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Literature for family I2 unassigned peptidases

Summary Sequences Sequence features Distribution Structure Literature

(Topics flags: S Structure, T Target, E Expression, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Oyama,H. and Inagaki,H.<br>Discovery and Functional Characterization of Kunitz-Type Toxins from the Tetrodotoxin-Bearing Flatworm Planocera Multitencaculata<br>Mar Biotechnol (NY) (2026) 28, 10-10. PubMed  Europe PubMed DOI
    2. 2025
  2. Jin,C., Zhang,J., Tan,X., Wei,F., Bai,Z. and Luo,W.<br>Glycine-rich Kunitz-type Serine Protease Inhibitor (HcGrKuSPI) Prevents Extracellular Degradation of Matrix Proteins during Shell Formation in Hyriopsis Cumingii<br>Mar Biotechnol (NY) (2025) 27, 160-160. PubMed  Europe PubMed DOI
    3. 2024
  3. Flo Diaz,M., Pellizza,L., Duran,R., Alvarez,B. and Fernandez,C.<br>The monodomain Kunitz protein EgKU-7 from Echinococcus granulosus, the dog tapeworm, is a high-affinity trypsin inhibitor with two interaction sites<br>Biochem J (2024) 481, 717-739. PubMed  Europe PubMed DOI
  4. Zhang,X., Jiang,W., Guo,K., Guo,Z., Duan,J., Jing,X., Xia,Q. and Zhao,P.<br>A mutation in the Bombyx mori BmSPI51 gene results in alterations protein abundance in cocoon and unveils compensatory mechanism of silk gland proteinase inhibitors<br>Int J Biol Macromol (2024) , 137001-137001. PubMed  Europe PubMed DOI
    5. 2023
  5. Xu,W., Rustenhoven,J., Nelson,C.A., Dykstra,T., Ferreiro,A., Papadopoulos,Z., Burnham,C.D., Dantas,G., Fremont,D.H. and Kipnis,J.<br>A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan<br>Neuron (2023) 111, 3244-3254. PubMed  Europe PubMed DOI  PMC  EPMC
    6. 2022
  6. Shen,C., Zhang,M., Liang,H., He,J., Zhang,B. and Liang,B.<br>Gene cloning and functional study of PmKSPI from Pinctada fucata martensii<br>Fish Shellfish Immunol (2022) 131, 1157-1165. PubMed  Europe PubMed DOI
    7. 2021
  7. Sagasti,C., Casaravilla,C., Fernandez,C., Flo,M. and Diaz,A.<br>Inhibition of inflammatory cytokine production and proliferation in macrophages by Kunitz-type inhibitors from Echinococcus granulosus<br>Mol Biochem Parasitol (2021) 242, 111351-111351. PubMed  Europe PubMed DOI
  8. Santos,B.P.O., Alves,E.S.F., Ferreira,C.S., Ferreira-Silva,A., Goes-Neto,A., Verly,R.M., Liao,L.M., Oliveira,S.C. and de Magalhaes,M.T.Q.<br>Schistocins: Novel antimicrobial peptides encrypted in the Schistosoma mansoni Kunitz Inhibitor SmKI-1<br>Biochim Biophys Acta Gen Subj (2021) 1865, 129989-129989. PubMed  Europe PubMed DOI
  9. Zhang,X., Ni,Y., Guo,K., Dong,Z., Chen,Y., Zhu,H., Xia,Q. and Zhao,P.<br>The mutation of SPI51, a protease inhibitor of silkworm, resulted in the change of antifungal activity during domestication<br>Int J Biol Macromol (2021) 178, 63-70. PubMed  Europe PubMed DOI
    10. 2020
  10. Mrinalini, Koh,C.Y., Li,A.W.L., Bendre,R., Chan,M.Y.Y., Kini,R.M., Benson,M. and Bhattacharya,S.<br>Characterization of a novel inhibitor of coagulation factor XIa identified from salivary gland transcripts of the lone star tick, Amblyomma americanum<br>Toxicon (2020) 177 Suppl 1, S44-S44. PubMed  Europe PubMed DOI
    11. 2019
  11. Banijamali,S.E., Amininasab,M. and Elmi,M.M.<br>Characterization of a new member of kunitz-type protein family from the venom of Persian false-horned viper, Pseudocerastes persicus<br>Arch Biochem Biophys (2019) 662, 1-6. PubMed  Europe PubMed DOI
  12. Banijamali,S.E., Amininasab,M. and Zaeifi,D.<br>Structural characterization of PPTI, a Kunitz-type protein from the venom of Pseudocerastes persicus<br>PLoS ONE (2019) 14, e0214657-e0214657. PubMed  Europe PubMed DOI
  13. Jedlickova,L., Dvorak,J., Hrachovinova,I., Ulrychova,L., Kasny,M. and Mikes,L.<br>A novel Kunitz protein with proposed dual function from Eudiplozoon nipponicum (Monogenea) impairs haemostasis and action of complement in vitro<br>Int J Parasitol (2019) 49, 337-346. PubMed  Europe PubMed DOI
  14. Jin,C., Liu,X.J. and Li,J.L.<br>A Kunitz proteinase inhibitor (HcKuPI) participated in antimicrobial process during pearl sac formation and induced the overgrowth of calcium carbonate in Hyriopsis cumingii<br>Fish Shellfish Immunol (2019) 89, 437-447. PubMed  Europe PubMed DOI
  15. Maria,D.A., Will,S.E.A.L., Bosch,R.V., Souza,J.G., Sciani,J.M., Goldfeder,M.B., Rondon,G.G. and Chudzinski-Tavassi,A.M.<br>Preclinical evaluation of amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity<br>Toxicol Rep (2019) 6, 51-63. PubMed  Europe PubMed DOI  PMC  EPMC
  16. Ranasinghe,S.L., Rivera,V., Boyle,G.M. and McManus,D.P.<br>Kunitz type protease inhibitor from the canine tapeworm as a potential therapeutic for melanoma<br>Sci Rep (2019) 9, 16207-16207. PubMed  Europe PubMed DOI  PMC  EPMC  U
  17. Rogozhin,E.A., Solovyev,M.M., Frolova,T.V. and Izvekova,G.I.<br>Isolation and partial structural characterization of new Kunitz-type trypsin inhibitors from the pike cestode Triaenophorus nodulosus<br>Mol Biochem Parasitol (2019) 233, 111217-111217. PubMed  Europe PubMed DOI
  18. Zhang,X., Guo,K., Dong,Z., Chen,Z., Zhu,H., Zhang,Y., Xia,Q. and Zhao,P.<br>Kunitz-type protease inhibitor BmSPI51 plays an antifungal role in the silkworm cocoon<br>Insect Biochem Mol Biol (2019) , 103258-103258. PubMed  Europe PubMed DOI
    19. 2018
  19. Kaur,S., Devi,A., Saikia,B. and Doley,R.<br>Expression and characterization of flavikunin: a Kunitz-type serine protease inhibitor identified in the venom gland cDNA library of Bungarus flaviceps<br>J Biochem Mol Toxicol (2018) , e22273-e22273. PubMed  Europe PubMed DOI
  20. Morais,S.B., Figueiredo,B.C., Assis,N.R.G., Alvarenga,D.M., de Magalhaes,M.T.Q., Ferreira,R.S., Vieira,A.T., Menezes,G.B. and Oliveira,S.C.<br>Schistosoma mansoni SmKI-1 serine protease inhibitor binds to elastase and impairs neutrophil function and inflammation<br>PLoS Pathog (2018) 14, e1006870-e1006870. PubMed  Europe PubMed DOI
  21. Morais,S.B., Figueiredo,B.C., Assis,N.R.G., Homan,J., Mambelli,F.S., Bicalho,R.M., Souza,C., Martins,V.P., Pinheiro,C.S. and Oliveira,S.C.<br>Schistosoma mansoni SmKI-1 or its C-terminal fragment induces partial protection against S. mansoni infection in mice<br>Front Immunol (2018) 9, 1762-1762. PubMed  Europe PubMed DOI  PMC  EPMC
  22. Ranasinghe,S.L., Boyle,G.M., Fischer,K., Potriquet,J., Mulvenna,J.P. and McManus,D.P.<br>Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer<br>PLoS ONE (2018) 13, e0200433-e0200433. PubMed  Europe PubMed DOI
  23. Sananes,A., Cohen,I., Shahar,A., Hockla,A., De Vita,E., Miller,A.K., Radisky,E.S. and Papo,N.<br>A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering<br>J Biol Chem (2018) 293, 12663-12680. PubMed  Europe PubMed DOI  S
  24. Schmidt,M.C.B., Morais,K.L.P., Almeida,M.E.S., Iqbal,A., Goldfeder,M.B. and Chudzinski-Tavassi,A.M.<br>Amblyomin-X, a recombinant Kunitz-type inhibitor, regulates cell adhesion and migration of human tumor cells<br>Cell Adh Migr (2018) , 1-10. PubMed  Europe PubMed DOI
    25. 2017
  25. Luan,N., Zhou,C., Li,P., Ombati,R., Yan,X., Mo,G., Rong,M., Lai,R., Duan,Z. and Zheng,R.<br>Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi<br>Thromb Haemost (2017) 117, 1031-1039. PubMed  Europe PubMed DOI
  26. Zhang,H., Qiao,R., Gong,H., Cao,J., Zhou,Y. and Zhou,J.<br>Identification and anticoagulant activity of a novel Kunitz-type protein HA11 from the salivary gland of the tick Hyalomma asiaticum<br>Exp Appl Acarol (2017) 71, 71-85. PubMed  Europe PubMed DOI
    27. 2016
  27. Branco,V.G., Iqbal,A., Alvarez-Flores,M.P., Sciani,J.M., de Andrade,S.A., Iwai,L.K., Serrano,S.M. and Chudzinski-Tavassi,A.M.<br>Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo<br>Biochim Biophys Acta (2016) 1864, 1428-1435. PubMed  Europe PubMed DOI
  28. De Souza,J.G., Morais,K.L., Angles-Cano,E., Boufleur,P., de Mello,E.S., Maria,D.A., Origassa,C.S., de Campos Zampolli,H., Camara,N.O., Berra,C.M., Bosch,R.V. and Chudzinski-Tavassi,A.M.<br>Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model<br>Oncotarget (2016) 7, 62255-62266. PubMed  Europe PubMed DOI
  29. Ma,H., Xiao-Peng,T., Yang,S.L., Lu,Q.M. and Lai,R.<br>Protease inhibitor in scorpion (Mesobuthus eupeus) venom prolongs the biological activities of the crude venom<br>Chin J Nat Med (2016) 14, 607-614. PubMed  Europe PubMed DOI
    30. 2015
  30. Bathige,S.D., Umasuthan,N., Godahewa,G.I., Jayasinghe,J.D., Whang,I., Noh,J.K. and Lee,J.<br>A homolog of Kunitz-type serine protease inhibitor from rock bream, Oplegnathus fasciatus: molecular insights and transcriptional modulation in response to microbial and PAMP stimulation, and tissue injury<br>Fish Shellfish Immunol (2015) 46, 285-291. PubMed  Europe PubMed DOI
  31. Boex-Fontvieille,E., Rustgi,S., Reinbothe,S. and Reinbothe,C.<br>A Kunitz-type protease inhibitor regulates programmed cell death during flower development in Arabidopsis thaliana<br>J Exp Bot (2015) 66, 6119-6135. PubMed  Europe PubMed DOI
  32. Ding,L., Wang,X., Liu,H., San,M., Xu,Y., Li,J., Li,S., Cao,Z., Li,W., Wu,Y. and Chen,Z.<br>A new Kunitz-type plasmin inhibitor from scorpion venom<br>Toxicon (2015) 106, 7-13. PubMed  Europe PubMed DOI
  33. Drewes,C.C., Dias,R.Y., Branco,V.G., Cavalcante,M.F., Souza,J.G., Abdalla,D.S., Chudzinski-Tavassi,A.M. and Farsky,S.H.<br>Post-transcriptional control of amblyomin-X on secretion of vascular endothelial growth factor and expression of adhesion molecules in endothelial cells<br>Toxicon (2015) 101, 1-10. PubMed  Europe PubMed DOI
  34. Gladkikh,I., Monastyrnaya,M., Zelepuga,E., Sintsova,O., Tabakmakher,V., Gnedenko,O., Ivanov,A., Hua,K.F. and Kozlovskaya,E.<br>New Kunitz-type HCRG polypeptides from the sea anemone Heteractis crispa<br>Mar Drugs (2015) 13, 6038-6063. PubMed  Europe PubMed DOI
  35. Ranasinghe,S.L., Fischer,K., Gobert,G.N. and McManus,D.P.<br>Functional expression of a novel Kunitz type protease inhibitor from the human blood fluke Schistosoma mansoni<br>Parasit Vectors (2015) 8, 408-408. PubMed  Europe PubMed DOI  PMC  EPMC
  36. Ranasinghe,S.L., Fischer,K., Zhang,W., Gobert,G.N. and McManus,D.P.<br>Cloning and characterization of two potent Kunitz type protease inhibitors from Echinococcus granulosus<br>PLoS Negl Trop Dis (2015) 9, e0004268-e0004268. PubMed  Europe PubMed DOI  PMC  EPMC
    37. 2014
  37. Abreu,P.A., Soares,T.S., Buarque,D.S., Torquato,R.S. and Tanaka,A.S.<br>RmKK, a tissue kallikrein inhibitor from Rhipicephalus microplus eggs<br>Biochem Biophys Res Commun (2014) 449, 69-73. PubMed  Europe PubMed DOI
  38. Cheng,A.C. and Tsai,I.H.<br>Functional characterization of a slow and tight-binding inhibitor of plasmin isolated from Russell's viper venom<br>Biochim Biophys Acta (2014) 1840, 153-159. PubMed  Europe PubMed DOI
  39. Jiang,L., Deng,M., Duan,Z., Tang,X. and Liang,S.<br>Molecular cloning, bioinformatics analysis and functional characterization of HWTX-XI toxin superfamily from the spider Ornithoctonus huwena<br>Peptides (2014) 54, 9-18. PubMed  Europe PubMed DOI
  40. Liu,X.Y., de la Fuente,J., Cote,M., Galindo,R.C., Moutailler,S., Vayssier-Taussat,M. and Bonnet,S.I.<br>IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection<br>PLoS Negl Trop Dis (2014) 8, e2993-e2993. PubMed  Europe PubMed DOI  PMC  EPMC
  41. Mukherjee,A.K., Mackessy,S.P. and Dutta,S.<br>Characterization of a Kunitz-type protease inhibitor peptide (Rusvikunin) purified from Daboia russelii russelii venom<br>Int J Biol Macromol (2014) 67, 154-162. PubMed  Europe PubMed DOI
  42. Mukherjee,A.K. and Mackessy,S.P.<br>Pharmacological properties and pathophysiological significance of a Kunitz-type protease inhibitor (Rusvikunin-II) and its protein complex (Rusvikunin complex) purified from Daboia russelii russelii venom<br>Toxicon (2014) 89, 55-66. PubMed  Europe PubMed DOI
  43. Pasqualoto,K.F., Balan,A., Barreto,S.A., Simons,S.M. and Chudzinski-Tavassi,A.M.<br>Structural findings and molecular modeling approach of a TFPI-like inhibitor<br>Protein Pept Lett (2014) 21, 452-457. PubMed  Europe PubMed DOI
  44. Wan,H., Kim,B.Y., Lee,K.S., Yoon,H.J., Lee,K.Y. and Jin,B.R.<br>A bumblebee (Bombus ignitus) venom serine protease inhibitor that acts as a microbial serine protease inhibitor<br>Comp Biochem Physiol B Biochem Mol Biol (2014) 167, 59-64. PubMed  Europe PubMed DOI
    45. 2013
  45. Cao,J., Shi,L., Zhou,Y., Gao,X., Zhang,H., Gong,H. and Zhou,J.<br>Characterization of a new Kunitz-type serine protease inhibitor from the hard tick Rhipicephalus hemaphysaloides<br>Arch Insect Biochem Physiol (2013) 84, 104-113. PubMed  Europe PubMed DOI
  46. Chen,Z., Cao,Z., Li,W. and Wu,Y.<br>Cloning and characterization of a novel Kunitz-type inhibitor from scorpion with unique cysteine framework<br>Toxicon (2013) 72, 5-10. PubMed  Europe PubMed DOI
  47. Kong,H.J., Lee,Y.J., Park,I.S., Lee,W.W., Kim,Y.O., Nam,B.H., Kim,W.J., Jung,H., Jeon,Y.J., An,C.M. and Lee,S.J.<br>Molecular and functional characterizations of a Kunitz-type serine protease inhibitor FcKuSPI of the shrimp Fenneropenaeus chinensis<br>Fish Shellfish Immunol (2013) 35, 1025-1029. PubMed  Europe PubMed DOI
  48. Louw,E., van der Merwe,N.A., Neitz,A.W. and Maritz-Olivier,C.<br>Evolution of the tissue factor pathway inhibitor-like Kunitz domain-containing protein family in Rhipicephalus microplus<br>Int J Parasitol (2013) 43, 81-94. PubMed  Europe PubMed DOI
  49. Narasimhan,S., Perez,O., Mootien,S., Deponte,K., Koski,R.A., Fikrig,E. and Ledizet,M.<br>Characterization of ixophilin, a thrombin inhibitor from the gut of Ixodes scapularis<br>PLoS ONE (2013) 8, e68012-e68012. PubMed  Europe PubMed DOI  PMC  EPMC
  50. Qiu,Y., Lee,K.S., Choo,Y.M., Kong,D., Yoon,H.J. and Jin,B.R.<br>Molecular cloning and antifibrinolytic activity of a serine protease inhibitor from bumblebee (Bombus terrestris) venom<br>Toxicon (2013) 63, 1-6. PubMed  Europe PubMed DOI
  51. Toubarro,D., Avila,M.M., Montiel,R. and Simoes,N.<br>A pathogenic nematode targets recognition proteins to avoid insect defenses<br>PLoS ONE (2013) 8, e75691-e75691. PubMed  Europe PubMed DOI  PMC  EPMC
  52. Ventura,J.S., Faria,F., Batista,I.F., Simons,S.M., Oliveira,D.G., Morais,K.L. and Chudzinski-Tavassi,A.M.<br>A Kunitz-type FXa inhibitor affects tumor progression, hypercoagulable state and triggers apoptosis<br>Biomed Pharmacother (2013) 67, 192-196. PubMed  Europe PubMed DOI  U
  53. Wan,H., Lee,K.S., Kim,B.Y., Yuan,M., Zhan,S., You,H., Li,J. and Jin,B.R.<br>A spider (Araneus ventricosus) chymotrypsin inhibitor that acts as an elastase inhibitor and a microbial serine protease inhibitor<br>Comp Biochem Physiol B Biochem Mol Biol (2013) 165, 36-41. PubMed  Europe PubMed DOI
  54. Wan,H., Lee,K.S., Kim,B.Y., Zou,F.M., Yoon,H.J., Je,Y.H., Li,J. and Jin,B.R.<br>A spider-derived Kunitz-type serine protease inhibitor that acts as a plasmin inhibitor and an elastase inhibitor<br>PLoS ONE (2013) 8, e53343-e53343. PubMed  Europe PubMed DOI  PMC  EPMC
    55. 2012
  55. Alim,M.A., Islam,M.K., Anisuzzaman, Miyoshi,T., Hatta,T., Yamaji,K., Matsubayashi,M., Fujisaki,K. and Tsuji,N.<br>A hemocyte-derived Kunitz-BPTI-type chymotrypsin inhibitor, HlChI, from the ixodid tick Haemaphysalis longicornis, plays regulatory functions in tick blood-feeding processes<br>Insect Biochem Mol Biol (2012) 42, 925-934. PubMed  Europe PubMed DOI
  56. Andreotti,R., Cunha,R.C., Soares,M.A., Guerrero,F.D., Leivas Leite,F.P. and Perez de Leon,A.A.<br>Protective immunity against tick infestation in cattle vaccinated with recombinant trypsin inhibitor of Rhipicephalus microplus<br>Vaccine (2012) 30, 6678-6685. PubMed  Europe PubMed DOI
  57. Cheng,A.C., Wu,H.L., Shi,G.Y. and Tsai,I.H.<br>A novel heparin-dependent inhibitor of activated protein C that potentiates consumptive coagulopathy in Russell's viper envenomation<br>J Biol Chem (2012) 287, 15739-15748. PubMed  Europe PubMed DOI
  58. Choo,Y.M., Yoon,H.J. and Jin,B.R.<br>Effects of the bumblebee (Bombus ignitus) venom serine protease inhibitor on serine protease and phospholipase A<br>J Asia-Pac Entomol (2012) 15, 543-545. DOI
  59. Choo,Y.M., Lee,K.S., Yoon,H.J., Qiu,Y., Wan,H., Sohn,M.R., Sohn,H.D. and Jin,B.R.<br>Antifibrinolytic role of a bee venom serine protease inhibitor that acts as a plasmin inhibitor<br>PLoS ONE (2012) 7, e32269-e32269. PubMed  Europe PubMed DOI  PMC  EPMC
  60. Isaeva,M.P., Chausova,V.E., Zelepuga,E.A., Guzev,K.V., Tabakmakher,V.M., Monastyrnaya,M.M. and Kozlovskaya,E.P.<br>A new multigene superfamily of Kunitz-type protease inhibitors from sea anemone Heteractis crispa<br>Peptides (2012) 34, 88-97. PubMed  Europe PubMed DOI
  61. Wang,H., Wang,L., Zhou,M., Yang,M., Ma,C., Chen,T., Zhang,Y., Zeller,M., Hornshaw,M. and Shaw,C.<br>Functional peptidomics of amphibian skin secretion: a novel Kunitz-type chymotrypsin inhibitor from the African hyperoliid frog, Kassina senegalensis<br>Biochimie (2012) 94, 891-899. PubMed  Europe PubMed DOI
  62. Wei,X., Yang,J., Yang,J., Liu,X., Liu,M., Yang,D., Xu,J. and Hu,X.<br>A four-domain Kunitz-type proteinase inhibitor from Solen grandis is implicated in immune response<br>Fish Shellfish Immunol (2012) 33, 1276-1284. PubMed  Europe PubMed DOI
    63. 2011
  63. Gao,X., Shi,L., Zhou,Y., Cao,J., Zhang,H. and Zhou,J.<br>Characterization of the anticoagulant protein rhipilin-1 from the Rhipicephalus haemaphysaloides tick<br>J Insect Physiol (2011) 57, 339-343. PubMed  Europe PubMed DOI
  64. Peigneur,S., Billen,B., Derua,R., Waelkens,E., Debaveye,S., Beress,L. and Tytgat,J.<br>A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties<br>Biochem Pharmacol (2011) 82, 81-90. PubMed  Europe PubMed DOI
  65. Ramazanova,A.S., Fil'Kin,S.Yu., Starkov,V.G. and Utkin,Y.<br>Molecular cloning and sequence analysis of cDNAs coding for a serine proteinase and a Kunitz-type inhibitor in the venom gland of the Vipera nikolskii viper<br>Russ J Bioorg Chem (2011) 37, 333-343. DOI
  66. Zhao,R., Dai,H., Qiu,S., Li,T., He,Y., Ma,Y., Chen,Z., Wu,Y., Li,W. and Cao,Z.<br>SdPI, the first functionally characterized Kunitz-type trypsin inhibitor from scorpion venom<br>PLoS ONE (2011) 6, e27548-e27548. PubMed  Europe PubMed DOI  PMC  EPMC
    67. 2010
  67. Cicardi,M., Levy,R.J., McNeil,D.L., Li,H.H., Sheffer,A.L., Campion,M., Horn,P.T. and Pullman,W.E.<br>Ecallantide for the treatment of acute attacks in hereditary angioedema<br>N Engl J Med (2010) 363, 523-531. PubMed  Europe PubMed DOI
  68. Dreon,M.S., Ituarte,S. and Heras,H.<br>The role of the proteinase inhibitor ovorubin in apple snail eggs resembles plant embryo defense against predation<br>PLoS ONE (2010) 5, e15059-e15059. PubMed  Europe PubMed DOI  PMC  EPMC
  69. Miyoshi,T., Tsuji,N., Islam,M.K., Alim,M.A., Hatta,T., Yamaji,K., Anisuzzaman and Fujisaki,K.<br>A Kunitz-type proteinase inhibitor from the midgut of the ixodid tick, Haemaphysalis longicornis, and its endogenous target serine proteinase<br>Mol Biochem Parasitol (2010) 170, 112-115. PubMed  Europe PubMed DOI
  70. Stolz,L.E. and Horn,P.T.<br>Ecallantide: A plasma kallikrein inhibitor for the treatment of acute attacks of hereditary angioedema<br>Drugs Today (Barc) (2010) 46, 547-555. PubMed  Europe PubMed DOI
    71. 2009
  71. Gonzalez,S., Flo,M., Margenat,M., Duran,R., Gonzalez-Sapienza,G., Grana,M., Parkinson,J., Maizels,R.M., Salinas,G., Alvarez,B. and Fernandez,C.<br>A family of diverse Kunitz inhibitors from Echinococcus granulosus potentially involved in host-parasite cross-talk<br>PLoS ONE (2009) 4, e7009-e7009. PubMed  Europe PubMed DOI  PMC  EPMC
  72. Islam,M.K., Tsuji,N., Miyoshi,T., Alim,M.A., Huang,X., Hatta,T. and Fujisaki,K.<br>The Kunitz-like modulatory protein haemangin is vital for hard tick blood-feeding success<br>PLoS Pathog (2009) 5, e1000497-e1000497. PubMed  Europe PubMed DOI  PMC  EPMC
  73. Viswanathan,M., Comeau,S.R. and Ladner,R.C.<br>Engineered protein protease inhibitors<br>Curr Enzyme Inhib (2009) 5, 87-98.  V
  74. Yang,X., Wang,Y., Lu,Z., Zhai,L., Jiang,J., Liu,J. and Yu,H.<br>A novel serine protease inhibitor from the venom of Vespa bicolor Fabricius<br>Comp Biochem Physiol B Biochem Mol Biol (2009) 153, 116-120. PubMed  Europe PubMed DOI
    75. 2008
  75. Chen,D., He,N. and Zhang,M.<br>[Expression of a shrimp Kunitz-type protease inhibitor in Pichia pastoris and activity analysis]<br>Sheng Wu Gong Cheng Xue Bao (2008) 24, 500-503. PubMed  Europe PubMed  E
  76. Frank,M.M. and Jiang,H.<br>New therapies for hereditary angioedema: disease outlook changes dramatically<br>J Allergy Clin Immunol (2008) 121, 272-280. PubMed  Europe PubMed DOI  V
  77. Honma,T., Kawahata,S., Ishida,M., Nagai,H., Nagashima,Y. and Shiomi,K.<br>Novel peptide toxins from the sea anemone Stichodactyla haddoni<br>Peptides (2008) 29, 536-544. PubMed  Europe PubMed DOI
  78. Lu,J., Yang,H., Yu,H., Gao,W., Lai,R., Liu,J. and Liang,X.<br>A novel serine protease inhibitor from Bungarus fasciatus venom<br>Peptides (2008) 29, 369-374. PubMed  Europe PubMed DOI
  79. Lu,X.Y., Wang,A.L., Yang,H.L. and Lai,R.<br>A novel trypsin inhibitor from Bungarus fasciatus venom<br>Chin J Nat Med (2008) 6, 153-158. DOI
  80. Minagawa,S., Sugiyama,M., Ishida,M., Nagashima,Y. and Shiomi,K.<br>Kunitz-type protease inhibitors from acrorhagi of three species of sea anemones<br>Comp Biochem Physiol B Biochem Mol Biol (2008) 150, 240-245. PubMed  Europe PubMed DOI
    81. 2007
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