Literature for family I2 unassigned peptidases

(Topics flags: S Structure, T Target, E Expression, V Review, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

2026
1. Oyama,H. and Inagaki,H.
   Discovery and Functional Characterization of Kunitz-Type Toxins from the Tetrodotoxin-Bearing Flatworm Planocera Multitencaculata
   Mar Biotechnol (NY) (2026) 28, 10-10. PubMed  Europe PubMed DOI
2025
2. Jin,C., Zhang,J., Tan,X., Wei,F., Bai,Z. and Luo,W.
   Glycine-rich Kunitz-type Serine Protease Inhibitor (HcGrKuSPI) Prevents Extracellular Degradation of Matrix Proteins during Shell Formation in Hyriopsis Cumingii
   Mar Biotechnol (NY) (2025) 27, 160-160. PubMed  Europe PubMed DOI
2024
3. Flo Diaz,M., Pellizza,L., Duran,R., Alvarez,B. and Fernandez,C.
   The monodomain Kunitz protein EgKU-7 from Echinococcus granulosus, the dog tapeworm, is a high-affinity trypsin inhibitor with two interaction sites
   Biochem J (2024) 481, 717-739. PubMed  Europe PubMed DOI
4. Zhang,X., Jiang,W., Guo,K., Guo,Z., Duan,J., Jing,X., Xia,Q. and Zhao,P.
   A mutation in the Bombyx mori BmSPI51 gene results in alterations protein abundance in cocoon and unveils compensatory mechanism of silk gland proteinase inhibitors
   Int J Biol Macromol (2024) , 137001-137001. PubMed  Europe PubMed DOI
2023
5. Xu,W., Rustenhoven,J., Nelson,C.A., Dykstra,T., Ferreiro,A., Papadopoulos,Z., Burnham,C.D., Dantas,G., Fremont,D.H. and Kipnis,J.
   A novel immune modulator IM33 mediates a glia-gut-neuronal axis that controls lifespan
   Neuron (2023) 111, 3244-3254. PubMed  Europe PubMed DOI  PMC  EPMC
2022
6. Shen,C., Zhang,M., Liang,H., He,J., Zhang,B. and Liang,B.
   Gene cloning and functional study of PmKSPI from Pinctada fucata martensii
   Fish Shellfish Immunol (2022) 131, 1157-1165. PubMed  Europe PubMed DOI
2021
7. Sagasti,C., Casaravilla,C., Fernandez,C., Flo,M. and Diaz,A.
   Inhibition of inflammatory cytokine production and proliferation in macrophages by Kunitz-type inhibitors from Echinococcus granulosus
   Mol Biochem Parasitol (2021) 242, 111351-111351. PubMed  Europe PubMed DOI
8. Santos,B.P.O., Alves,E.S.F., Ferreira,C.S., Ferreira-Silva,A., Goes-Neto,A., Verly,R.M., Liao,L.M., Oliveira,S.C. and de Magalhaes,M.T.Q.
   Schistocins: Novel antimicrobial peptides encrypted in the Schistosoma mansoni Kunitz Inhibitor SmKI-1
   Biochim Biophys Acta Gen Subj (2021) 1865, 129989-129989. PubMed  Europe PubMed DOI
9. Zhang,X., Ni,Y., Guo,K., Dong,Z., Chen,Y., Zhu,H., Xia,Q. and Zhao,P.
   The mutation of SPI51, a protease inhibitor of silkworm, resulted in the change of antifungal activity during domestication
   Int J Biol Macromol (2021) 178, 63-70. PubMed  Europe PubMed DOI
2020
10. Mrinalini, Koh,C.Y., Li,A.W.L., Bendre,R., Chan,M.Y.Y., Kini,R.M., Benson,M. and Bhattacharya,S.
    Characterization of a novel inhibitor of coagulation factor XIa identified from salivary gland transcripts of the lone star tick, Amblyomma americanum
    Toxicon (2020) 177 Suppl 1, S44-S44. PubMed  Europe PubMed DOI
2019
11. Banijamali,S.E., Amininasab,M. and Elmi,M.M.
    Characterization of a new member of kunitz-type protein family from the venom of Persian false-horned viper, Pseudocerastes persicus
    Arch Biochem Biophys (2019) 662, 1-6. PubMed  Europe PubMed DOI
12. Banijamali,S.E., Amininasab,M. and Zaeifi,D.
    Structural characterization of PPTI, a Kunitz-type protein from the venom of Pseudocerastes persicus
    PLoS ONE (2019) 14, e0214657-e0214657. PubMed  Europe PubMed DOI
13. Jedlickova,L., Dvorak,J., Hrachovinova,I., Ulrychova,L., Kasny,M. and Mikes,L.
    A novel Kunitz protein with proposed dual function from Eudiplozoon nipponicum (Monogenea) impairs haemostasis and action of complement in vitro
    Int J Parasitol (2019) 49, 337-346. PubMed  Europe PubMed DOI
14. Jin,C., Liu,X.J. and Li,J.L.
    A Kunitz proteinase inhibitor (HcKuPI) participated in antimicrobial process during pearl sac formation and induced the overgrowth of calcium carbonate in Hyriopsis cumingii
    Fish Shellfish Immunol (2019) 89, 437-447. PubMed  Europe PubMed DOI
15. Maria,D.A., Will,S.E.A.L., Bosch,R.V., Souza,J.G., Sciani,J.M., Goldfeder,M.B., Rondon,G.G. and Chudzinski-Tavassi,A.M.
    Preclinical evaluation of amblyomin-X, a Kunitz-type protease inhibitor with antitumor activity
    Toxicol Rep (2019) 6, 51-63. PubMed  Europe PubMed DOI  PMC  EPMC
16. Ranasinghe,S.L., Rivera,V., Boyle,G.M. and McManus,D.P.
    Kunitz type protease inhibitor from the canine tapeworm as a potential therapeutic for melanoma
    Sci Rep (2019) 9, 16207-16207. PubMed  Europe PubMed DOI  PMC  EPMC  U
17. Rogozhin,E.A., Solovyev,M.M., Frolova,T.V. and Izvekova,G.I.
    Isolation and partial structural characterization of new Kunitz-type trypsin inhibitors from the pike cestode Triaenophorus nodulosus
    Mol Biochem Parasitol (2019) 233, 111217-111217. PubMed  Europe PubMed DOI
18. Zhang,X., Guo,K., Dong,Z., Chen,Z., Zhu,H., Zhang,Y., Xia,Q. and Zhao,P.
    Kunitz-type protease inhibitor BmSPI51 plays an antifungal role in the silkworm cocoon
    Insect Biochem Mol Biol (2019) , 103258-103258. PubMed  Europe PubMed DOI
2018
19. Kaur,S., Devi,A., Saikia,B. and Doley,R.
    Expression and characterization of flavikunin: a Kunitz-type serine protease inhibitor identified in the venom gland cDNA library of Bungarus flaviceps
    J Biochem Mol Toxicol (2018) , e22273-e22273. PubMed  Europe PubMed DOI
20. Morais,S.B., Figueiredo,B.C., Assis,N.R.G., Alvarenga,D.M., de Magalhaes,M.T.Q., Ferreira,R.S., Vieira,A.T., Menezes,G.B. and Oliveira,S.C.
    Schistosoma mansoni SmKI-1 serine protease inhibitor binds to elastase and impairs neutrophil function and inflammation
    PLoS Pathog (2018) 14, e1006870-e1006870. PubMed  Europe PubMed DOI
21. Morais,S.B., Figueiredo,B.C., Assis,N.R.G., Homan,J., Mambelli,F.S., Bicalho,R.M., Souza,C., Martins,V.P., Pinheiro,C.S. and Oliveira,S.C.
    Schistosoma mansoni SmKI-1 or its C-terminal fragment induces partial protection against S. mansoni infection in mice
    Front Immunol (2018) 9, 1762-1762. PubMed  Europe PubMed DOI  PMC  EPMC
22. Ranasinghe,S.L., Boyle,G.M., Fischer,K., Potriquet,J., Mulvenna,J.P. and McManus,D.P.
    Kunitz type protease inhibitor EgKI-1 from the canine tapeworm Echinococcus granulosus as a promising therapeutic against breast cancer
    PLoS ONE (2018) 13, e0200433-e0200433. PubMed  Europe PubMed DOI
23. Sananes,A., Cohen,I., Shahar,A., Hockla,A., De Vita,E., Miller,A.K., Radisky,E.S. and Papo,N.
    A potent, proteolysis-resistant inhibitor of kallikrein-related peptidase 6 (KLK6) for cancer therapy, developed by combinatorial engineering
    J Biol Chem (2018) 293, 12663-12680. PubMed  Europe PubMed DOI  S
24. Schmidt,M.C.B., Morais,K.L.P., Almeida,M.E.S., Iqbal,A., Goldfeder,M.B. and Chudzinski-Tavassi,A.M.
    Amblyomin-X, a recombinant Kunitz-type inhibitor, regulates cell adhesion and migration of human tumor cells
    Cell Adh Migr (2018) , 1-10. PubMed  Europe PubMed DOI
2017
25. Luan,N., Zhou,C., Li,P., Ombati,R., Yan,X., Mo,G., Rong,M., Lai,R., Duan,Z. and Zheng,R.
    Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi
    Thromb Haemost (2017) 117, 1031-1039. PubMed  Europe PubMed DOI
26. Zhang,H., Qiao,R., Gong,H., Cao,J., Zhou,Y. and Zhou,J.
    Identification and anticoagulant activity of a novel Kunitz-type protein HA11 from the salivary gland of the tick Hyalomma asiaticum
    Exp Appl Acarol (2017) 71, 71-85. PubMed  Europe PubMed DOI
2016
27. Branco,V.G., Iqbal,A., Alvarez-Flores,M.P., Sciani,J.M., de Andrade,S.A., Iwai,L.K., Serrano,S.M. and Chudzinski-Tavassi,A.M.
    Amblyomin-X having a Kunitz-type homologous domain, is a noncompetitive inhibitor of FXa and induces anticoagulation in vitro and in vivo
    Biochim Biophys Acta (2016) 1864, 1428-1435. PubMed  Europe PubMed DOI
28. De Souza,J.G., Morais,K.L., Angles-Cano,E., Boufleur,P., de Mello,E.S., Maria,D.A., Origassa,C.S., de Campos Zampolli,H., Camara,N.O., Berra,C.M., Bosch,R.V. and Chudzinski-Tavassi,A.M.
    Promising pharmacological profile of a Kunitz-type inhibitor in murine renal cell carcinoma model
    Oncotarget (2016) 7, 62255-62266. PubMed  Europe PubMed DOI
29. Ma,H., Xiao-Peng,T., Yang,S.L., Lu,Q.M. and Lai,R.
    Protease inhibitor in scorpion (Mesobuthus eupeus) venom prolongs the biological activities of the crude venom
    Chin J Nat Med (2016) 14, 607-614. PubMed  Europe PubMed DOI
2015
30. Bathige,S.D., Umasuthan,N., Godahewa,G.I., Jayasinghe,J.D., Whang,I., Noh,J.K. and Lee,J.
    A homolog of Kunitz-type serine protease inhibitor from rock bream, Oplegnathus fasciatus: molecular insights and transcriptional modulation in response to microbial and PAMP stimulation, and tissue injury
    Fish Shellfish Immunol (2015) 46, 285-291. PubMed  Europe PubMed DOI
31. Boex-Fontvieille,E., Rustgi,S., Reinbothe,S. and Reinbothe,C.
    A Kunitz-type protease inhibitor regulates programmed cell death during flower development in Arabidopsis thaliana
    J Exp Bot (2015) 66, 6119-6135. PubMed  Europe PubMed DOI
32. Ding,L., Wang,X., Liu,H., San,M., Xu,Y., Li,J., Li,S., Cao,Z., Li,W., Wu,Y. and Chen,Z.
    A new Kunitz-type plasmin inhibitor from scorpion venom
    Toxicon (2015) 106, 7-13. PubMed  Europe PubMed DOI
33. Drewes,C.C., Dias,R.Y., Branco,V.G., Cavalcante,M.F., Souza,J.G., Abdalla,D.S., Chudzinski-Tavassi,A.M. and Farsky,S.H.
    Post-transcriptional control of amblyomin-X on secretion of vascular endothelial growth factor and expression of adhesion molecules in endothelial cells
    Toxicon (2015) 101, 1-10. PubMed  Europe PubMed DOI
34. Gladkikh,I., Monastyrnaya,M., Zelepuga,E., Sintsova,O., Tabakmakher,V., Gnedenko,O., Ivanov,A., Hua,K.F. and Kozlovskaya,E.
    New Kunitz-type HCRG polypeptides from the sea anemone Heteractis crispa
    Mar Drugs (2015) 13, 6038-6063. PubMed  Europe PubMed DOI
35. Ranasinghe,S.L., Fischer,K., Gobert,G.N. and McManus,D.P.
    Functional expression of a novel Kunitz type protease inhibitor from the human blood fluke Schistosoma mansoni
    Parasit Vectors (2015) 8, 408-408. PubMed  Europe PubMed DOI  PMC  EPMC
36. Ranasinghe,S.L., Fischer,K., Zhang,W., Gobert,G.N. and McManus,D.P.
    Cloning and characterization of two potent Kunitz type protease inhibitors from Echinococcus granulosus
    PLoS Negl Trop Dis (2015) 9, e0004268-e0004268. PubMed  Europe PubMed DOI  PMC  EPMC
2014
37. Abreu,P.A., Soares,T.S., Buarque,D.S., Torquato,R.S. and Tanaka,A.S.
    RmKK, a tissue kallikrein inhibitor from Rhipicephalus microplus eggs
    Biochem Biophys Res Commun (2014) 449, 69-73. PubMed  Europe PubMed DOI
38. Cheng,A.C. and Tsai,I.H.
    Functional characterization of a slow and tight-binding inhibitor of plasmin isolated from Russell's viper venom
    Biochim Biophys Acta (2014) 1840, 153-159. PubMed  Europe PubMed DOI
39. Jiang,L., Deng,M., Duan,Z., Tang,X. and Liang,S.
    Molecular cloning, bioinformatics analysis and functional characterization of HWTX-XI toxin superfamily from the spider Ornithoctonus huwena
    Peptides (2014) 54, 9-18. PubMed  Europe PubMed DOI
40. Liu,X.Y., de la Fuente,J., Cote,M., Galindo,R.C., Moutailler,S., Vayssier-Taussat,M. and Bonnet,S.I.
    IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection
    PLoS Negl Trop Dis (2014) 8, e2993-e2993. PubMed  Europe PubMed DOI  PMC  EPMC
41. Mukherjee,A.K., Mackessy,S.P. and Dutta,S.
    Characterization of a Kunitz-type protease inhibitor peptide (Rusvikunin) purified from Daboia russelii russelii venom
    Int J Biol Macromol (2014) 67, 154-162. PubMed  Europe PubMed DOI
42. Mukherjee,A.K. and Mackessy,S.P.
    Pharmacological properties and pathophysiological significance of a Kunitz-type protease inhibitor (Rusvikunin-II) and its protein complex (Rusvikunin complex) purified from Daboia russelii russelii venom
    Toxicon (2014) 89, 55-66. PubMed  Europe PubMed DOI
43. Pasqualoto,K.F., Balan,A., Barreto,S.A., Simons,S.M. and Chudzinski-Tavassi,A.M.
    Structural findings and molecular modeling approach of a TFPI-like inhibitor
    Protein Pept Lett (2014) 21, 452-457. PubMed  Europe PubMed DOI
44. Wan,H., Kim,B.Y., Lee,K.S., Yoon,H.J., Lee,K.Y. and Jin,B.R.
    A bumblebee (Bombus ignitus) venom serine protease inhibitor that acts as a microbial serine protease inhibitor
    Comp Biochem Physiol B Biochem Mol Biol (2014) 167, 59-64. PubMed  Europe PubMed DOI
2013
45. Cao,J., Shi,L., Zhou,Y., Gao,X., Zhang,H., Gong,H. and Zhou,J.
    Characterization of a new Kunitz-type serine protease inhibitor from the hard tick Rhipicephalus hemaphysaloides
    Arch Insect Biochem Physiol (2013) 84, 104-113. PubMed  Europe PubMed DOI
46. Chen,Z., Cao,Z., Li,W. and Wu,Y.
    Cloning and characterization of a novel Kunitz-type inhibitor from scorpion with unique cysteine framework
    Toxicon (2013) 72, 5-10. PubMed  Europe PubMed DOI
47. Kong,H.J., Lee,Y.J., Park,I.S., Lee,W.W., Kim,Y.O., Nam,B.H., Kim,W.J., Jung,H., Jeon,Y.J., An,C.M. and Lee,S.J.
    Molecular and functional characterizations of a Kunitz-type serine protease inhibitor FcKuSPI of the shrimp Fenneropenaeus chinensis
    Fish Shellfish Immunol (2013) 35, 1025-1029. PubMed  Europe PubMed DOI
48. Louw,E., van der Merwe,N.A., Neitz,A.W. and Maritz-Olivier,C.
    Evolution of the tissue factor pathway inhibitor-like Kunitz domain-containing protein family in Rhipicephalus microplus
    Int J Parasitol (2013) 43, 81-94. PubMed  Europe PubMed DOI
49. Narasimhan,S., Perez,O., Mootien,S., Deponte,K., Koski,R.A., Fikrig,E. and Ledizet,M.
    Characterization of ixophilin, a thrombin inhibitor from the gut of Ixodes scapularis
    PLoS ONE (2013) 8, e68012-e68012. PubMed  Europe PubMed DOI  PMC  EPMC
50. Qiu,Y., Lee,K.S., Choo,Y.M., Kong,D., Yoon,H.J. and Jin,B.R.
    Molecular cloning and antifibrinolytic activity of a serine protease inhibitor from bumblebee (Bombus terrestris) venom
    Toxicon (2013) 63, 1-6. PubMed  Europe PubMed DOI
51. Toubarro,D., Avila,M.M., Montiel,R. and Simoes,N.
    A pathogenic nematode targets recognition proteins to avoid insect defenses
    PLoS ONE (2013) 8, e75691-e75691. PubMed  Europe PubMed DOI  PMC  EPMC
52. Ventura,J.S., Faria,F., Batista,I.F., Simons,S.M., Oliveira,D.G., Morais,K.L. and Chudzinski-Tavassi,A.M.
    A Kunitz-type FXa inhibitor affects tumor progression, hypercoagulable state and triggers apoptosis
    Biomed Pharmacother (2013) 67, 192-196. PubMed  Europe PubMed DOI  U
53. Wan,H., Lee,K.S., Kim,B.Y., Yuan,M., Zhan,S., You,H., Li,J. and Jin,B.R.
    A spider (Araneus ventricosus) chymotrypsin inhibitor that acts as an elastase inhibitor and a microbial serine protease inhibitor
    Comp Biochem Physiol B Biochem Mol Biol (2013) 165, 36-41. PubMed  Europe PubMed DOI
54. Wan,H., Lee,K.S., Kim,B.Y., Zou,F.M., Yoon,H.J., Je,Y.H., Li,J. and Jin,B.R.
    A spider-derived Kunitz-type serine protease inhibitor that acts as a plasmin inhibitor and an elastase inhibitor
    PLoS ONE (2013) 8, e53343-e53343. PubMed  Europe PubMed DOI  PMC  EPMC
2012
55. Alim,M.A., Islam,M.K., Anisuzzaman, Miyoshi,T., Hatta,T., Yamaji,K., Matsubayashi,M., Fujisaki,K. and Tsuji,N.
    A hemocyte-derived Kunitz-BPTI-type chymotrypsin inhibitor, HlChI, from the ixodid tick Haemaphysalis longicornis, plays regulatory functions in tick blood-feeding processes
    Insect Biochem Mol Biol (2012) 42, 925-934. PubMed  Europe PubMed DOI
56. Andreotti,R., Cunha,R.C., Soares,M.A., Guerrero,F.D., Leivas Leite,F.P. and Perez de Leon,A.A.
    Protective immunity against tick infestation in cattle vaccinated with recombinant trypsin inhibitor of Rhipicephalus microplus
    Vaccine (2012) 30, 6678-6685. PubMed  Europe PubMed DOI
57. Cheng,A.C., Wu,H.L., Shi,G.Y. and Tsai,I.H.
    A novel heparin-dependent inhibitor of activated protein C that potentiates consumptive coagulopathy in Russell's viper envenomation
    J Biol Chem (2012) 287, 15739-15748. PubMed  Europe PubMed DOI
58. Choo,Y.M., Yoon,H.J. and Jin,B.R.
    Effects of the bumblebee (Bombus ignitus) venom serine protease inhibitor on serine protease and phospholipase A
    J Asia-Pac Entomol (2012) 15, 543-545. DOI
59. Choo,Y.M., Lee,K.S., Yoon,H.J., Qiu,Y., Wan,H., Sohn,M.R., Sohn,H.D. and Jin,B.R.
    Antifibrinolytic role of a bee venom serine protease inhibitor that acts as a plasmin inhibitor
    PLoS ONE (2012) 7, e32269-e32269. PubMed  Europe PubMed DOI  PMC  EPMC
60. Isaeva,M.P., Chausova,V.E., Zelepuga,E.A., Guzev,K.V., Tabakmakher,V.M., Monastyrnaya,M.M. and Kozlovskaya,E.P.
    A new multigene superfamily of Kunitz-type protease inhibitors from sea anemone Heteractis crispa
    Peptides (2012) 34, 88-97. PubMed  Europe PubMed DOI
61. Wang,H., Wang,L., Zhou,M., Yang,M., Ma,C., Chen,T., Zhang,Y., Zeller,M., Hornshaw,M. and Shaw,C.
    Functional peptidomics of amphibian skin secretion: a novel Kunitz-type chymotrypsin inhibitor from the African hyperoliid frog, Kassina senegalensis
    Biochimie (2012) 94, 891-899. PubMed  Europe PubMed DOI
62. Wei,X., Yang,J., Yang,J., Liu,X., Liu,M., Yang,D., Xu,J. and Hu,X.
    A four-domain Kunitz-type proteinase inhibitor from Solen grandis is implicated in immune response
    Fish Shellfish Immunol (2012) 33, 1276-1284. PubMed  Europe PubMed DOI
2011
63. Gao,X., Shi,L., Zhou,Y., Cao,J., Zhang,H. and Zhou,J.
    Characterization of the anticoagulant protein rhipilin-1 from the Rhipicephalus haemaphysaloides tick
    J Insect Physiol (2011) 57, 339-343. PubMed  Europe PubMed DOI
64. Peigneur,S., Billen,B., Derua,R., Waelkens,E., Debaveye,S., Beress,L. and Tytgat,J.
    A bifunctional sea anemone peptide with Kunitz type protease and potassium channel inhibiting properties
    Biochem Pharmacol (2011) 82, 81-90. PubMed  Europe PubMed DOI
65. Ramazanova,A.S., Fil'Kin,S.Yu., Starkov,V.G. and Utkin,Y.
    Molecular cloning and sequence analysis of cDNAs coding for a serine proteinase and a Kunitz-type inhibitor in the venom gland of the Vipera nikolskii viper
    Russ J Bioorg Chem (2011) 37, 333-343. DOI
66. Zhao,R., Dai,H., Qiu,S., Li,T., He,Y., Ma,Y., Chen,Z., Wu,Y., Li,W. and Cao,Z.
    SdPI, the first functionally characterized Kunitz-type trypsin inhibitor from scorpion venom
    PLoS ONE (2011) 6, e27548-e27548. PubMed  Europe PubMed DOI  PMC  EPMC
2010
67. Cicardi,M., Levy,R.J., McNeil,D.L., Li,H.H., Sheffer,A.L., Campion,M., Horn,P.T. and Pullman,W.E.
    Ecallantide for the treatment of acute attacks in hereditary angioedema
    N Engl J Med (2010) 363, 523-531. PubMed  Europe PubMed DOI
68. Dreon,M.S., Ituarte,S. and Heras,H.
    The role of the proteinase inhibitor ovorubin in apple snail eggs resembles plant embryo defense against predation
    PLoS ONE (2010) 5, e15059-e15059. PubMed  Europe PubMed DOI  PMC  EPMC
69. Miyoshi,T., Tsuji,N., Islam,M.K., Alim,M.A., Hatta,T., Yamaji,K., Anisuzzaman and Fujisaki,K.
    A Kunitz-type proteinase inhibitor from the midgut of the ixodid tick, Haemaphysalis longicornis, and its endogenous target serine proteinase
    Mol Biochem Parasitol (2010) 170, 112-115. PubMed  Europe PubMed DOI
70. Stolz,L.E. and Horn,P.T.
    Ecallantide: A plasma kallikrein inhibitor for the treatment of acute attacks of hereditary angioedema
    Drugs Today (Barc) (2010) 46, 547-555. PubMed  Europe PubMed DOI
2009
71. Gonzalez,S., Flo,M., Margenat,M., Duran,R., Gonzalez-Sapienza,G., Grana,M., Parkinson,J., Maizels,R.M., Salinas,G., Alvarez,B. and Fernandez,C.
    A family of diverse Kunitz inhibitors from Echinococcus granulosus potentially involved in host-parasite cross-talk
    PLoS ONE (2009) 4, e7009-e7009. PubMed  Europe PubMed DOI  PMC  EPMC
72. Islam,M.K., Tsuji,N., Miyoshi,T., Alim,M.A., Huang,X., Hatta,T. and Fujisaki,K.
    The Kunitz-like modulatory protein haemangin is vital for hard tick blood-feeding success
    PLoS Pathog (2009) 5, e1000497-e1000497. PubMed  Europe PubMed DOI  PMC  EPMC
73. Viswanathan,M., Comeau,S.R. and Ladner,R.C.
    Engineered protein protease inhibitors
    Curr Enzyme Inhib (2009) 5, 87-98.  V
74. Yang,X., Wang,Y., Lu,Z., Zhai,L., Jiang,J., Liu,J. and Yu,H.
    A novel serine protease inhibitor from the venom of Vespa bicolor Fabricius
    Comp Biochem Physiol B Biochem Mol Biol (2009) 153, 116-120. PubMed  Europe PubMed DOI
2008
75. Chen,D., He,N. and Zhang,M.
    [Expression of a shrimp Kunitz-type protease inhibitor in Pichia pastoris and activity analysis]
    Sheng Wu Gong Cheng Xue Bao (2008) 24, 500-503. PubMed  Europe PubMed  E
76. Frank,M.M. and Jiang,H.
    New therapies for hereditary angioedema: disease outlook changes dramatically
    J Allergy Clin Immunol (2008) 121, 272-280. PubMed  Europe PubMed DOI  V
77. Honma,T., Kawahata,S., Ishida,M., Nagai,H., Nagashima,Y. and Shiomi,K.
    Novel peptide toxins from the sea anemone Stichodactyla haddoni
    Peptides (2008) 29, 536-544. PubMed  Europe PubMed DOI
78. Lu,J., Yang,H., Yu,H., Gao,W., Lai,R., Liu,J. and Liang,X.
    A novel serine protease inhibitor from Bungarus fasciatus venom
    Peptides (2008) 29, 369-374. PubMed  Europe PubMed DOI
79. Lu,X.Y., Wang,A.L., Yang,H.L. and Lai,R.
    A novel trypsin inhibitor from Bungarus fasciatus venom
    Chin J Nat Med (2008) 6, 153-158. DOI
80. Minagawa,S., Sugiyama,M., Ishida,M., Nagashima,Y. and Shiomi,K.
    Kunitz-type protease inhibitors from acrorhagi of three species of sea anemones
    Comp Biochem Physiol B Biochem Mol Biol (2008) 150, 240-245. PubMed  Europe PubMed DOI
2007
81. Devy,L., Rabbani,S.A., Stochl,M., Ruskowski,M., Mackie,I., Naa,L., Toews,M., van Gool,R., Chen,J., Ley,A., Ladner,R.C., Dransfield,D.T. and Henderikx,P.
    PEGylated DX-1000: pharmacokinetics and antineoplastic activity of a specific plasmin inhibitor
    Neoplasia (2007) 9, 927-937. PubMed  Europe PubMed DOI  PMC  EPMC
82. Zhao,P., Xia,Q., Li,J., Fujii,H., Banno,Y. and Xiang,Z.
    Purification, characterization and cloning of a chymotrypsin inhibitor (CI-9) from the hemolymph of the silkworm, Bombyx mori
    Protein J (2007) 26, 349-357. PubMed  Europe PubMed DOI
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