Conformations of Biotin in protein structures
Below you will find a JMOL applet
of the superimosed molecules of Biotin. There is one applet for each
PDB HET code that is associated with this cofactor. The structures have been
clustered by their pairwise distance (RMSD) and each cluster has a different colour.
The clustering algorithm is described in reference [KGS].
These applets illustrate the conformational space that the cofactor has when
bound to the protein. The superposition has been performed on the most rigid part
(aromatic ring structures where possible). This information is even more useful
when combined with the solvent accessibility analysis.
If you cannot see the applet(s), you first have to install a Java browser plugin
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Structures for HET code BTN
|
|
| Structure |
Cluster |
Species |
E.C. number |
CATH domain |
Resolution |
| 2f01 |
|
Streptomyces avidinii |
|
|
0.85Å |
| 3ew2 |
|
Rhizobium etli
(strain CFN 42 / ATCC 51251) |
|
|
2.30Å |
| 2rtg |
|
Streptomyces avidinii |
|
|
1.39Å |
| 1n43 |
|
Streptomyces avidinii |
|
|
1.89Å |
| 1swg |
|
Streptomyces avidinii |
|
|
1.80Å |
| 2gh7 |
|
Streptomyces avidinii |
|
|
1.00Å |
| 2avi |
|
Gallus gallus
(Chicken) |
|
|
3.00Å |
| 1y55 |
|
Gallus gallus
(Chicken) |
|
|
1.00Å |
| 1y52 |
|
Gallus gallus
(Chicken) |
|
|
1.70Å |
| 1swt |
|
Streptomyces avidinii |
|
|
2.00Å |
| 1swr |
|
Streptomyces avidinii |
|
|
1.90Å |
| 1swn |
|
Streptomyces avidinii |
|
|
2.20Å |
| 1swk |
|
Streptomyces avidinii |
|
|
2.00Å |
| 1swe |
|
Streptomyces avidinii |
|
|
2.06Å |
| 1swd |
|
Streptomyces avidinii |
|
|
1.90Å |
| 1ndj |
|
Streptomyces avidinii |
|
|
1.81Å |
| 1n9m |
|
Streptomyces avidinii |
|
|
1.60Å |
| 1mk5 |
|
Streptomyces avidinii |
|
|
1.40Å |
| 1luq |
|
Streptomyces avidinii |
|
|
0.96Å |
| 1df8 |
|
Streptomyces avidinii |
|
|
1.51Å |
| 1swp |
|
Streptomyces avidinii |
|
|
2.00Å |
| 2izi |
|
Streptomyces avidinii |
|
|
1.50Å |
| 2izh |
|
Streptomyces avidinii |
|
|
1.36Å |
| 2izg |
|
Streptomyces avidinii |
|
|
1.36Å |
| 2izf |
|
Streptomyces avidinii |
|
|
1.58Å |
| 2c4i |
|
Gallus gallus
(Chicken) |
|
|
1.95Å |
| 2c1q |
|
N/A |
|
|
2.10Å |
| 1wbi |
|
Gallus gallus
(Chicken) |
|
|
1.40Å |
| 2izj |
|
Streptomyces avidinii |
|
|
1.30Å |
| 1avd |
|
Gallus gallus
(Chicken) |
|
|
2.70Å |
| 1bib |
|
Escherichia coli
(strain K12) |
6.3.4.15 |
3.30.930.10 |
2.80Å |
| 1f27 |
|
N/A |
|
|
1.30Å |
| 2ejg |
|
Pyrococcus horikoshii |
|
|
2.71Å |
| 2ejf |
|
Pyrococcus horikoshii |
|
2.40.50.100 |
2.00Å |
| 2fyk |
|
Pyrococcus horikoshii |
|
|
1.60Å |
| 2ej9 |
|
Methanocaldococcus jannaschii
(Methanococcus jannaschii) |
6.3.4.15 |
|
2.00Å |
| 2dxt |
|
Pyrococcus horikoshii |
|
|
1.60Å |
| 2zgw |
|
Pyrococcus horikoshii |
|
|
1.50Å |
| 1hxd |
|
Escherichia coli
(strain K12) |
6.3.4.15 |
3.30.930.10 |
2.40Å |
| 2dto |
|
Pyrococcus horikoshii |
|
|
1.50Å |
| 2dth |
|
Pyrococcus horikoshii |
|
|
1.95Å |
| 1wpy |
|
Pyrococcus horikoshii |
|
|
1.60Å |
| 2zsc |
|
Pleurotus cornucopiae
(Cornucopia mushroom) |
|
2.40.128.30 |
1.30Å |
| 2rte |
|
Streptomyces avidinii |
|
|
1.50Å |
| 1stp |
|
Streptomyces avidinii |
|
|
2.60Å |
| 1nqm |
|
Streptomyces avidinii |
|
|
1.70Å |
| 1mep |
|
Streptomyces avidinii |
|
|
1.65Å |
| 3g8c |
|
Escherichia coli
(strain K12) |
|
3.40.50.20 |
2.00Å |
| 2rtf |
|
Streptomyces avidinii |
|
|
1.47Å |
| 2rtd |
|
Streptomyces avidinii |
|
|
1.65Å |
| 1xny |
|
Streptomyces coelicolor |
|
|
2.20Å |
| 2jgs |
|
Gallus gallus
(Chicken) |
|
|
1.90Å |
|
References
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