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CHEBI:34385 - 4-aminopyridine

Default Structure
ChEBI IDCHEBI:34385
ChEBI Name4-aminopyridine
Stars
DefinitionAn aromatic amine that is pyridine bearing a single amino substituent at position 4. An orphan drug in the US, it is used to improve walking in adults with multiple sclerosis.
Last Modified20 May 2020
DownloadsMolfile
FormulaC5H6N2
Net Charge0
Average Mass94.117
Monoisotopic Mass94.05310
SMILESNc1ccncc1
InChIInChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
InChIKeyNUKYPUAOHBNCPY-UHFFFAOYSA-N
Wikipedia
Roles Classification
Chemical Role:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Role:
potassium channel blocker  An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions.
Applications:
orphan drug  Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease.
avicide  A substance used to destroy bird pests (class Aves).
ChEBI Ontology
Outgoing Relation(s)
4-aminopyridine (CHEBI:34385) has role avicide (CHEBI:33289)
4-aminopyridine (CHEBI:34385) has role orphan drug (CHEBI:71031)
4-aminopyridine (CHEBI:34385) has role potassium channel blocker (CHEBI:50509)
4-aminopyridine (CHEBI:34385) is a aminopyridine (CHEBI:38207)
4-aminopyridine (CHEBI:34385) is a aromatic amine (CHEBI:33860)
Incoming Relation(s)
4-aminonicotinic acid (CHEBI:68577) has functional parent 4-aminopyridine (CHEBI:34385)
4-aminopyridine-3-methanol (CHEBI:149772) has functional parent 4-aminopyridine (CHEBI:34385)
torasemide (CHEBI:9637) has functional parent 4-aminopyridine (CHEBI:34385)
IUPAC Name 
pyridin-4-amine
INNs  Source
fampridinaWHO MedNet
fampridineKEGG DRUG
fampridineWHO MedNet
fampridinumWHO MedNet
Synonyms  Source
4-AminopyridineKEGG COMPOUND
4-APKEGG COMPOUND
4-PyridinamineChemIDplus
4-PyridylamineChemIDplus
AvitrolChemIDplus
DalfampridineKEGG DRUG
Brand Name  Source
AmpyraKEGG DRUG
Manual XrefsDatabases
1348PPDB
4163DrugCentral
4APPDBeChem
C13728KEGG COMPOUND
D04127KEGG DRUG
DalfampridineWikipedia
Registry NumbersSources
Reaxys:105782Reaxys
CAS:504-24-5ChemIDplus
CAS:504-24-5NIST Chemistry WebBook
CAS:504-24-5KEGG COMPOUND
Citations