UniProt release 2016_07

UniProt release 2016_07 is out now with 65,930,454 proteins!

Headline article

Our article on '(Bacterial) immigration under control' is available on the UniProt website: http://www.uniprot.org/help/2016/07/06/release.

News

Changes to the controlled vocabulary of human diseases

New diseases:

• Advanced sleep phase syndrome, familial, 3
• Alzheimer disease 9
• Behr syndrome
• Bleeding disorder, platelet-type 20
• Charcot-Marie-Tooth disease 2CC
• Coffin-Siris syndrome 1
• Developmental delay with short stature, dysmorphic features, and sparse hair
• Dyskinesia, limb and orofacial, infantile-onset
• Hypotonia, infantile, with psychomotor retardation and characteristic facies 3
• Immunodeficiency-centromeric instability-facial anomalies syndrome 3
• Immunodeficiency-centromeric instability-facial anomalies syndrome 4
• Leukodystrophy, hypomyelinating, 13
• Macular dystrophy, patterned, 2
• Mental retardation, autosomal recessive 52
• Mental retardation, autosomal recessive 53
• Mitochondrial DNA depletion syndrome 14, cardioencephalomyopathic type
• Nephrotic syndrome 12
• Nephrotic syndrome 13
• Osteochondrodysplasia, complex lethal, Symoens-Barnes-Gistelinck type
• Osteofibrous dysplasia
• Robinow syndrome, autosomal dominant 3
• Split-foot malformation with mesoaxial polydactyly
• Striatal degeneration, autosomal dominant 2

Modified diseases:

• Cataract 19 -> Cataract, multiple types 19
• Epsilon-trimethyllysine hydroxylase deficiency -> Autism, X-linked 6
• Klippel-Feil syndrome 4, autosomal recessive, with myopathy and facial dysmorphism -> Klippel-Feil syndrome 4, autosomal recessive, with nemaline myopathy and facial dysmorphism
• Mucolipidosis type IV -> Mucolipidosis 4
• Mental retardation, autosomal dominant 14 -> Coffin-Siris syndrome 2
• Mental retardation, autosomal dominant 15 -> Coffin-Siris syndrome 3
• Mental retardation, autosomal dominant 16 -> Coffin-Siris syndrome 4
• Striatal degeneration autosomal dominant -> Striatal degeneration, autosomal dominant 1
• The autosomal recessive cornea plana 2 -> Cornea plana 2, autosomal recessive

Deleted diseases

• Ciliary dyskinesia, primary, 31
• Jensen syndrome
• Mental retardation, autosomal dominant 12
• Thiopurine S-methyltransferase deficiency