CHEBI:4469 - (S)-amphetamine

ChEBI IDCHEBI:4469
ChEBI Name(S)-amphetamine
Stars
ASCII Name(S)-amphetamine
DefinitionA 1-phenylpropan-2-amine that has S configuration.
Last Modified22 February 2017
DownloadsMolfile
FormulaC9H13N
Net Charge0
Average Mass135.210
Monoisotopic Mass135.10480
SMILESC[C@H](N)Cc1ccccc1
InChIInChI=1S/C9H13N/c1-8(10)7-9-5-3-2-4-6-9/h2-6,8H,7,10H2,1H3/t8-/m0/s1
InChIKeyKWTSXDURSIMDCE-QMMMGPOBSA-N
Wikipedia
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
sympathomimetic agent  A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
dopaminergic agent  A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
neurotoxin  A poison that interferes with the functions of the nervous system.
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
adrenergic uptake inhibitor  Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
adrenergic agent  Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.
Applications:
sympathomimetic agent  A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
dopaminergic agent  A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons.
dopamine uptake inhibitor  A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake.
antipsychotic agent  Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
adrenergic uptake inhibitor  Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
antineoplastic agent  A substance that inhibits or prevents the proliferation of neoplasms.
antidepressant  Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions.
immunosuppressive agent  An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
adrenergic agent  Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter.
central nervous system stimulant  Any drug that enhances the activity of the central nervous system.
ChEBI Ontology
Outgoing Relation(s)
(S)-amphetamine (CHEBI:4469) has role adrenergic agent (CHEBI:37962)
(S)-amphetamine (CHEBI:4469) has role adrenergic uptake inhibitor (CHEBI:35640)
(S)-amphetamine (CHEBI:4469) has role antidepressant (CHEBI:35469)
(S)-amphetamine (CHEBI:4469) has role antineoplastic agent (CHEBI:35610)
(S)-amphetamine (CHEBI:4469) has role antipsychotic agent (CHEBI:35476)
(S)-amphetamine (CHEBI:4469) has role dopamine uptake inhibitor (CHEBI:51039)
(S)-amphetamine (CHEBI:4469) has role dopaminergic agent (CHEBI:48560)
(S)-amphetamine (CHEBI:4469) has role immunosuppressive agent (CHEBI:35705)
(S)-amphetamine (CHEBI:4469) has role neurotoxin (CHEBI:50910)
(S)-amphetamine (CHEBI:4469) has role sympathomimetic agent (CHEBI:35524)
(S)-amphetamine (CHEBI:4469) is a 1-phenylpropan-2-amine (CHEBI:132233)
(S)-amphetamine (CHEBI:4469) is a amphetamines (CHEBI:35338)
(S)-amphetamine (CHEBI:4469) is a organic molecular entity (CHEBI:50860)
(S)-amphetamine (CHEBI:4469) is enantiomer of (R)-amphetamine (CHEBI:42724)
Incoming Relation(s)
methamphetamine (CHEBI:6809) has functional parent (S)-amphetamine (CHEBI:4469)
(S)-amphetamine sulfate (CHEBI:51064) has part (S)-amphetamine (CHEBI:4469)
amphetamine (CHEBI:2679) has part (S)-amphetamine (CHEBI:4469)
(R)-amphetamine (CHEBI:42724) is enantiomer of (S)-amphetamine (CHEBI:4469)
IUPAC Name 
(2S)-1-phenylpropan-2-amine
INN  Source
dexanfetaminaWHO MedNet
Synonyms  Source
Amfetamine, (s)-ChEMBL
(+)-amphetamineChEBI
Amphetamine, d-ChEMBL
DexamfetamineChEMBL
dexamphetamineNIST Chemistry WebBook
DexidrineChEMBL
Manual XrefsDatabases
841DrugCentral
C07884KEGG COMPOUND
D03740KEGG DRUG
DB01576DrugBank
DextroamphetamineWikipedia
Registry NumbersSources
Gmelin:1125854Gmelin
Beilstein:2205872Beilstein
CAS:51-64-9ChemIDplus
CAS:51-64-9KEGG COMPOUND
CAS:51-64-9NIST Chemistry WebBook
Citations