Literature for inhibitor I12.002: sunflower cyclic trypsin inhibitor

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, P Specificity, I Inhibitor, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. de Veer,S.J., White,A.M. and Craik,D.
    Sunflower Trypsin Inhibitor-1 (SFTI-1): Sowing Seeds in the Fields of Chemistry and Biology
    Angew Chem Int Ed Engl PubMed  Europe PubMed DOI  V
  2. Li,C.Y., Yap,K., Swedberg,J.E., Craik,D.J. and de Veer,S.J.
    Binding loop substitutions in the cyclic peptide SFTI-1 generate potent and selective chymase inhibitors
    J Med Chem63, 816-826. PubMed  Europe PubMed DOI
  3. 2019
  4. Chen,X., Riley,B.T., de Veer,S.J., Hoke,D.E., Van Haeften,J., Leahy,D., Swedberg,J.E., Brattsand,M., Hartfield,P.J., Buckle,A.M. and Harris,J.M.
    Potent, multi-target serine protease inhibition achieved by a simplified beta-sheet motif
    PLoS ONE14, e0210842-e0210842. PubMed  Europe PubMed DOI  S
  5. Kiryutin,A.S., Sauer,G., Tietze,D., Brodrecht,M., Knecht,S., Yurkovskaya,A.V., Ivanov,K.L., Avrutina,O., Kolmar,H. and Buntkowsky,G.
    Ultrafast single-scan 2D NMR spectroscopic detection of a PHIP-hyperpolarized protease inhibitor
    Chemistry25, 4025-4030. PubMed  Europe PubMed DOI
  6. Li,C.Y., de Veer,S.J., White,A.M., Chen,X., Harris,J.M., Swedberg,J.E. and Craik,D.J.
    Amino acid scanning at P5' within the Bowman-Birk inhibitory loop reveals specificity trends for diverse serine proteases
    J Med Chem62, 3696-3706. PubMed  Europe PubMed DOI
  7. Pouvreau,B., Fenske,R., Ivanova,A., Murcha,M.W. and Mylne,J.S.
    An interstitial peptide is readily processed from within seed proteins
    Plant Sci285, 175-183. PubMed  Europe PubMed DOI
  8. Riley,B.T., Ilyichova,O., de Veer,S.J., Swedberg,J.E., Wilson,E., Hoke,D.E., Harris,J.M. and Buckle,A.M.
    KLK4 Inhibition by cyclic and acyclic peptides: structural and dynamical insights into standard-mechanism protease inhibitors
    Biochemistry58, 2524-2533. PubMed  Europe PubMed DOI
  9. Swedberg,J.E., Wu,G., Mahatmanto,T., Durek,T., Caradoc-Davies,T.T., Whisstock,J.C., Law,R.H.P. and Craik,D.J.
    Highly potent and selective plasmin inhibitors based on the sunflower trypsin inhibitor-1 scaffold attenuate fibrinolysis in plasma
    J Med Chem62, 552-560. PubMed  Europe PubMed DOI
  10. Tian,S., Swedberg,J.E., Li,C.Y., Craik,D.J. and de Veer,S.J.
    Iterative optimization of the cyclic peptide SFTI-1 yields potent inhibitors of neutrophil proteinase 3
    ACS Med Chem Lett10, 1234-1239. PubMed  Europe PubMed DOI
  11. 2018
  12. de Veer,S.J., Li,C.Y., Swedberg,J.E., Schroeder,C.I. and Craik,D.J.
    Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1
    Eur J Med Chem155, 695-704. PubMed  Europe PubMed DOI
  13. Quintero,D., Carrafa,J., Vincent,L., Lee,H.J., Wohlschlegel,J. and Bermudes,D.
    Co-expression of a chimeric protease inhibitor secreted by a tumor-targeted Salmonella protects therapeutic proteins from proteolytic degradation
    J Microbiol Biotechnol28, 2079-2094. PubMed  Europe PubMed DOI  U
  14. 2017
  15. Franke,B., James,A.M., Mobli,M., Colgrave,M.L., Mylne,J.S. and Rosengren,K.J.
    Two proteins for the price of one: structural studies of the dual-destiny protein preproalbumin with sunflower trypsin inhibitor-1
    J Biol Chem292, 12398-12411. PubMed  Europe PubMed DOI
  16. Gitlin-Domagalska,A., Debowski,D., Legowska,A., Stirnberg,M., Okonska,J., Gutschow,M. and Rolka,K.
    Design and chemical syntheses of potent matriptase-2 inhibitors based on trypsin inhibitor SFTI-1 isolated from sunflower seeds
    Biopolymers108, PubMed  Europe PubMed DOI  I
  17. Jayasena,A.S., Fisher,M.F., Panero,J.L., Secco,D., Bernath-Levin,K., Berkowitz,O., Taylor,N.L., Schilling,E.E., Whelan,J. and Mylne,J.S.
    Stepwise evolution of a buried inhibitor peptide over 45 My
    Mol Biol Evol34, 1505-1516. PubMed  Europe PubMed DOI
  18. Swedberg,J.E., Li,C.Y., de Veer,S.J., Wang,C.K. and Craik,D.J.
    Design of potent and selective cathepsin G inhibitors based on the sunflower trypsin inhibitor-1 scaffold
    J Med Chem60, 658-667. PubMed  Europe PubMed DOI  P
  19. 2016
  20. Chen,W., Kinsler,V.A., Macmillan,D. and Di,W.L.
    Tissue kallikrein inhibitors based on the sunflower trypsin inhibitor scaffold - a potential therapeutic intervention for skin diseases
    PLoS ONE11, e0166268-e0166268. PubMed  Europe PubMed DOI
  21. Debowski,D., Cichorek,M., Lubos,M., Wojcik,S., Legowska,A. and Rolka,K.
    Noncovalent inhibitors of human 20S and 26S proteasome based on trypsin inhibitor SFTI-1
    Biopolymers106, 685-696. PubMed  Europe PubMed DOI  I
  22. Filipowicz,M., Ptaszynska,N., Olkiewicz,K., Debowski,D., Cwiklowska,K., Burster,T., Pikula,M., Krzystyniak,A., Legowska,A. and Rolka,K.
    Spliced analogues of trypsin inhibitor SFTI-1 and their application for tracing proteolysis and delivery of cargos inside the cells
    Biopolymers108, PubMed  Europe PubMed DOI
  23. Kuznetsova,S.S., Kolesanova,E.F., Talanova,A.V. and Veselovsky,A.V.
    [Prospects for the design of new therapeutically significant protease inhibitors based on knottins & sunflower seed trypsin inhibitor (SFTI 1)]
    Biomeditsinskaya Khim62, 353-368. PubMed  Europe PubMed DOI
  24. Riley,B.T., Ilyichova,O., Costa,M.G., Porebski,B.T., de Veer,S.J., Swedberg,J.E., Kass,I., Harris,J.M., Hoke,D.E. and Buckle,A.M.
    Direct and indirect mechanisms of KLK4 inhibition revealed by structure and dynamics
    Sci Rep6, 35385-35385. PubMed  Europe PubMed DOI  S
  25. 2015
  26. Bernath-Levin,K., Nelson,C., Elliott,A.G., Jayasena,A.S., Millar,A.H., Craik,D.J. and Mylne,J.S.
    Peptide macrocyclization by a bifunctional endoprotease
    Chem Biol22, 571-582. PubMed  Europe PubMed DOI
  27. de Veer,S.J., Wang,C.K., Harris,J.M., Craik,D.J. and Swedberg,J.E.
    Improving the selectivity of engineered protease inhibitors: optimizing the P2 prime residue using a versatile cyclic peptide library
    J Med Chem58, 8257-8268. PubMed  Europe PubMed DOI
  28. de Veer,S.J., Swedberg,J.E., Akcan,M., Rosengren,K.J., Brattsand,M., Craik,D.J. and Harris,J.M.
    Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition
    Biochem J469, 243-253. PubMed  Europe PubMed DOI
  29. Fittler,H., Depp,A., Avrutina,O., Dahms,S.O., Than,M.E., Empting,M. and Kolmar,H.
    Engineering a constrained peptidic scaffold towards potent and selective furin inhibitors
    Chembiochem16, 2441-2444. PubMed  Europe PubMed DOI
  30. Gitlin,A., Debowski,D., Karna,N., Legowska,A., Stirnberg,M., Gutschow,M. and Rolka,K.
    Inhibitors of matriptase-2 based on the trypsin inhibitor SFTI-1
    Chembiochem16, 1601-1607. PubMed  Europe PubMed DOI
  31. Karna,N., Debowski,D., Legowska,A., Bachor,R., Szewczuk,Z. and Rolka,K.
    Peptide splicing in a double-sequence analogue of trypsin inhibitor SFTI-1 substituted in the P(1) positions by peptoid monomers
    Biopolymers104, 206-212. PubMed  Europe PubMed DOI
  32. 2014
  33. Chen,Y.-Q., Chen,C.-C., He,Y., Yu,M., Xu,L., Tian,C.-L., Guo,Q.-X., Shi,J., Zhang,M. and Li,Y.-M.
    Efficient synthesis of trypsin inhibitor SFTI-1 via intramolecular ligation of peptide hydrazide
    Tetrahedron Lett55, 2883-2886. DOI
  34. Debowski,D., Pikula,M., Lubos,M., Langa,P., Trzonkowski,P., Lesner,A., Legowska,A. and Rolka,K.
    Inhibition of human and yeast 20S proteasome by analogues of trypsin inhibitor SFTI-1
    PLoS ONE9, e89465-e89465. PubMed  Europe PubMed DOI
  35. Elliott,A.G., Delay,C., Liu,H., Phua,Z., Rosengren,K.J., Benfield,A.H., Panero,J.L., Colgrave,M.L., Jayasena,A.S., Dunse,K.M., Anderson,M.A., Schilling,E.E., Ortiz-Barrientos,D., Craik,D.J. and Mylne,J.S.
    Evolutionary origins of a bioactive peptide buried within preproalbumin
    Plant Cell26, 981-995. PubMed  Europe PubMed DOI
  36. Fittler,H., Avrutina,O., Empting,M. and Kolmar,H.
    Potent inhibitors of human matriptase-1 based on the scaffold of sunflower trypsin inhibitor
    J Pept Sci20, 415-420. PubMed  Europe PubMed DOI  I
  37. Krzywda,S., Jaskolski,M., Rolka,K. and Stawikowski,M.J.
    Structure of a proteolytically resistant analogue of (NLys)5SFTI-1 in complex with trypsin: evidence for the direct participation of the Ser214 carbonyl group in serine protease-mediated proteolysis
    Acta Crystallogr D Biol Crystallogr70, 668-675. PubMed  Europe PubMed DOI  S
  38. Lesner,A., Karna,N., Psurski,M., Legowska,A., Wysocka,M., Guzow,K., Sieradzan,A., Sienczyk,M., Trzonkowski,P., Pikula,M., Zielinski,M., Kosikowska,P., Lukajtis,R., Legowska,M., Debowski,D., Wiczk,W. and Rolka,K.
    Fluorescent analogs of trypsin inhibitor SFTI-1 isolated from sunflower seeds - synthesis and applications
    Biopolymers102, 124-135. PubMed  Europe PubMed DOI
  39. Shariff,L., Zhu,Y., Cowper,B., Di,W.-L. and Macmillan,D.
    Sunflower trypsin inhibitor (SFTI-1) analogues of synthetic and biological origin via N-->S acyl transfer: potential inhibitors of human kallikrein-5 (KLK5)
    Tetrahedron70, 7675-7680. DOI
  40. 2013
  41. de Veer,S.J., Ukolova,S.S., Munro,C.A., Swedberg,J.E., Buckle,A.M. and Harris,J.M.
    Mechanism-based selection of a potent kallikrein-related peptidase 7 inhibitor from a versatile library based on the sunflower trypsin inhibitor SFTI-1
    Biopolymers100, 510-518. PubMed  Europe PubMed DOI
  42. Fittler,H., Avrutina,O., Glotzbach,B., Empting,M. and Kolmar,H.
    Combinatorial tuning of peptidic drug candidates: high-affinity matriptase inhibitors through incremental structure-guided optimization
    Org Biomol Chem11, 1848-1857. PubMed  Europe PubMed DOI  I
  43. Karna,N., Debowski,D., Gitlin,A., Legowska,A. and Rolka,K.
    Investigation of peptide splicing using two-peptide-chain analogs of trypsin inhibitor SFTI-1
    FEBS J280, 6213-6222. PubMed  Europe PubMed DOI
  44. Quimbar,P., Malik,U., Sommerhoff,C.P., Kaas,Q., Chan,L.Y., Huang,Y.H., Grundhuber,M., Dunse,K., Craik,D.J., Anderson,M.A. and Daly,N.L.
    High-affinity cyclic peptide matriptase inhibitors
    J Biol Chem288, 13885-13896. PubMed  Europe PubMed DOI
  45. 2012
  46. Avrutina,O., Fittler,H., Glotzbach,B., Kolmar,H. and Empting,M.
    Between two worlds: a comparative study on in vitro and in silico inhibition of trypsin and matriptase by redox-stable SFTI-1 variants at near physiological pH
    Org Biomol Chem10, 7753-7762. PubMed  Europe PubMed DOI
  47. Tischler,M., Nasu,D., Empting,M., Schmelz,S., Heinz,D.W., Rottmann,P., Kolmar,H., Buntkowsky,G., Tietze,D. and Avrutina,O.
    Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations
    Angew Chem Int Ed Engl51, 3708-3712. PubMed  Europe PubMed DOI
  48. 2011
  49. Kang,T.J., Hayashi,Y. and Suga,H.
    Synthesis of the backbone cyclic peptide sunflower trypsin inhibitor-1 promoted by the induced peptidyl-tRNA drop-off
    Angew Chem Int Ed Engl50, 2159-2161. PubMed  Europe PubMed DOI
  50. Legowska,A., Debowski,D., Lukajtis,R., Sztabkowska,E., Mizeria,A., Brzozowski,K., Wysocka,M., Lesner,A. and Rolka,K.
    Introduction of Pro and its analogues in the conserved P1' position of trypsin inhibitor SFTI-1 retains its inhibitory activity
    Protein Pept Lett18, 1158-1167. PubMed  Europe PubMed DOI
  51. Lesner,A., Legowska,A., Wysocka,M. and Rolka,K.
    Sunflower trypsin inhibitor 1 as a molecular scaffold for drug discovery
    Curr Pharm Des17, 4308-4317. PubMed  Europe PubMed
  52. Mylne,J.S., Colgrave,M.L., Daly,N.L., Chanson,A.H., Elliott,A.G., McCallum,E.J., Jones,A. and Craik,D.J.
    Albumins and their processing machinery are hijacked for cyclic peptides in sunflower
    Nat Chem Biol7, 257-259. PubMed  Europe PubMed DOI
  53. Rafal,L., Anna,L., Magdalena,W., Dawid,D., Adam,L. and Krzysztof,R.
    Analogues of trypsin inhibitor SFTI-1 modified in the conserved P1' position by synthetic or non-proteinogenic amino acids retain their inhibitory activity
    J Pept Sci17, 281-287. PubMed  Europe PubMed DOI
  54. Swedberg,J.E., de Veer,S.J., Sit,K.C., Reboul,C.F., Buckle,A.M. and Harris,J.M.
    Mastering the canonical loop of serine protease inhibitors: enhancing potency by optimising the internal hydrogen bond network
    PLoS ONE6, e19302-e19302. PubMed  Europe PubMed DOI
  55. Yuan,C., Chen,L., Meehan,E.J., Daly,N.L., Craik,D.J., Huang,M. and Ngo,J.C.
    Structure of catalytic domain of matriptase in complex with sunflower trypsin inhibitor-1
    BMC Struct Biol11, 30-30. PubMed  Europe PubMed DOI  S
  56. 2010
  57. Colgrave,M.L., Korsinczky,M.J., Clark,R.J., Foley,F. and Craik,D.J.
    Sunflower trypsin inhibitor-1, proteolytic studies on a trypsin inhibitor peptide and its analogs
    Biopolymers94, 665-672. PubMed  Europe PubMed DOI
  58. de Marco,R., Azzolini,S.S., Lovato,D.V., Torquato,R.J.S., Amino,R., de Miranda,A. and Tanaka,A.S.
    Validation of phage display method for protease inhibitor selection using synthetic hybrid peptides
    Comb Chem High Throughput Screen13, 829-835. PubMed  Europe PubMed DOI
  59. Garcia Boy,R., Mier,W., Nothelfer,E.M., Altmann,A., Eisenhut,M., Kolmar,H., Tomaszowski,M., Kramer,S. and Haberkorn,U.
    Sunflower trypsin inhibitor 1 derivatives as molecular scaffolds for the development of novel peptidic radiopharmaceuticals
    Mol Imaging Biol12, 377-385. PubMed  Europe PubMed DOI
  60. Kocsis,A., Kekesi,K.A., Szasz,R., Vegh,B.M., Balczer,J., Dobo,J., Zavodszky,P., Gal,P. and Pal,G.
    Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and -2: significant contribution of MASP-1 to lectin pathway activation
    J Immunol185, 4169-4178. PubMed  Europe PubMed DOI  I
  61. Legowska,A., Debowski,D., Lukajtis,R., Wysocka,M., Czaplewski,C., Lesner,A. and Rolka,K.
    Implication of the disulfide bridge in trypsin inhibitor SFTI-1 in its interaction with serine proteinases
    Bioorg Med Chem18, 8188-8193. PubMed  Europe PubMed DOI
  62. Legowska,A., Bulak,E., Jaskiewicz,A., Maluch,I., Sieracki,M., Wysocka,M., Lesner,A. and Rolka,K.
    Analogues of trypsin inhibitor SFTI-1 with disulfide bridge substituted by various length of carbonyl bridges
    Protein Pept Lett17, 1223-1227. PubMed  Europe PubMed DOI
  63. Legowska,A., Lesner,A., Bulak,E., Jaskiewicz,A., Sieradzan,A., Cydzik,M., Stefanowicz,P., Szewczuk,Z. and Rolka,K.
    Inhibitory activity of double-sequence analogues of trypsin inhibitor SFTI-1 from sunflower seeds: an example of peptide splicing
    FEBS J277, 2351-2359. PubMed  Europe PubMed DOI
  64. Legowska,A., Debowski,D., Lesner,A., Wysocka,M. and Rolka,K.
    Selection of peptomeric inhibitors of bovine alpha-chymotrypsin and cathepsin G based on trypsin inhibitor SFTI-1 using a combinatorial chemistry approach
    Mol Divers14, 51-58. PubMed  Europe PubMed DOI  I
  65. 2009
  66. Legowska,A., Debowski,D., Lesner,A., Wysocka,M. and Rolka,K.
    Introduction of non-natural amino acid residues into the substrate-specific P1 position of trypsin inhibitor SFTI-1 yields potent chymotrypsin and cathepsin G inhibitors
    Bioorg Med Chem17, 3302-3307. PubMed  Europe PubMed DOI
  67. Pereira,H.J., Salgado,M.C. and Oliveira,E.B.
    Immobilized analogues of sunflower trypsin inhibitor-1 constitute a versatile group of affinity sorbents for selective isolation of serine proteases
    J Chromatogr B Analyt Technol Biomed Life Sci877, 2039-2044. PubMed  Europe PubMed DOI
  68. 2008
  69. Legowska,A., Bulak,E., Wysocka,M., Jaskiewicz,A., Lesner,A., Debowski,D. and Rolka,K.
    Peptomeric analogues of trypsin inhibitor SFTI-1 isolated from sunflower seeds
    Bioorg Med Chem16, 5644-5652. PubMed  Europe PubMed DOI
  70. 2007
  71. [YEAR:4-1-2007]Jiang,S., Li,P., Lee,S.L., Lin,C.Y., Long,Y.Q., Johnson,M.D., Dickson,R.B. and Roller,P.P.
    Design and synthesis of redox stable analogues of sunflower trypsin inhibitors (SFTI-1) on solid support, potent inhibitors of matriptase
    Org Lett9, 9-12. PubMed  Europe PubMed DOI
  72. Li,P., Jiang,S., Lee,S.L., Lin,C.Y., Johnson,M.D., Dickson,R.B., Michejda,C.J. and Roller,P.P.
    Design and synthesis of novel and potent inhibitors of the type II transmembrane serine protease, matriptase, based upon the sunflower trypsin inhibitor-1
    J Med Chem50, 5976-5983. PubMed  Europe PubMed DOI  I
  73. Zablotna,E., Jaskiewicz,A., Legowska,A., Miecznikowska,H., Lesner,A. and Rolka,K.
    Design of serine proteinase inhibitors by combinatorial chemistry using trypsin inhibitor SFTI-1 as a starting structure
    J Pept Sci13, 749-755. PubMed  Europe PubMed DOI
  74. 2006
  75. [YEAR:9-6-2006]Daly,N.L., Chen,Y.K., Foley,F.M., Bansal,P.S., Bharathi,R., Clark,R.J., Sommerhoff,C.P. and Craik,D.J.
    The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold
    J Biol Chem281, 23668-23675. PubMed  Europe PubMed DOI
  76. Guo,X., Shi,J., Tang,Z., Cui,D. and Zhang,Y.
    Synthesis and biological activity of seleno sunflower trypsin inhibitor analog
    Chem Biol Drug Des68, 341-344. PubMed  Europe PubMed DOI
  77. [YEAR:20-12-2006]Zablotna,E., Kret,A., Jaskiewicz,A., Olma,A., Leplawy,M.T. and Rolka,K.
    Introduction of alpha-hydroxymethyamino acid residues in substrate specificity P1 position of trypsin inhibitor SFTI-1 from sunflower seeds retains its activity
    Biochem Biophys Res Commun340, 823-828. PubMed  Europe PubMed DOI
  78. 2005
  79. Hilpert,K., Hansen,G., Wessner,H., Volkmer-Engert,R. and Hohne,W.
    Complete substitutional analysis of a sunflower trypsin inhibitor with different serine proteases
    J Biochem138, 383-390. PubMed  Europe PubMed DOI
  80. Jaulent,A.M., Brauer,A.B., Matthews,S.J. and Leatherbarrow,R.J.
    Solution structure of a novel C2-symmetrical bifunctional bicyclic inhibitor based on SFTI-1
    J Biomol NMR33, 57-62. PubMed  Europe PubMed DOI
  81. [YEAR:1-2-2005]Korsinczky,M.L., Clark,R.J. and Craik,D.J.
    Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1
    Biochemistry44, 1145-1153. PubMed  Europe PubMed DOI
  82. [YEAR:21-7-2005]Mulvenna,J.P., Foley,F.M. and Craik,D.J.
    Discovery, structural determination, and putative processing of the precursor protein that produces the cyclic trypsin inhibitor sunflower trypsin inhibitor 1
    J Biol Chem280, 32245-32253. PubMed  Europe PubMed DOI
  83. [YEAR:10-5-2005]Stawikowski,M., Stawikowska,R., Jaskiewicz,A., Zablotna,E. and Rolka,K.
    Examples of peptide-peptoid hybrid serine protease inhibitors based on the trypsin inhibitor SFTI-1 with complete protease resistance at the P1 - P1' reactive site
    Chembiochem6, 1057-1061. PubMed  Europe PubMed DOI
  84. 2004
  85. Korsinczky,M.L., Schirra,H.J. and Craik,D.J.
    Sunflower trypsin inhibitor-1
    Curr Protein Pept Sci5, 351-364. PubMed  Europe PubMed DOI
  86. 2003
  87. [YEAR:13-6-2003]Marx,U.C., Korsinczky,M.L., Schirra,H.J., Jones,A., Condie,B., Otvos,L., Jr. and Craik,D.J.
    Enzymatic cyclization of a potent Bowman-Birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide
    J Biol Chem278, 21782-21789. PubMed  Europe PubMed DOI
  88. 2002
  89. Descours,A., Moehle,K., Renard,A. and Robinson,J.A.
    A new family of beta-hairpin mimetics based on a trypsin inhibitor from sunflower seeds
    Chembiochem3, 318-323. PubMed  Europe PubMed DOI
  90. McBride,J.D., Watson,E.M., Brauer,A.B., Jaulent,A.M. and Leatherbarrow,R.J.
    Peptide mimics of the Bowman-Birk inhibitor reactive site loop
    Biopolymers66, 79-92. PubMed  Europe PubMed DOI  I
  91. [YEAR:12-4-2002]Zablotna,E., Kazmierczak,K., Jaskiewicz,A., Stawikowski,M., Kupryszewski,G. and Rolka,K.
    Chemical synthesis and kinetic study of the smallest naturally occurring trypsin inhibitor SFTI-1 isolated from sunflower seeds and its analogues
    Biochem Biophys Res Commun292, 855-859. PubMed  Europe PubMed DOI
  92. 2001
  93. [YEAR:17-8-2001]Korsinczky,M.L.J., Schirra,H.J., Rosengren,K.J., West,J., Condie,B.A., Otvos,L., Anderson,M.A. and Craik,D.J.
    Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant
    J Mol Biol311, 579-591. PubMed  Europe PubMed DOI
  94. [YEAR:17-9-2001]Long,Y.Q., Lee,S.L., Lin,C.Y., Enyedy,I.J., Wang,S., Li,P., Dickson,R.B. and Roller,P.P.
    Synthesis and evaluation of the sunflower derived trypsin inhibitor as a potent inhibitor of the type II transmembrane serine protease, matriptase
    Bioorg Med Chem Lett11, 2515-2519. PubMed  Europe PubMed DOI
  95. 1999
  96. [YEAR:9-7-1999]Luckett,S., Garcia,R.S., Barker,J.J., Konarev,A.V., Shewry,P.R., Clarke,A.R. and Brady,R.L.
    High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds
    J Mol Biol290, 525-533. PubMed  Europe PubMed DOI  S