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CHEBI:59692 - cycrimine

Default Structure
ChEBI IDCHEBI:59692
ChEBI Namecycrimine
Stars
DefinitionA member of the class of piperidines that is 3-(piperidin-1-yl)propan-1-ol in which one of the hydrogen atoms at the 1-position is substituted by cyclopentyl, and the other is substituted by phenyl. A central anticholinergic, it is used as its hydrochloride salt in the management and treatment of Parkinson's disease.
Last Modified22 February 2017
SubmitterGareth Owen
DownloadsMolfile
FormulaC19H29NO
Net Charge0
Average Mass287.447
Monoisotopic Mass287.22491
SMILESOC(CCN1CCCCC1)(c1ccccc1)C1CCCC1
InChIInChI=1S/C19H29NO/c21-19(18-11-5-6-12-18,17-9-3-1-4-10-17)13-16-20-14-7-2-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2
InChIKeySWRUZBWLEWHWRI-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
Applications:
antiparkinson drug  A drug used in the treatment of Parkinson's disease.
muscarinic antagonist  A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
antidyskinesia agent  Any compound which can be used to treat or alleviate the symptoms of dyskinesia.
ChEBI Ontology
Outgoing Relation(s)
cycrimine (CHEBI:59692) has role antidyskinesia agent (CHEBI:66956)
cycrimine (CHEBI:59692) has role antiparkinson drug (CHEBI:48407)
cycrimine (CHEBI:59692) has role muscarinic antagonist (CHEBI:48876)
cycrimine (CHEBI:59692) is a piperidines (CHEBI:26151)
cycrimine (CHEBI:59692) is a tertiary alcohol (CHEBI:26878)
cycrimine (CHEBI:59692) is a tertiary amino compound (CHEBI:50996)
Incoming Relation(s)
cycrimine hydrochloride (CHEBI:59693) has part cycrimine (CHEBI:59692)
(R)-cycrimine (CHEBI:59706) is a cycrimine (CHEBI:59692)
(S)-cycrimine (CHEBI:59707) is a cycrimine (CHEBI:59692)
IUPAC Name 
1-cyclopentyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol
INNs  Source
cicriminaChemIDplus
cycrimineWHO MedNet
cycrimineChemIDplus
cycriminumChemIDplus
Synonyms  Source
(±)-cycrimineChEBI
α-cyclopentyl-α-phenyl-1-piperidinepropanolNIST Chemistry WebBook
Manual XrefsDatabases
763DrugCentral
CycrimineWikipedia
DB00942DrugBank
Registry NumbersSources
Reaxys:245788Reaxys
CAS:77-39-4NIST Chemistry WebBook
CAS:77-39-4ChemIDplus
Citations