Literature for inhibitor I04.006: serpin B1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, M Mutation, K Knockout, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Yan,J., Liu,X., Zhu,H., Li,L., Pan,H., Bao,R., Li,Q., Sun,J., Song,H. and Su,M.
    SERPINB1 promotes porcine deltacoronavirus replication by targeting the viral accessory protein NS7a
    Vet Microbiol (2025) 313, 110869-110869. PubMed  Europe PubMed DOI
  2. 2024
  3. Wang,T., Rathee,A., Pemberton,P.A. and Lood,C.
    Exogenous Serpin B1 restricts Immune complex-mediated NET formation via inhibition of a chymotrypsin-like protease and enhances microbial phagocytosis
    J Biol Chem (2024) , 107533-107533. PubMed  Europe PubMed DOI
  4. 2022
  5. Xie,S., Xing,Y., Shi,W., Zhang,M., Chen,M., Fang,W., Liu,S., Zhang,T., Zeng,X., Chen,S., Wang,S., Deng,W. and Tang,Q.
    Cardiac fibroblast heat shock protein 47 aggravates cardiac fibrosis post myocardial ischemia-reperfusion injury by encouraging ubiquitin specific peptidase 10 dependent Smad4 deubiquitination
    Acta Pharm Sin B (2022) 12, 4138-4153. PubMed  Europe PubMed DOI  PMC  EPMC
  6. 2021
  7. Ishida,M., Kawao,N., Mizukami,Y., Takafuji,Y. and Kaji,H.
    Serpinb1a suppresses osteoclast formation
    Biochem Biophys Rep (2021) 26, 101004-101004. PubMed  Europe PubMed DOI  PMC  EPMC
  8. Shibamura-Fujiogi,M., Yuki,K. and Hou,L.
    Cathepsin L regulates pathogenicCD4 T cells in experimental autoimmune encephalomyelitis
    Int Immunopharmacol (2021) 93, 107425-107425. PubMed  Europe PubMed DOI
  9. 2020
  10. Hou,L. and Yuki,K.
    SerpinB1 expression in Th17 cells depends on hypoxia-inducible factor 1-alpha
    Int Immunopharmacol (2020) 87, 106826-106826. PubMed  Europe PubMed DOI
  11. Kassem,D.H., Adel,A., Sayed,G.H. and Kamal,M.M.
    A Novel SERPINB1 Single-Nucleotide Polymorphism Associated With Glycemic Control and beta-Cell Function in Egyptian Type 2 Diabetic Patients
    Front Endocrinol (Lausanne) (2020) 11, 450-450. PubMed  Europe PubMed DOI  PMC  EPMC  M
  12. Pemberton,P.A.
    Expression and purification of recombinant human serpin B1 yields novel molecules with altered protease inhibitory activities: functional implications
    Protein Expr Purif (2020) , 105595-105595. PubMed  Europe PubMed DOI
  13. Stanton,B.A., Hampton,T.H. and Ashare,A.
    SARS-CoV-2 (COVID-19) and Cystic Fibrosis
    Am J Physiol Lung Cell Mol Physiol (2020) 319, L408-L415. PubMed  Europe PubMed DOI
  14. 2019
  15. Burgener,S.S., Leborgne,N.G.F., Snipas,S.J., Salvesen,G.S., Bird,P.I. and Benarafa,C.
    Cathepsin G inhibition by serpinb1 and serpinb6 prevents programmed necrosis in neutrophils and monocytes and reduces GSDMD-driven inflammation
    Cell Rep (2019) 27, 3646-3656. PubMed  Europe PubMed DOI
  16. Yao,W., Han,X., Guan,Y., Guan,J., Wu,S., Chen,C., Li,H. and Hei,Z.
    Neutrophil elastase inhibitors suppress oxidative stress in lung during liver transplantation
    Oxid Med Cell Longev (2019) 2019, 7323986-7323986. PubMed  Europe PubMed DOI  PMC  EPMC  I
  17. 2017
  18. Torriglia,A., Martin,E. and Jaadane,I.
    The hidden side of SERPINB1/leukocyte elastase inhibitor
    Semin Cell Dev Biol (2017) 62, 178-186. PubMed  Europe PubMed DOI
  19. 2016
  20. Burgener,S.S., Baumann,M., Basilico,P., Remold-O'Donnell,E., Touw,I.P. and Benarafa,C.
    Myeloid conditional deletion and transgenic models reveal a threshold for the neutrophil survival factor Serpinb1
    Biol Chem (2016) 397, 897-905. PubMed  Europe PubMed DOI
  21. 2015
  22. Hou,L., Cooley,J., Swanson,R., Ong,P.C., Pike,R.N., Bogyo,M., Olson,S.T. and Remold-O'Donnell,E.
    The protease cathepsin L regulates Th17 cell differentiation
    J Autoimmun (2015) 65, 56-63. PubMed  Europe PubMed DOI
  23. 2014
  24. Jaadane,I., Nagbou,A., Behar-Cohen,F. and Torriglia,A.
    Interaction of leukocyte elastase inhibitor/l-DNase II with BCL-2 and BAX
    Biochim Biophys Acta (2014) 1843, 2807-2815. PubMed  Europe PubMed DOI
  25. 2013
  26. Baumann,M., Pham,C.T. and Benarafa,C.
    SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G
    Blood (2013) 121, 19-19. PubMed  Europe PubMed DOI
  27. Wang,L., Li,Q., Wu,L., Liu,S., Zhang,Y., Yang,X., Zhu,P., Zhang,H., Zhang,K., Lou,J., Liu,P., Tong,L., Sun,F. and Fan,Z.
    Identification of SERPINB1 as a physiological inhibitor of human granzyme H
    J Immunol (2013) 190, 1319-1330. PubMed  Europe PubMed DOI
  28. 2012
  29. Farley,K., Stolley,J.M., Zhao,P.C., Cooley,J. and Remold-O'Donnell,E.
    A serpinB1 regulatory mechanism is essential for restricting neutrophil extracellular trap generation
    J Immunol (2012) 189, 4574-4581. PubMed  Europe PubMed DOI
  30. 2011
  31. Benarafa,C.
    The serpinB1 knockout mouse a model for studying neutrophil protease regulation in homeostasis and inflammation
    Methods Enzymol (2011) 499, 135-148. PubMed  Europe PubMed DOI  K
  32. Benarafa,C., Lecuyer,T.E., Baumann,M., Stolley,J.M., Cremona,T.P. and Remold-O'Donnell,E.
    SerpinB1 protects the mature neutrophil reserve in the bone marrow
    J Leukoc Biol (2011) 90, 21-29. PubMed  Europe PubMed DOI
  33. Cooley,J., Sontag,M.K., Accurso,F.J. and Remold-O'Donnell,E.
    SerpinB1 in cystic fibrosis airway fluids: quantity, molecular form and mechanism of elastase inhibition
    Eur Respir J (2011) 37, 1083-1090. PubMed  Europe PubMed DOI
  34. Gong,D., Farley,K., White,M., Hartshorn,K.L., Benarafa,C. and Remold-O'Donnell,E.
    Critical role of serpinB1 in regulating inflammatory responses in pulmonary influenza infection
    J Infect Dis (2011) 204, 592-600. PubMed  Europe PubMed DOI  PMC  EPMC
  35. Jegot,G., Derache,C., Castella,S., Lahouassa,H., Pitois,E., Jourdan,M.L., Remold-O'Donnell,E., Kellenberger,C., Gauthier,F. and Korkmaz,B.
    A substrate-based approach to convert serpinB1 into a specific inhibitor of proteinase 3, the Wegener's granulomatosis autoantigen
    FASEB J (2011) 25, 3019-3031. PubMed  Europe PubMed DOI
  36. 2010
  37. Subramaniam,R., Dassanayake,R.P., Norimine,J., Brown,W.C., Knowles,D.P. and Srikumaran,S.
    Molecular cloning, characterization and in vitro expression of SERPIN B1 of bighorn sheep (Ovis canadensis) and domestic sheep (Ovis aries), and comparison with that of other species
    Vet Immunol Immunopathol (2010) 137, 327-331. PubMed  Europe PubMed DOI
  38. 2009
  39. Tseng,M.Y., Liu,S.Y., Chen,H.R., Wu,Y.J., Chiu,C.C., Chan,P.T., Chiang,W.F., Liu,Y.C., Lu,C.Y., Jou,Y.S. and Chen,J.Y.
    Serine protease inhibitor (SERPIN) B1 promotes oral cancer cell motility and is over-expressed in invasive oral squamous cell carcinoma
    Oral Oncol (2009) 45, 771-776. PubMed  Europe PubMed DOI
  40. 2008
  41. Padron-Barthe,L., Courta,J., Lepretre,C., Nagbou,A. and Torriglia,A.
    Leukocyte elastase inhibitor, the precursor of L-DNase II, inhibits apoptosis by interfering with caspase-8 activation
    Biochim Biophys Acta (2008) 1783, 1755-1766. PubMed  Europe PubMed DOI
  42. 2007
  43. Benarafa,C., Priebe,G.P. and Remold-O'Donnell,E.
    The neutrophil serine protease inhibitor serpinb1 preserves lung defense functions in Pseudomonas aeruginosa infection
    J Exp Med (2007) 204, 1901-1909. PubMed  Europe PubMed DOI  PMC  EPMC  K
  44. Padron-Barthe,L., Lepretre,C., Martin,E., Counis,M.F. and Torriglia,A.
    Conformational modification of serpins transforms leukocyte elastase inhibitor into an endonuclease involved in apoptosis
    Mol Cell Biol (2007) 27, 4028-4036. PubMed  Europe PubMed DOI  PMC  EPMC
  45. 2002
  46. [YEAR:1-11-2002]Benarafa,C., Cooley,J., Zeng,W., Bird,P.I. and Remold-O'Donnell,E.
    Characterization of four murine homologs of the human ov-serpin monocyte neutrophil elastase inhibitor MNEI (SERPINB1)
    J Biol Chem (1-11-2002) 277, 42028-42033. PubMed  Europe PubMed DOI
  47. 2001
  48. [YEAR:25-12-2001]Cooley,J., Takayama,T.K., Shapiro,S.D., Schechter,N.M. and Remold-O'Donnell,E.
    The serpin MNEI inhibits elastase-like and chymotrypsin-like serine proteases through efficient reactions at two active sites
    Biochemistry (25-12-2001) 40, 15762-15770. PubMed  Europe PubMed DOI
  49. 2000
  50. [YEAR:11-8-2000]Perani,P., Zeggai,S., Torriglia,A. and Courtois,Y.
    Mutations on the hinge region of leukocyte elastase inhibitor determine the loss of inhibitory function
    Biochem Biophys Res Commun (11-8-2000) 274, 841-844. PubMed  Europe PubMed DOI
  51. Zeng,W. and Remold-O'Donnell,E.
    Human monocyte/neutrophil elastase inhibitor (MNEI) is regulated by PU.1/Spi-1, Sp1, and NF-kappaB
    J Cell Biochem (2000) 78, 519-532. PubMed  Europe PubMed DOI
  52. 1998
  53. Sun,J., Stephens,R., Mirza,G., Kanai,H., Ragoussis,J. and Bird,P.I.
    A serpin gene cluster on human chromosome 6p25 contains PI6, PI9 and ELANH2 which have a common structure almost identical to the 18q21 ovalbumin serpin genes
    Cytogenet Cell Genet (1998) 82, 273-277. PubMed  Europe PubMed
  54. 1995
  55. Evans,E., Cooley,J. and Remold-O'Donnell,E.
    Characterization and chromosomal localization of ELANH2, the gene encoding human monocyte/neutrophil elastase inhibitor
    Genomics (1995) 28, 235-240. PubMed  Europe PubMed DOI
  56. 1992
  57. Baumann,U., Bode,W., Huber,R., Travis,J. and Potempa,J.
    Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution
    J Mol Biol (1992) 226, 1207-1218. PubMed  Europe PubMed DOI  S
  58. [YEAR:15-6-1992]Remold-O'Donnell,E., Chin,J. and Alberts,M.
    Sequence and molecular characterization of human monocyte/neutrophil elastase inhibitor
    Proc Natl Acad Sci U S A (15-6-1992) 89, 5635-5639. PubMed  Europe PubMed DOI  PMC  EPMC
  59. 1989
  60. Remold-O'Donnell,E., Nixon,J.C. and Rose,R.M.
    Elastase inhibitor. Characterization of the human elastase inhibitor molecule associated with monocytes, macrophages, and neutrophils
    J Exp Med (1989) 169, 1071-1086. PubMed  Europe PubMed  PMC  EPMC
  61. 1985
  62. Remold-O'Donnell,E.
    A fast-acting elastase inhibitor in human monocytes
    J Exp Med (1985) 162, 2142-2155. PubMed  Europe PubMed  PMC  EPMC