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CHEBI:28790 - serotonin

ChEBI IDCHEBI:28790
ChEBI Nameserotonin
Stars
DefinitionA primary amino compound that is the 5-hydroxy derivative of tryptamine.
Secondary ChEBI IDsCHEBI:1420, CHEBI:26652, CHEBI:49894
Last Modified14 December 2016
DownloadsMolfile
FormulaC10H12N2O
Net Charge0
Average Mass176.219
Monoisotopic Mass176.09496
SMILESNCCc1cnc2ccc(O)cc12
InChIInChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2
InChIKeyQZAYGJVTTNCVMB-UHFFFAOYSA-N
Wikipedia
Species of MetaboliteComponentSourceComments
Homo sapiens (ncbitaxon:9606) - PubMed (24136337)
Mus musculus (ncbitaxon:10090) - PubMed (19425150) Source: BioModels - MODEL1507180067
Paramuricea clavata (ncbitaxon:317549) - PubMed (21939218) CH2Cl2:MeOH(1:1) extract of lyophilized material
Roles Classification
Chemical Roles:
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Bronsted base  A molecular entity capable of accepting a hydron from a donor (Brønsted acid).
Biological Roles:
mouse metabolite  Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
neurotransmitter  An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
human metabolite  Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
ChEBI Ontology
Outgoing Relation(s)
serotonin (CHEBI:28790) has functional parent tryptamine (CHEBI:16765)
serotonin (CHEBI:28790) has role human metabolite (CHEBI:77746)
serotonin (CHEBI:28790) has role mouse metabolite (CHEBI:75771)
serotonin (CHEBI:28790) has role neurotransmitter (CHEBI:25512)
serotonin (CHEBI:28790) is a hydroxyindoles (CHEBI:84729)
serotonin (CHEBI:28790) is a monoamine molecular messenger (CHEBI:25375)
serotonin (CHEBI:28790) is a phenols (CHEBI:33853)
serotonin (CHEBI:28790) is a primary amino compound (CHEBI:50994)
serotonin (CHEBI:28790) is a tryptamines (CHEBI:27162)
serotonin (CHEBI:28790) is conjugate base of serotonin(1+) (CHEBI:350546)
Incoming Relation(s)
(2E)-N-{2-[5,5'-dihydroxy-3'-(2-{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl}-3-(4-hydroxy-3-methoxyphenyl)prop-2-enimidic acid (CHEBI:184799) has functional parent serotonin (CHEBI:28790)
(2E)-N-{2-[5,5'-dihydroxy-3'-(2-{[(2E)-1-hydroxy-3-(4-hydroxy-3-methoxyphenyl)prop-2-en-1-ylidene]amino}ethyl)-1H,1'H-[4,4'-biindole]-3-yl]ethyl}-3-(4-hydroxyphenyl)prop-2-enimidic acid (CHEBI:185584) has functional parent serotonin (CHEBI:28790)
N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-L-glutamine residue (CHEBI:167174) has functional parent serotonin (CHEBI:28790)
N-acylserotonin (CHEBI:134175) has functional parent serotonin (CHEBI:28790)
N-arachidonoyl-2-oxoserotonin (CHEBI:132256) has functional parent serotonin (CHEBI:28790)
N-methylserotonin (CHEBI:48294) has functional parent serotonin (CHEBI:28790)
N,O-dimethylserotonin (CHEBI:189635) has functional parent serotonin (CHEBI:28790)
1-(5-methoxy-1H-indol-3-yl)-2-propanamine (CHEBI:125422) has functional parent serotonin (CHEBI:28790)
1-[5-(thiophen-2-ylmethoxy)-1H-indol-3-yl]-2-propanamine (CHEBI:91556) has functional parent serotonin (CHEBI:28790)
2-methylserotonin (CHEBI:31085) has functional parent serotonin (CHEBI:28790)
2,2,2-trideuterio-N-[1,1,2,2-tetradeuterio-2-(5-hydroxy-1H-indol-3-yl)ethyl]acetamide (CHEBI:125590) has functional parent serotonin (CHEBI:28790)
3-(2-aminoethyl)-6-methoxy-1H-indol-5-ol 2-amino-3-methyl-4H-imidazol-5-one (CHEBI:125692) has functional parent serotonin (CHEBI:28790)
3-(2-aminoethyl)-7-methoxy-1H-indol-5-ol 2-amino-3-methyl-4H-imidazol-5-one (CHEBI:125691) has functional parent serotonin (CHEBI:28790)
5-Methoxy DL-tryptophan (CHEBI:86571) has functional parent serotonin (CHEBI:28790)
5-Methoxy-DL-tryptophan (CHEBI:194846) has functional parent serotonin (CHEBI:28790)
5-methoxytryptamine (CHEBI:2089) has functional parent serotonin (CHEBI:28790)
5-nonyloxytryptamine (CHEBI:64149) has functional parent serotonin (CHEBI:28790)
Creatinine sulfate mixture with serotonin (CHEBI:166585) has functional parent serotonin (CHEBI:28790)
N6-cis-p-Coumaroylserotonin (CHEBI:175113) has functional parent serotonin (CHEBI:28790)
Serotonin hydrochloride (CHEBI:181195) has functional parent serotonin (CHEBI:28790)
serotonin(1+) (CHEBI:350546) is conjugate acid of serotonin (CHEBI:28790)
IUPAC Name 
3-(2-aminoethyl)-1H-indol-5-ol
Synonyms  Source
3-(2-Aminoethyl)-1H-indol-5-olKEGG COMPOUND
3-(2-Aminoethyl)-1H-indol-5-olKEGG COMPOUND
5-HTIUPHAR
5-HydroxytryptamineKEGG COMPOUND
EnteramineKEGG COMPOUND
SerotoninKEGG COMPOUND
Manual XrefsDatabases
C00001429KNApSAcK
C00780KEGG COMPOUND
HMDB0000259HMDB
LSM-6589LINCS
SerotoninWikipedia
SEROTONINMetaCyc
SROPDBeChem
Registry NumbersSources
Reaxys:143524Reaxys
Gmelin:1861995Gmelin
CAS:50-67-9ChemIDplus
CAS:50-67-9KEGG COMPOUND
Citations