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CHEBI:51032 - epinastine

ChEBI IDCHEBI:51032
ChEBI Nameepinastine
Stars
DefinitionA benzazepine that is 6,11-dihydro-5H-dibenzo[b,e]azepine in which the azepine ring is fused to the e side of 4,5-dihydro-1H-imidazol-2-amine.
Last Modified22 February 2017
SubmitterInma Spiteri
DownloadsMolfile
FormulaC16H15N3
Net Charge0
Average Mass249.317
Monoisotopic Mass249.12660
SMILESNC1=NCC2c3ccccc3Cc3ccccc3N12
InChIInChI=1S/C16H15N3/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16/h1-8,15H,9-10H2,(H2,17,18)
InChIKeyWHWZLSFABNNENI-UHFFFAOYSA-N
Wikipedia
Roles Classification
Biological Roles:
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
histamine antagonist  Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
Applications:
anti-allergic agent  A drug used to treat allergic reactions.
H1-receptor antagonist  H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
histamine antagonist  Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
ophthalmology drug  Any compound used for the treatment of eye conditions or eye diseases.
ChEBI Ontology
Outgoing Relation(s)
epinastine (CHEBI:51032) has role anti-allergic agent (CHEBI:50857)
epinastine (CHEBI:51032) has role H1-receptor antagonist (CHEBI:37955)
epinastine (CHEBI:51032) has role histamine antagonist (CHEBI:37956)
epinastine (CHEBI:51032) has role ophthalmology drug (CHEBI:66981)
epinastine (CHEBI:51032) is a benzazepine (CHEBI:35676)
epinastine (CHEBI:51032) is a guanidines (CHEBI:24436)
Incoming Relation(s)
epinastine hydrochloride (CHEBI:51037) has part epinastine (CHEBI:51032)
R-epinastine (CHEBI:51035) is a epinastine (CHEBI:51032)
S-epinastine (CHEBI:51036) is a epinastine (CHEBI:51032)
IUPAC Name 
9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine
INNs  Source
epinastineChemIDplus
epinastinaChemIDplus
épinastineChemIDplus
epinastinumChemIDplus
Synonyms  Source
3-amino-9,13b-dihydro-1H-dibenz(c,f)imidazo(1,5-a)azepineChemIDplus
(±)-epinastineChemIDplus
Manual XrefsDatabases
D07900KEGG DRUG
DB00751DrugBank
GB2071095Patent
US4313931Patent
EpinastineWikipedia
1027DrugCentral
Registry NumbersSources
Reaxys:3593307Reaxys
CAS:80012-43-7ChemIDplus