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Literature for family I14 unassigned peptidases

Summary Sequences Sequence features Distribution Literature

(Topics flags: S Structure, I Inhibitor, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. VanderPluym,C.J., Cantor,R.S., Machado,D., Boyle,G., May,L., Griffiths,E., Niebler,R.A., Lorts,A., Rossano,J., Sutcliffe,D.L., Lytrivi,I.D., Buchholz,H., Fynn-Thompson,F., Hawkins,B. and Conway,J.
    Utilization and Outcomes of Children Treated with Direct Thrombin Inhibitors on Paracorporeal Ventricular Assist Device Support
    ASAIO J (2020) 66, 939-945. PubMed  Europe PubMed DOI  V  I
    2. 2016
  2. Esteve-Pastor,M.A., Hernandez-Romero,D., Valdes,M. and Marin,F.
    New approaches to the role of thrombin in acute coronary syndromes: quo vadis bivalirudin, a direct thrombin inhibitor?
    Molecules (2016) 21, 284-284. PubMed  Europe PubMed DOI
    3. 2013
  3. Yamada,T., Kurihara,K., Ohnishi,Y., Tamada,T., Tomoyori,K., Masumi,K., Tanaka,I., Kuroki,R. and Niimura,N.
    Neutron and X-ray crystallographic analysis of the human alpha-thrombin-bivalirudin complex at pD 5.0: Protonation states and hydration structure of the enzyme-product complex
    Biochim Biophys Acta (2013) 1834, 1532-1538. PubMed  Europe PubMed DOI  S
    4. 2012
  4. Ahrens,I. and Bode,C.
    New parenteral anticoagulants: focus on factor Xa and thrombin inhibitors
    Curr Drug Discov Technol (2012) 9, 129-136. PubMed  Europe PubMed  I
    5. 2011
  5. Kimmelstiel,C., Zhang,P., Kapur,N.K., Weintraub,A., Krishnamurthy,B., Castaneda,V., Covic,L. and Kuliopulos,A.
    Bivalirudin is a dual inhibitor of thrombin and collagen-dependent platelet activation in patients undergoing percutaneous coronary intervention
    Circ Cardiovasc Interv (2011) 4, 171-179. PubMed  Europe PubMed DOI  U
    6. 2007
  6. Butenas,S., Orfeo,T., Brummel-Ziedins,K.E. and Mann,K.G.
    Influence of bivalirudin on tissue factor-triggered coagulation
    Blood Coagul Fibrinolysis (2007) 18, 407-414. PubMed  Europe PubMed DOI
    7. 2006
  7. Serruys,P.W., Vranckx,P. and Allikmets,K.
    Clinical development of bivalirudin (Angiox): rationale for thrombin-specific anticoagulation in percutaneous coronary intervention and acute coronary syndromes
    Int J Clin Pract (2006) 60, 344-350. PubMed  Europe PubMed DOI
  8. [YEAR:1-1-2006]Shen,G.X.
    Inhibition of thrombin: relevance to anti-thrombosis strategy
    Front Biosci (1-1-2006) 11, 113-120. PubMed  Europe PubMed DOI  I
    9. 2005
  9. Shammas,N.W.
    Complications in peripheral vascular interventions: emerging role of direct thrombin inhibitors
    J Vasc Interv Radiol (2005) 16, 165-171. PubMed  Europe PubMed DOI  I
    10. 2004
  10. Greinacher,A.
    Lepirudin: a bivalent direct thrombin inhibitor for anticoagulation therapy
    Expert Rev Cardiovasc Ther (2004) 2, 339-357. PubMed  Europe PubMed DOI
  11. Nutescu,E.A. and Wittkowsky,A.K.
    Direct thrombin inhibitors for anticoagulation
    Ann Pharmacother (2004) 38, 99-109. PubMed  Europe PubMed DOI  I
  12. Warkentin,T.E.
    Bivalent direct thrombin inhibitors: hirudin and bivalirudin
    Best Pract Res Clin Haematol (2004) 17, 105-125. PubMed  Europe PubMed DOI
    13. 2003
  13. [YEAR:20-9-2003]Kikelj,D.
    Peptidomimetic thrombin inhibitors
    Pathophysiol Haemost Thromb (20-9-2003) 33, 487-491. PubMed  Europe PubMed DOI  I
    14. 2002
  14. Chew,D.P.
    Bivalirudin, a bivalent, thrombin specific anticoagulant as an alternative to heparin in interventional procedures as an alternative to heparin in interventional procedures
    Hamostaseologie (2002) 22, 60-66. PubMed  Europe PubMed DOI
  15. Gladwell,T.D.
    Bivalirudin: a direct thrombin inhibitor
    Clin Ther (2002) 24, 38-58. PubMed  Europe PubMed DOI
  16. Seybert,A.L.
    Bivalirudin administration during percutaneous coronary intervention: emphasis on high-risk patients
    Pharmacotherapy (2002) 22, 112S-118S. PubMed  Europe PubMed
  17. [YEAR:1-5-2002]Weitz,J.I. and Crowther,M.
    Direct thrombin inhibitors
    Thromb Res (1-5-2002) 106, V275-V284. PubMed  Europe PubMed DOI
  18. Wiggins,B.S., Spinler,S., Wittkowsky,A.K. and Stringer,K.A.
    Bivalirudin: a direct thrombin inhibitor for percutaneous transluminal coronary angioplasty
    Pharmacotherapy (2002) 22, 1007-1018. PubMed  Europe PubMed
    19. 2001
  19. Antman,E.M. and Braunwald,E.
    A second look at bivalirudin
    Am Heart J (2001) 142, 929-931. PubMed  Europe PubMed DOI
  20. Nawarskas,J.J. and Anderson,J.R.
    Bivalirudin: a new approach to anticoagulation
    Heart Dis (2001) 3, 131-137. PubMed  Europe PubMed
    21. 2000
  21. Bates,S.M. and Weitz,J.I.
    The mechanism of action of thrombin inhibitors
    J Invasive Cardiol (2000) 12 Suppl F, 27F-32F. PubMed  Europe PubMed
    22. 1998
  22. De Simone,G., Lombardi,A., Galdiero,S., Nastri,F., Della Morte,R., Staiano,N., Pedone,C., Bolognesi,M. and Pavone,V.
    Hirunorms are true hirudin mimetics. The crystal structure of human alpha-thrombin-hirunorm V complex
    Protein Sci (1998) 7, 243-253. PubMed  Europe PubMed DOI  PMC  EPMC  S
  23. Finkle,C.D., St Pierre,A., Leblond,L., Deschenes,I., DiMaio,J. and Winocour,P.D.
    BCH-2763, a novel potent parenteral thrombin inhibitor, is an effective antithrombotic agent in rodent models of arterial and venous thrombosis - comparisons with heparin, r-hirudin, hirulog, inogatran and argatroban
    Thromb Haemost (1998) 79, 431-438. PubMed  Europe PubMed  I
    24. 1996
  24. [YEAR:25-10-1996]Cappiello,M., Vilardo,P.G., Lippi,A., Criscuoli,M., Del Corso,A. and Mura,U.
    Kinetics of human thrombin inhibition by two novel peptide inhibitors (Hirunorm IV and Hirunorm V)
    Biochem Pharmacol (25-10-1996) 52, 1141-1146. PubMed  Europe PubMed DOI
    25. 1994
  25. Johnson,P.H.
    Hirudin: clinical potential of a thrombin inhibitor
    Annu Rev Med (1994) 45, 165-177. PubMed  Europe PubMed DOI
  26. [YEAR:13-12-1994]Parry,M.A., Maraganore,J.M. and Stone,S.R.
    Kinetic mechanism for the interaction of Hirulog with thrombin
    Biochemistry (13-12-1994) 33, 14807-14814. PubMed  Europe PubMed
    27. 1992
  27. Fenton,J.W.
    Leeches to hirulogs and other thrombin-directed antithrombotics
    Hematol Oncol Clin North Am (1992) 6, 1121-1129. PubMed  Europe PubMed  V
  28. [YEAR:1-5-1992]Ofosu,F.A., Fenton,J.W., Maraganore,J., Blajchman,M.A., Yang,X., Smith,L., Anvari,N., Buchanan,M.R. and Hirsh,J.
    Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of alpha-thrombin
    Biochem J (1-5-1992) 283, 893-897. PubMed  Europe PubMed  PMC  EPMC
  29. [YEAR:1-5-1992]Witting,J.I., Bourdon,P., Brezniak,D.V., Maraganore,J.M. and Fenton,J.W.
    Thrombin-specific inhibition by and slow cleavage of hirulog-1
    Biochem J (1-5-1992) 283, 737-743. PubMed  Europe PubMed  PMC  EPMC

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