Literature for inhibitor I07.004: macrocyclic squash trypsin inhibitor (Momordica cochinchinensis)
(Topics flags: S Structure, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)
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Mishra,M., Singh,V., Tellis,M.B., Joshi,R.S. and Singh,S.
Repurposing the McoTI-II Rigid Molecular Scaffold in to Inhibitor of 'Papain Superfamily' Cysteine Proteases
Pharmaceuticals (Basel)14, PubMed Europe PubMed DOI -
Jones,P.M., Mazzio,E., Soliman,K. and George,A.M.
In silico investigation of the binding of MCoTI-II plant defense knottin to the gamma-NGF serine protease of the 7S nerve growth factor complex and biological activity of its NGF mimetic properties
J Phys Chem B123, 9104-9110. PubMed Europe PubMed DOI -
Swedberg,J.E., Ghani,H.A., Harris,J.M., de Veer,S.J. and Craik,D.J.
Potent, selective, and cell-penetrating inhibitors of kallikrein-related peptidase 4 based on the cyclic peptide MCoTI-II
ACS Med Chem Lett9, 1258-1262. PubMed Europe PubMed DOI -
Jones,P.M. and George,A.M.
Computational analysis of the MCoTI-II plant defence knottin reveals a novel intermediate conformation that facilitates trypsin binding
Sci Rep6, 23174-23174. PubMed Europe PubMed DOI S -
Swedberg,J.E., Mahatmanto,T., Abdul Ghani,H., de Veer,S.J., Schroeder,C.I., Harris,J.M. and Craik,D.J.
Substrate-guided design of selective FXIIa inhibitors based on the plant-derived Momordica cochinchinensis trypsin inhibitor-II (MCoTI-II) scaffold
J Med Chem59, 7287-7292. PubMed Europe PubMed DOI -
Gray,K., Elghadban,S., Thongyoo,P., Owen,K.A., Szabo,R., Bugge,T.H., Tate,E.W., Leatherbarrow,R.J. and Ellis,V.
Potent and specific inhibition of the biological activity of the type-II transmembrane serine protease matriptase by the cyclic microprotein MCoTI-II
Thromb Haemost112, 402-411. PubMed Europe PubMed DOI -
Reinwarth,M., Avrutina,O., Fabritz,S. and Kolmar,H.
Fragmentation follows structure: top-down mass spectrometry elucidates the topology of engineered cystine-knot miniproteins
PLoS ONE9, e108626-e108626. PubMed Europe PubMed DOI -
Daly,N.L., Thorstholm,L., Greenwood,K.P., King,G.J., Rosengren,K.J., Heras,B., Martin,J.L. and Craik,D.J.
Structural insights into the role of the cyclic backbone in a squash trypsin inhibitor
J Biol Chem288, 36141-36148. PubMed Europe PubMed DOI -
Glotzbach,B., Reinwarth,M., Weber,N., Fabritz,S., Tomaszowski,M., Fittler,H., Christmann,A., Avrutina,O. and Kolmar,H.
Combinatorial optimization of cystine-knot peptides towards high-affinity inhibitors of human matriptase-1
PLoS ONE8, e76956-e76956. PubMed Europe PubMed DOI -
Quimbar,P., Malik,U., Sommerhoff,C.P., Kaas,Q., Chan,L.Y., Huang,Y.H., Grundhuber,M., Dunse,K., Craik,D.J., Anderson,M.A. and Daly,N.L.
High-affinity cyclic peptide matriptase inhibitors
J Biol Chem288, 13885-13896. PubMed Europe PubMed DOI -
Arimatsu,P. and Sawangsook,O.
Purification and characterization of trypsin inhibitor from Momordica cochinchinensis Spreng. seed and its effects to Spodoptera litura
Asian J Plant Sci11, 195-199. DOI -
Mylne,J.S., Chan,L.Y., Chanson,A.H., Daly,N.L., Schaefer,H., Bailey,T.L., Nguyencong,P., Cascales,L. and Craik,D.J.
Cyclic peptides arising by evolutionary parallelism via asparaginyl-endopeptidase-mediated biosynthesis
Plant Cell24, 2765-2778. PubMed Europe PubMed DOI -
Puttamadappa,S.S., Jagadish,K., Shekhtman,A. and Camarero,J.A.
Backbone dynamics of cyclotide MCoTI-I free and complexed with trypsin
Angew Chem Int Ed Engl49, 7030-7034. PubMed Europe PubMed DOI -
Sommerhoff,C.P., Avrutina,O., Schmoldt,H.U., Gabrijelcic-Geiger,D., Diederichsen,U. and Kolmar,H.
Engineered cystine knot miniproteins as potent inhibitors of human mast cell tryptase beta
J Mol Biol395, 167-175. PubMed Europe PubMed DOI -
Thongyoo,P., Bonomelli,C., Leatherbarrow,R.J. and Tate,E.W.
Potent inhibitors of beta-tryptase and human leukocyte elastase based on the MCoTI-II scaffold
J Med Chem52, 6197-6200. PubMed Europe PubMed DOI -
Thongyoo,P., Roque-Rosell,N., Leatherbarrow,R.J. and Tate,E.W.
Chemical and biomimetic total syntheses of natural and engineered MCoTI cyclotides
Org Biomol Chem6, 1462-1470. PubMed Europe PubMed DOI -
[YEAR:24-3-2006]Cemazar,M., Daly,N.L., Haggblad,S., Lo,K.P., Yulyaningsih,E. and Craik,D.J.
Knots in rings. The circular knotted protein Momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate
J Biol Chem281, 8224-8232. PubMed Europe PubMed DOI -
Niemann,H.H., Schmoldt,H.U., Wentzel,A., Kolmar,H. and Heinz,D.W.
Barnase fusion as a tool to determine the crystal structure of the small disulfide-rich protein McoEeTI
J Mol Biol356, 1-8. PubMed Europe PubMed DOI S -
[YEAR:21-7-2006]Thongyoo,P., Tate,E.W. and Leatherbarrow,R.J.
Total synthesis of the macrocyclic cysteine knot microprotein MCoTI-II
Chem Commun (Camb)2006, 2848-2850. PubMed Europe PubMed DOI -
Avrutina,O., Schmoldt,H.U., Gabrijelcic-Geiger,D., Le Nguyen,D., Sommerhoff,C.P., Diederichsen,U. and Kolmar,H.
Trypsin inhibition by macrocyclic and open-chain variants of the squash inhibitor MCoTI-II
Biol Chem386, 1301-1306. PubMed Europe PubMed DOI -
Chiche,L., Heitz,A., Gelly,J.C., Gracy,J., Chau,P.T., Ha,P.T., Hernandez,J.F. and Le-Nguyen,D.
Squash inhibitors: from structural motifs to macrocyclic knottins
Curr Protein Pept Sci5, 341-349. PubMed Europe PubMed DOI V -
[YEAR:22-6-2001]Felizmenio-Quimio,M.E., Daly,N.L. and Craik,D.J.
Circular proteins in plants: solution structure of a novel macrocyclic trypsin inhibitor from Momordica cochinchinensis
J Biol Chem276, 22875-22882. PubMed Europe PubMed DOI S -
[YEAR:10-7-2001]Heitz,A., Hernandez,J.F., Gagnon,J., Hong,T.T., Pham,T.T.C., Nguyen,T.M., Le Nguyen,D. and Chiche,L.
Solution structure of the squash trypsin inhibitor MCoTI-II. A new family for cyclic knottins
Biochemistry40, 7973-7983. PubMed Europe PubMed DOI S -
Pearce,J.
Going round in circles to avoid proteolysis
Trends Biochem Sci26, 282-282. PubMed Europe PubMed -
[YEAR:16-5-2000]Hernandez,J.F., Gagnon,J., Chiche,L., Nguyen,T.M., Andrieu,J.P., Heitz,A., Trinh,H.T., Pham,T.T. and Le Nguyen,D.
Squash trypsin inhibitors from Momordica cochinchinensis exhibit an atypical macrocyclic structure
Biochemistry39, 5722-5730. PubMed Europe PubMed DOI
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