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CHEBI:5130 - flurbiprofen
| Formula | C15H13FO2 |
| Net Charge | 0 |
| Average Mass | 244.265 |
| Monoisotopic Mass | 244.08996 |
| SMILES | CC(C(=O)O)c1ccc(-c2ccccc2)c(F)c1 |
| InChI | InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18) |
| InChIKey | SYTBZMRGLBWNTM-UHFFFAOYSA-N |
| Wikipedia |
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| Roles Classification |
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| Chemical Role: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| Applications: | antirheumatic drug A drug used to treat rheumatoid arthritis. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. hypoglycemic agent A drug which lowers the blood glucose level. non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| flurbiprofen (CHEBI:5130) has functional parent propionic acid (CHEBI:30768) |
| flurbiprofen (CHEBI:5130) has parent hydride biphenyl (CHEBI:17097) |
| flurbiprofen (CHEBI:5130) has role analgesic (CHEBI:35480) |
| flurbiprofen (CHEBI:5130) has role anti-anaemic agent (CHEBI:75835) |
| flurbiprofen (CHEBI:5130) has role anti-HIV agent (CHEBI:64946) |
| flurbiprofen (CHEBI:5130) has role antibacterial agent (CHEBI:33282) |
| flurbiprofen (CHEBI:5130) has role antipyretic (CHEBI:35493) |
| flurbiprofen (CHEBI:5130) has role antirheumatic drug (CHEBI:35842) |
| flurbiprofen (CHEBI:5130) has role EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor (CHEBI:35544) |
| flurbiprofen (CHEBI:5130) has role hypoglycemic agent (CHEBI:35526) |
| flurbiprofen (CHEBI:5130) has role non-narcotic analgesic (CHEBI:35481) |
| flurbiprofen (CHEBI:5130) has role non-steroidal anti-inflammatory drug (CHEBI:35475) |
| flurbiprofen (CHEBI:5130) has role ophthalmology drug (CHEBI:66981) |
| flurbiprofen (CHEBI:5130) is a fluorobiphenyl (CHEBI:38679) |
| flurbiprofen (CHEBI:5130) is a monocarboxylic acid (CHEBI:25384) |
| Incoming Relation(s) |
| nitroflurbiprofen (CHEBI:77428) has functional parent flurbiprofen (CHEBI:5130) |
| (R)-flurbiprofen (CHEBI:38666) is a flurbiprofen (CHEBI:5130) |
| (S)-flurbiprofen (CHEBI:42446) is a flurbiprofen (CHEBI:5130) |
| IUPAC Name |
|---|
| 2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid |
| INNs | Source |
|---|---|
| flurbiprofene | WHO MedNet |
| flurbiprofeno | WHO MedNet |
| Synonyms | Source |
|---|---|
| 2-(2-fluorobiphenyl-4-yl)propanoic acid | ChEBI |
| 2-fluoro-α-methyl-(1,1'-biphenyl)-4-acetic acid | ChemIDplus |
| (±)-2-fluoro-α-methyl-4-biphenylacetic acid | ChemIDplus |
| 3-fluoro-4-phenylhydratropic acid | ChemIDplus |
| Ansaid | ChemIDplus |
| BTS 18,322 | ChEMBL |
| Brand Names | Source |
|---|---|
| Cebutid | ChEMBL |
| Froben | ChEMBL |
| Froben sr | ChEMBL |
| Strefen | ChEMBL |
| Transact | ChEMBL |
| Citations |
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