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CHEBI:34385 - 4-aminopyridine
| Formula | C5H6N2 |
| Net Charge | 0 |
| Average Mass | 94.117 |
| Monoisotopic Mass | 94.05310 |
| SMILES | Nc1ccncc1 |
| InChI | InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7) |
| InChIKey | NUKYPUAOHBNCPY-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Chemical Role: | Bronsted base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). |
| Biological Roles: | potassium channel blocker An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| Applications: | vulnerary A drug used in treating and healing of wounds. avicide A substance used to destroy bird pests (class Aves). orphan drug Any drug that has been developed specifically for treatment of a rare medical condition, the condition itself being known as an orphan disease. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| 4-aminopyridine (CHEBI:34385) has role avicide (CHEBI:33289) |
| 4-aminopyridine (CHEBI:34385) has role immunosuppressive agent (CHEBI:35705) |
| 4-aminopyridine (CHEBI:34385) has role orphan drug (CHEBI:71031) |
| 4-aminopyridine (CHEBI:34385) has role potassium channel blocker (CHEBI:50509) |
| 4-aminopyridine (CHEBI:34385) has role vulnerary (CHEBI:73336) |
| 4-aminopyridine (CHEBI:34385) is a aminopyridine (CHEBI:38207) |
| 4-aminopyridine (CHEBI:34385) is a aromatic amine (CHEBI:33860) |
| Incoming Relation(s) |
| 4-aminonicotinic acid (CHEBI:68577) has functional parent 4-aminopyridine (CHEBI:34385) |
| 4-aminopyridine-3-methanol (CHEBI:149772) has functional parent 4-aminopyridine (CHEBI:34385) |
| torasemide (CHEBI:9637) has functional parent 4-aminopyridine (CHEBI:34385) |
| IUPAC Name |
|---|
| pyridin-4-amine |
| INNs | Source |
|---|---|
| fampridina | WHO MedNet |
| fampridine | KEGG DRUG |
| fampridine | WHO MedNet |
| fampridinum | WHO MedNet |
| Synonyms | Source |
|---|---|
| 4-Aminopyridine | KEGG COMPOUND |
| 4-AP | KEGG COMPOUND |
| 4-Pyridinamine | ChemIDplus |
| 4-Pyridylamine | ChemIDplus |
| Avitrol | ChemIDplus |
| dalfampridine | ChEMBL |
| Brand Names | Source |
|---|---|
| Ampyra | KEGG DRUG |
| Ampyra extended release | ChEMBL |
| Fampridine accord | ChEMBL |
| Citations |
|---|