CHEBI:8736 - (R)-(+)-propranolol

ChEBI IDCHEBI:8736
ChEBI Name(R)-(+)-propranolol
Stars
ASCII Name(R)-(+)-propranolol
Last Modified25 February 2016
DownloadsMolfile
FormulaC16H21NO2
Net Charge0
Average Mass259.349
Monoisotopic Mass259.15723
SMILESCC(C)NC[C@@H](O)COc1cccc2ccccc12
InChIInChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3/t14-/m1/s1
InChIKeyAQHHHDLHHXJYJD-CQSZACIVSA-N
Roles Classification
Chemical Roles:
environmental contaminant  Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
xenobiotic  A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
human blood serum metabolite  Any metabolite (endogenous or exogenous) found in human blood serum samples.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
Applications:
ophthalmology drug  Any compound used for the treatment of eye conditions or eye diseases.
hyperglycemic agent  A drug which increases the blood glucose level.
beta-adrenergic antagonist  An agent that binds to but does not activate β-adrenergic receptors thereby blocking the actions of endogenous or exogenous β-adrenergic agonists. β-Adrenergic antagonists are used for treatment of hypertension, cardiac arrhythmias, angina pectoris, glaucoma, migraine headaches and anxiety.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
renoprotective agent  Any compound that is able to prevent damage to the kidneys.
vasoconstrictor agent  Drug used to cause constriction of the blood vessels.
nootropic agent  Any compound that improves mental functions such as cognition, memory, intelligence, motivation, attention, and concentration.
vasodilator agent  A drug used to cause dilation of the blood vessels.
vulnerary  A drug used in treating and healing of wounds.
hepatoprotective agent  Any compound that is able to prevent damage to the liver.
anti-arrhythmia drug  A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres.
antihypertensive agent  Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism.
anti-anaemic agent  A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
hypoglycemic agent  A drug which lowers the blood glucose level.
anti-asthmatic agent  Any compound that has anti-asthmatic effects.
cardiovascular drug  A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume.
bone density conservation agent  An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis.
anxiolytic drug  Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
ChEBI Ontology
Outgoing Relation(s)
(R)-(+)-propranolol (CHEBI:8736) is a propranolol (CHEBI:8499)
Incoming Relation(s)
dexpropranolol hydrochloride (CHEBI:51161) has part (R)-(+)-propranolol (CHEBI:8736)
IUPAC Name 
(2R)-3-(naphthalen-1-yloxy)-1-(propan-2-ylamino)propan-2-ol
INNs  Source
dexpropranololWHO MedNet
dexpropranololChEBI
dexpropranololumWHO MedNet
Synonyms  Source
(+)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanolChemIDplus
2R-PropranololChemIDplus
DexpropranololKEGG COMPOUND
DextropropranololChemIDplus
D-PropranololChemIDplus
(+)-PropranololChemIDplus
Manual XrefsDatabases
C11193KEGG COMPOUND
DB00571DrugBank
LSM-5972LINCS
Registry NumbersSources
Beilstein:4140099Beilstein
CAS:5051-22-9KEGG COMPOUND
CAS:5051-22-9ChemIDplus