EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:42446 - (S)-flurbiprofen
| Formula | C15H13FO2 |
| Net Charge | 0 |
| Average Mass | 244.265 |
| Monoisotopic Mass | 244.08996 |
| SMILES | C[C@H](C(=O)O)c1ccc(-c2ccccc2)c(F)c1 |
| InChI | InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m0/s1 |
| InChIKey | SYTBZMRGLBWNTM-JTQLQIEISA-N |
| Roles Classification |
|---|
| Chemical Roles: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| Applications: | non-steroidal anti-inflammatory drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. antipyretic A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. antirheumatic drug A drug used to treat rheumatoid arthritis. analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. hypoglycemic agent A drug which lowers the blood glucose level. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. ophthalmology drug Any compound used for the treatment of eye conditions or eye diseases. non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| (S)-flurbiprofen (CHEBI:42446) is a flurbiprofen (CHEBI:5130) |
| (S)-flurbiprofen (CHEBI:42446) is enantiomer of (R)-flurbiprofen (CHEBI:38666) |
| Incoming Relation(s) |
| (R)-flurbiprofen (CHEBI:38666) is enantiomer of (S)-flurbiprofen (CHEBI:42446) |
| IUPAC Name |
|---|
| (2S)-2-(2-fluoro-[1,1'-biphenyl-4-yl])propanoic acid |
| INNs | Source |
|---|---|
| esflurbiprofene | WHO MedNet |
| esflurbiprofeno | WHO MedNet |
| Synonyms | Source |
|---|---|
| (2S)-2-(2-fluorobiphenyl-4-yl)propanoic acid | ChEBI |
| BTS 24332 | ChEMBL |
| BTS-24332 | ChEMBL |
| esflurbiprofen | ChemIDplus |
| esflurbiprofen | ChEMBL |
| FLURBIPROFEN | PDBeChem |
| Registry Numbers | Sources |
|---|---|
| Beilstein:4686156 | Beilstein |
| CAS:51543-39-6 | ChemIDplus |
| Citations |
|---|