Literature for family I4 unassigned peptidases

Summary Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, K Knockout, E Expression, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Batool,A., Rehman,S., Malik,S., Haider,S., Abbasi,B.A. and Akhtar,S.
    Genome-wide in-silico characterization and expression profiles of serpin gene family in foxtail millet (Setaria italica)
    Comput Biol Chem (2025) 121, 108811-108811. PubMed  Europe PubMed DOI
  2. Liang,W., Li,M., Chen,F., Wang,Y., Wang,K., Wu,C. and Zhu,J.
    A venom serpin from the assassin bug Sycanus croceovittatus exhibiting inhibitory effects on melanization, development, and insecticidal activity towards its prey
    Pestic Biochem Physiol (2025) 209, 106322-106322. PubMed  Europe PubMed DOI
  3. 2024
  4. Aggarwal,S., Vineeth,V.S., Padwal,S.S., Bhat,S.A., Singh,A., Kulkarni,A., Patil,M., Tallapaka,K., Pasumarthi,D., Venkatapuram,V., Thotakura,P.L., Dalal,A. and Bhandari,R.
    SERPINA11 related novel serpinopathy - A perinatal lethal disorder
    Clin Genet (2024) 106, 367-373. PubMed  Europe PubMed DOI
  5. Feng,H. and Jander,G.
    Serine proteinase inhibitors from Nicotiana benthamiana, a nonpreferred host plant, inhibit the growth of Myzus persicae (green peach aphid)
    Pest Manag Sci (2024) 80, 4470-4481. PubMed  Europe PubMed DOI
  6. Feng,T., Tong,H., Zhang,Q., Ming,Z., Song,Z., Zhou,X. and Dai,J.
    Targeting Haemaphysalis longicornis serpin to prevent tick feeding and pathogen transmission
    Insect Sci (2024) 31, 694-706. PubMed  Europe PubMed DOI
  7. Jiang,H., Li,H., Liu,X., Zhang,S., Li,X., Wang,L., Zhang,M., Yu,M., Li,X. and Qiao,Z.
    The identification of a serpin with immune defense role in oriental river prawn Macrobrachium nipponense
    Int J Biol Macromol (2024) 261, 129747-129747. PubMed  Europe PubMed DOI  K
  8. Kim,J.H., Park,K., Kim,W.S. and Kwak,I.S.
    Expressions of Immune Prophenoloxidase (proPO) System-Related Genes Under Oxidative Stress in the Gonads and Stomach of the Mud Crab (Macrophthalmus japonicus) Exposed to Endocrine-Disrupting Chemicals
    Antioxidants (Basel) (2024) 13 PubMed  Europe PubMed DOI  PMC  EPMC
  9. Zhen,J., Lin,L., Li,Z., Sun,F., Han,Y., Li,Q., Yang,Y., Liu,X., Yu,J., Zhang,Q., Lu,Y. and Han,C.
    Regulatory effects of Trichinella spiralis serpin-type serine protease inhibitor on endoplasmic reticulum stress and oxidative stress in host intestinal epithelial cells
    Vet Res (2024) 55, 78-78. PubMed  Europe PubMed DOI  PMC  EPMC
  10. 2023
  11. Cortez-de-la-Fuente,L.J., Garcia-Gonzalez,G., Hernandez-Bello,R., Gonzalez,G.M. and Palma-Nicolas,J.P.
    Expression of Trichinella spiralis serpin Tsp_01570 in Pichia pastoris: a first insight of its biomodulatory activity
    Parasitol Res (2023) 122, 245-255. PubMed  Europe PubMed DOI
  12. Han,X., Bi,X., Zhao,H., Shi,Y., Wen,Q., Lu,J., Sun,J., Fu,X. and Liu,D.
    [Bioinformatics analysis and prokaryotic expression of Strongyloides stercoralis serine protease inhibitor 1]
    Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi (2023) 35, 244-250. PubMed  Europe PubMed DOI
  13. Qie,X., Yan,X., Wang,W., Liu,Y., Zhang,L., Hao,C., Lu,Z. and Ma,L.
    Serpin-4 Negatively Regulates Prophenoloxidase Activation and Antimicrobial Peptide Synthesis in the Silkworm, Bombyx mori
    Int J Mol Sci (2023) 25 PubMed  Europe PubMed DOI  PMC  EPMC
  14. Varkoly,K., Beladi,R., Hamada,M., McFadden,G., Irving,J. and Lucas,A.R.
    Viral SERPINS-A Family of Highly Potent Immune-Modulating Therapeutic Proteins
    Biomolecules (2023) 13 PubMed  Europe PubMed DOI  PMC  EPMC  V
  15. Xu,J., Ye,W., Yang,T.T., Yan,T., Cai,H., Zhou,A. and Yang,Y.
    DNA accelerates the protease inhibition of a bacterial serpin chloropin
    Front Mol Biosci (2023) 10, 1157186-1157186. PubMed  Europe PubMed DOI  PMC  EPMC
  16. 2021
  17. Eszterbauer,E., Szego,D., Ursu,K., Sipos,D. and Gellert,A.
    Serine protease inhibitors of the whirling disease parasite Myxobolus cerebralis (Cnidaria, Myxozoa): Expression profiling and functional predictions
    PLoS ONE (2021) 16, e0249266-e0249266. PubMed  Europe PubMed DOI  PMC  EPMC
  18. Xu,N., Bai,X., Liu,Y., Yang,Y., Tang,B., Shi,H.N., Vallee,I., Boireau,P., Liu,X. and Liu,M.
    The Anti-Inflammatory Immune Response in Early Trichinella spiralis Intestinal Infection Depends on Serine Protease Inhibitor-Mediated Alternative Activation of Macrophages
    J Immunol (2021) 206, 963-977. PubMed  Europe PubMed DOI  PMC  EPMC
  19. 2020
  20. De Marco Verissimo,C., Jewhurst,H.L., Tikhonova,I.G., Urbanus,R.T., Maule,A.G., Dalton,J.P. and Cwiklinski,K.
    Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases
    PLoS Negl Trop Dis (2020) 14, e0008510-e0008510. PubMed  Europe PubMed DOI
  21. Du,W., Gao,Z., Wang,K., Zhao,Y., Zheng,P., Yu,Z., Liu,J. and Yang,X.
    Expression and function assessment of two serpin-type serine protease inhibitors from Haemaphysalis doenitzi
    Res Vet Sci (2020) 132, 1-9. PubMed  Europe PubMed DOI
  22. Gu,X., Chen,Y., Zhang,C., Xie,Y., Shen,N., Wang,C., Zhou,X., Yang,G., He,R., Peng,X., Yang,D., He,Z. and Zhong,Z.
    Molecular characterization and serodiagnostic potential of two serpin proteins in Psoroptes ovis var. cuniculi
    Parasit Vectors (2020) 13, 620-620. PubMed  Europe PubMed DOI  PMC  EPMC
  23. Kim,T.K., Tirloni,L., Berger,M., Diedrich,J.K., Yates JR 3rd, Termignoni,C., Da Silva Vaz I Jr and Mulenga,A.
    Amblyomma americanum serpin 41 (AAS41) inhibits inflammation by targeting chymase and chymotrypsin
    Int J Biol Macromol (2020) 156, 1007-1021. PubMed  Europe PubMed DOI
  24. Pongprayoon,P., Niramitranon,J., Kaewhom,P., Kaewmongkol,S., Suwan,E., Stich,R.W. and Jittapalapong,S.
    Dynamic and structural insights into tick serpin from Ixodes ricinus
    J Biomol Struct Dyn (2020) 38, 2296-2303. PubMed  Europe PubMed DOI
  25. Sanchez Di Maggio,L., Tirloni,L., Uhl,M., Carmona,C., Logullo,C., Mulenga,A., da Silva,V.I., Jr. and Berasain,P.
    Serpins in Fasciola hepatica: insights into host-parasite interactions
    Int J Parasitol (2020) PubMed  Europe PubMed DOI
  26. Taboada,C., Brunetti,A.E., Lyra,M.L., Fitak,R.R., Faigon Soverna,A., Ron,S.R., Lagorio,M.G., Haddad,C.F.B., Lopes,N.P., Johnsen,S., Faivovich,J., Chemes,L.B. and Bari,S.E.
    Multiple origins of green coloration in frogs mediated by a novel biliverdin-binding serpin
    Proc Natl Acad Sci U S A (2020) 117, 18574-18581. PubMed  Europe PubMed DOI
  27. Tolstyko,E.A., Lezzhov,A.A., Pankratenko,A.V., Serebryakova,M.V., Solovyev,A.G. and Morozov,S.Y.
    Detection and in vitro studies of Cucurbita maxima phloem serpin-1 RNA-binding properties
    Biochimie (2020) 170, 118-127. PubMed  Europe PubMed DOI
  28. Wang,F., Song,Z., Chen,J., Wu,Q., Zhou,X., Ni,X. and Dai,J.
    The immunosuppressive functions of two novel tick serpins, HlSerpin-a and HlSerpin-b, from Haemaphysalis longicornis
    Immunology (2020) 159, 109-120. PubMed  Europe PubMed DOI
  29. Wang,Y., Yang,F., Cao,X., Huang,R., Paskewitz,S., Hartson,S.D., Kanost,M.R. and Jiang,H.
    Inhibition of immune pathway-initiating hemolymph protease-14 by Manduca sexta serpin-12, a conserved mechanism for the regulation of melanization and Toll activation in insects
    Insect Biochem Mol Biol (2020) 116, 103261-103261. PubMed  Europe PubMed DOI
  30. Xu,Z., Yan,Y., Zhang,H., Cao,J., Zhou,Y., Xu,Q. and Zhou,J.
    A serpin from the tick Rhipicephalus haemaphysaloides: involvement in vitellogenesis
    Vet Parasitol (2020) 279, 109064-109064. PubMed  Europe PubMed DOI
  31. Yi,N., Yu,P., Wu,L., Liu,Z., Guan,J., Liu,C., Liu,M. and Lu,Y.
    RNAi-mediated silencing of Trichinella spiralis serpin-type serine protease inhibitors results in a reduction in larval infectivity
    Vet Res (2020) 51, 139-139. PubMed  Europe PubMed DOI  PMC  EPMC
  32. 2019
  33. Sang,M., Xu,C., Wei,Z., Wu,X., Guo,Y., Li,J., Wang,Z. and Zhang,J.
    Cloning and high-level SUMO-mediated fusion expression of a serine protease inhibitor from Hyphantria cunea Drury that exhibits activity against papain
    Protein Expr Purif (2019) 158, 36-43. PubMed  Europe PubMed DOI
  34. Tinyou,A., Chaimon,S., Phuphisut,O., Kobpornchai,P., Malaithong,P., Poodeepiyasawat,A., Ieamsuwan,I., Ruangsittichai,J., Pumirat,P., Dekumyoy,P., Reamtong,O. and Adisakwattana,P.
    Molecular cloning and characterization of serine protease inhibitor from food-borne nematode, Gnathostoma spinigerum
    Acta Trop (2019) , 105288-105288. PubMed  Europe PubMed DOI
  35. Tirloni,L., Kim,T.K., Berger,M., Termignoni,C., Da Silva Vaz I Jr and Mulenga,A.
    Amblyomma americanum serpin 27 (AAS27) is a tick salivary anti-inflammatory protein secreted into the host during feeding
    PLoS Negl Trop Dis (2019) 13, e0007660-e0007660. PubMed  Europe PubMed DOI
  36. Toufeeq,S., Wang,J., Zhang,S.Z., Li,B., Hu,P., Zhu,L.B., You,L.L. and Xu,J.P.
    Bmserpin2 is involved in BmNPV infection by suppressing melanization in Bombyx mori
    Insects (2019) 10 PubMed  Europe PubMed DOI
  37. Wang,L., Liu,H., Fu,H., Zhang,L., Guo,P., Xia,Q. and Zhao,P.
    Silkworm serpin32 functions as a negative-regulator in prophenoloxidase activation
    Dev Comp Immunol (2019) 91, 123-131. PubMed  Europe PubMed DOI
  38. Xu,J., Yu,P., Wu,L., Liu,M. and Lu,Y.
    Regulatory effect of two Trichinella spiralis serine protease inhibitors on the host's immune system
    Sci Rep (2019) 9, 17045-17045. PubMed  Europe PubMed DOI  PMC  EPMC
  39. 2018
  40. Chotwiwatthanakun,C., Santimanawong,W., Sobhon,P., Wongtripop,S. and Vanichviriyakit,R.
    Inhibitory effect of a reproductive-related serpin on sperm trypsin-like activity implicates its role in sperm maturation of Penaeus monodon
    Mol Reprod Dev (2018) 85, 205-214. PubMed  Europe PubMed DOI
  41. Gao,Q., Yang,L., Dai,J., Yuan,G., Wang,L., Qian,C., Zhu,B., Liu,C. and Wei,G.
    Characterization and functional analysis of serpin-28 gene from silkworm, Bombyx mori
    J Invertebr Pathol (2018) 159, 18-27. PubMed  Europe PubMed DOI
  42. Kostin,N.N., Bobik,T.V., Shurdova,E.M., Ziganshin,R.H., Surina,E.A., Shagin,D.A., Shagina,I.A., Knorre,V.D., Isaev,V.A., Rudenskaya,G.N., Gabibov,A.G. and Smirnov,I.V.
    Cloning and characterization of serpin from red king crab Paralithodes camtschaticus
    Fish Shellfish Immunol (2018) 81, 99-107. PubMed  Europe PubMed DOI
  43. Roudnicky,P., Vorel,J., Ilgova,J., Benovics,M., Norek,A., Jedlickova,L., Mikes,L., Potesil,D., Zdrahal,Z., Dvorak,J., Gelnar,M. and Kasny,M.
    Identification and partial characterization of a novel serpin from Eudiplozoon nipponicum (Monogenea, Polyopisthocotylea)
    Parasite (2018) 25, 61-61. PubMed  Europe PubMed DOI
  44. Rustgi,S., Boex-Fontvieille,E., Reinbothe,C., Von Wettstein,D. and Reinbothe,S.
    The complex world of plant protease inhibitors: insights into a Kunitz-type cysteine protease inhibitor of Arabidopsis thaliana
    Commun Integr Biol (2018) 11, e1368599-e1368599. PubMed  Europe PubMed DOI  PMC  EPMC
  45. Song,Y.Y., Zhang,Y., Yang,D., Ren,H.N., Sun,G.G., Jiang,P., Liu,R.D., Zhang,X., Cui,J. and Wang,Z.Q.
    The immune protection induced by a serine protease inhibitor from the foodborne parasite Trichinella spiralis
    Front Microbiol (2018) 9, 1544-1544. PubMed  Europe PubMed DOI  PMC  EPMC
  46. Yang,F., Wang,Y., Sumathipala,N., Cao,X., Kanost,M.R. and Jiang,H.
    Manduca sexta serpin-12 controls the prophenoloxidase activation system in larval hemolymph
    Insect Biochem Mol Biol (2018) 99, 27-36. PubMed  Europe PubMed DOI
  47. Yang,L., Irving,J.A., Dai,W., Aguilar,M.I. and Bottomley,S.P.
    Probing the folding pathway of a consensus serpin using single tryptophan mutants
    Sci Rep (2018) 8, 2121-2121. PubMed  Europe PubMed DOI  PMC  EPMC
  48. Yuan,M., Ning,M., Wei,P., Hao,W., Jing,Y., Gu,W., Wang,W. and Meng,Q.
    The function of serpin-2 from Eriocheir sinensis in Spiroplasma eriocheiris infection
    Fish Shellfish Immunol (2018) 76, 21-26. PubMed  Europe PubMed DOI
  49. 2017
  50. Bhattacharjee,L., Singh,D., Gautam,J.K. and Nandi,A.K.
    Arabidopsis thaliana serpins AtSRP4 and AtSRP5 negatively regulate stress-induced cell death and effector-triggered immunity induced by bacterial effector AvrRpt2
    Physiol Plant (2017) 159, 329-339. PubMed  Europe PubMed DOI
  51. Calvo-Iglesias,J., Perez-Estevez,D. and Gonzalez-Fernandez,A.
    MSP22.8 is a protease inhibitor-like protein involved in shell mineralization in the edible mussel Mytilus galloprovincialis
    FEBS Open Bio (2017) 7, 1539-1556. PubMed  Europe PubMed DOI  PMC  EPMC
  52. He,Y., Wang,Y., Zhao,P., Rayaprolu,S., Wang,X., Cao,X. and Jiang,H.
    Serpin-9 and -13 regulate hemolymph proteases during immune responses of Manduca sexta
    Insect Biochem Mol Biol (2017) 90, 71-81. PubMed  Europe PubMed DOI
  53. Kausar,S., Abbas,M.N., Qian,C., Zhu,B., Sun,Y., Sun,Y., Wang,L., Wei,G., Maqsood,I. and Liu,C.L.
    Serpin-14 negatively regulates prophenoloxidase activation and expression of antimicrobial peptides in Chinese oak silkworm Antheraea pernyi
    Dev Comp Immunol (2017) 76, 45-55. PubMed  Europe PubMed DOI
  54. Kausar,S., Abbas,M.N., Qian,C., Zhu,B., Gao,J., Sun,Y., Wang,L., Wei,G. and Liu,C.
    Role of Antheraea pernyi serpin 12 in prophenoloxidase activation and immune responses
    Arch Insect Biochem Physiol (2017) 97 PubMed  Europe PubMed DOI
  55. Lin,H., Lin,X., Zhu,J., Yu,X.Q., Xia,X., Yao,F., Yang,G. and You,M.
    Characterization and expression profiling of serine protease inhibitors in the diamondback moth, Plutella xylostella (Lepidoptera: Plutellidae)
    BMC Genomics (2017) 18, 162-162. PubMed  Europe PubMed DOI
  56. Liu,Y., Sun,Y., Wang,Q., Hou,F. and Liu,X.
    Identification and functional characterizations of serpin8, a potential prophenoloxidase-activating protease inhibitor in Pacific white shrimp, Litopenaeus vannamei
    Fish Shellfish Immunol (2017) 60, 492-501. PubMed  Europe PubMed DOI
  57. Polderdijk,S.G.I., Baglin,T.P. and Huntington,J.A.
    Targeting activated protein C to treat hemophilia
    Curr Opin Hematol (2017) 24, 446-452. PubMed  Europe PubMed DOI
  58. Xu,N., Liu,X., Tang,B., Wang,L., Shi,H.N., Boireau,P., Liu,M. and Bai,X.
    Recombinant Trichinella pseudospiralis serine protease inhibitors alter macrophage polarization in vitro
    Front Microbiol (2017) 8, 1834-1834. PubMed  Europe PubMed DOI  PMC  EPMC
  59. Yan,Z., Fang,Q., Liu,Y., Xiao,S., Yang,L., Wang,F., An,C., Werren,J.H. and Ye,G.
    A venom serpin splicing isoform of the endoparasitoid wasp, Pteromalus puparum, suppresses host prophenoloxidase cascade by forming complexes with host hemolymph proteinases
    J Biol Chem (2017) 292, 1038-1051. PubMed  Europe PubMed DOI
  60. 2016
  61. Alves,F.L., Sallai,R.C., Salu,B.R., Miranda,A. and Oliva,M.L.
    Identification and characterisation of serine protease inhibitors from Araucaria angustifolia seeds
    Nat Prod Res (2016) , 1-4. PubMed  Europe PubMed DOI
  62. Johnson,E.T., Skory,C.D., Naumann,T.A., Jairajpuri,M.A. and Dowd,P.F.
    Three sorghum serpin recombinant proteins inhibit midgut trypsin activity and growth of corn earworm
    Agri Gene (2016) 2, 11-16. DOI
  63. Li,Q., Liu,L., Wang,Y., Xie,J., He,L. and Wang,Q.
    Characterization and expression analysis of serpins in the Chinese mitten crab Eriocheir sinensis
    Gene (2016) 575, 632-640. PubMed  Europe PubMed DOI
  64. Liu,Y., Liu,T., Hou,F., Wang,X. and Liu,X.
    Lvserpin3 is involved in shrimp innate immunity via the inhibition of bacterial proteases and proteases involved in prophenoloxidase system
    Fish Shellfish Immunol (2016) 48, 128-135. PubMed  Europe PubMed DOI
  65. Meekins,D.A., Zhang,X., Battaile,K.P., Lovell,S. and Michel,K.
    1.45 A resolution structure of SRPN18 from the malaria vector Anopheles gambiae
    Acta Crystallogr F Struct Biol Commun (2016) 72, 853-862. PubMed  Europe PubMed DOI  PMC  EPMC  S
  66. Mkaouar,H., Akermi,N., Mariaule,V., Boudebbouze,S., Gaci,N., Szukala,F., Pons,N., Marquez,J., Gargouri,A., Maguin,E. and Rhimi,M.
    Siropins, novel serine protease inhibitors from gut microbiota acting on human proteases involved in inflammatory bowel diseases
    Microb Cell Fact (2016) 15, 201-201. PubMed  Europe PubMed DOI  PMC  EPMC
  67. Oliveira,J.P., Salazar,N., Zani,M.B., de Souza,L.R., Passos,S.G., Sant'Ana,A.M., de Andrade,R.A., Marcili,A., Speranca,M.A. and Puzer,L.
    Vioserpin, a serine protease inhibitor from Gloeobacter violaceus possibly regulated by heparin
    Biochimie (2016) 127, 115-120. PubMed  Europe PubMed DOI
  68. Pakchotanon,P., Molee,P., Nuamtanong,S., Limpanont,Y., Chusongsang,P., Limsomboon,J., Chusongsang,Y., Maneewatchararangsri,S., Chaisri,U. and Adisakwattana,P.
    Molecular characterization of serine protease inhibitor isoform 3, SmSPI, from Schistosoma mansoni
    Parasitol Res (2016) 115, 2981-2994. PubMed  Europe PubMed DOI
  69. Tirloni,L., Kim,T.K., Coutinho,M.L., Ali,A., Seixas,A., Termignoni,C., Mulenga,A. and da Silva Vaz,I.
    The putative role of Rhipicephalus microplus salivary serpins in the tick-host relationship
    Insect Biochem Mol Biol (2016) 71, 12-28. PubMed  Europe PubMed DOI
  70. Xu,T., Lew-Tabor,A. and Rodriguez-Valle,M.
    Effective inhibition of thrombin by Rhipicephalus microplus serpin-15 (RmS-15) obtained in the yeast Pichia pastoris
    Ticks Tick Borne Dis (2016) 7, 180-187. PubMed  Europe PubMed DOI
  71. 2015
  72. Ardisson-Araujo,D.M., Rohrmann,G.F., Ribeiro,B.M. and Clem,R.J.
    Functional characterization of Hesp018, a baculovirus-encoded serpin gene
    J Gen Virol (2015) 96, 1150-1160. PubMed  Europe PubMed DOI
  73. Bathige,S.D., Umasuthan,N., Godahewa,G.I., Whang,I., Kim,C., Park,H.C. and Lee,J.
    Three novel clade B serine protease inhibitors from disk abalone, Haliotis discus discus: molecular perspectives and responses to immune challenges and tissue injury
    Fish Shellfish Immunol (2015) 45, 334-341. PubMed  Europe PubMed DOI
  74. Guo,P.C., Dong,Z., Xiao,L., Li,T., Zhang,Y., He,H., Xia,Q. and Zhao,P.
    Silk gland-specific proteinase inhibitor serpin16 from the Bombyx mori shows cysteine proteinase inhibitory activity
    Biochem Biophys Res Commun (2015) 457, 31-36. PubMed  Europe PubMed DOI
  75. Guo,P.C., Dong,Z., Zhao,P., Zhang,Y., He,H., Tan,X., Zhang,W. and Xia,Q.
    Structural insights into the unique inhibitory mechanism of the silkworm protease inhibitor serpin18
    Sci Rep (2015) 5, 11863-11863. PubMed  Europe PubMed DOI  PMC  EPMC  S
  76. Liu,D., Wang,L., Yang,L., Qian,C., Wei,G., Dai,L., Li,J., Zhu,B. and Liu,C.
    Serpin-15 from Bombyx mori inhibits prophenoloxidase activation and expression of antimicrobial peptides
    Dev Comp Immunol (2015) 51, 22-28. PubMed  Europe PubMed DOI
  77. Liu,Y., Hou,F., Wang,X. and Liu,X.
    Recombinant expression and characterization of a serine protease inhibitor (Lvserpin7) from the Pacific white shrimp, Litopenaeus vannamei
    Fish Shellfish Immunol (2015) 42, 256-263. PubMed  Europe PubMed DOI
  78. Porter,L., Radulovic,Z., Kim,T., Braz,G.R., da Silva Vaz,I., Jr. and Mulenga,A.
    Bioinformatic analyses of male and female Amblyomma americanum tick expressed serine protease inhibitors (serpins)
    Ticks Tick Borne Dis (2015) 6, 16-30. PubMed  Europe PubMed DOI
  79. Rodriguez Valle,M., Xu,T., Kurscheid,S. and Lew-Tabor,A.E.
    Rhipicephalus microplus serine protease inhibitor family: annotation, expression and functional characterisation assessment
    Parasit Vectors (2015) 8, 7-7. PubMed  Europe PubMed DOI
  80. Valdivieso,E., Perteguer,M.J., Hurtado,C., Campioli,P., Rodriguez,E., Saborido,A., Martinez-Sernandez,V., Gomez-Puertas,P., Ubeira,F.M. and Garate,T.
    ANISERP: a new serpin from the parasite Anisakis simplex
    Parasit Vectors (2015) 8, 399-399. PubMed  Europe PubMed DOI  PMC  EPMC
  81. Wei,X., Xu,J., Yang,J., Liu,X., Zhang,R., Wang,W. and Yang,J.
    Involvement of a serpin serine protease inhibitor (OoSerpin) from mollusc Octopus ocellatus in antibacterial response
    Fish Shellfish Immunol (2015) 42, 79-87. PubMed  Europe PubMed DOI
  82. 2014
  83. Ellisdon,A.M., Zhang,Q., Henstridge,M.A., Johnson,T.K., Warr,C.G., Law,R.H. and Whisstock,J.C.
    High resolution structure of cleaved serpin 42 Da from Drosophila melanogaster
    BMC Struct Biol (2014) 14, 14-14. PubMed  Europe PubMed DOI  PMC  EPMC  S
  84. Ibelli,A.M., Kim,T.K., Hill,C.C., Lewis,L.A., Bakshi,M., Miller,S., Porter,L. and Mulenga,A.
    A blood meal-induced Ixodes scapularis tick saliva serpin inhibits trypsin and thrombin, and interferes with platelet aggregation and blood clotting
    Int J Parasitol (2014) 44, 369-379. PubMed  Europe PubMed DOI
  85. Liu,Y., Hou,F., He,S., Qian,Z., Wang,X., Mao,A., Sun,C. and Liu,X.
    Identification, characterization and functional analysis of a serine protease inhibitor (Lvserpin) from the Pacific white shrimp, Litopenaeus vannamei
    Dev Comp Immunol (2014) 43, 35-46. PubMed  Europe PubMed DOI
  86. Liu,Y., Shi,G., Cui,Z., Luo,D., Song,C., Li,X., Hui,M. and Li,Y.
    PtSerpin from the swimming crab Portunus trituberculatus, a putative regulator of prophenoloxidase activation with antibacterial activity
    Fish Shellfish Immunol (2014) 39, 365-371. PubMed  Europe PubMed DOI
  87. Molehin,A.J., Gobert,G.N., Driguez,P. and McManus,D.P.
    Functional characterization of SjB10, an intracellular serpin from Schistosoma japonicum
    Parasitology (2014) 141, 1746-1760. PubMed  Europe PubMed DOI
  88. Molehin,A.J., Gobert,G.N., Driguez,P. and McManus,D.P.
    Characterisation of a secretory serine protease inhibitor (SjB6) from Schistosoma japonicum
    Parasit Vectors (2014) 7, 330-330. PubMed  Europe PubMed DOI
  89. Moreira,C.J., Waniek,P.J., Valente,R.H., Carvalho,P.C., Perales,J., Feder,D., Geraldo,R.B., Castro,H.C., Azambuja,P., Ratcliffe,N.A. and Mello,C.B.
    Isolation and molecular characterization of a major hemolymph serpin from the triatomine, Panstrongylus megistus
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  90. Swe,P.M. and Fischer,K.
    A scabies mite serpin interferes with complement-mediated neutrophil functions and promotes staphylococcal growth
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  91. Tirloni,L., Seixas,A., Mulenga,A., da Silva Vaz,I., Jr. and Termignoni,C.
    A family of serine protease inhibitors (serpins) in the cattle tick Rhipicephalus (Boophilus) microplus
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  92. Wang,Y.-F., Bai,X., Liu,X.-L., Wang,N., Ding,J. and Liu,M.-Y.
    Prokaryotic expression and purification of Trichinella pseudospiralis serine proteinase inhibitor
    Chin J Biol (2014) 27, 1002-1005.  E
  93. Yang,Y., Hu,D., Wang,L., Liang,C., Hu,X., Xu,J., Huang,Y. and Yu,X.
    Comparison of two serpins of Clonorchis sinensis by bioinformatics, expression, and localization in metacercaria
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  94. Zhao,Y.R., Xu,Y.H., Jiang,H.S., Xu,S., Zhao,X.F. and Wang,J.X.
    Antibacterial activity of serine protease inhibitor 1 from kuruma shrimp Marsupenaeus japonicus
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  95. 2013
  96. Cuiv,O., Gupta,R., Goswami,H.P. and Morrison,M.
    Extending the cellulosome paradigm: The modular Clostridium thermocellum cellulosomal serpin PinA is a broad-spectrum inhibitor of subtilisin-like proteases
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  97. Lei,H., Tian,Y., Chen,W., Wang,X., Li,X., Mao,Q., Sun,J., Li,R., Xu,Y., Liang,C., Huang,Y. and Yu,X.
    The biochemical and immunological characterization of two serpins from Clonorchis sinensis
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  98. Rohrmann,G.F., Erlandson,M.A. and Theilmann,D.A.
    The genome of a baculovirus isolated from Hemileuca sp. encodes a serpin ortholog
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  99. Suwanchaichinda,C., Ochieng,R., Zhuang,S. and Kanost,M.R.
    Manduca sexta serpin-7, a putative regulator of hemolymph prophenoloxidase activation
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  100. Toubarro,D., Avila,M.M., Hao,Y., Balasubramanian,N., Jing,Y., Montiel,R., Faria,T.Q., Brito,R.M. and Simoes,N.
    A serpin released by an entomopathogen impairs clot formation in insect defense system
    PLoS ONE (2013) 8, e69161-e69161. PubMed  Europe PubMed DOI  PMC  EPMC
  101. Wang,L., Ma,Z., Yang,J., Gai,Y., Zhou,Z., Wang,L., Yue,F. and Song,L.
    Identification and characterization of a serine protease inhibitor esserpin from the Chinese mitten crab Eriocheir sinensis
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  102. Wetsaphan,N., Rimphanitchayakit,V., Tassanakajon,A. and Somboonwiwat,K.
    PmSERPIN3 from black tiger shrimp Penaeus monodon is capable of controlling the proPO system
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  103. 2012
  104. Francis,S.E., Ersoy,R.A., Ahn,J.W., Atwell,B.J. and Roberts,T.H.
    Serpins in rice: protein sequence analysis, phylogeny and gene expression during development
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  105. Granzin,J., Huang,Y., Topbas,C., Huang,W., Wu,Z., Misra,S., Hazen,S.L., Blanton,R.E., Lee,X. and Weiergraber,O.H.
    Three-dimensional structure of a schistosome serpin revealing an unusual configuration of the helical subdomain
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  106. Mika,A., Reynolds,S.L., Mohlin,F.C., Willis,C., Swe,P.M., Pickering,D.A., Halilovic,V., Wijeyewickrema,L.C., Pike,R.N., Blom,A.M., Kemp,D.J. and Fischer,K.
    Novel scabies mite serpins inhibit the three pathways of the human complement system
    PLoS ONE (2012) 7, e40489-e40489. PubMed  Europe PubMed DOI  PMC  EPMC
  107. Quezada,L.A., Sajid,M., Lim,K.C. and McKerrow,J.H.
    A blood fluke serine protease inhibitor regulates an endogenous larval elastase
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  108. Rodriguez-Valle,M., Vance,M., Moolhuijzen,P.M., Tao,X. and Lew-Tabor,A.E.
    Differential recognition by tick-resistant cattle of the recombinantly expressed Rhipicephalus microplus serine protease inhibitor-3 (RMS-3)
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  109. Wang,S., Cui,Z., Liu,Y., Li,Q. and Song,C.
    Identification and characterization of a serine protease inhibitor (PtSerpin) in the swimming crab Portunus trituberculatus
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  110. Zhao,Y., Sun,W., Zhang,P., Chi,H., Zhang,M.J., Song,C.Q., Ma,X., Shang,Y., Wang,B., Hu,Y., Hao,Z., Huhmer,A.F., Meng,F., L'Hernault,S.W., He,S.M., Dong,M.Q. and Miao,L.
    Nematode sperm maturation triggered by protease involves sperm-secreted serine protease inhibitor (serpin)
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  111. 2011
  112. Chalaire,K.C., Kim,T.K., Garcia-Rodriguez,H. and Mulenga,A.
    Amblyomma americanum (L.) (Acari: Ixodidae) tick salivary gland serine protease inhibitor (serpin) 6 is secreted into tick saliva during tick feeding
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  113. Jiang,R., Zhang,B., Kurokawa,K., So,Y.I., Kim,E.H., Hwang,H.O., Lee,J.H., Shiratsuchi,A., Zhang,J., Nakanishi,Y., Lee,H.S. and Lee,B.L.
    93-kDa Twin-domain serine protease inhibitor (serpin) has a regulatory function on the beetle toll proteolytic signaling cascade
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  114. Quezada,L.A. and McKerrow,J.H.
    Schistosome serine protease inhibitors: parasite defense or homeostasis?
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  115. 2010
  116. Homvises,T., Tassanakajon,A. and Somboonwiwat,K.
    Penaeus monodon SERPIN, PmSERPIN6, is implicated in the shrimp innate immunity
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  117. Kovarova,Z., Chmelar,J., Sanda,M., Brynda,J., Mares,M. and Rezacova,P.
    Crystallization and diffraction analysis of the serpin IRS-2 from the hard tick Ixodes ricinus
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  118. Wei,W., Wu,H., Xu,H., Zhang,X., Chu,T., Wu,C., Chang,K. and Zhang,Y.
    Cloning and molecular characterization of lycC1INH genes in large yellow croaker (Pseudosciaena crocea)
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  119. Yi,D., Xu,L., Yan,R. and Li,X.
    Haemonchus contortus: cloning and characterization of serpin
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  120. 2009
  121. Jiang,R., Kim,E.H., Gong,J.H., Kwon,H.M., Kim,C.H., Ryu,K.H., Park,J.W., Kurokawa,K., Zhang,J., Gubb,D. and Lee,B.L.
    Three pairs of protease-serpin complexes cooperatively regulate the insect innate immune responses
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  122. Liu,Y., Li,F., Wang,B., Dong,B., Zhang,X. and Xiang,J.
    A serpin from Chinese shrimp Fenneropenaeus chinensis is responsive to bacteria and WSSV challenge
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  123. Tao,M., Pan,G., Hu,H. and Zhou,Z.
    [Identification of a new serpin gene (NbSPN106) from Nosema bombycis]
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  124. 2008
  125. Fetterer,R.H., Miska,K.B., Jenkins,M.C., Barfield,R.C. and Lillehoj,H.
    Identification and characterization of a serpin from Eimeria acervulina
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  126. Han,Y., Yu,H., Yang,X., Rees,H.H., Liu,J. and Lai,R.
    A serine proteinase inhibitor from frog eggs with bacteriostatic activity
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  127. Steenbakkers,P.J., Irving,J.A., Harhangi,H.R., Swinkels,W.J., Akhmanova,A., Dijkerman,R., Jetten,M.S., van der Drift,C., Whisstock,J.C. and Op den Camp,H.J.
    A serpin in the cellulosome of the anaerobic fungus Piromyces sp. strain E2
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  128. Zhang,Q., Law,R.H., Bottomley,S.P., Whisstock,J.C. and Buckle,A.M.
    A structural basis for loop C-sheet polymerization in serpins
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  129. Zhou,Y., Zheng,M., Shi,Q., Zhang,L., Zhen,W., Chen,W. and Zhang,Y.
    An epididymis-specific secretory protein HongrES1 critically regulates sperm capacitation and male fertility
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  130. 2007
  131. Mulenga,A., Khumthong,R. and Blandon,M.A.
    Molecular and expression analysis of a family of the Amblyomma americanum tick lospins
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    The N terminus of the serpin, tengpin, functions to trap the metastable native state
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  133. 2006
  134. [YEAR:1-1-2006]Luke,C.J., Pak,S.C., Askew,D.J., Askew,Y.S., Smith,J.E. and Silverman,G.A.
    Selective conservation of the rsl-encoding, proteinase inhibitory-type, clade l serpins in Caenorhabditis species
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    Anti-hemostatic effects of a serpin from the saliva of the tick Ixodes ricinus
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  136. 2005
  137. [YEAR:28-9-2005]Bots,M., Kolfschoten,I.G., Bres,S.A., Rademaker,M.T., de Roo,G.M., Kruse,M., Franken,K.L., Hahne,M., Froelich,C.J., Melief,C.J., Offringa,R. and Medema,J.P.
    SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity
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    A serine protease inhibitor (serpin) from Haemaphysalis longicornis as an anti-tick vaccine
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  139. MacLennan,K., McLean,K. and Knox,D.P.
    Serpin expression in the parasitic stages of Trichostrongylus vitrinus, an ovine intestinal nematode
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  140. Nappi,A.J., Frey,F. and Carton,Y.
    Drosophila serpin 27A is a likely target for immune suppression of the blood cell-mediated melanotic encapsulation response
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    Characterization of a novel vaccine candidate and serine proteinase inhibitor from Schistosoma japonicum (Sj serpin)
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  142. 2004
  143. Askew,D.J., Askew,Y.S., Kato,Y., Turner,R.F., Dewar,K., Lehoczky,J. and Silverman,G.A.
    Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus
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    Identification and activity of a lower eukaryotic serine proteinase inhibitor (serpin) from Cyanea capillata: analysis of a jellyfish serpin, jellypin
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  145. Nathaniel,R., MacNeill,A.L., Wang,Y.X., Turner,P.C. and Moyer,R.W.
    Cowpox virus CrmA, myxoma virus SERP2 and baculovirus P35 are not functionally interchangeable caspase inhibitors in poxvirus infections
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    Characterization of novel squamous cell carcinoma antigen-related molecules in mice
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  147. 2002
  148. Irving,J.A., Steenbakkers,P.J., Lesk,A.M., Op den Camp,H.J., Pike,R.N. and Whisstock,J.C.
    Serpins in prokaryotes
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  149. Weaver,M., Leshley,K., Sands,H., Gritman,K.R., Legos,J.J. and Tuma,R.F.
    LEX032, a novel recombinant serpin, protects the brain after transient focal ischemia
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  150. 2000
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    Inhibitory serpins from wheat grain with reactive centers resembling glutamine-rich repeats of prolamin storage proteins. Cloning and characterization of five major molecular forms
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  152. 1996
  153. Rasmussen,S.K., Dahl,S.W., Norgard,A. and Hejgaard,J.
    A recombinant wheat serpin with inhibitory activity
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  154. 1995
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    The primary elastase inhibitor (elastasin) and trypsin inhibitor (contrapsin) in the goat are serpins related to human alpha 1-anti-chymotrypsin
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  156. 1993
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    Isolation and characterization of an intracellular serine proteinase inhibitor from a monkey kidney epithelial cell line
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    Molecular cloning of silkworm (Bombyx mori) antichymotrypsin. A new member of the serpin superfamily of proteins from insects
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  159. 1991
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    Molecular cloning and characterization of rat contrapsin-like protease inhibitor and related proteins
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