EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:15956 - biotin
| Formula | C10H16N2O3S |
| Net Charge | 0 |
| Average Mass | 244.316 |
| Monoisotopic Mass | 244.08816 |
| SMILES | [H][C@]12CS[C@@H](CCCCC(=O)O)[C@@]1([H])NC(=O)N2 |
| InChI | InChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1 |
| InChIKey | YBJHBAHKTGYVGT-ZKWXMUAHSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Escherichia coli (ncbitaxon:562) | - | PubMed (21988831) | |
| Homo sapiens (ncbitaxon:9606) | |||
| saliva (UBERON:0001836) | Article (Sugimoto et al. (2013) Physiological and environmental parameters associated with mass spectrometry-based salivary metabolomic profiles. ) | ||
| cerebrospinal fluid (UBERON:0001359) | PubMed (10577274) | ||
| - | MetaboLights (MTBLS87) | From MetaboLights | |
| blood (UBERON:0000178) | Article (Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.) | ||
| urine (BTO:0001419) | Article (Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.) | ||
| Mus musculus (ncbitaxon:10090) | - | PubMed (19425150) | Source: BioModels - MODEL1507180067 |
| Roles Classification |
|---|
| Chemical Role: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | coenzyme A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. prosthetic group A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity. Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). fundamental metabolite Any metabolite produced by all living cells. mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). water-soluble vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine. |
| Applications: | anti-asthmatic agent Any compound that has anti-asthmatic effects. immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. anti-anaemic agent A compound which increases either the number of red cells or the amount of haemoglobin in the blood. renoprotective agent Any compound that is able to prevent damage to the kidneys. nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. hypoglycemic agent A drug which lowers the blood glucose level. cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| biotin (CHEBI:15956) has role Escherichia coli metabolite (CHEBI:76971) |
| biotin (CHEBI:15956) has role Saccharomyces cerevisiae metabolite (CHEBI:75772) |
| biotin (CHEBI:15956) has role anti-anaemic agent (CHEBI:75835) |
| biotin (CHEBI:15956) has role anti-asthmatic agent (CHEBI:65023) |
| biotin (CHEBI:15956) has role cardiovascular drug (CHEBI:35554) |
| biotin (CHEBI:15956) has role coenzyme (CHEBI:23354) |
| biotin (CHEBI:15956) has role cofactor (CHEBI:23357) |
| biotin (CHEBI:15956) has role fundamental metabolite (CHEBI:78675) |
| biotin (CHEBI:15956) has role human metabolite (CHEBI:77746) |
| biotin (CHEBI:15956) has role hypoglycemic agent (CHEBI:35526) |
| biotin (CHEBI:15956) has role immunosuppressive agent (CHEBI:35705) |
| biotin (CHEBI:15956) has role mouse metabolite (CHEBI:75771) |
| biotin (CHEBI:15956) has role nutraceutical (CHEBI:50733) |
| biotin (CHEBI:15956) has role prosthetic group (CHEBI:26348) |
| biotin (CHEBI:15956) has role renoprotective agent (CHEBI:231911) |
| biotin (CHEBI:15956) is a biotins (CHEBI:51570) |
| biotin (CHEBI:15956) is a vitamin B7 (CHEBI:176841) |
| biotin (CHEBI:15956) is conjugate acid of biotinate (CHEBI:57586) |
| Incoming Relation(s) |
| biocytin (CHEBI:27870) has functional parent biotin (CHEBI:15956) |
| biotin amide (CHEBI:16615) has functional parent biotin (CHEBI:15956) |
| biotinyl-5'-AMP (CHEBI:3110) has functional parent biotin (CHEBI:15956) |
| biotinyl-CoA (CHEBI:15516) has functional parent biotin (CHEBI:15956) |
| GCB (CHEBI:74858) has functional parent biotin (CHEBI:15956) |
| vitamin B complex (CHEBI:75782) has part biotin (CHEBI:15956) |
| biotinate (CHEBI:57586) is conjugate base of biotin (CHEBI:15956) |
| biotinyl group (CHEBI:22885) is substituent group from biotin (CHEBI:15956) |
| IUPAC Name |
|---|
| 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid |
| INNs | Source |
|---|---|
| biotin | WHO MedNet |
| biotina | WHO MedNet |
| biotine | WHO MedNet |
| biotinum | WHO MedNet |
| Synonyms | Source |
|---|---|
| (3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-valeric acid | HMDB |
| 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid | HMDB |
| BIOTIN | PDBeChem |
| (+)-cis-Hexahydro-2-oxo-1H-thieno[3,4]imidazole-4-valeric acid | HMDB |
| cis-Hexahydro-2-oxo-1H-thieno(3,4)imidazole-4-valeric acid | HMDB |
| cis-Tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid | HMDB |
| Brand Names | Source |
|---|---|
| Biotin 100 | ChEMBL |
| Biotin component of vitaped | ChEMBL |
| Citations |
|---|