Jucker,M.
    Cystatin C modulates cerebral beta-amyloidosis
    Nat Genet (2007) 39, 1437-1439. PubMed  Europe PubMed DOI  M
  194. Lin,Y.M., Liu,H.L., Zhao,J.H., Huang,C.H., Fang,H.W., Ho,Y. and Chen,W.Y.
    Molecular dynamics simulations to investigate the domain swapping mechanism of human cystatin C
    Biotechnol Prog (2007) 23, 577-584. PubMed  Europe PubMed DOI
  195. Liu,H.L., Lin,Y.M., Zhao,J.H., Hsieh,M.C., Lin,H.Y., Huang,C.H., Fang,H.W., Ho,Y. and Chen,W.Y.
    Molecular dynamics simulations of human cystatin C and its L68Q varient to investigate the domain swapping mechanism
    J Biomol Struct Dyn (2007) 25, 135-144. PubMed  Europe PubMed DOI
  196. Mi,W., Pawlik,M., Sastre,M., Jung,S.S., Radvinsky,D.S., Klein,A.M., Sommer,J., Schmidt,S.D., Nixon,R.A., Mathews,P.M. and Levy,E.
    Cystatin C inhibits amyloid-beta deposition in Alzheimer's disease mouse models
    Nat Genet (2007) 39, 1440-1442. PubMed  Europe PubMed DOI  U
  197. Nakashima,I., Fujinoki,M., Fujihara,K., Kawamura,T., Nishimura,T., Nakamura,M. and Itoyama,Y.
    Alteration of cystatin C in the cerebrospinal fluid of multiple sclerosis
    Ann Neurol (2007) 62, 197-200. PubMed  Europe PubMed DOI
  198. Ni,L., Lu,J., Hou,L.B., Yan,J.T., Fan,Q., Hui,R., Cianflone,K., Wang,W. and Wang,D.W.
    Cystatin C, associated with hemorrhagic and ischemic stroke, is a strong predictor of the risk of cardiovascular events and death in Chinese
    Stroke (2007) 38, 3287-3288. PubMed  Europe PubMed DOI
  199. Vilhjalmsson,D.T., Blondal,H. and Thormodsson,F.R.
    Solubilized cystatin C amyloid is cytotoxic to cultured human cerebrovascular smooth muscle cells
    Exp Mol Pathol (2007) 83, 357-360. PubMed  Europe PubMed DOI
  200. Wahlbom,M., Wang,X., Lindstrom,V., Carlemalm,E., Jaskolski,M. and Grubb,A.
    Fibrillogenic oligomers of human cystatin C are formed by propagated domain swapping
    J Biol Chem (2007) 282, 18318-18326. PubMed  Europe PubMed DOI
    201. 2006
  201. [YEAR:20-11-2006]Gonzalez-Rivera,R., Navarro,L., Martinez-Vargas,M., Guzman-Vasquez,K., Leon-Rosario,P., Landa,A. and Prospero-Garcia,O.
    Potential participation of cystatin C in rapid eye movement sleep (REMS) modulation
    Neurosci Lett (20-11-2006) 408, 178-182. PubMed  Europe PubMed DOI
  202. [YEAR:18-1-2006]Rodziewicz-Motowidlo,S., Wahlbom,M., Wang,X., Lagiewka,J., Janowski,R., Jaskolski,M., Grubb,A. and Grzonka,Z.
    Checking the conformational stability of cystatin C and its L68Q variant by molecular dynamics studies: Why is the L68Q variant amyloidogenic?
    J Struct Biol (18-1-2006) 154, 68-78. PubMed  Europe PubMed DOI
  203. Sukhova,G.K. and Shi,G.P.
    Do cathepsins play a role in abdominal aortic aneurysm pathogenesis?
    Ann N Y Acad Sci (2006) 1085, 161-169. PubMed  Europe PubMed DOI
    204. 2005
  204. [YEAR:28-7-2005]Bengtsson,E., To,F., Hakansson,K., Grubb,A., Branen,L., Nilsson,J. and Jovinge,S.
    Lack of the cysteine protease inhibitor cystatin C promotes atherosclerosis in apolipoprotein E-deficient mice
    Arterioscler Thromb Vasc Biol (28-7-2005) 25, 2151-2156. PubMed  Europe PubMed DOI
  205. Bengtsson,E., To,F., Grubb,A., Hakansson,K., Wittgren,L., Nilsson,J. and Jovinge,S.
    Absence of the protease inhibitor cystatin C in inflammatory cells results in larger plaque area in plaque regression of apoE-deficient mice
    Atherosclerosis (2005) 180, 45-53. PubMed  Europe PubMed DOI
  206. [YEAR:22-2-2005]Cathcart,H.M., Huang,R., Lanham,I.S., Corder,E.H. and Poduslo,S.E.
    Cystatin C as a risk factor for Alzheimer disease
    Neurology (22-2-2005) 64, 755-757. PubMed  Europe PubMed DOI
  207. [YEAR:17-5-2005]Ervin,H. and Cox,J.L.
    Late stage inhibition of hematogenous melanoma metastasis by cystatin C over-expression
    Cancer Cell Int (17-5-2005) 5, 14-14. PubMed  Europe PubMed DOI  PMC  EPMC
  208. [YEAR:16-9-2005]Janowski,R., Kozak,M., Abrahamson,M., Grubb,A. and Jaskolski,M.
    3D domain-swapped human cystatin C with amyloidlike intermolecular beta-sheets
    Proteins (16-9-2005) 61, 570-578. PubMed  Europe PubMed DOI  S
  209. Pirttila,T.J., Lukasiuk,K., Hakansson,K., Grubb,A., Abrahamson,M. and Pitkanen,A.
    Cystatin C modulates neurodegeneration and neurogenesis following status epilepticus in mouse
    Neurobiol Dis (2005) 20, 241-253. PubMed  Europe PubMed DOI
  210. Samyn,M., Cheeseman,P., Bevis,L., Taylor,R., Samaroo,B., Buxton-Thomas,M., Heaton,N., Rela,M., Mieli-Vergani,G. and Dhawan,A.
    Cystatin C, an easy and reliable marker for assessment of renal dysfunction in children with liver disease and after liver transplantation
    Liver Transpl (2005) 11, 344-349. PubMed  Europe PubMed DOI
  211. [YEAR:18-1-2005]Shlipak,M.G., Katz,R., Fried,L., Jenny,N.S., Stehman-Breen,C., Newman,A., Siscovick,D., Psaty,B.M. and Sarnak,M.J.
    Cystatin-C and mortality in elderly persons with heart failure
    J Am Coll Cardiol (18-1-2005) 45, 268-271. PubMed  Europe PubMed DOI
  212. [YEAR:13-1-2005]Sukhova,G.K., Wang,B., Libby,P., Pan,J.H., Zhang,Y., Grubb,A., Fang,K., Chapman,H.A. and Shi,G.P.
    Cystatin C deficiency increases elastic lamina degradation and aortic dilatation in apolipoprotein E-null mice
    Circ Res (13-1-2005) 96, 368-375. PubMed  Europe PubMed DOI  K
  213. Xu,L., Sheng,J., Tang,Z., Wu,X., Yu,Y., Guo,H., Shen,Y., Zhou,C., Paraoan,L. and Zhou,J.
    Cystatin C prevents degeneration of rat nigral dopaminergic neurons: in vitro and in vivo studies
    Neurobiol Dis (2005) 18, 152-165. PubMed  Europe PubMed DOI
    214. 2004
  214. Brand,H.S., Lerner,U.H., Grubb,A., Beertsen,W., Nieuw Amerongen,A.V. and Everts,V.
    Family 2 cystatins inhibit osteoclast-mediated bone resorption in calvarial bone explants
    Bone (2004) 35, 689-696. PubMed  Europe PubMed DOI
  215. [YEAR:15-1-2004]Eriksson,P., Deguchi,H., Samnegard,A., Lundman,P., Boquist,S., Tornvall,P., Ericsson,C.G., Bergstrand,L., Hansson,L.O., Ye,S. and Hamsten,A.
    Human evidence that the cystatin C gene is implicated in focal progression of coronary artery disease
    Arterioscler Thromb Vasc Biol (15-1-2004) 24, 551-557. PubMed  Europe PubMed DOI  M
  216. [YEAR:30-7-2004]Janowski,R., Abrahamson,M., Grubb,A. and Jaskolski,M.
    Domain swapping in N-truncated human cystatin C
    J Mol Biol (30-7-2004) 341, 151-160. PubMed  Europe PubMed DOI
  217. Jasir,A., Kasprzykowski,F., Lindstrom,V., Schalen,C. and Grubb,A.
    New antimicrobial peptide active against Gram-positive pathogens
    Indian J Med Res (2004) 119 Suppl, 74-76. PubMed  Europe PubMed
  218. [YEAR:19-10-2004]Jernberg,T., Lindahl,B., James,S., Larsson,A., Hansson,L.O. and Wallentin,L.
    Cystatin C: a novel predictor of outcome in suspected or confirmed non-ST-elevation acute coronary syndrome
    Circulation (19-10-2004) 110, 2342-2348. PubMed  Europe PubMed DOI
  219. Nakamura,S., Hata,J., Kawamukai,M., Matsuda,H., Ogawa,M., Nakamura,K., Jing,H., Kitts,D.D. and Nakai,S.
    Enhanced anti-rotavirus action of human cystatin C by site-specific glycosylation in yeast
    Bioconjug Chem (2004) 15, 1289-1296. PubMed  Europe PubMed DOI
  220. [YEAR:17-3-2004]Nilsson,M., Wang,X., Rodziewicz-Motowidlo,S., Janowski,R., Lindstrom,V., Onnerfjord,P., Westermark,G., Grzonka,Z., Jaskolski,M. and Grubb,A.
    Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C: use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C
    J Biol Chem (17-3-2004) 279, 24236-24245. PubMed  Europe PubMed DOI
  221. Olsson,T., Nygren,J., Hakansson,K., Lundblad,C., Grubb,A., Smith,M.L. and Wieloch,T.
    Gene deletion of cystatin C aggravates brain damage following focal ischemia but mitigates the neuronal injury after global ischemia in the mouse
    Neuroscience (2004) 128, 65-71. PubMed  Europe PubMed DOI  K
  222. Outchkourov,N.S., de Kogel,W.J., Schuurman-de Bruin,A., Abrahamson,M. and Jongsma,M.A.
    Specific cysteine protease inhibitors act as deterrents of western flower thrips, Frankliniella occidentalis (Pergande), in transgenic potato
    Plant Biotechnol J (2004) 2, 439-448. PubMed  Europe PubMed DOI
  223. Paraoan,L., Ratnayaka,A., Spiller,D.G., Hiscott,P., White,M.R. and Grierson,I.
    Unexpected intracellular localization of the AMD-associated cystatin C variant
    Traffic (2004) 5, 884-895. PubMed  Europe PubMed DOI
  224. Pawlik,M., Sastre,M., Calero,M., Mathews,P.M., Schmidt,S.D., Nixon,R.A. and Levy,E.
    Overexpression of human cystatin C in transgenic mice does not affect levels of endogenous brain amyloid beta peptide
    J Mol Neurosci (2004) 22, 13-18. PubMed  Europe PubMed DOI
  225. Pritchett,J. and Baldwin,S.A.
    The effect of nitrogen source on yield and glycosylation of a human cystatin C mutant expressed in Pichia pastoris
    J Ind Microbiol Biotechnol (2004) 31, 553-558. PubMed  Europe PubMed DOI  E
    226. 2003
  226. Jasir,A., Kasprzykowski,F., Kasprzykowska,R., Lindstrom,V., Schalen,C. and Grubb,A.
    New antimicrobial cystatin C-based peptide active against gram-positive bacterial pathogens, including methicillin-resistant Staphylococcus aureus and multiresistant coagulase-negative staphylococci
    APMIS (2003) 111, 1004-1010. PubMed  Europe PubMed DOI
  227. Paraoan,L., Grierson,I. and Maden,B.E.
    Fate of cystatin C lacking the leader sequence in RPE cells
    Exp Eye Res (2003) 76, 753-756. PubMed  Europe PubMed DOI  M
    228. 2002
  228. Dickinson,D.P., Thiesse,M. and Hicks,M.J.
    Expression of type 2 cystatin genes CST1-CST5 in adult human tissues and the developing submandibular gland
    DNA Cell Biol (2002) 21, 47-65. PubMed  Europe PubMed DOI
  229. Gerhartz,B. and Abrahamson,M.
    Physico-chemical properties of the N-terminally truncated L68Q cystatin C found in amyloid deposits of brain haemorrhage patients
    Biol Chem (2002) 383, 301-305. PubMed  Europe PubMed DOI
  230. Matsuoka,Y., Serizawa,A., Yoshioka,T., Yamamura,J., Morita,Y., Kawakami,H., Toba,Y., Takada,Y. and Kumegawa,M.
    Cystatin C in milk basic protein (MBP) and its inhibitory effect on bone resorption in vitro
    Biosci Biotechnol Biochem (2002) 66, 2531-2536. PubMed  Europe PubMed DOI
    231. 2001
  231. Aronica,E., van Vliet,E.A., Hendriksen,E., Troost,D., Lopes da Silva,F.H. and Gorter,J.A.
    Cystatin C, a cysteine protease inhibitor, is persistently up-regulated in neurons and glia in a rat model for mesial temporal lobe epilepsy
    Eur J Neurosci (2001) 14, 1485-1491. PubMed  Europe PubMed DOI
  232. Calero,M., Pawlik,M., Soto,C., Castano,E.M., Sigurdsson,E.M., Kumar,A., Gallo,G., Frangione,B. and Levy,E.
    Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type
    J Neurochem (2001) 77, 628-637. PubMed  Europe PubMed DOI
  233. Deng,A., Irizarry,M.C., Nitsch,R.M., Growdon,J.H. and Rebeck,G.W.
    Elevation of cystatin C in susceptible neurons in Alzheimer's disease
    Am J Pathol (2001) 159, 1061-1068. PubMed  Europe PubMed DOI  PMC  EPMC
  234. Janowski,R., Kozak,M., Jankowska,E., Grzonka,Z., Grubb,A., Abrahamson,M. and Jaskolski,M.
    Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping
    Nat Struct Biol (2001) 8, 316-320. PubMed  Europe PubMed DOI  S
  235. Wasselius,J., Hakansson,K., Johansson,K., Abrahamson,M. and Ehinger,B.
    Identification and localization of retinal cystatin C
    Invest Ophthalmol Vis Sci (2001) 42, 1901-1906. PubMed  Europe PubMed
    236. 2000
  236. Finckh,U., Von der,K., Velden,J., Michel,T., Andresen,B., Deng,A., Zhang,J., Muller-Thomsen,T., Zuchowski,K., Menzer,G., Mann,U., Papassotiropoulos,A., Heun,R., Zurdel,J., Holst,F., Benussi,L., Stoppe,G., Reiss,J., Miserez,A.R., Staehelin,H.B., Rebeck,G.W., Hyman,B.T., Binetti,G., Hock,C., Growdon,J.H. and Nitsch,R.M.
    Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease
    Arch Neurol (2000) 57, 1579-1583. PubMed  Europe PubMed  M
  237. Johansson,L., Grubb,A., Abrahamson,M., Kasprzykowski,F., Kasprzykowska,R., Grzonka,Z. and Lerner,U.H.
    A peptidyl derivative structurally based on the inhibitory center of cystatin C inhibits bone resorption in vitro
    Bone (2000) 26, 451-459. PubMed  Europe PubMed DOI  I
  238. Kasprzykowski,F., Schalen,C., Kasprzykowska,R., Jastrzebska,B. and Grubb,A.
    Synthesis and antibacterial properties of peptidyl derivatives and cyclopeptides structurally based upon the inhibitory centre of human cystatin C. Dissociation of antiproteolytic and antibacterial effects
    APMIS (2000) 108, 473-481. PubMed  Europe PubMed
  239. Li,F., An,H., Seymour,T.A. and Barnes,D.W.
    Rainbow trout (Oncorhynchus mykiss) cystatin C: expression in Escherichia coli and properties of the recombinant protease inhibitor
    Comp Biochem Physiol B Biochem Mol Biol (2000) 125, 493-502. PubMed  Europe PubMed DOI
  240. [YEAR:29-12-2000]Pavlova,A., Krupa,J.C., Mort,J.S., Abrahamson,M. and Bjork,I.
    Cystatin inhibition of cathepsin B requires dislocation of the proteinase occluding loop. Demonstration by release of loop anchoring through mutation of His110
    FEBS Lett (29-12-2000) 487, 156-160. PubMed  Europe PubMed DOI
    241. 1999
  241. [YEAR:2-7-1999]Alvarez-Fernandez,M., Barrett,A.J., Gerhartz,B., Dando,P.M., Ni,J. and Abrahamson,M.
    Inhibition of mammalian legumain by some cystatins is due to a novel second reactive site
    J Biol Chem (2-7-1999) 274, 19195-19203. PubMed  Europe PubMed DOI
  242. Benedikz,E., Merz,G.S., Schwenk,V., Johansen,T.E., Wisniewski,H.M. and Rushbrook,J.I.
    Cellular processing of the amyloidogenic cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type
    Amyloid (1999) 6, 172-182. PubMed  Europe PubMed
  243. Hiltke,T.R., Lee,T.C. and Bobek,L.A.
    Structure/function analysis of human cystatin SN and comparison of the cysteine proteinase inhibitory profiles of human cystatins C and SN
    J Dent Res (1999) 78, 1401-1409. PubMed  Europe PubMed
  244. [YEAR:15-6-1999]Olsson,S.L., Ek,B. and Bjork,I.
    The affinity and kinetics of inhibition of cysteine proteinases by intact recombinant bovine cystatin C
    Biochim Biophys Acta (15-6-1999) 1432, 73-81. PubMed  Europe PubMed DOI
  245. [YEAR:16-7-1999]Popovic,T., Cimerman,N., Dolenc,I., Ritonja,A. and Brzin,J.
    Cathepsin L is capable of truncating cystatin C of 11 N-terminal amino acids
    FEBS Lett (16-7-1999) 455, 92-96. PubMed  Europe PubMed DOI
    246. 1998
  246. [YEAR:8-12-1998]Gerhartz,B., Ekiel,I. and Abrahamson,M.
    Two stable unfolding intermediates of the disease-causing L68Q variant of human cystatin C
    Biochemistry (8-12-1998) 37, 17309-17317. PubMed  Europe PubMed DOI
  247. [YEAR:24-3-1998]Hall,A., Ekiel,I., Mason,R.W., Kasprzykowski,F., Grubb,A. and Abrahamson,M.
    Structural basis for different inhibitory specificities of human cystatins C and D
    Biochemistry (24-3-1998) 37, 4071-4079. PubMed  Europe PubMed DOI
  248. Li,F., An,H., Seymour,T.A., Bradford,C.S., Morrissey,M.T., Bailey,G.S., Helmrich,A. and Barnes,D.W.
    Molecular cloning, sequence analysis and expression distribution of rainbow trout (Oncorhynchus mykiss) cystatin C
    Comp Biochem Physiol B Biochem Mol Biol (1998) 121, 135-143. PubMed  Europe PubMed DOI
  249. [YEAR:1-3-1998]Mason,R.W., Sol-Church,K. and Abrahamson,M.
    Amino acid substitutions in the N-terminal segment of cystatin C create selective protein inhibitors of lysosomal cysteine proteinases
    Biochem J (1-3-1998) 330, 833-838. PubMed  Europe PubMed  PMC  EPMC
  250. Nakamura,S., Ogawa,M. and Nakai,S.
    Effects of polymannosylation of recombinant cystatin C in yeast on its stability and activity
    J Agric Food Chem (1998) 46, 2882-2887.
  251. [YEAR:23-1-1998]Nycander,M., Estrada,S., Mort,J.S., Abrahamson,M. and Bjork,I.
    Two-step mechanism of inhibition of cathepsin B by cystatin C due to displacement of the proteinase occluding loop
    FEBS Lett (23-1-1998) 422, 61-64. PubMed  Europe PubMed DOI
  252. [YEAR:8-5-1998]Wei,L., Berman,Y., Castano,E.M., Cadene,M., Beavis,R.C., Devi,L. and Levy,E.
    Instability of the amyloidogenic cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type
    J Biol Chem (8-5-1998) 273, 11806-11814. PubMed  Europe PubMed DOI
    253. 1997
  253. Berti,P.J., Ekiel,I., Lindahl,P., Abrahamson,M. and Storer,A.C.
    Affinity purification and elimination of methionine oxidation in recombinant human cystatin C
    Protein Expr Purif (1997) 11, 111-118. PubMed  Europe PubMed DOI
  254. Ekiel,I., Abrahamson,M., Fulton,D.B., Lindahl,P., Storer,A.C., Levadoux,W., Lafrance,M., Labelle,S., Pomerleau,Y., Groleau,D., LeSauteur,L. and Gehring,K.
    NMR structural studies of human cystatin C dimers and monomers
    J Mol Biol (1997) 271, 266-277. PubMed  Europe PubMed DOI
  255. Merz,G.S., Benedikz,E., Schwenk,V., Johansen,T.E., Vogel,L.K., Rushbrook,J.I. and Wisniewski,H.M.
    Human cystatin C forms an inactive dimer during intracellular trafficking in transfected CHO cells
    J Cell Physiol (1997) 173, 423-432. PubMed  Europe PubMed DOI
  256. [YEAR:5-12-1997]Olsson,S.L., Ek,B., Wilm,M., Broberg,S., Rask,L. and Bjork,I.
    Molecular cloning and N-terminal analysis of bovine cystatin C. Identification of a full-length N-terminal region
    Biochim Biophys Acta (5-12-1997) 1343, 203-210. PubMed  Europe PubMed DOI
    257. 1996
  257. Abrahamson,M.
    Molecular basis for amyloidosis related to hereditary brain hemorrhage
    Scand J Clin Lab Invest Suppl (1996) 226, 47-56. PubMed  Europe PubMed
  258. Bjork,I., Brieditis,I., Raub-Segall,E., Pol,E., Hakansson,K. and Abrahamson,M.
    The importance of the second hairpin loop of cystatin C for proteinase binding. Characterization of the interaction of Trp-106 variants of the inhibitor with cysteine proteinases
    Biochemistry (1996) 35, 10720-10726. PubMed  Europe PubMed DOI
  259. Ekiel,I. and Abrahamson,M.
    Folding-related dimerization of human cystatin C
    J Biol Chem (1996) 271, 1314-1321. PubMed  Europe PubMed DOI
  260. Hakansson,K., Huh,C., Grubb,A., Karlsson,S. and Abrahamson,M.
    Mouse and rat cystatin C: Escherichia coli production, characterization and tissue distribution
    Comp Biochem Physiol B Biochem Mol Biol (1996) 114, 303-311. PubMed  Europe PubMed DOI  E
  261. Wei,L.H., Walker,L.C. and Levy,E.
    Cystatin C. Icelandic-like mutation in an animal model of cerebrovascular beta-amyloidosis
    Stroke (1996) 27, 2080-2085. PubMed  Europe PubMed
    262. 1995
  262. [YEAR:1-3-1995]Bjork,I., Brieditis,I. and Abrahamson,M.
    Probing the functional role of the N-terminal region of cystatins by equilibrium and kinetic studies of the binding of Gly-11 variants of recombinant human cystatin C to target proteinases
    Biochem J (1-3-1995) 306, 513-518. PubMed  Europe PubMed  PMC  EPMC
  263. Graffagnino,C., Herbstreith,M.H., Schmechel,D.E., Levy,E., Roses,A.D. and Alberts,M.J.
    Cystatin C mutation in an elderly man with sporadic amyloid angiopathy and intracerebral hemorrhage
    Stroke (1995) 26, 2190-2193. PubMed  Europe PubMed
    264. 1994
  264. Abrahamson,M.
    Cystatins
    Methods Enzymol (1994) 244, 685-700. PubMed  Europe PubMed DOI  V
  265. Abrahamson,M. and Grubb,A.
    Increased body temperature accelerates aggregation of the Leu-68 - >Gln mutant cystatin C, the amyloid-forming protein in hereditary cystatin C amyloid angiopathy
    Proc Natl Acad Sci U S A (1994) 91, 1416-1420. PubMed  Europe PubMed  PMC  EPMC
  266. Berti,P.J. and Storer,A.C.
    Local pH-dependent conformational changes leading to proteolytic susceptibility of cystatin C
    Biochem J (1994) 302, 411-416. PubMed  Europe PubMed  PMC  EPMC
  267. Bjork,I., Pol,E., Raub-Segall,E., Abrahamson,M., Rowan,A.D. and Mort,J.S.
    Differential changes in the association and dissociation rate constants for binding of cystatins to target proteinases occurring on N-terminal truncation of the inhibitors indicate that the interaction mechanism varies with different enzymes
    Biochem J (1994) 299, 219-225. PubMed  Europe PubMed  PMC  EPMC
  268. Lindahl,P., Ripoll,D., Abrahamson,M., Mort,J.S. and Storer,A.C.
    Evidence for the interaction of valine-10 in cystatin C with the S2 subsite of cathepsin B
    Biochemistry (1994) 33, 4384-4392. PubMed  Europe PubMed
    269. 1993
  269. Balbin,M., Grubb,A. and Abrahamson,M.
    An Ala/Thr variation in the coding region of the human cystatin C gene (CST3) detected as a SstII polymorphism
    Hum Genet (1993) 92, 206-207. PubMed  Europe PubMed
  270. [YEAR:1-4-1993]Hall,A., Dalboge,H., Grubb,A. and Abrahamson,M.
    Importance of the evolutionarily conserved glycine residue in the N-terminal region of human cystatin C (Gly-11) for cysteine endopeptidase inhibition
    Biochem J (1-4-1993) 291, 123-129. PubMed  Europe PubMed  PMC  EPMC
    271. 1991
  271. Abrahamson,M., Buttle,D.J., Mason,R.W., Hansson,H., Grubb,A., Lilja,H. and Ohlsson,K.
    Regulation of cystatin C activity by serine proteinases
    Biomed Biochim Acta (1991) 50, 587-593. PubMed  Europe PubMed
  272. [YEAR:1-2-1991]Abrahamson,M., Mason,R.W., Hansson,H., Buttle,D.J., Grubb,A. and Ohlsson,K.
    Human cystatin C. Role of the N-terminal segment in the inhibition of human cysteine proteinases and in its inactivation by leucocyte elastase
    Biochem J (1-2-1991) 273, 621-626. PubMed  Europe PubMed  PMC  EPMC
  273. Bromme,D., Rinne,R. and Kirschke,H.
    Tight-binding inhibition of cathepsin S by cystatins
    Biomed Biochim Acta (1991) 50, 631-635. PubMed  Europe PubMed
  274. Collins,A.R. and Grubb,A.
    Inhibitory effects of recombinant human cystatin C on human coronaviruses
    Antimicrobial Agents Chemother (1991) 35, 2444-2446. PubMed  Europe PubMed  PMC  EPMC
    275. 1990
  275. Abrahamson,M., Olafsson,I., Palsdottir,A., Ulvsback,M., Lundwall,A., Jensson,O. and Grubb,A.
    Structure and expression of the human cystatin C gene
    Biochem J (1990) 268, 287-294. PubMed  Europe PubMed  PMC  EPMC
  276. Bjorck,L., Grubb,A. and Kjellen,L.
    Cystatin C, a human proteinase inhibitor, blocks replication of herpes simplex virus
    J Virol (1990) 64, 941-943. PubMed  Europe PubMed  PMC  EPMC
  277. Chapman,H.A., Jr., Reilly,J.J., Jr., Yee,R. and Grubb,A.
    Identification of cystatin C, a cysteine proteinase inhibitor, as a major secretory product of human alveolar macrophages in vitro
    Am Rev Respir Dis (1990) 141, 698-705. PubMed  Europe PubMed DOI
  278. Esnard,F., Esnard,A., Faucher,D., Capony,J.P., Derancourt,J., Brillard,M. and Gauthier,F.
    Rat cystatin C: the complete amino acid sequence reveals a site for N-glycosylation
    Biol Chem Hoppe Seyler (1990) 371 Suppl, 161-166. PubMed  Europe PubMed
  279. Grubb,A., Abrahamson,M., Olafsson,I., Trojnar,J., Kasprzykowska,R., Kasprzykowski,F. and Grzonka,Z.
    Synthesis of cysteine proteinase inhibitors structurally based on the proteinase interacting N-terminal region of human cystatin C
    Biol Chem Hoppe Seyler (1990) 371 Suppl, 137-144. PubMed  Europe PubMed
  280. Palsdottir,A., Jonsdottir,S., Abrahamson,M., Grubb,A. and Jensson,O.
    Three RFLPs at the 3' end of the cystatin C gene, the disease gene in hereditary cystatin C amyloid angiopathy (HCCAA) in Iceland
    Nucleic Acids Res (1990) 18, 7471-7471. PubMed  Europe PubMed  PMC  EPMC
    281. 1989
  281. Abrahamson,M., Islam,M.Q., Szpirer,J., Szpirer,C. and Levan,G.
    The human cystatin C gene (CST3), mutated in hereditary cystatin C amyloid angiopathy, is located on chromosome 20
    Hum Genet (1989) 82, 223-226. PubMed  Europe PubMed
    282. 1988
  282. Abrahamson,M., Dalboge,H., Olafsson,I., Carlsen,S. and Grubb,A.
    Efficient production of native, biologically active human cystatin C by Escherichia coli
    FEBS Lett (1988) 236, 14-18. PubMed  Europe PubMed DOI
  283. Palsdottir,A., Abrahamson,M., Thorsteinsson,L., Arnason,A., Olafsson,I., Grubb,A. and Jensson,O.
    Mutation in cystatin C gene causes hereditary brain haemorrhage
    Lancet (1988) 2, 603-604. PubMed  Europe PubMed
    284. 1987
  284. Abrahamson,M., Grubb,A., Olafsson,I. and Lundwall,A.
    Molecular cloning and sequence analysis of cDNA coding for the precursor of the human cysteine proteinase inhibitor cystatin C
    FEBS Lett (1987) 216, 229-233. PubMed  Europe PubMed
  285. Abrahamson,M., Ritonja,A., Brown,M.A., Grubb,A., Machleidt,W. and Barrett,A.J.
    Identification of the probable inhibitory reactive sites of the cysteine proteinase inhibitors human cystatin C and chicken cystatin
    J Biol Chem (1987) 262, 9688-9694. PubMed  Europe PubMed
  286. [YEAR:25-8-1986]Abrahamson,M., Barrett,A.J., Salvesen,G. and Grubb,A.
    Isolation of six cysteine proteinase inhibitors from human urine. Their physicochemical and enzyme kinetic properties and concentrations in biological fluids
    J Biol Chem (25-8-1986) 261, 11282-11289. PubMed  Europe PubMed
    287. 1986
  287. Ghiso,J., Pons-Estel,B. and Frangione,B.
    Hereditary cerebral amyloid angiopathy: the amyloid fibrils contain a protein which is a variant of cystatin C, an inhibitor of lysosomal cysteine proteases
    Biochem Biophys Res Commun (1986) 136, 548-554. PubMed  Europe PubMed
  288. Ghiso,J., Jensson,O. and Frangione,B.
    Amyloid fibrils in hereditary cerebral hemorrhage with amyloidosis of Icelandic type is a variant of gamma-trace basic protein (cystatin C)
    Proc Natl Acad Sci U S A (1986) 83, 2974-2978. PubMed  Europe PubMed  PMC  EPMC
    289. 1985
  289. Grubb,A. and Lofberg,H.
    Human gamma-trace. Structure, function and clinical use of concentration measurements
    Scand J Clin Lab Invest Suppl (1985) 45, Suppl.177, 7-13. PubMed  Europe PubMed
  290. [YEAR:1-7-1985]Hirado,M., Tsunasawa,S., Sakiyama,F., Niinobe,M. and Fujii,S.
    Complete amino acid sequence of bovine colostrum low-Mr cysteine proteinase inhibitor
    FEBS Lett (1-7-1985) 186, 41-45. PubMed  Europe PubMed DOI
  291. [YEAR:25-4-1985]Hochwald,G.M. and Thorbecke,G.J.
    Abnormal metabolism or reduced transport of CSF gamma-trace microprotein in hereditary cerebral hemorrhage with amyloidosis
    N Engl J Med (25-4-1985) 312, 1127-1128. PubMed  Europe PubMed
  292. [YEAR:29-3-1985]Korant,B.D., Brzin,J. and Turk,V.
    Cystatin, a protein inhibitor of cysteine proteases alters viral protein cleavages in infected human cells
    Biochem Biophys Res Commun (29-3-1985) 127, 1072-1076. PubMed  Europe PubMed
  293. Moller,C.A., Lofberg,H., Grubb,A.O., Olsson,S.O., Davies,M.E. and Barrett,A.J.
    Distribution of cystatin C (gamma-trace), an inhibitor of lysosomal cysteine proteinases, in the anterior lobe of simian and human pituitary glands
    Neuroendocrinology (1985) 41, 400-404. PubMed  Europe PubMed
  294. Rohrlich,S.T., Levy,H. and Rifkin,D.B.
    Purification and characterization of a low molecular mass cysteine proteinase inhibitor from human amniotic fluid
    Biol Chem Hoppe Seyler (1985) 366, 147-155. PubMed  Europe PubMed
    295. 1984
  295. Barrett,A.J., Davies,M.E. and Grubb,A.
    The place of human gamma-trace (cystatin C) amongst the cysteine proteinase inhibitors
    Biochem Biophys Res Commun (1984) 120, 631-636. PubMed  Europe PubMed
  296. [YEAR:13-1-1984]Brzin,J., Popovic,T., Turk,V., Borchart,U. and Machleidt,W.
    Human cystatin, a new protein inhibitor of cysteine proteinases
    Biochem Biophys Res Commun (13-1-1984) 118, 103-109. PubMed  Europe PubMed
  297. [YEAR:13-12-1984]Grubb,A., Jensson,O., Gudmundsson,G., Arnason,A., Lofberg,H. and Malm,J.
    Abnormal metabolism of gamma-trace alkaline microprotein. The basic defect in hereditary cerebral hemorrhage with amyloidosis
    N Engl J Med (13-12-1984) 311, 1547-1549. PubMed  Europe PubMed DOI
  298. Grubb,A., Lofberg,H. and Barrett,A.J.
    The disulphide bridges of human cystatin C (gamma-trace) and chicken cystatin
    FEBS Lett (1984) 170, 370-374. DOI
  299. Hirado,M., Niinobe,M. and Fujii,S.
    Purification and characterization of a bovine colostrum low molecular weight cysteine proteinase inhibitor
    J Biochem (1984) 96, 51-58. PubMed  Europe PubMed
    300. 1983
  300. [YEAR:1-8-1983]Cohen,D.H., Feiner,H., Jensson,O. and Frangione,B.
    Amyloid fibril in hereditary cerebral hemorrhage with amyloidosis (HCHWA) is related to the gastroentero-pancreatic neuroendocrine protein, gamma trace
    J Exp Med (1-8-1983) 158, 623-628. PubMed  Europe PubMed  PMC  EPMC
  301. Grubb,A.O., Weiber,H. and Lofberg,H.
    The gamma-trace concentration of normal human seminal plasma is thirty-six times that of normal human blood plasma
    Scand J Clin Lab Invest (1983) 43, 421-425. PubMed  Europe PubMed DOI
    302. 1982
  302. Grubb,A. and Lofberg,H.
    Human gamma-trace, a basic microprotein: amino acid sequence and presence in the adenohypophysis
    Proc Natl Acad Sci U S A (1982) 79, 3024-3027. PubMed  Europe PubMed  PMC  EPMC
  303. [YEAR:8-4-1982]Sekine,T. and Poulik,M.D.
    Post-gamma globulin : tissue distribution and physicochemical characteristics of dog post-gamma globulin
    Clin Chim Acta (8-4-1982) 120, 225-235. PubMed  Europe PubMed DOI
    304. 1981
  304. Poulik,M.D., Shinnick,C.S. and Smithies,O.
    Partial amino acid sequences of human and dog post-gamma globulins
    Mol Immunol (1981) 18, 569-572. PubMed  Europe PubMed DOI
    305. 1980
  305. Lofberg,H., Grubb,A.O., Sveger,T. and Olsson,J.E.
    The cerebrospinal fluid and plasma concentrations of gamma-trace and beta2-microglobulin at various ages and in neurological disorders
    J Neurol (1980) 223, 159-170. PubMed  Europe PubMed
  306. Taniguchi,K., Ito,J. and Sasaki,M.
    Partial purification and properties of urinary thiol proteinase inhibitors
    J Biochem (1980) 89, 179-184.
    307. 1979
  307. Lofberg,H. and Grubb,A.O.
    Quantitation of gamma-trace in human biological fluids: indications for production in the central nervous system
    Scand J Clin Lab Invest (1979) 39, 619-626. PubMed  Europe PubMed DOI
  308. [YEAR:14-2-1979]Tonnelle,C., Colle,A., Fougereau,M. and Manuel,Y.
    Partial amino acid sequence of two forms of human post-gamma-globulin
    Biochem Biophys Res Commun (14-2-1979) 86, 613-619. PubMed  Europe PubMed
    309. 1973
  309. Cejka,J. and Fleischmann,L.E.
    Post-gamma-globulin: isolation and physicochemical characterization
    Arch Biochem Biophys (1973) 157, 168-176. PubMed  Europe PubMed
    310. 1965
  310. MacPherson,C.F.
    Quantitative estimation of the gamma c-globulin in normal and pathological cerebrospinal fluids by an immunochemical method
    Clin Chim Acta (1965) 11, 298-309. PubMed  Europe PubMed
    311. 1962
  311. Hochwald,G.M. and Thorbecke,G.J.
    Use of an antiserum against cerebrospinal fluid in demonstration of trace proteins in biological fluids
    Proc Soc Exp Biol Med (1962) 109, 91-95. PubMed  Europe PubMed
    312. 1961
  312. Butler,E.A. and Flynn,F.V.
    The occurrence of post-gamma protein in urine: a new protein abnormality
    J Clin Pathol (1961) 14, 172-178. PubMed  Europe PubMed  PMC  EPMC
  313. Clausen,J.
    Proteins in normal cerebrospinal fluid not found in serum
    Proc Soc Exp Biol Med (1961) 107, 170-172. PubMed  Europe PubMed
  314. MacPherson,C.F. and Cosgrove,J.B.
    Immunochemical evidence for a gamma globulin peculiar to cerebrospinal fluid
    Can J Biochem Physiol (1961) 39, 1567-1574. PubMed  Europe PubMed

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