Welcome to IPD-KIR
Release 2.12 (2022-12) Version Report - Build
The IPD-KIR Database provides a centralised repository for human KIR sequences. Killer-cell Immunoglobulin-like Receptors (KIR) have been shown to be highly polymorphic at the allelic and haplotypic level. KIRs are members of the immunoglobulin superfamily (IgSF) formerly called Killer-cell Inhibitory Receptors. They are composed of two or three Ig-domains, a transmembrane region and cytoplasmic tail which can in turn be short (activatory) or long (inhibitory). The Leukocyte Receptor Complex (LRC) which encodes KIR genes has been shown to be polymorphic, polygenic and complex like the MHC. For more information about the database and what data and tools are available please see our about page. This work was supported by National Institutes of Health Grant P01-CA-111412.
Alignment
The alignment tool provides access to pre-compiled alignments for individual KIR genes and sequence features
Alleles
Query the IPD-KIR database for officially named alleles with the allele query tool.
Statistics
Latest IPD-KIR statistics and release reports
Download
Access to the IPD-KIR ftp for downloading sequence files
Matching
KIR-Ligand, DPB T-Cell Epitope + HLA-B Leader matching tools
Cells
Perform complex queries on the IPD cell database
Tools
A complete list of tools for querying the IPD-KIR Database
Submit
Submit a sequence to the IPD-KIR Database
Latest Developments
Recent developments of the IPD database include
- New query tools and API - Please see individual pages for more information
- Latest Publication:
Robinson, J., Halliwell, J.A., McWilliam, H., Lopez, R. and Marsh, S.G.E.
IPD -- the Immuno-Polymorphism Database.
Nucleic Acids Research (2013) 41:D1234-40. Download PDF
Disclaimer
Where discrepancies have arisen between reported sequences and those stored in the databases, the original authors have been contacted where possible, and necessary amendments to published sequences have been incorporated. Future sequencing may identify errors and the Nomenclature Committees would welcome any evidence that helps to maintain the accuracy of the database. We therefore make no warranties regarding the correctness of the data, and disclaim liability for damages resulting from its use. We cannot provide unrestricted permission regarding the use of the data, as some data may be covered by patents or other rights. Any medical or genetic information is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.