News archive 2020

May

26 May 2020

Distinguishing coronavirus genome mutations from inadvertent errors

EMBL-EBIhttp://virological.org/t/issues-with-sars-cov-2-sequencing-data/473 scientists have performed a large-scale analysis of SARS-CoV-2 genomes, which reveals a need for cautious interpretation of sequencing data to identify mutations within the virus’s genome. Read more
Artist's impression of the research. Credit: Holly Joynes, Rayne Zaayman-Gallant/EMBL; Adobe Stock
18 May 2020

An automated method for cell type discovery

Identifying cell types from single-cell RNA sequencing data is now more efficient than ever. Read more
Artist's interpretation of cell clusters in humans and mice.
18 May 2020

May 2020 releases: Single Cell Expression Atlas and Expression Atlas

The latest releases for the Expression Atlases are now available. We’ve been working hard with all our collaborators to curate and process the latest datasets. This new release contains data from three main projects and highlights 23 new datasets aiding research on COVID-19 disease caused by the novel coronavirus SARS-CoV-2.  All information can be found via the release notes for bulk and single cell Expression Atlases. Read more
Expression Atlas, Single Cell Expression Atlas releases
18 May 2020

Ensembl launches COVID-19 resource

Today, Ensembl has joined the international scientific effort to tackle the COVID-19 pandemic. COVID-19 is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has spread rapidly since emerging in late 2019. Ensembl's SARS-CoV-2 genome browser and related resources at covid-19.ensembl.org are intended to support both basic research and ongoing work to develop treatments, diagnostics and vaccines. Read more
Ensembl logo on bluebackground
5 May 2020

New releases: InterPro 79.0 and InterProScan 5.44-79.0

InterPro version 79.0 and InterProScan 5.44-79.0 are now available! InterPro now features hundreds of new methods integrated from partner databases, and InterProScan draws on over 37 000 entries. Read more
InterPro: protein sequence analysis & classification
1 May 2020

DNA damage and faulty repair jointly cause mutations

Genome sequencing gives new insights into cancer genomics Read more
C elegans microscopy image with DNA superimposed

April

30 Apr 2020

Ensembl 100 has been released!

We are very excited to announce the release of Ensembl 100, along with Ensembl Genomes 47. Time has really flown for us. We moved from our beginnings as a browser with just one genome 20 years ago to an integrated resource for many species and data types in 2020. In this release we continue to scale up, bringing you 29 new genomes and a lot more. Read more
Ensembl logo
22 Apr 2020

Why share data during a pandemic?

To stop the new coronavirus pandemic, scientists all over the world must collaborate and share data Read more
A collage of images showing wet lab, dry lab research and healthcare
18 Apr 2020

EMBL-EBI launches COVID-19 Data Portal

EMBL-EBI and partners launch the COVID-19 Data Portal to help scientists, public health and healthcare professionals tackle the coronavirus pandemic Read more
COVID-19 Data Portal facilitates data sharing about novel coronavirus
16 Apr 2020

Release 143 of ENA's assembled/annotated sequences is now available

Release 143 of assembled/annotated sequences from ENA is now available on the EBI public ftp server at  Read more
6 Apr 2020

Submissions to ENA through all tools and interfaces are in operation and open for all data types

Submissions to ENA through all tools and interfaces are in operation and open for all data types. Due to continuing work arising from the ongoing EMBL-EBI data centre migration programme and the UK COVID-19 lockdown situation, submissions that require the upload of data files across FTP are operating at reduced capacity, but comprehensively, so users may observe slower performance than usual as a result.  Read more

March

31 Mar 2020

ENA data submission service disruption

Due to an unexpected issue resulting from the ongoing EMBL-EBI data centre migration programme, further hampered by the UK COVID-19 lockdown situation, we are unable to offer ENA submissions services at this time. We recommend that you check this page regularly and subscribe to the ENA-announce mailing list (https://listserver.ebi.ac.uk/mailman/listinfo/ena-announce) for updates on service resumption. We apologise for this inconvenience. Read more
26 Mar 2020

EMBL-EBI leads international collaboration to share COVID-19 research data

EMBL-EBI set to launch European COVID-19 Data Platform to help store, share, and analyse research data linked to the COVID-19 pandemic  Read more
Artist's interpretation of COVID-19 data sharing networks around the world
23 Mar 2020

New insights into the regulators that control cell shape

First systematic functional characterisation and systems view of Rho GTPases, the key regulators of cell shape changes Read more
18 Mar 2020

Coronavirus: latest EMBL-EBI updates

In response to the coronavirus outbreak, EMBL-EBI closes its premises on 18 March, but will continue to maintain data services Read more
EMBL-EBI South Building
5 Mar 2020

ENA data submission service (“Webin”) disruptions 11th-27th March

As part of the EMBL-EBI data centre migration programme, ENA data submissions will be disrupted between 11th up to the 27th of March, 2020. The actual service downtime may be slightly shorter than this. We will send an announcement as soon as data submissions are back to normal. All Webin services that upload files using FTP or Aspera to webin.ebi.ac.uk will be unavailable during this time. This includes the following Webin services: Read more
5 Mar 2020

Supporting Equality and Diversity in Science – 2020 Winners

The winners of the Wellcome Genome Campus Best Practice Awards and the future of equality and diversity in science  Read more
Equality and diversity in science Best Practice Award winners 2020
2 Mar 2020

Adaptive evolution of mammalian immunity and metabolism

New study maps positively selected sites across mammalian proteins to identify evolutionary changes in metabolic enzymes  Read more
Clusters of positively selected sites in SERPIN B3

February

27 Feb 2020

Paul Flicek becomes ISCB fellow

The International Society for Computational Biology appoints EMBL-EBI Associate Director as distinguished fellow Read more
Paul Flicek appointed ISCB fellow
26 Feb 2020

Funding to use machine learning in neurodevelopmental disability interventions

Ian Dunham receives funding for UK-Canada machine learning project exploring neurodevelopmental disability Read more
Ian Dunham receives funding for machine learning project
24 Feb 2020

Coronavirus data resources at EMBL-EBI

In response to the current outbreak of coronavirus disease (COVID-19) attributed to the SARS-CoV-2 virus first reported in Wuhan, China, in December 2019, EMBL-EBI is gathering and sharing data resources as they become available.  Researchers can now see a breakdown of relevant data hosted at EMBL-EBI on the Pathogen Portal. This includes sequences of outbreak isolates and records relating to coronavirus biology.  See available data Read more
SARS-CoV-2 protein structure
4 Feb 2020

Cancer mutations occur decades before diagnosis

A large-scale pan-cancer analysis of the evolutionary history of tumours reveals that cancer-causing mutations occur decades before diagnosis  Read more
Artists interpretation of pinpointing the onset of cancer progression
4 Feb 2020

Chromothripsis in human cancer

Newly discovered mutational phenomenon chromothripsis is prevalent across more cancers than previously thought.   Read more
Artists impression of chromothripsis
4 Feb 2020

Characterising RNA alterations in cancer

The largest and most comprehensive catalogue of cancer-specific RNA alterations reveals new insights into the cancer genome  Read more
Artists impression of a gene fusion network.

January

30 Jan 2020

Pinpointing rare disease mutations

New resource that categorises genes essential for supporting life could be used to identify rare disease mutations  Read more
Mouse and human knockout gene data used to identify rare disease genes
17 Jan 2020

The 2019 EMBL Insight Lecture: Ageing and disease

Professor Dame Janet Thornton presents the 2019 EMBL Insight Lecture: Ageing and disease – what is the link? Read more
EMBL Insight Lecture Dame Janet Thornton
16 Jan 2020

Ensembl 99 has been released!

We’re pleased to announce the release of Ensembl 99, and the corresponding release of Ensembl Genomes 46. Along with updates of human gene annotation and variation data, we have a menagerie of new and updated vertebrate species in Ensembl plus a whole set of new plants, mosquitos and flies in Ensembl Genomes. Read more
Ensembl logo
16 Jan 2020

eQTL Catalogue – a new resource for gene expression and splicing QTLs

Open access to uniformly processed gene expression and splicing QTLs from all public studies on humans Read more
eQTL Catalogue