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CHEBI:59062 - polymyxin
| ChEBI ID | CHEBI:59062 |
| ChEBI Name | polymyxin |
| Stars | |
| Definition | Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria. |
| Last Modified | 17 June 2015 |
| Submitter | Steve |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| polymyxin (CHEBI:59062) has role antibacterial agent (CHEBI:33282) |
| polymyxin (CHEBI:59062) has role antimicrobial agent (CHEBI:33281) |
| polymyxin (CHEBI:59062) is a heterodetic cyclic peptide (CHEBI:24533) |
| polymyxin (CHEBI:59062) is a lipopeptide (CHEBI:46895) |
| Incoming Relation(s) |
| colistimethate (CHEBI:59662) is a polymyxin (CHEBI:59062) |
| colistimethate A (CHEBI:59669) is a polymyxin (CHEBI:59062) |
| colistimethate B (CHEBI:59671) is a polymyxin (CHEBI:59062) |
| colistimethate sodium (CHEBI:34650) is a polymyxin (CHEBI:59062) |
| colistin (CHEBI:37943) is a polymyxin (CHEBI:59062) |
| colistin A (CHEBI:59064) is a polymyxin (CHEBI:59062) |
| colistin A sodium methanesulfonate (CHEBI:59663) is a polymyxin (CHEBI:59062) |
| colistin B (CHEBI:59673) is a polymyxin (CHEBI:59062) |
| colistin B sodium methanesulfonate (CHEBI:59664) is a polymyxin (CHEBI:59062) |
| polymyxin B1 (CHEBI:8309) is a polymyxin (CHEBI:59062) |
| polymyxin B2 (CHEBI:59063) is a polymyxin (CHEBI:59062) |
| Synonyms | Source |
|---|---|
| polymyxins | ChEBI |
| polymixin | ChEBI |
| polymycin | ChEBI |