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CHEBI:15956 - biotin
| Formula | C10H16N2O3S |
| Net Charge | 0 |
| Average Mass | 244.316 |
| Monoisotopic Mass | 244.08816 |
| SMILES | [H][C@]12CS[C@@H](CCCCC(=O)O)[C@@]1([H])NC(=O)N2 |
| InChI | InChI=1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1 |
| InChIKey | YBJHBAHKTGYVGT-ZKWXMUAHSA-N |
| Wikipedia |
|---|
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Homo sapiens (ncbitaxon:9606) | |||
| cerebrospinal fluid (UBERON:0001359) | PubMed (10577274) | ||
| blood (UBERON:0000178) | Article (Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.) | ||
| saliva (UBERON:0001836) | Article (Sugimoto et al. (2013) Physiological and environmental parameters associated with mass spectrometry-based salivary metabolomic profiles. ) | ||
| urine (BTO:0001419) | Article (Geigy Scientific Tables, 8th Rev edition, pp. 130. Edited by C. Lentner, West Cadwell, N.J.: Medical education Div., Ciba-Geigy Corp. Basel, Switzerland c1981-1992.) | ||
| - | MetaboLights (MTBLS87) | From MetaboLights | |
| Escherichia coli (ncbitaxon:562) | - | PubMed (21988831) | |
| Mus musculus (ncbitaxon:10090) | - | PubMed (19425150) | Source: BioModels - MODEL1507180067 |
| Roles Classification |
|---|
| Chemical Role: | Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). |
| Biological Roles: | mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). coenzyme A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons. cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). prosthetic group A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity. Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). fundamental metabolite Any metabolite produced by all living cells. Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). water-soluble vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine. |
| Applications: | nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| biotin (CHEBI:15956) has role Escherichia coli metabolite (CHEBI:76971) |
| biotin (CHEBI:15956) has role Saccharomyces cerevisiae metabolite (CHEBI:75772) |
| biotin (CHEBI:15956) has role coenzyme (CHEBI:23354) |
| biotin (CHEBI:15956) has role cofactor (CHEBI:23357) |
| biotin (CHEBI:15956) has role fundamental metabolite (CHEBI:78675) |
| biotin (CHEBI:15956) has role human metabolite (CHEBI:77746) |
| biotin (CHEBI:15956) has role mouse metabolite (CHEBI:75771) |
| biotin (CHEBI:15956) has role nutraceutical (CHEBI:50733) |
| biotin (CHEBI:15956) has role prosthetic group (CHEBI:26348) |
| biotin (CHEBI:15956) is a biotins (CHEBI:51570) |
| biotin (CHEBI:15956) is a vitamin B7 (CHEBI:176841) |
| biotin (CHEBI:15956) is conjugate acid of biotinate (CHEBI:57586) |
| Incoming Relation(s) |
| biocytin (CHEBI:27870) has functional parent biotin (CHEBI:15956) |
| biotin amide (CHEBI:16615) has functional parent biotin (CHEBI:15956) |
| biotinyl-5'-AMP (CHEBI:3110) has functional parent biotin (CHEBI:15956) |
| biotinyl-CoA (CHEBI:15516) has functional parent biotin (CHEBI:15956) |
| GCB (CHEBI:74858) has functional parent biotin (CHEBI:15956) |
| vitamin B complex (CHEBI:75782) has part biotin (CHEBI:15956) |
| biotinate (CHEBI:57586) is conjugate base of biotin (CHEBI:15956) |
| biotinyl group (CHEBI:22885) is substituent group from biotin (CHEBI:15956) |
| IUPAC Name |
|---|
| 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid |
| INNs | Source |
|---|---|
| biotin | WHO MedNet |
| biotina | WHO MedNet |
| biotine | WHO MedNet |
| biotinum | WHO MedNet |
| Synonyms | Source |
|---|---|
| D-Biotin | KEGG COMPOUND |
| Vitamin H | KEGG COMPOUND |
| Coenzyme R | KEGG COMPOUND |
| BIOTIN | PDBeChem |
| vitamin B7 | NIST Chemistry WebBook |
| D-(+)-biotin | NIST Chemistry WebBook |
| Citations |
|---|