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CHEBI:38666 - (R)-flurbiprofen

Default Structure
ChEBI IDCHEBI:38666
ChEBI Name(R)-flurbiprofen
Stars
ASCII Name(R)-flurbiprofen
Last Modified17 October 2009
SubmitterKirill Degtyarenko
DownloadsMolfile
FormulaC15H13FO2
Net Charge0
Average Mass244.265
Monoisotopic Mass244.08996
SMILESC[C@@H](C(=O)O)c1ccc(-c2ccccc2)c(F)c1
InChIInChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1
InChIKeySYTBZMRGLBWNTM-SNVBAGLBSA-N
Roles Classification
Chemical Roles:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
anti-HIV agent  An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus.
antibacterial agent  A substance (or active part thereof) that kills or slows the growth of bacteria.
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor  A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
anti-anaemic agent  A compound which increases either the number of red cells or the amount of haemoglobin in the blood.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
antirheumatic drug  A drug used to treat rheumatoid arthritis.
analgesic  An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms.
hypoglycemic agent  A drug which lowers the blood glucose level.
antipyretic  A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
ophthalmology drug  Any compound used for the treatment of eye conditions or eye diseases.
ChEBI Ontology
Outgoing Relation(s)
(R)-flurbiprofen (CHEBI:38666) has role antineoplastic agent (CHEBI:35610)
(R)-flurbiprofen (CHEBI:38666) is a flurbiprofen (CHEBI:5130)
(R)-flurbiprofen (CHEBI:38666) is enantiomer of (S)-flurbiprofen (CHEBI:42446)
Incoming Relation(s)
(S)-flurbiprofen (CHEBI:42446) is enantiomer of (R)-flurbiprofen (CHEBI:38666)
IUPAC Name 
(2R)-2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid
INN  Source
tarenflurbiloWHO MedNet
Synonyms  Source
(−)-(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acidChemIDplus
(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acidChEBI
E-7869ChEMBL
Flurbiprofen, (r)-ChEMBL
FlurizanChemIDplus
(R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acidChemIDplus
Registry NumbersSources
Beilstein:4686157Beilstein
Beilstein:5745751Beilstein
CAS:51543-40-9ChemIDplus
Citations