Thornton Group Home Page

The goal of our research is to understand more about how biology works at the molecular level, how enzymes perform catalysis, how these molecules recognise one another and their cognate ligands, and how proteins and organisms have evolved to create life. We develop and use novel computational methods to analyse the available data, gathering data, either from the literature or by mining the data resources, to answer specific questions. Much of our research is collaborative, involving either experimentalists or other computational biologists. At present we are particularly active in the following 5 areas:

Elucidating and evolution enzyme function through structural analysis
Deriving principles of protein structure
Functional annotation of genomes, proteins and structures
Functional genomics analysis of ageing
Web tool and resource development

A more detailed discussion of our research interests can be found here.
Until January 2002 the Thornton Group was located at the Department of Biochemistry at University College London.

We would like to encourage laboratories wishing to discuss any collaborations to contact us. For information, comments and/or suggestions please contact us.