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CHEBI:102218 - dimethyloxalylglycine

ChEBI IDCHEBI:102218
ChEBI Namedimethyloxalylglycine
Stars
DefinitionA glycine derivative that is the diester obtained by formal condensation of the carboxy groups of N-oxalylglycine with two molecules of methanol.
Last Modified7 March 2018
DownloadsMolfile
FormulaC6H9NO5
Net Charge0
Average Mass175.140
Monoisotopic Mass175.04807
SMILESCOC(=O)CNC(=O)C(=O)OC
InChIInChI=1S/C6H9NO5/c1-11-4(8)3-7-5(9)6(10)12-2/h3H2,1-2H3,(H,7,9)
InChIKeyBNJOZDZCRHCODO-UHFFFAOYSA-N
Roles Classification
Biological Role:
EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor  An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of hypoxia-inducible factor-proline dioxygenase (EC 1.14.11.29).
Application:
neuroprotective agent  Any compound that can be used for the treatment of neurodegenerative disorders.
ChEBI Ontology
Outgoing Relation(s)
dimethyloxalylglycine (CHEBI:102218) has functional parent N-oxalylglycine (CHEBI:44482)
dimethyloxalylglycine (CHEBI:102218) has role EC 1.14.11.29 (hypoxia-inducible factor-proline dioxygenase) inhibitor (CHEBI:102248)
dimethyloxalylglycine (CHEBI:102218) has role neuroprotective agent (CHEBI:63726)
dimethyloxalylglycine (CHEBI:102218) is a glycine derivative (CHEBI:24373)
dimethyloxalylglycine (CHEBI:102218) is a methyl ester (CHEBI:25248)
dimethyloxalylglycine (CHEBI:102218) is a secondary carboxamide (CHEBI:140325)
IUPAC Name 
methyl N-[methoxy(oxo)acetyl]glycinate
Synonyms  Source
DMOGChEBI
N-(2-methoxy-2-oxoacetyl)glycine methyl esterChEBI
N-oxalylglycine dimethyl esterChEBI
methyl N-(2-methoxy-2-oxoacetyl)glycinateChEBI
Registry NumbersSources
Reaxys:2096268Reaxys
Citations