iBGC Detail
The Reference and Compare panels
When you select an iBGC, its detail card appears on the right of the discovery platform. There are two such cards, with identical layouts:
- Reference (top) — the iBGC you pin with right-click → Set as reference iBGC. It stays put while you browse other candidates.
- Compare (middle) — updates every time you left-click an iBGC in the roster or on a map.
Together they let you hold one cluster fixed and read others against it.
What the card shows
Header
The iBGC accession, a Reference / Compare badge, a Type Strain badge where applicable, and an actions menu (set as reference, find similar, add to shortlist).
Attribute chips
A row of chips summarises the cluster:
| Chip | Meaning |
|---|---|
| assembly | Parent assembly accession — links out to its source page when available. |
| class | The normalised BGC class. |
| status | validated (experimentally characterised reference) or candidate. |
| completeness | complete, or partial if the cluster runs off the contig edge. |
| GCF | The gene cluster family path (e.g. 42.7.3). Click it to filter the whole discovery platform to that family and its descendants. |
| Novelty | Distance from the nearest validated cluster. |
| Domain Novelty | Fraction of domains unique within the GCF. |
| compound features | Count of predicted/curated compound features. Hover for the list; click to open the structure in MolView when a SMILES is available. |
Location and sources
A line gives the contig, the cluster’s start–end coordinates and size, the number of source BGC predictions it consolidates, and the tools that produced them.
Region plot
A gene-level diagram of the cluster: each arrow is a protein-coding gene (CDS). Click any gene to load its protein — sequence and domain annotations — into the Protein Information panel at the bottom of the discovery platform.
Compound features in detail
The “compound features” chip combines two kinds of chemistry prediction, shown in its hover tooltip:
- Curated compounds — for validated iBGCs, the named product(s) and their natural-product class path (from sources such as MIBiG).
- CHAMOIS ChemOnt classes — chemical classes predicted from the cluster’s proteins and aggregated across its genes, shown as a small tree with the number of contributing genes and a confidence percentage. See ChemOnt.
Using the two panels together
A typical comparison:
- Find a promising cluster and right-click → Set as reference iBGC. It pins to the top.
- Left-click through similar candidates (or use Find similar iBGCs); each loads into the Compare card.
- Read class, GCF, novelty, size, and predicted chemistry against the reference.
- Click into individual genes to confirm the domain architecture in the protein panel.
- Add the keepers to your shortlist.