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CHEBI:72596 - papulacandin

ChEBI IDCHEBI:72596
ChEBI Namepapulacandin
Stars
DefinitionAny of the carbohydrate-containing antibiotic compounds obtained from the deuteromycetous fungus Papularia sphaerosperma and generally consisting of o-orsellinic acid linked via a spirocyclic structure to a lactose moiety with two different side-chains: a shorter fatty-acid chain at the O-(6') position and a longer side-chain at the O-(3) position of the glucose moiety. Papulacandin D, the simplest member of the papulacandin family, lacks the O-(6'-acyl-β-galactoside) at the O-(4) position of the glucose residue. The papulacandins show potent antifungal activity against Candida albicans, Geotrichum lactis, Saccharomyces cerevisiae, and Pneumocytis carinii, but are inactive against filamentous fungi, bacteria, and protazoa.
Last Modified27 February 2013
SubmitterGareth Owen
Roles Classification
Biological Role:
antimicrobial agent  A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
ChEBI Ontology
Outgoing Relation(s)
papulacandin (CHEBI:72596) has functional parent o-orsellinic acid (CHEBI:32807)
papulacandin (CHEBI:72596) is a C-glycosyl compound (CHEBI:20857)
papulacandin (CHEBI:72596) is a 2-benzofurans (CHEBI:38831)
papulacandin (CHEBI:72596) is a carbohydrate-containing antibiotic (CHEBI:23007)
papulacandin (CHEBI:72596) is a fatty acid ester (CHEBI:35748)
papulacandin (CHEBI:72596) is a spiroketal (CHEBI:72600)
Incoming Relation(s)
papulacandin A (CHEBI:72611) is a papulacandin (CHEBI:72596)
papulacandin B (CHEBI:569624) is a papulacandin (CHEBI:72596)
papulacandin C (CHEBI:72622) is a papulacandin (CHEBI:72596)
papulacandin D (CHEBI:72630) is a papulacandin (CHEBI:72596)
Synonym  Source
papulacandinsChEBI
Citations