EMBL-EBI | Chemical Biology | ChEBI
Example searches: iron*, InChI=1S/CH4O/c1-2/h2H,1H3, caffeine | Advanced Search
CHEBI:102248 - EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor
| ChEBI ID | CHEBI:102248 |
| ChEBI Name | EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor |
| Stars | |
| Definition | An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29). |
| Last Modified | 16 January 2024 |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248) is a EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor (CHEBI:76902) |
| Incoming Relation(s) |
| daprodustat (CHEBI:229223) has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248) |
| dimethyloxalylglycine (CHEBI:102218) has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248) |
| roxadustat (CHEBI:132774) has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248) |
| Synonyms | Source |
|---|---|
| EC 1.14.11.29 inhibitors | ChEBI |
| EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitors | ChEBI |
| prolyl 4-hydroxylase inhibitor | ChEBI |
| HIF hydroxylase inhibitors | ChEBI |
| hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitors | ChEBI |
| hypoxia-inducible factor-L-proline, 2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating) inhibitor | ChEBI |