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CHEBI:8499 - propranolol
| Formula | C16H21NO2 |
| Net Charge | 0 |
| Average Mass | 259.349 |
| Monoisotopic Mass | 259.15723 |
| SMILES | CC(C)NCC(O)COc1cccc2ccccc12 |
| InChI | InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3 |
| InChIKey | AQHHHDLHHXJYJD-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | blood serum (BTO:0000133) | MetaboLights (MTBLS90) |
| Roles Classification |
|---|
| Chemical Roles: | environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. human blood serum metabolite Any metabolite (endogenous or exogenous) found in human blood serum samples. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. |
| Applications: | ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. hyperglycemic agent A drug which increases the blood glucose level. beta-adrenergic antagonist An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety. antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. renoprotective agent Any compound that is able to prevent damage to the kidneys. vasoconstrictor agent Drug used to cause constriction of the blood vessels. nootropic agent Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration. vasodilator agent A drug used to cause dilation of the blood vessels. vulnerary A drug used in treating and healing of wounds. hepatoprotective agent Any compound that is able to prevent damage to the liver. anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. antihypertensive agent Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. hypoglycemic agent A drug which lowers the blood glucose level. anti-asthmatic agent Any compound that has anti-asthmatic effects. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. bone density conservation agent An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis. anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| propranolol (CHEBI:8499) has functional parent 1-naphthol (CHEBI:10319) |
| propranolol (CHEBI:8499) has role analgesic (CHEBI:35480) |
| propranolol (CHEBI:8499) has role anti-anaemic agent (CHEBI:75835) |
| propranolol (CHEBI:8499) has role anti-arrhythmia drug (CHEBI:38070) |
| propranolol (CHEBI:8499) has role anti-asthmatic agent (CHEBI:65023) |
| propranolol (CHEBI:8499) has role antidepressant (CHEBI:35469) |
| propranolol (CHEBI:8499) has role antihypertensive agent (CHEBI:35674) |
| propranolol (CHEBI:8499) has role antineoplastic agent (CHEBI:35610) |
| propranolol (CHEBI:8499) has role anxiolytic drug (CHEBI:35474) |
| propranolol (CHEBI:8499) has role bone density conservation agent (CHEBI:50646) |
| propranolol (CHEBI:8499) has role cardiovascular drug (CHEBI:35554) |
| propranolol (CHEBI:8499) has role environmental contaminant (CHEBI:78298) |
| propranolol (CHEBI:8499) has role hepatoprotective agent (CHEBI:62868) |
| propranolol (CHEBI:8499) has role human blood serum metabolite (CHEBI:85234) |
| propranolol (CHEBI:8499) has role hyperglycemic agent (CHEBI:76916) |
| propranolol (CHEBI:8499) has role hypoglycemic agent (CHEBI:35526) |
| propranolol (CHEBI:8499) has role neuroprotective agent (CHEBI:63726) |
| propranolol (CHEBI:8499) has role nootropic agent (CHEBI:66980) |
| propranolol (CHEBI:8499) has role ophthalmology drug (CHEBI:66981) |
| propranolol (CHEBI:8499) has role renoprotective agent (CHEBI:231911) |
| propranolol (CHEBI:8499) has role vasoconstrictor agent (CHEBI:50514) |
| propranolol (CHEBI:8499) has role vasodilator agent (CHEBI:35620) |
| propranolol (CHEBI:8499) has role vulnerary (CHEBI:73336) |
| propranolol (CHEBI:8499) has role xenobiotic (CHEBI:35703) |
| propranolol (CHEBI:8499) has role β-adrenergic antagonist (CHEBI:35530) |
| propranolol (CHEBI:8499) is a naphthalenes (CHEBI:25477) |
| propranolol (CHEBI:8499) is a propanolamine (CHEBI:35533) |
| propranolol (CHEBI:8499) is a secondary amine (CHEBI:32863) |
| Incoming Relation(s) |
| propranolol hydrochloride (CHEBI:8500) has part propranolol (CHEBI:8499) |
| (R)-(+)-propranolol (CHEBI:8736) is a propranolol (CHEBI:8499) |
| IUPAC Name |
|---|
| 3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol |
| INNs | Source |
|---|---|
| propranolol | WHO MedNet |
| propranolol | ChemIDplus |
| propranolol | WHO MedNet |
| propranololum | WHO MedNet |
| Synonyms | Source |
|---|---|
| 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanol | ChemIDplus |
| 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol | IUPAC |
| AY-64043- | ChEMBL |
| .beta.-propranolol | ChEMBL |
| Inderide-40/25 | ChEMBL |
| Inderide-80/25 | ChEMBL |
| Manual Xrefs | Databases |
|---|---|
| 2303 | DrugCentral |
| C07407 | KEGG COMPOUND |
| D08443 | KEGG DRUG |
| DB00571 | DrugBank |
| HMDB0001849 | HMDB |
| LSM-4329 | LINCS |
| Propranolol | Wikipedia |
| Citations |
|---|