Protein Panel

Gene-level detail: domains and sequence

The Protein Information panel sits at the bottom of the discovery platform and shows the detail of a single gene. It fills in when you click a gene (CDS) in the region plot of either the Reference or Compare iBGC card. The panel is collapsible — open it when you want to verify a cluster’s enzymatic machinery gene by gene.

The Protein Information panel: gene summary, the InterPro/Pfam domain hits, and the copyable amino-acid sequence.

What it shows

Summary

Field Meaning
Cluster Representative The representative protein this gene maps to, with an outbound link where available.
Protein Length Length in amino acids.
Gene Caller The gene-prediction tool that called the gene.
Strand + or −.
Start / End Coordinates on the contig.
ChemOnt Class When predicted: the ChemOnt chemical class for this protein, with its probability and weight.

InterPro annotations

A table of the protein’s domain hits — the functional units that make this gene part of a biosynthetic cluster:

  • Accession — the InterPro/signature accession (links to InterPro).
  • Description — what the domain is.
  • GO Slim — a coarse functional category for the domain.
  • Start / End — where the domain falls within the protein.
  • E-value — the match confidence.

These domain hits are the same annotations the platform uses to compare clusters and to compute novelty, so this table is where you confirm why a cluster was scored or matched the way it was.

Protein sequence

The full amino-acid sequence, with a Copy button so you can paste it straight into a sequence search, an alignment, or a primer-design tool.

Why this matters

For a natural product chemist, the domain table is the most direct read on what a cluster can make. Seeing, for example, a run of ketosynthase / acyltransferase / dehydratase domains confirms a polyketide assembly line; adenylation and condensation domains point to non-ribosomal peptides. The panel lets you go from a scored candidate to the concrete enzymatic evidence behind it.