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CHEBI:38666 - (R)-flurbiprofen

ChEBI IDCHEBI:38666
ChEBI Name(R)-flurbiprofen
Stars
ASCII Name(R)-flurbiprofen
Last Modified17 October 2009
SubmitterKirill Degtyarenko
DownloadsMolfile
FormulaC15H13FO2
Net Charge0
Average Mass244.265
Monoisotopic Mass244.08996
SMILESC[C@@H](C(=O)O)c1ccc(-c2ccccc2)c(F)c1
InChIInChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1
InChIKeySYTBZMRGLBWNTM-SNVBAGLBSA-N
Roles Classification
Chemical Roles:
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Bronsted acid  A molecular entity capable of donating a hydron to an acceptor (Brønsted base).
Biological Roles:
EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor  A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Applications:
antipyretic  A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
non-steroidal anti-inflammatory drug  An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic  A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
ChEBI Ontology
Outgoing Relation(s)
(R)-flurbiprofen (CHEBI:38666) is a flurbiprofen (CHEBI:5130)
(R)-flurbiprofen (CHEBI:38666) is enantiomer of (S)-flurbiprofen (CHEBI:42446)
Incoming Relation(s)
(S)-flurbiprofen (CHEBI:42446) is enantiomer of (R)-flurbiprofen (CHEBI:38666)
IUPAC Name 
(2R)-2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid
Synonyms  Source
TarenflurbilChemIDplus
(−)-(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acidChemIDplus
FlurizanChemIDplus
(R)-2-fluoro-α-methyl(1,1'-biphenyl)-4-acetic acidChemIDplus
(2R)-2-(2-fluorobiphenyl-4-yl)propanoic acidChEBI
Registry NumbersSources
Beilstein:4686157Beilstein
Beilstein:5745751Beilstein
CAS:51543-40-9ChemIDplus