DECIPHER v11.28 Released
The v11.28 DECIPHER release is out now. Find out about the new features and improvements
Updated pLI and LOEUF Scores from gnomAD v4.1
pLI and LOEUF scores across the DECIPHER website have been updated to gnomAD v4.1. These constraint scores measure the amount that a gene is constrained for loss of function variants and can help prioritise variants that are more likely to have a deleterious functional impact. On gene pages, clicking on the name of the score now links to the relevant page on the gnomAD website.
Missense Z Scores added to gene pages
Missense Z scores, based on gnomAD v4.1, are now available on gene pages. These scores measure the amount that a gene is constrained for missense variants.
