Literature for inhibitor I04.007: plasminogen activator inhibitor 2

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, M Mutation, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2023
  1. Alfieri,M., Meo,L. and Ragno,P.
    Posttranscriptional Regulation of the Plasminogen Activation System by Non-Coding RNA in Cancer
    Int J Mol Sci24, PubMed  Europe PubMed DOI  V
  2. Xu,L., Wang,P., Li,L., Li,L., Huang,Y., Zhang,Y., Zheng,X., Yi,P., Zhang,M. and Xu,M.
    circPSD3 is a promising inhibitor of uPA system to inhibit vascular invasion and metastasis in hepatocellular carcinoma
    Mol Cancer22, 174-174. PubMed  Europe PubMed DOI
  3. 2022
  4. Liao,C.L., Hu,R.C., Liao,M.S., Chen,Y.J., Chen,Y.P., Hsieh,H.H., Tai,C.H., Chou,T.C., Chu,C.Y., Chen,Y.J., Lo,L.C. and Lin,J.J.
    Unveiling a novel serpinB2-tripeptidyl peptidase II signaling axis during senescence
    J Cell Sci135, PubMed  Europe PubMed DOI
  5. 2020
  6. Belfiore,L., Saunders,D.N., Ranson,M. and Vine,K.L.
    N-Alkylisatin-Loaded Liposomes Target the Urokinase Plasminogen Activator System in Breast Cancer
    Pharmaceutics12, PubMed  Europe PubMed DOI
  7. Ranucci,M., Sitzia,C., Baryshnikova,E., Di Dedda,U., Cardani,R., Martelli,F. and Corsi Romanelli,M.
    Covid-19-Associated Coagulopathy: Biomarkers of Thrombin Generation and Fibrinolysis Leading the Outcome
    J Clin Med9, PubMed  Europe PubMed DOI
  8. Westrick,R.J., Rojkjaer,L.P., Yang,A.Y., Roh,M.H., Siebert,A.E. and Ginsburg,D.
    Deficiency of Plasminogen Activator Inhibitor-2 Results in Accelerated Tumor Growth
    J Thromb Haemost18, 2968-2975. PubMed  Europe PubMed DOI
  9. Yang,B., Zhang,D., Qian,J. and Cheng,Y.
    Chelerythrine suppresses proliferation and metastasis of human prostate cancer cells via modulating MMP/TIMP/NF-kappaB system
    Mol Cell Biochem474, 199-208. PubMed  Europe PubMed DOI
  10. 2016
  11. Neilands,J., Bikker,F.J. and Kinnby,B.
    PAI-2/SerpinB2 inhibits proteolytic activity in a P. gingivalis-dominated multispecies bacterial consortium
    Arch Oral Biol70, 1-8. PubMed  Europe PubMed DOI
  12. Wyatt,A.R., Cater,J.H. and Ranson,M.
    PZP and PAI-2: structurally-diverse, functionally similar pregnancy proteins?
    Int J Biochem Cell Biol79, 113-117. PubMed  Europe PubMed DOI
  13. 2015
  14. Vine,K.L., Lobov,S., Indira Chandran,V., Harris,N.L. and Ranson,M.
    Improved pharmacokinetic and biodistribution properties of the selective urokinase inhibitor PAI-2 (serpinB2) by site-specific PEGylation: implications for drug delivery
    Pharm Res32, 1045-1054. PubMed  Europe PubMed DOI  U
  15. 2014
  16. Gardiner,E.E. and Medcalf,R.L.
    Is plasminogen activator inhibitor type 2 really a plasminogen activator inhibitor after all?
    J Thromb Haemost12, 1703-1705. PubMed  Europe PubMed DOI
  17. 2013
  18. Zhao,A., Yang,Z., Sun,R., Grinchuk,V., Netzel-Arnett,S., Anglin,I.E., Driesbaugh,K.H., Notari,L., Bohl,J.A., Madden,K.B., Urban,J.F., Jr., Antalis,T.M. and Shea-Donohue,T.
    SerpinB2 is critical to Th2 immunity against enteric nematode infection
    J Immunol190, 5779-5787. PubMed  Europe PubMed DOI
  19. 2011
  20. Lobov,S. and Ranson,M.
    Molecular competition between plasminogen activator inhibitors type -1 and -2 for urokinase: implications for cellular proteolysis and adhesion in cancer
    Cancer Lett303, 118-127. PubMed  Europe PubMed DOI
  21. Medcalf,R.L.
    Plasminogen activator inhibitor type 2: still an enigmatic serpin but a model for gene regulation
    Methods Enzymol499, 105-134. PubMed  Europe PubMed DOI
  22. 2006
  23. [YEAR:21-8-2006]Darnell,G.A., Schroder,W.A., Gardner,J., Harrich,D., Yu,H., Medcalf,R.L., Warrilow,D., Antalis,T.M., Sonza,S. and Suhrbier,A.
    Serpinb2 is an inducible host factor involved in enhancing HIV-1 transcription and replication
    J Biol Chem281, 31348-31358. PubMed  Europe PubMed DOI
  24. 2005
  25. Darnell,G.A., Antalis,T.M., Rose,B.R. and Suhrbier,A.
    Silencing of integrated human papillomavirus type 18 oncogene transcription in cells expressing serpinB2
    J Virol79, 4246-4256. PubMed  Europe PubMed DOI
  26. [YEAR:22-9-2005]Di Giusto,D.A., Sutherland,A.P., Jankova,L., Harrop,S.J., Curmi,P.M. and King,G.C.
    Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution-implications for serpin mechanistic model and prediction of nsSNP activities
    J Mol Biol353, 1069-1080. PubMed  Europe PubMed DOI
  27. Medcalf,R.L. and Stasinopoulos,S.J.
    The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2
    FEBS J272, 4858-4867. PubMed  Europe PubMed DOI  V
  28. [YEAR:20-9-2005]Shioji,G., Ezura,Y., Nakajima,T., Ohgaki,K., Fujiwara,H., Kubota,Y., Ichikawa,T., Inoue,K., Shuin,T., Habuchi,T., Ogawa,O., Nishimura,T. and Emi,M.
    Nucleotide variations in genes encoding plasminogen activator inhibitor-2 and serine proteinase inhibitor B10 associated with prostate cancer
    J Hum Genet50, 507-515. PubMed  Europe PubMed DOI  M
  29. [YEAR:12-11-2005]Wang,X., Hou,M., Tan,L., Sun,X., Zhang,Y., Li,P. and Zhu,Y.
    A hybrid protein of the amino-terminal fragment of urokinase and mutant plasminogen activator inhibitor-2 efficiently inhibits tumor cell invasion and metastasis
    J Cancer Res Clin Oncol131, 129-136. PubMed  Europe PubMed DOI
  30. 2004
  31. Lian,X. and Yang,T.
    Plasminogen activator inhibitor 2: expression and role in differentiation of epidermal keratinocyte
    Biol Cell96, 109-116. PubMed  Europe PubMed DOI
  32. 2003
  33. [YEAR:27-2-2003]Wilczynska,M., Lobov,S. and Ny,T.
    The spontaneous polymerization of plasminogen activator inhibitor type-2 and Z-antitrypsin are due to different molecular aberrations
    FEBS Lett537, 11-16. PubMed  Europe PubMed DOI  M
  34. [YEAR:15-4-2003]Wilczynska,M., Lobov,S., Ohlsson,P.I. and Ny,T.
    A redox-sensitive loop regulates plasminogen activator inhibitor type 2 (PAI-2) polymerization
    EMBO J22, 1753-1761. PubMed  Europe PubMed DOI
  35. 2001
  36. [YEAR:16-11-2001]Jankova,L., Harrop,S.J., Saunders,D.N., Andrews,J.L., Bertram,K.C., Gould,A.R., Baker,M.S. and Curmi,P.M.
    Crystal structure of the complex of plasminogen activator inhibitor 2 with a peptide mimicking the reactive center loop
    J Biol Chem276, 43374-43382. PubMed  Europe PubMed DOI  S
  37. 1999
  38. Harrop,S.J., Jankova,L., Coles,M., Jardine,D., Whittaker,J.S., Gould,A.R., Meister,A., King,G.C., Mabbutt,B.C. and Curmi,P.M.
    The crystal structure of plasminogen activator inhibitor 2 at 2.0 A resolution: implications for serpin function
    Structure7, 43-54. PubMed  Europe PubMed DOI  S
  39. 1997
  40. [YEAR:4-4-1997]McCarthy,B.J. and Worrall,D.M.
    Analysis of serpin inhibitory function by mutagenesis of ovalbumin and generation of chimeric ovalbumin/PAI-2 fusion proteins
    J Mol Biol267, 561-569. PubMed  Europe PubMed DOI
  41. 1993
  42. Mikus,P., Urano,T., Liljestrom,P. and Ny,T.
    Plasminogen-activator inhibitor type 2 (PAI-2) is a spontaneously polymerising SERPIN. Biochemical characterisation of the recombinant intracellular and extracellular forms
    Eur J Biochem218, 1071-1082. PubMed  Europe PubMed DOI
  43. 1990
  44. Andreasen,P.A., Georg,B., Lund,L.R., Riccio,A. and Stacey,S.N.
    Plasminogen activator inhibitors: hormonally regulated serpins
    Mol Cell Endocrinol68, 1-19. PubMed  Europe PubMed DOI