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Literature for inhibitor I04.019: heparin cofactor II

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2020
  1. Bano,S., Fatima,S., Ahamad,S., Ansari,S., Gupta,D., Tabish,M., Rehman,S.U. and Jairajpuri,M.A.
    Identification and characterization of a novel isoform of heparin cofactor II in human liver
    IUBMB Life PubMed  Europe PubMed DOI
    2. 2013
  2. Huntington,J.A.
    Thrombin inhibition by the serpins
    J Thromb Haemost11 Suppl 1, 254-264. PubMed  Europe PubMed DOI
  3. Kalle,M., Papareddy,P., Kasetty,G., Tollefsen,D.M., Malmsten,M., Morgelin,M. and Schmidtchen,A.
    Proteolytic activation transforms heparin cofactor II into a host defense molecule
    J Immunol190, 6303-6310. PubMed  Europe PubMed DOI
    4. 2011
  4. Gierczak,R.F., Sutherland,J.S., Bhakta,V., Toltl,L.J., Liaw,P.C. and Sheffield,W.P.
    Retention of thrombin inhibitory activity by recombinant serpins expressed as integral membrane proteins tethered to the surface of mammalian cells
    J Thromb Haemost9, 2424-2435. PubMed  Europe PubMed DOI
    5. 2010
  5. Tollefsen,D.M.
    Vascular dermatan sulfate and heparin cofactor II
    Prog Mol Biol Transl Sci93, 351-372. PubMed  Europe PubMed DOI  K
    6. 2006
  6. [YEAR:30-4-2006]Sutherland,J.S., Bhakta,V. and Sheffield,W.P.
    Investigating serpin-enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II
    Thromb Res117, 447-461. PubMed  Europe PubMed DOI
  7. [YEAR:26-9-2006]Sutherland,J.S., Bhakta,V., Filion,M.L. and Sheffield,W.P.
    The transferable tail: fusion of the N-terminal acidic extension of heparin cofactor II to alpha1-proteinase inhibitor M358R specifically increases the rate of thrombin inhibition
    Biochemistry45, 11444-11452. PubMed  Europe PubMed DOI
    8. 2004
  8. [YEAR:23-11-2004]Filion,M.L., Bhakta,V., Nguyen,L.H., Liaw,P.S. and Sheffield,W.P.
    Full or partial substitution of the reactive center loop of alpha-1-proteinase inhibitor by that of heparin cofactor II: P1 Arg is required for maximal thrombin inhibition
    Biochemistry43, 14864-14872. PubMed  Europe PubMed DOI
  9. [YEAR:2-8-2004]Fortenberry,Y.M., Whinna,H.C., Gentry,H.R., Myles,T., Leung,L.L. and Church,F.C.
    Molecular mapping of the thrombin-heparin cofactor II complex
    J Biol Chem279, 43237-43244. PubMed  Europe PubMed DOI
  10. [YEAR:30-12-2004]Verhamme,I.M., Bock,P.E. and Jackson,C.M.
    The preferred pathway of glycosaminoglycan-accelerated inactivation of thrombin by heparin cofactor II
    J Biol Chem279, 9785-9795. PubMed  Europe PubMed DOI
    11. 2002
  11. [YEAR:20-8-2002]Baglin,T.P., Carrell,R.W., Church,F.C., Esmon,C.T. and Huntington,J.A.
    Crystal structures of native and thrombin-complexed heparin cofactor II reveal a multistep allosteric mechanism
    Proc Natl Acad Sci U S A99, 11079-11084. PubMed  Europe PubMed DOI  S
  12. Bohme,C., Nimtz,M., Grabenhorst,E., Conradt,H.S., Strathmann,A. and Ragg,H.
    Tyrosine sulfation and N-glycosylation of human heparin cofactor II from plasma and recombinant Chinese hamster ovary cells and their effects on heparin binding
    Eur J Biochem269, 977-988. PubMed  Europe PubMed DOI
  13. [YEAR:31-5-2002]Mitchell,J.W. and Church,F.C.
    Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II promote intramolecular interactions during glycosaminoglycan binding and thrombin inhibition
    J Biol Chem277, 19823-19830. PubMed  Europe PubMed DOI
    14. 1998
  14. [YEAR:20-11-1998]Myles,T., Church,F.C., Whinna,H.C., Monard,D. and Stone,S.R.
    Role of thrombin anion-binding exosite-I in the formation of thrombin-serpin complexes
    J Biol Chem273, 31203-31208. PubMed  Europe PubMed DOI
    15. 1994
  15. [YEAR:18-1-1994]Westrup,D. and Ragg,H.
    Secondary thrombin-binding site, glycosaminoglycan binding domain and reactive center region of leuserpin-2 are strongly conserved in mammalian species
    Biochim Biophys Acta1217, 93-96. PubMed  Europe PubMed DOI
    16. 1993
  16. [YEAR:15-2-1993]Sheehan,J.P., Wu,Q., Tollefsen,D.M. and Sadler,J.E.
    Mutagenesis of thrombin selectively modulates inhibition by serpins heparin cofactor II and antithrombin III. Interaction with the anion-binding exosite determines heparin cofactor II specificity
    J Biol Chem268, 3639-3645. PubMed  Europe PubMed
    17. 1990
  17. [YEAR:25-12-1990]Ragg,H., Ulshofer,T. and Gerewitz,J.
    Glycosaminoglycan-mediated leuserpin-2/thrombin interaction. Structure-function relationships
    J Biol Chem265, 22386-22391. PubMed  Europe PubMed
  18. [YEAR:25-3-1990]Ragg,H., Ulshofer,T. and Gerewitz,J.
    On the activation of human leuserpin-2, a thrombin inhibitor, by glycosaminoglycans
    J Biol Chem265, 5211-5218. PubMed  Europe PubMed
    19. 1988
  19. [YEAR:25-8-1988]Ragg,H. and Preibisch,G.
    Structure and expression of the gene coding for the human serpin hLS2
    J Biol Chem263, 12129-12134. PubMed  Europe PubMed
    20. 1986
  20. Bjork,I. and Danielsson,A.
    Antithrombin and related inhibitors of coagulation proteinases
    [ISSN:0-444-80763-2] (1986) 489-514.  V
  21. [YEAR:29-5-1986]Inhorn,R.C. and Tollefsen,D.M.
    Isolation and characterization of a partial cDNA clone for heparin cofactor II1
    Biochem Biophys Res Commun137, 431-436. PubMed  Europe PubMed
  22. [YEAR:24-1-1986]Ragg,H.
    A new member of the plasma protease inhibitor gene family
    Nucleic Acids Res14, 1073-1088. PubMed  Europe PubMed
    23. 1985
  23. Church,F.C., Noyes,C.M. and Griffith,M.J.
    Inhibition of chymotrypsin by heparin cofactor II
    Proc Natl Acad Sci U S A82, 6431-6434. PubMed  Europe PubMed
  24. [YEAR:25-3-1985]Parker,K.A. and Tollefsen,D.M.
    The protease specificity of heparin cofactor II. Inhibition of thrombin generated during coagulation
    J Biol Chem260, 3501-3505. PubMed  Europe PubMed
  25. [YEAR:1-8-1984]Abildgaard,U. and Larsen,M.L.
    Assay of dermatan sulfate cofactor (heparin cofactor II) activity in human plasma
    Thromb Res35, 257-266. PubMed  Europe PubMed
    26. 1983
  26. Griffith,M.J., Carraway,T., White,G.C. and Dombrose,F.A.
    Heparin cofactor activities in a family with hereditary antithrombin III deficiency: evidence for a second heparin cofactor in human plasma
    Blood61, 111-118. PubMed  Europe PubMed
  27. [YEAR:10-6-1983]Tollefsen,D.M., Pestka,C.A. and Monafo,W.J.
    Activation of heparin cofactor II by dermatan sulfate
    J Biol Chem258, 6713-6716. PubMed  Europe PubMed
  28. [YEAR:1-12-1983]Witt,I., Kaiser,C., Schrenk,W.J. and Wunderwald,P.
    Amino acid composition and N-terminal sequence of antithrombin BM
    Thromb Res32, 513-518. PubMed  Europe PubMed
    29. 1982
  29. [YEAR:10-3-1982]Tollefsen,D.M., Majerus,D.W. and Blank,M.K.
    Heparin cofactor II. Purification and properties of a heparin-dependent inhibitor of thrombin in human plasma
    J Biol Chem257, 2162-2169. PubMed  Europe PubMed
  30. [YEAR:1-2-1982]Wunderwald,P., Schrenk,W.J. and Port,H.
    Antithrombin BM from human plasma: an antithrombin binding moderately to heparin
    Thromb Res25, 177-191. PubMed  Europe PubMed
    31. 1974
  31. [YEAR:2-4-1974]Briginshaw,G.F. and Shanberge,J.N.
    Identification of two distinct heparin cofactors in human plasma. Separation and partial purification
    Arch Biochem Biophys161, 683-690. PubMed  Europe PubMed

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