IPD-NHKIR

Release 1.1.0.1 (2018-06-21) build 13

The database provides a centralised repository for non-human KIR (NHKIR) sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC.

This work is made possible by support from The Pirbright Institute, the BBSRC, and Anthony Nolan.

Developers

Development of the NHKIR Database has been undertaken by the following individuals:

Anthony Nolan Research Institute

  • James Robinson
  • Steven GE Marsh

Stanford University Medical School

  • Libby Guethlein
  • Peter Parham

The Pirbright Institute

  • Giuseppe Maccari
  • John Hammond

Official Species Designations

Full details of all the species included in IPD-NHKIR and their official designations are available here. If you are working on non-human KIR nomenclature and your species is not represented above please contact us. Nomenclature committees representing different species or groups should also contact IPD Support for further information about the inclusion of their sequences into the IPD-NHKIR Database.