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Literature for inhibitor I04.012: megsin

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature

(Topics flags: M Mutation, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Liu,J., Zhou,B., Chen,Z., Li,S., Liu,Y., Yang,Y. and Mo,R.
    Functional Characterization of a Novel In-Frame Indel and a Founder Variant in SERPINB7 Associated With Palmoplantar Keratoderma
    J Dermatol (2026) PubMed  Europe PubMed DOI
    2. 2021
  2. Cohen-Barak,E., Azzam,W., Koetsier,J.L., Danial-Farran,N., Barcan,M., Hriesh,M., Khayat,M., Edison,N., Krausz,J., Gafni-Amsalem,C., Kubo,A., Godsel,L.M., Ziv,M. and Allon-Shalev,S.
    Acral peeling in Nagashima type palmo-plantar keratosis patients reveals the role of serine protease inhibitor B 7 in keratinocyte adhesion
    Exp Dermatol (2021) PubMed  Europe PubMed DOI
  3. Huang,C., Yang,Y., Huang,X. and Zhou,Z.
    Nagashima-Type Palmoplantar Keratosis: Clinical Characteristics, Genetic Characterization, and Clinical Management
    Biomed Res Int (2021) 2021, 8841994-8841994. PubMed  Europe PubMed DOI  PMC  EPMC  V
    4. 2015
  4. Suzuki,S., Nomura,T., Mizuno,O., Fujita,Y. and Shimizu,H.
    Identification of previously unknown SERPINB7 splice variants in patients with Nagashima-type palmoplantar keratosis reveals the importance of the CD-loop of SERPINB7
    Br J Dermatol (2015) 173, 1288-1290. PubMed  Europe PubMed DOI  M
    5. 2014
  5. Kubo,A.
    Nagashima-type palmoplantar keratosis: a common asian type caused by SERPINB7 protease inhibitor deficiency
    J Invest Dermatol (2014) 134, 2076-2079. PubMed  Europe PubMed DOI  M
  6. Mizuno,O., Nomura,T., Suzuki,S., Takeda,M., Ohguchi,Y., Fujita,Y., Nishie,W., Sugiura,K., Akiyama,M. and Shimizu,H.
    Highly prevalent SERPINB7 founder mutation causes pseudodominant inheritance pattern in Nagashima-type palmoplantar keratosis
    Br J Dermatol (2014) 171, 847-853. PubMed  Europe PubMed DOI  M
    7. 2013
  7. Kubo,A., Shiohama,A., Sasaki,T., Nakabayashi,K., Kawasaki,H., Atsugi,T., Sato,S., Shimizu,A., Mikami,S., Tanizaki,H., Uchiyama,M., Maeda,T., Ito,T., Sakabe,J., Heike,T., Okuyama,T., Kosaki,R., Kosaki,K., Kudoh,J., Hata,K., Umezawa,A., Tokura,Y., Ishiko,A., Niizeki,H., Kabashima,K., Mitsuhashi,Y. and Amagai,M.
    Mutations in SERPINB7, encoding a member of the serine protease inhibitor superfamily, cause Nagashima-type palmoplantar keratosis
    Am J Hum Genet (2013) 93, 945-956. PubMed  Europe PubMed DOI  PMC  EPMC  M
    8. 2007
  8. Inagi,R., Izuhara,Y., Tominaga,N., Nangaku,M., Kurokawa,K. and Miyata,T.
    Establishment of a sandwich ELISA for human megsin, a kidney-specific serine protease inhibitor
    Nephrol Dial Transplant (2007) 22, 3311-3317. PubMed  Europe PubMed DOI
  9. Miyata,T., Li,M., Yu,X. and Hirayama,N.
    Megsin gene: its genomic analysis, pathobiological functions, and therapeutic perspectives
    Curr Genomics (2007) 8, 203-208. PubMed  Europe PubMed  PMC  EPMC  M
    10. 2005
  10. [YEAR:23-3-2005]Inagi,R., Nangaku,M., Usuda,N., Shimizu,A., Onogi,H., Izuhara,Y., Nakazato,K., Ueda,Y., Oishi,H., Takahashi,S., Yamamoto,M., Suzuki,D., Kurokawa,K., van Ypersele de Strihou,C. and Miyata,T.
    Novel serpinopathy in rat kidney and pancreas induced by overexpression of megsin
    J Am Soc Nephrol (23-3-2005) 16, 1339-1349. PubMed  Europe PubMed DOI
  11. Inagi,R., Nangaku,M. and Miyata,T.
    Synergistic contributions of carbonyl stress and megsin in diabetic nephropathy
    Ann N Y Acad Sci (2005) 1043, 605-608. PubMed  Europe PubMed DOI
  12. Miyata,T., Inagi,R., Sugiyama,S. and Usuda,N.
    Serpinopathy and endoplasmic reticulum stress
    Med Mol Morphol (2005) 38, 73-78. PubMed  Europe PubMed DOI
    13. 2004
  13. Onogi,H., Inagi,R., Nangaku,M., Ueda,Y., Miyata,T. and Kurokawa,K.
    Accelerated glomerular injury in hemi-nephrectomized transgenic mice of mesangial cell-predominant serpin, megsin
    Nephron Exp Nephrol (2004) 96, e127-e133. PubMed  Europe PubMed DOI
    14. 2002
  14. Miyata,T., Inagi,R., Nangaku,M., Imasawa,T., Sato,M., Izuhara,Y., Suzuki,D., Yoshino,A., Onogi,H., Kimura,M., Sugiyama,S. and Kurokawa,K.
    Overexpression of the serpin megsin induces progressive mesangial cell proliferation and expansion
    J Clin Invest (2002) 109, 585-593. PubMed  Europe PubMed DOI  PMC  EPMC
    15. 2001
  15. [YEAR:7-9-2001]Inagi,R., Miyata,T., Suzuki,D., Toyoda,M., Wada,T., Ueda,Y., Izuhara,Y., Sakai,H., Nangaku,M. and Kurokawa,K.
    Specific tissue distribution of megsin, a novel serpin, in the glomerulus and its up-regulation in IgA nephropathy
    Biochem Biophys Res Commun (7-9-2001) 286, 1098-1106. PubMed  Europe PubMed DOI
  16. Nangaku,M., Miyata,T., Suzuki,D., Umezono,T., Hashimoto,T., Wada,T., Yagi,M., Nagano,N., Inagi,R. and Kurokawa,K.
    Cloning of rodent megsin revealed its up-regulation in mesangioproliferative nephritis
    Kidney Int (2001) 60, 641-652. PubMed  Europe PubMed DOI
    17. 2000
  17. Szelestei,T., Bahring,S., Kovacs,T., Vas,T., Salamon,C., Busjahn,A., Luft,F.C. and Nagy,J.
    Association of a uteroglobin polymorphism with rate of progression in patients with IgA nephropathy
    Am J Kidney Dis (2000) 36, 468-473. PubMed  Europe PubMed DOI
    18. 1999
  18. Suzuki,D., Miyata,T., Nangaku,M., Takano,H., Saotome,N., Toyoda,M., Mori,Y., Zhang,S.Y., Inagi,R., Endoh,M., Kurokawa,K. and Sakai,H.
    Expression of megsin mRNA, a novel mesangium-predominant gene, in the renal tissues of various glomerular diseases
    J Am Soc Nephrol (1999) 10, 2606-2613. PubMed  Europe PubMed
    19. 1998
  19. [YEAR:15-8-1998]Miyata,T., Nangaku,M., Suzuki,D., Inagi,R., Uragami,K., Sakai,H., Okubo,K. and Kurokawa,K.
    A mesangium-predominant gene, megsin, is a new serpin upregulated in IgA nephropathy
    J Clin Invest (15-8-1998) 102, 828-836. PubMed  Europe PubMed DOI  PMC  EPMC

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