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EBIGroups

Groups at the EBI

European Bioinformatics Institute (EBI) is a pioneer of novel and developmental bioinformatics research. We have specialist research and services groups providing an invaluable resource of biological data and utilities to aid the scientific community in the understanding of genomic and proteomic data. The EBI's Director is Professor Janet Thornton and Janet also heads the EBI's Research Programme. The Associate Director, Graham Cameron, heads the Services Programme.


Rolf Apweiler - Joint Team Leader Panda (Protein and Nucleotide Database) Group

Panda Proteins
This part of the Panda group is in charge of data resources related to the protein sequence, domains and families database resources.

Paul Bertone - Group Leader

Bertone Group
This group's research lies in the genomic analysis of developmental pathways, with a particular focus on differentiation and lineage commitment in mammalian embryonic stem cells.

Ewan Birney - Joint Team Leader Panda (Protein and Nucleotide Database) Group

Panda Nucleotides
This part of the Panda group is in charge of the nucleotide sequence databases at the EBI that include ENSEMBL, EMBL-Bank and ASTD.

Alvis Brazma - Team Leader

Microarray Group
This group is using microarray technology to analyse the sequence data from the genome projects to identify which genes are expressed in a particular cell type of an organism.

Cath Brooksbank - Scientific Outreach Officer

Outreach and Training
This team is responsible for communicating the EBI's mission and activities to the scientific community, and for coordinating the EBI's training activities - both for users and for EBI staff.

Graham Cameron - Associate Director

Graham Cameron is the Associate Director of the EBI. He is in charge of overseeing services activities as well as coordinating various EU grants.

Dominic Clark - Industry Programme Manager

Industry Support
The EBI supports Industry through two programmes: the EBI Industry Programme is a well established, subscription-based programme for large companies whereas the SME Support Forum offers support to smaller companies that are not eligible to join the Industry Programme.

Guy Cochrane - Team Leader

European Nucleotide Archive Team
This team provides data repositories and services in the nucleotide sequencing domain, from raw reads, through assembled sequences to submitted functional annotation. Serving both as a public-facing resource and as a key infrastructure to other EBI services, the team's work includes the provision of submission services and data access tools and represents the European arm of the International Nucleotide Sequence Database Collaboration.

Anton Enright - Group Leader Enright Group

Enright Group
This group will focus on a number of problems relating to the prediction of the functions of genes and proteins in living organisms.

Paul Flicek - Team Leader Panda Nucleotides (Vertebrate Genomics Group)

Vertebrate Genomics Team
This part of the Panda Nucleotides Group (The Vertebrate Genomics Team) focuses on functional annotation of the genome including methods for incorporating high-throughput epigenetic data for expanding and understanding the collection of human variation.

Phil Gardner - Technical Coordinator

BioSapiens  FELICS

Nick Goldman - Group Leader

Goldman Group
This group is developing methods for the analysis of DNA and amino acid sequences to study evolution.

Mark Green - Head of EBI Administration

Administration
This group is in charge of the administrative side of the EBI.

Midori Harris - GO Editor

GO
The GO Editorial Office at EBI coordinates the development and maintenance of the GO vocabularies, and contributes to several other GO project efforts, including documentation, web presence, software testing, and user support.

Henning Hermjakob - Team Leader

Proteomics Services Team
The team provides databases and tools for the deposition, distribution and analysis of proteomics and proteomics-related data.

Wolfgang Huber - Group Leader

Huber Group
The group's research focuses on the following:
Gene transcription and protein-DNA binding analysis with DNA microarrays, Statistical Computing and High throughput cellular assays and genetic interaction screens.

Sarah Hunter - Team Leader

InterPro Team
This team is responsible for the development and maintenance of the InterPro, Gene Ontology Annotation (GOA) and CluSTr projects. InterPro is an integrated documentation resource for protein families, domains and functional sites, and is used for small and large-scale functional classification of proteins.

Petteri Jokinen - Technical Team Leader

Systems Group (internal access)
This group is is in charge of the maintenance and the development of a state-of-art computing infrastructure on which all EBI operations are run. [Annual Report]

Paul Kersey - Team Leader

Ensembl Genomes Team
The main focus of the team is Ensembl Genomes, the use of the Ensembl software platform for genome analysis and visualisation (which was originally developed for vertebrate genomes) to cover important species from all domains of life. The team maintains five portals (Ensembl Bacteria, Ensembl Protists, Ensembl Fungi, Ensembl Plants and Ensembl Metazoa), and are partners in the VectorBase project, annotating the genomes of invertebrate vectors of human pathogens.

Gerard Kleywegt - Head of PDBe

Protein Databank in Europe (PDBe) Group
This group aims to improve the consistency and quality of the world archive of data on macromolecular structures by integrating current database and informatics technologies with a solid core of expertise in structural biology.

Nicolas Le Novère - Group Leader

Computational Neurobiology Group
The interests of the group Computational Neurobiology revolve around signal transduction in neurons, ranging from the molecular structure of membrane proteins involved in neurotransmission to modelling signalling pathways. A strong focus is the molecular and cellular basis of neuroadaptation in neurons of the basal ganglia. We also provide services that facilitate our research, including database production and software development.

Rodrigo Lopez - Team Leader

External Services Group
This group provides front-end and backbone web services to the user community and is in charge of the main query systems as well as core bioinformatic applications.

Nick Luscombe - Group Leader

Luscombe Group
The Luscombe Group's research focuses on the genomic analysis of regulatory systems.

Johanna McEntyre - Team Leader

Literature Services
Johanna McEntyre is the head of Literature Services.

Kirsten Nyberg - Grants Coordinator

BioSapiens  EMBRACE

John Overington - Team Leader

ChEMBL Team
The ChEMBL team's research focuses on mapping the interactions and functional effects of small molecules binding to their macromolecular targets.

Dietrich Rebholz-Schuhmann - Group Leader

Rebholz Group
The group works on extraction of facts from scientific literature.  This requires know-how in IT, computational linguistics, machine learning, bioinformatics and in biomedicine.  We match facts from text to data in biomedical databases for new findings, and we provide efficient support/services/tools to biologists to make information easily available.  Step by step we achieve to deal with facts from text instead of 'eyeballing' through a set of papers.

Peter Rice - Team Leader

Rice Group
This group is investigating & advising on the e-Science & Grid technology requirements of the EMBL-EBI, through application development plus participation in standards development.

Ugis Sarkans - Technical Team Leader

Technical Team Leader
Ugis Sarkans is in charge of the database development coordination. [Annual Report]

Christoph Steinbeck - Team Leader Chemoinformatics and Metabolism

Steinbeck Team
The Steinbeck team's research in molecular informatics focuses on the understanding of the small-molecule metabolism of living organism, including methods for computer-assisted structure elucidation of biological metabolites and simulations of metabolic pathways.

Janet Thornton - EBI Director

Thornton Group
This group has a wide range of research interests. Using biomolecular structures they are obtaining an understanding of enzyme active sites, protein-protein interactions, protein-ligand interactions, protein-DNA interactions and structure and modelling .

Weimin Zhu - Group Leader

Database Research and Development Group
The Database Research and Development Group Conduct research and development on the database-related challenges. Biomolecular databases are becoming increasingly large, complex and interconnected. This increase of data scale, complexity and the need of interoperability means that there are many fundamental challenges in the database development, deployment and distribution. The group will be leading the EBI's research into database technologies, looking both at solutions from other fields with similar datasets and examining new, cutting edge technologies from database research.



































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