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CHEBI:57248 - echinocandin
| ChEBI ID | CHEBI:57248 |
| ChEBI Name | echinocandin |
| Stars | |
| Definition | Any one of a family of large lipopeptides that are inhibitors of the enzyme 1,3-β-glucan synthase, thus damaging fungal cell walls. Echinocandins are fungicidal against most Candida spp and fungistatic against Aspergillus spp. |
| Last Modified | 16 April 2024 |
| Submitter | Marcus Ennis |
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of 1,3-β-glucan synthase (EC 2.4.1.34). antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| echinocandin (CHEBI:57248) has role EC 2.4.1.34 (1,3-β-glucan synthase) inhibitor (CHEBI:230471) |
| echinocandin (CHEBI:57248) is a antibiotic antifungal agent (CHEBI:86478) |
| echinocandin (CHEBI:57248) is a lipopeptide (CHEBI:46895) |
| Incoming Relation(s) |
| acrophiarin (CHEBI:167054) is a echinocandin (CHEBI:57248) |
| aminocandin (CHEBI:84073) is a echinocandin (CHEBI:57248) |
| anidulafungin (CHEBI:55346) is a echinocandin (CHEBI:57248) |
| caspofungin (CHEBI:474180) is a echinocandin (CHEBI:57248) |
| cilofungin (CHEBI:315019) is a echinocandin (CHEBI:57248) |
| echinocandin B (CHEBI:315018) is a echinocandin (CHEBI:57248) |
| micafungin (CHEBI:600520) is a echinocandin (CHEBI:57248) |
| pneumocandin B0 (CHEBI:131609) is a echinocandin (CHEBI:57248) |
| rezafungin (CHEBI:229680) is a echinocandin (CHEBI:57248) |
| rezafungin acetate (CHEBI:230470) is a echinocandin (CHEBI:57248) |
| Synonym | Source |
|---|---|
| echinocandins | ChEBI |