| Enzyme name |
E.C. number |
Enzyme mechanism |
CATH domain |
3D structure |
Species information |
Reference |
| UDP-N-acetylmuramate dehydrogenase |
1.1.1.158 |
|
1.10.1060.10 1.10.45.10 see all
|
1hsk (PDBsum) 1mbb (PDBsum) see all
|
species |
[IntEnz] |
| L-lactate dehydrogenase (cytochrome) |
1.1.2.3 |
M0102 |
|
2oz0 (PDBsum) 1fcb (PDBsum) see all
|
species |
[IntEnz] |
| D-lactate dehydrogenase (cytochrome) |
1.1.2.4 |
|
|
|
species |
[IntEnz] |
| Pyranose oxidase |
1.1.3.10 |
|
|
1tt0 (PDBsum) 1tzl (PDBsum) see all
|
species |
[IntEnz] |
| Pyridoxine 4-oxidase |
1.1.3.12 |
|
|
|
species |
[IntEnz] |
| Alcohol oxidase |
1.1.3.13 |
|
|
|
species |
[IntEnz] |
| (S)-2-hydroxy-acid oxidase |
1.1.3.15 |
|
|
2rdw (PDBsum) 1al7 (PDBsum) see all
|
species |
[IntEnz] |
| Choline oxidase |
1.1.3.17 |
|
|
2jbv
(PDBsum) 3nne
(PDBsum) |
species |
[IntEnz] |
| 4-hydroxymandelate oxidase |
1.1.3.19 |
|
|
|
|
[IntEnz] |
| Glycerol-3-phosphate oxidase |
1.1.3.21 |
|
|
2rgh
(PDBsum) 2rgo
(PDBsum) |
species |
[IntEnz] |
| Thiamine oxidase |
1.1.3.23 |
|
|
|
|
[IntEnz] |
| Malate oxidase |
1.1.3.3 |
|
|
|
|
[IntEnz] |
| D-arabinono-1,4-lactone oxidase |
1.1.3.37 |
|
|
|
species |
[IntEnz] |
| Vanillyl-alcohol oxidase |
1.1.3.38 |
M0103 |
1.10.1060.10 1.10.45.10 see all
|
1ahv (PDBsum) 1ahz (PDBsum) see all
|
species |
[MACiE] |
| Nucleoside oxidase (H(2)O(2)-forming) |
1.1.3.39 |
|
|
|
|
[IntEnz] |
| Glucose oxidase |
1.1.3.4 |
|
1.10.1060.10 1.10.45.10 see all
|
1cf3 (PDBsum) 1gal (PDBsum) see all
|
species |
[IntEnz] |
| Alditol oxidase |
1.1.3.41 |
|
|
2vfr (PDBsum) 2vfs (PDBsum) see all
|
species |
[IntEnz] |
| Cholesterol oxidase |
1.1.3.6 |
|
1.10.1060.10 1.10.45.10 see all
|
1b4v (PDBsum) 1b8s (PDBsum) see all
|
species |
[IntEnz] |
| L-gulonolactone oxidase |
1.1.3.8 |
|
|
|
species |
[IntEnz] |
| Malate dehydrogenase (quinone) |
1.1.5.4 |
|
|
|
|
[IntEnz] |
| Glucose dehydrogenase (acceptor) |
1.1.99.10 |
|
|
|
species |
[IntEnz] |
| Glucoside 3-dehydrogenase |
1.1.99.13 |
|
|
|
|
[IntEnz] |
| Malate dehydrogenase (acceptor) |
1.1.99.16 |
|
|
|
species |
[IntEnz] |
| Cellobiose dehydrogenase (acceptor) |
1.1.99.18 |
|
|
1pl3 (PDBsum) 1d7b (PDBsum) see all
|
species |
[IntEnz] |
| 2-hydroxyglutarate dehydrogenase |
1.1.99.2 |
|
|
|
species |
[IntEnz] |
| D-sorbitol dehydrogenase (acceptor) |
1.1.99.21 |
|
|
|
|
[IntEnz] |
| (R)-pantolactone dehydrogenase (flavin) |
1.1.99.27 |
|
|
|
|
[IntEnz] |
| Pyranose dehydrogenase (acceptor) |
1.1.99.29 |
|
|
|
|
[IntEnz] |
| Gluconate 2-dehydrogenase (acceptor) |
1.1.99.3 |
|
|
|
species |
[IntEnz] |
| Dehydrogluconate dehydrogenase |
1.1.99.4 |
|
|
|
|
[KEGG] |
| D-2-hydroxy-acid dehydrogenase |
1.1.99.6 |
|
|
|
|
[IntEnz] |
| Pyridoxine 5-dehydrogenase |
1.1.99.9 |
|
|
|
|
[IntEnz] |
| o-aminophenol oxidase |
1.10.3.4 |
|
|
|
|
[KEGG] |
| Ribosyldihydronicotinamide dehydrogenase (quinone) |
1.10.99.2 |
|
|
1qr2 (PDBsum) 1sg0 (PDBsum) see all
|
species |
[IntEnz] |
| NADH peroxidase |
1.11.1.1 |
|
1.10.1060.10 1.10.45.10 see all
|
1f8w (PDBsum) 1joa (PDBsum) see all
|
species |
[IntEnz] |
| Hydrogen dehydrogenase |
1.12.1.2 |
|
|
|
species |
[IntEnz] |
| Coenzyme F420 hydrogenase |
1.12.98.1 |
|
|
|
species |
[IntEnz] |
| 2-nitropropane dioxygenase |
1.13.11.32 |
|
|
|
species |
[IntEnz] |
| Arginine 2-monooxygenase |
1.13.12.1 |
|
|
|
|
[KEGG] |
| Nitronate monooxygenase |
1.13.12.16 |
|
|
2gjl
(PDBsum) 2gjn
(PDBsum) |
|
[IntEnz] |
| Lysine 2-monooxygenase |
1.13.12.2 |
|
|
|
|
[IntEnz] |
| Lactate 2-monooxygenase |
1.13.12.4 |
|
|
|
species |
[IntEnz] |
| Benzoate 1,2-dioxygenase |
1.14.12.10 |
|
|
3e99
(PDBsum) |
species |
[KEGG] |
| Naphthalene 1,2-dioxygenase |
1.14.12.12 |
M0130 |
|
2hmo
(PDBsum) |
species |
[MACiE] |
| Nitric oxide dioxygenase |
1.14.12.17 |
|
1.10.1060.10 1.10.45.10 see all
|
1cqx (PDBsum) 1gvh (PDBsum) see all
|
species |
[IntEnz] |
| Benzoyl-CoA 2,3-dioxygenase |
1.14.12.21 |
|
|
|
|
[IntEnz] |
| Benzene 1,2-dioxygenase |
1.14.12.3 |
|
|
3eqq
(PDBsum) |
species |
[IntEnz] |
| 3-hydroxy-2-methylpyridinecarboxylate dioxygenase |
1.14.12.4 |
|
|
|
|
[IntEnz] |
| 5-pyridoxate dioxygenase |
1.14.12.5 |
|
|
|
|
[KEGG] |
| Phthalate 4,5-dioxygenase |
1.14.12.7 |
|
|
|
species |
[IntEnz] |
| 4-sulfobenzoate 3,4-dioxygenase |
1.14.12.8 |
|
|
|
|
[IntEnz] |
| Salicylate 1-monooxygenase |
1.14.13.1 |
|
|
|
species |
[IntEnz] |
| 2,6-dihydroxypyridine 3-monooxygenase |
1.14.13.10 |
|
|
|
|
[KEGG] |
| Monocyclic monoterpene ketone monooxygenase |
1.14.13.105 |
|
|
|
species |
[IntEnz] |
| Limonene 1,2-monooxygenase |
1.14.13.107 |
|
|
|
species |
[IntEnz] |
| 6-hydroxynicotinate 3-monooxygenase |
1.14.13.114 |
|
|
|
|
[IntEnz] |
| 4-hydroxyphenylacetate 1-monooxygenase |
1.14.13.18 |
|
|
|
|
[IntEnz] |
| Taxifolin 8-monooxygenase |
1.14.13.19 |
|
|
|
|
[KEGG] |
| 4-hydroxybenzoate 3-monooxygenase |
1.14.13.2 |
M0131 |
1.10.1060.10 1.10.45.10 see all
|
1bf3 (PDBsum) 1bgj (PDBsum) see all
|
species |
[MACiE] |
| 2,4-dichlorophenol 6-monooxygenase |
1.14.13.20 |
|
|
|
species |
[IntEnz] |
| Cyclohexanone monooxygenase |
1.14.13.22 |
|
|
|
species |
[IntEnz] |
| 3-hydroxybenzoate 4-monooxygenase |
1.14.13.23 |
|
|
|
|
[IntEnz] |
| 3-hydroxybenzoate 6-monooxygenase |
1.14.13.24 |
|
|
|
|
[IntEnz] |
| 4-aminobenzoate 1-monooxygenase |
1.14.13.27 |
|
|
|
|
[IntEnz] |
| 4-nitrophenol 2-monooxygenase |
1.14.13.29 |
|
|
|
|
[IntEnz] |
| 4-hydroxyphenylacetate 3-monooxygenase |
1.14.13.3 |
|
|
3cb0
(PDBsum) |
|
[IntEnz] |
| Albendazole monooxygenase |
1.14.13.32 |
|
|
2v0m
(PDBsum) |
species |
[IntEnz] |
| 4-hydroxybenzoate 3-monooxygenase (NAD(P)H) |
1.14.13.33 |
|
|
|
|
[IntEnz] |
| Melilotate 3-monooxygenase |
1.14.13.4 |
|
|
|
|
[IntEnz] |
| Anthraniloyl-CoA monooxygenase |
1.14.13.40 |
|
|
|
|
[IntEnz] |
| Imidazoleacetate 4-monooxygenase |
1.14.13.5 |
|
|
|
|
[IntEnz] |
| Pentachlorophenol monooxygenase |
1.14.13.50 |
|
|
|
species |
[IntEnz] |
| Ketosteroid monooxygenase |
1.14.13.54 |
|
|
|
|
[IntEnz] |
| Benzoyl-CoA 3-monooxygenase |
1.14.13.58 |
|
|
|
|
[IntEnz] |
| L-lysine 6-monooxygenase (NADPH) |
1.14.13.59 |
|
|
|
species |
[IntEnz] |
| Orcinol 2-monooxygenase |
1.14.13.6 |
|
|
|
|
[IntEnz] |
| 3-hydroxyphenylacetate 6-hydroxylase |
1.14.13.63 |
|
|
|
|
[IntEnz] |
| 4-hydroxybenzoate 1-hydroxylase |
1.14.13.64 |
|
|
|
|
[IntEnz] |
| Phenol 2-monooxygenase |
1.14.13.7 |
|
1.10.1060.10 1.10.45.10 see all
|
1foh
(PDBsum) 1pn0
(PDBsum) |
species |
[IntEnz] |
| Flavin-containing monooxygenase |
1.14.13.8 |
|
|
|
species |
[IntEnz] |
| 4-hydroxyacetophenone monooxygenase |
1.14.13.84 |
|
|
|
species |
[IntEnz] |
| Kynurenine 3-monooxygenase |
1.14.13.9 |
|
|
|
species |
[IntEnz] |
| Zeaxanthin epoxidase |
1.14.13.90 |
|
|
|
species |
[IntEnz] |
| Phenylacetone monooxygenase |
1.14.13.92 |
|
|
1w4x
(PDBsum) |
species |
[IntEnz] |
| Alkanal monooxygenase (FMN-linked) |
1.14.14.3 |
M0132 |
|
1xkj
(PDBsum) 3fgc
(PDBsum) |
species |
[IntEnz] |
| Alkanesulfonate monooxygenase |
1.14.14.5 |
|
|
1nqk
(PDBsum) |
species |
[IntEnz] |
| Methanesulfonate monooxygenase |
1.14.14.6 |
|
|
|
|
[IntEnz] |
| Tryptophan 7-halogenase |
1.14.14.7 |
|
|
|
|
[IntEnz] |
| Lathosterol oxidase |
1.14.21.6 |
|
|
|
species |
[KEGG] |
| Latia-luciferin monooxygenase (demethylating) |
1.14.99.21 |
|
|
|
|
[KEGG] |
| Steroid 9-alpha-monooxygenase |
1.14.99.24 |
|
|
|
|
[IntEnz] |
| Monoprenyl isoflavone epoxidase |
1.14.99.34 |
|
|
|
|
[IntEnz] |
| Squalene monooxygenase |
1.14.99.7 |
|
|
|
species |
[IntEnz] |
| Aquacobalamin reductase |
1.16.1.3 |
|
|
1qfj
(PDBsum) |
species |
[KEGG] |
| Cob(II)alamin reductase |
1.16.1.4 |
|
|
|
|
[KEGG] |
| Aquacobalamin reductase (NADPH) |
1.16.1.5 |
|
|
|
species |
[KEGG] |
| Cyanocobalamin reductase (cyanide-eliminating) |
1.16.1.6 |
|
|
|
|
[KEGG] |
| Ferric-chelate reductase |
1.16.1.7 |
|
|
|
species |
[IntEnz] |
| [Methionine synthase] reductase |
1.16.1.8 |
|
|
2qtl
(PDBsum) 2qtz
(PDBsum) |
species |
[IntEnz] |
| Cob(II)yrinic acid a,c-diamide reductase |
1.16.8.1 |
|
|
|
species |
[IntEnz] |
| Xanthine dehydrogenase |
1.17.1.4 |
M0139 |
|
3eub
(PDBsum) |
species |
[MACiE] |
| Nicotinate dehydrogenase |
1.17.1.5 |
|
|
3hrd
(PDBsum) |
|
[KEGG] |
| Xanthine oxidase |
1.17.3.2 |
|
|
3eub
(PDBsum) |
species |
[IntEnz] |
| 6-hydroxynicotinate dehydrogenase |
1.17.3.3 |
|
|
|
|
[IntEnz] |
| 4-cresol dehydrogenase (hydroxylating) |
1.17.99.1 |
M0141 |
1.10.1060.10 1.10.45.10 see all
|
1dii (PDBsum) 1diq (PDBsum) see all
|
species |
[MACiE] |
| Bile-acid 7-alpha-dehydroxylase |
1.17.99.5 |
|
|
|
species |
[IntEnz] |
| Rubredoxin--NAD(+) reductase |
1.18.1.1 |
|
|
2v3a (PDBsum) 2v3b (PDBsum) see all
|
species |
[IntEnz] |
| Ferredoxin--NADP(+) reductase |
1.18.1.2 |
M0142 |
1.10.1060.10 1.10.45.10 see all
|
1a8p (PDBsum) 1b2r (PDBsum) see all
|
species |
[MACiE] |
| Rubredoxin--NAD(P)(+) reductase |
1.18.1.4 |
|
|
|
|
[IntEnz] |
| Retinal dehydrogenase |
1.2.1.36 |
|
|
1bxs
(PDBsum) 1bi9
(PDBsum) |
species |
[IntEnz] |
| Phenylglyoxylate dehydrogenase (acylating) |
1.2.1.58 |
|
|
|
|
[IntEnz] |
| Pyruvate dehydrogenase (cytochrome) |
1.2.2.2 |
M0275 |
|
3ey9
(PDBsum) 3eya
(PDBsum) |
species |
[KEGG] |
| Carbon-monoxide dehydrogenase (cytochrome b-561) |
1.2.2.4 |
|
|
|
|
[IntEnz] |
| Aldehyde oxidase |
1.2.3.1 |
M0105 |
|
1hlr
(PDBsum) |
species |
[IntEnz] |
| Pyruvate oxidase |
1.2.3.3 |
M0274 |
|
1pow (PDBsum) 1pox (PDBsum) see all
|
species |
[IntEnz] |
| Oxalate oxidase |
1.2.3.4 |
|
|
2ete
(PDBsum) |
species |
[KEGG] |
| Pyruvate oxidase (CoA-acetylating) |
1.2.3.6 |
|
|
|
|
[IntEnz] |
| Indole-3-acetaldehyde oxidase |
1.2.3.7 |
|
|
|
|
[IntEnz] |
| Pyruvate dehydrogenase (quinone) |
1.2.5.1 |
|
|
3ey9
(PDBsum) 3eya
(PDBsum) |
|
[IntEnz] |
| Carbon-monoxide dehydrogenase (acceptor) |
1.2.99.2 |
M0107 |
1.10.1060.10 1.10.45.10 see all
|
1ffu (PDBsum) 1ffv (PDBsum) see all
|
species |
[MACiE] |
| Reticuline oxidase |
1.21.3.3 |
|
|
3d2d (PDBsum) 3d2h (PDBsum) see all
|
species |
[IntEnz] |
| Beta-cyclopiazonate dehydrogenase |
1.21.99.1 |
|
|
|
|
[IntEnz] |
| Iodotyrosine deiodinase |
1.22.1.1 |
|
|
3gb5 (PDBsum) 3gfd (PDBsum) see all
|
|
[IntEnz] |
| Orotate reductase (NADH) |
1.3.1.14 |
|
1.10.1060.10 1.10.45.10 see all
|
1ep1 (PDBsum) 1ep2 (PDBsum) see all
|
|
[IntEnz] |
| Orotate reductase (NADPH) |
1.3.1.15 |
|
|
|
|
[KEGG] |
| 2-enoate reductase |
1.3.1.31 |
|
|
|
species |
[IntEnz] |
| 2,4-dienoyl-CoA reductase (NADPH) |
1.3.1.34 |
M0108 |
|
1ps9 (PDBsum) 1w8d (PDBsum) see all
|
species |
[MACiE] |
| 2-methyl-branched-chain-enoyl-CoA reductase |
1.3.1.52 |
|
|
|
|
[IntEnz] |
| Dihydroorotate oxidase |
1.3.3.1 |
M0109 |
2.10.240.10 3.20.20.70 |
2prm (PDBsum) 3i6r (PDBsum) see all
|
species |
[IntEnz] |
| L-galactonolactone oxidase |
1.3.3.12 |
|
|
|
|
[IntEnz] |
| Protoporphyrinogen oxidase |
1.3.3.4 |
|
3.90.660.20 |
1sez (PDBsum) 2ivd (PDBsum) see all
|
species |
[IntEnz] |
| Acyl-CoA oxidase |
1.3.3.6 |
|
1.10.1060.10 1.10.45.10 see all
|
1is2 (PDBsum) 1w07 (PDBsum) see all
|
species |
[IntEnz] |
| Dihydrouracil oxidase |
1.3.3.7 |
|
|
|
|
[IntEnz] |
| Succinate dehydrogenase (ubiquinone) |
1.3.5.1 |
M0294 |
|
1yq3 (PDBsum) 1yq4 (PDBsum) see all
|
species |
[IntEnz] |
| succinate dehydrogenase |
1.3.99.1 |
M0020 |
1.10.1060.10 1.10.45.10 see all
|
1d4c (PDBsum) 1d4d (PDBsum) see all
|
species |
[MACiE] |
| Isovaleryl-CoA dehydrogenase |
1.3.99.10 |
M0068 |
1.10.1060.10 1.10.45.10 see all
|
1ivh
(PDBsum) |
species |
[MACiE] |
| 2-methylacyl-CoA dehydrogenase |
1.3.99.12 |
|
|
|
|
[IntEnz] |
| Long-chain-acyl-CoA dehydrogenase |
1.3.99.13 |
|
|
|
species |
[IntEnz] |
| Quinoline 2-oxidoreductase |
1.3.99.17 |
|
|
|
species |
[IntEnz] |
| Butyryl-CoA dehydrogenase |
1.3.99.2 |
|
1.10.1060.10 1.10.45.10 see all
|
1buc (PDBsum) 1jqi (PDBsum) see all
|
species |
[IntEnz] |
| (R)-benzylsuccinyl-CoA dehydrogenase |
1.3.99.21 |
|
|
|
species |
[IntEnz] |
| 2-amino-4-deoxychorismate dehydrogenase |
1.3.99.24 |
|
|
|
|
[IntEnz] |
| Acyl-CoA dehydrogenase |
1.3.99.3 |
|
1.10.1060.10 1.10.45.10 see all
|
1egc (PDBsum) 1egd (PDBsum) see all
|
species |
[IntEnz] |
| Glutaryl-CoA dehydrogenase |
1.3.99.7 |
|
|
1siq (PDBsum) 1sir (PDBsum) see all
|
species |
[IntEnz] |
| Glutamate synthase (NADPH) |
1.4.1.13 |
M0304 |
|
2vdc
(PDBsum) 1ea0
(PDBsum) |
species |
[IntEnz] |
| Glutamate synthase (NADH) |
1.4.1.14 |
|
|
|
species |
[IntEnz] |
| D-aspartate oxidase |
1.4.3.1 |
|
|
|
species |
[IntEnz] |
| Putrescine oxidase |
1.4.3.10 |
|
|
|
species |
[IntEnz] |
| L-glutamate oxidase |
1.4.3.11 |
|
|
|
|
[IntEnz] |
| Cyclohexylamine oxidase |
1.4.3.12 |
|
|
|
|
[IntEnz] |
| L-lysine oxidase |
1.4.3.14 |
|
|
|
|
[IntEnz] |
| D-glutamate(D-aspartate) oxidase |
1.4.3.15 |
|
|
|
|
[IntEnz] |
| L-aspartate oxidase |
1.4.3.16 |
|
1.10.1060.10 1.10.45.10 see all
|
1knp (PDBsum) 1knr (PDBsum) see all
|
species |
[IntEnz] |
| Glycine oxidase |
1.4.3.19 |
|
1.10.1060.10 1.10.45.10 see all
|
1ng3 (PDBsum) 1ng4 (PDBsum) see all
|
species |
[IntEnz] |
| L-amino-acid oxidase |
1.4.3.2 |
|
1.10.1060.10 1.10.45.10 see all
|
1f8r (PDBsum) 1f8s (PDBsum) see all
|
species |
[IntEnz] |
| 7-chloro-L-tryptophan oxidase |
1.4.3.23 |
|
|
|
|
[IntEnz] |
| D-amino-acid oxidase |
1.4.3.3 |
M0110 |
1.10.1060.10 1.10.45.10 see all
|
1aa8 (PDBsum) 1an9 (PDBsum) see all
|
species |
[MACiE] |
| Monoamine oxidase |
1.4.3.4 |
|
1.10.1060.10 1.10.45.10 see all
|
1gos (PDBsum) 1h8q (PDBsum) see all
|
species |
[IntEnz] |
| Pyridoxal 5'-phosphate synthase |
1.4.3.5 |
|
|
2a2j (PDBsum) 3hy8 (PDBsum) see all
|
species |
[IntEnz] |
| D-amino acid dehydrogenase (quinone) |
1.4.5.1 |
|
|
|
|
[IntEnz] |
| Glutamate synthase (ferredoxin) |
1.4.7.1 |
M0111 |
3.60.20.10 |
1ofe (PDBsum) 1llw (PDBsum) see all
|
species |
[KEGG] |
| D-amino-acid dehydrogenase |
1.4.99.1 |
|
|
|
species |
[IntEnz] |
| Glycine dehydrogenase (cyanide-forming) |
1.4.99.5 |
|
|
|
|
[IntEnz] |
| Methylenetetrahydrofolate reductase (NAD(P)H) |
1.5.1.20 |
M0120 |
1.10.1060.10 1.10.45.10 see all
|
1b5t (PDBsum) 1v93 (PDBsum) see all
|
species |
[MACiE] |
| FMN reductase |
1.5.1.29 |
|
|
1t0i (PDBsum) 1zch (PDBsum) see all
|
species |
[IntEnz] |
| Sarcosine oxidase |
1.5.3.1 |
M0113 |
1.10.1060.10 1.10.45.10 see all
|
1b3m (PDBsum) 1el5 (PDBsum) see all
|
species |
[MACiE] |
| Dimethylglycine oxidase |
1.5.3.10 |
|
|
3gsi
(PDBsum) |
|
[IntEnz] |
| Polyamine oxidase |
1.5.3.11 |
|
3.90.660.10 |
3cnt
(PDBsum) |
species |
[IntEnz] |
| N(1)-acetylpolyamine oxidase |
1.5.3.13 |
|
|
|
|
[IntEnz] |
| Polyamine oxidase (propane-1,3-diamine-forming) |
1.5.3.14 |
|
|
|
|
[IntEnz] |
| N(8)-acetylspermidine oxidase (propane-1,3-diamine-forming) |
1.5.3.15 |
|
|
|
|
[IntEnz] |
| Spermine oxidase |
1.5.3.16 |
|
|
|
|
[IntEnz] |
| Non-specific polyamine oxidase |
1.5.3.17 |
|
|
1rsg (PDBsum) 1xpq (PDBsum) see all
|
|
[IntEnz] |
| N-methyl-L-amino-acid oxidase |
1.5.3.2 |
|
|
|
|
[KEGG] |
| (S)-6-hydroxynicotine oxidase |
1.5.3.5 |
|
|
|
|
[IntEnz] |
| (R)-6-hydroxynicotine oxidase |
1.5.3.6 |
|
|
|
species |
[IntEnz] |
| Electron-transferring-flavoprotein dehydrogenase |
1.5.5.1 |
M0281 |
|
2gmh
(PDBsum) 2gmj
(PDBsum) |
species |
[IntEnz] |
| Dimethylamine dehydrogenase |
1.5.8.1 |
|
|
|
species |
[IntEnz] |
| Trimethylamine dehydrogenase |
1.5.8.2 |
M0114 |
|
2tmd (PDBsum) 1djn (PDBsum) see all
|
species |
[IntEnz] |
| Sarcosine dehydrogenase |
1.5.99.1 |
|
|
|
species |
[IntEnz] |
| Cytokinin dehydrogenase |
1.5.99.12 |
M0115 |
|
1w1o (PDBsum) 1w1q (PDBsum) see all
|
species |
[IntEnz] |
| D-proline dehydrogenase |
1.5.99.13 |
|
|
|
|
[IntEnz] |
| Dimethylglycine dehydrogenase |
1.5.99.2 |
|
|
|
species |
[IntEnz] |
| Nicotine dehydrogenase |
1.5.99.4 |
|
|
|
|
[IntEnz] |
| Spermidine dehydrogenase |
1.5.99.6 |
|
|
|
|
[IntEnz] |
| Proline dehydrogenase |
1.5.99.8 |
|
|
3e2s
(PDBsum) |
species |
[IntEnz] |
| NAD(P)(+) transhydrogenase (B-specific) |
1.6.1.1 |
|
|
|
species |
[IntEnz] |
| Cytochrome-b5 reductase |
1.6.2.2 |
|
1.10.1060.10 1.10.45.10 see all
|
1i7p (PDBsum) 1ib0 (PDBsum) see all
|
species |
[IntEnz] |
| NADPH--hemoprotein reductase |
1.6.2.4 |
M0117 |
1.10.1060.10 1.10.45.10 see all
|
1amo (PDBsum) 1j9z (PDBsum) see all
|
species |
[MACiE] |
| NADPH--cytochrome-c2 reductase |
1.6.2.5 |
|
|
|
|
[IntEnz] |
| NAD(P)H oxidase |
1.6.3.1 |
|
|
|
species |
[IntEnz] |
| NAD(P)H dehydrogenase (quinone) |
1.6.5.2 |
M0003 |
1.10.1060.10 1.10.45.10 see all
|
1d4a (PDBsum) 1dxo (PDBsum) see all
|
species |
[MACiE] |
| NADH dehydrogenase (ubiquinone) |
1.6.5.3 |
|
|
|
species |
[IntEnz] |
| 2-hydroxy-1,4-benzoquinone reductase |
1.6.5.7 |
|
|
|
|
[IntEnz] |
| NADPH dehydrogenase |
1.6.99.1 |
M0319 |
|
1z48 (PDBsum) 1bwk (PDBsum) see all
|
species |
[IntEnz] |
| NADH dehydrogenase |
1.6.99.3 |
|
|
1ozk (PDBsum) 3f8d (PDBsum) see all
|
species |
[KEGG] |
| NADPH dehydrogenase (quinone) |
1.6.99.6 |
|
|
|
|
[KEGG] |
| Nitrate reductase (NADH) |
1.7.1.1 |
|
1.10.1060.10 1.10.45.10 see all
|
1cne (PDBsum) 1cnf (PDBsum) see all
|
species |
[IntEnz] |
| Nitrate reductase (NAD(P)H) |
1.7.1.2 |
|
|
|
species |
[IntEnz] |
| Nitrate reductase (NADPH) |
1.7.1.3 |
|
|
2bii
(PDBsum) |
species |
[IntEnz] |
| Nitrite reductase (NAD(P)H) |
1.7.1.4 |
|
|
2jo6
(PDBsum) 2jza
(PDBsum) |
species |
[IntEnz] |
| Nitrite reductase (NO-forming) |
1.7.2.1 |
M0004 |
|
2ppf
(PDBsum) |
species |
[IntEnz] |
| Nitroalkane oxidase |
1.7.3.1 |
|
|
3bw4
(PDBsum) 3d9g
(PDBsum) |
|
[IntEnz] |
| 3-aci-nitropropanoate oxidase |
1.7.3.5 |
|
|
|
|
[IntEnz] |
| Hydroxylamine reductase |
1.7.99.1 |
|
|
1qks
(PDBsum) |
species |
[KEGG] |
| CoA-glutathione reductase |
1.8.1.10 |
|
|
|
|
[KEGG] |
| Trypanothione-disulfide reductase |
1.8.1.12 |
|
1.10.1060.10 1.10.45.10 see all
|
1aog (PDBsum) 1bzl (PDBsum) see all
|
species |
[IntEnz] |
| CoA-disulfide reductase |
1.8.1.14 |
|
|
1yqz (PDBsum) 3icr (PDBsum) see all
|
species |
[IntEnz] |
| Mycothione reductase |
1.8.1.15 |
|
|
|
|
[IntEnz] |
| Glutathione amide reductase |
1.8.1.16 |
|
|
|
|
[IntEnz] |
| Sulfite reductase (NADPH) |
1.8.1.2 |
|
1.10.1060.10 1.10.45.10 see all
|
1ddg (PDBsum) 1ddi (PDBsum) see all
|
species |
[IntEnz] |
| Dihydrolipoyl dehydrogenase |
1.8.1.4 |
|
1.10.1060.10 1.10.45.10 see all
|
1dxl (PDBsum) 1jeh (PDBsum) see all
|
species |
[IntEnz] |
| glutathione-disulfide reductase |
1.8.1.7 |
M0006 |
1.10.1060.10 1.10.45.10 see all
|
1bwc (PDBsum) 1dnc (PDBsum) see all
|
species |
[MACiE] |
| Thioredoxin-disulfide reductase |
1.8.1.9 |
|
1.10.1060.10 1.10.45.10 see all
|
1cl0 (PDBsum) 1f6m (PDBsum) see all
|
species |
[KEGG] |
| Glutathione oxidase |
1.8.3.3 |
|
|
|
|
[IntEnz] |
| Prenylcysteine oxidase |
1.8.3.5 |
|
|
|
species |
[IntEnz] |
| Adenylyl-sulfate reductase |
1.8.99.2 |
M0123 |
|
|
|
[MACiE] |
| Methionine synthase |
2.1.1.13 |
M0268 |
|
2o2k (PDBsum) 3bul (PDBsum) see all
|
species |
[KEGG] |
| Thymidylate synthase (FAD) |
2.1.1.148 |
|
1.10.1060.10 1.10.45.10 see all
|
1kq4 (PDBsum) 1o26 (PDBsum) see all
|
species |
[IntEnz] |
| tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase |
2.1.1.61 |
|
|
3awi (PDBsum) 3pvc (PDBsum) see all
|
|
[PDB] |
| Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase (FADH(2)-oxidizing) |
2.1.1.74 |
|
|
3g5q (PDBsum) 3g5r (PDBsum) see all
|
species |
[IntEnz] |
| Acetolactate synthase |
2.2.1.6 |
M0289 |
1.10.1060.10 1.10.45.10 see all
|
1jsc (PDBsum) 1n0h (PDBsum) see all
|
species |
[KEGG] |
| Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase |
2.3.1.168 |
|
|
3rnm (PDBsum) 2ii4 (PDBsum) see all
|
species |
[PDB] |
| CTP-dependent riboflavin kinase |
2.7.1.161 |
|
2.40.30.30 |
2vbv
(PDBsum) 3cta
(PDBsum) |
species |
[IntEnz] |
| Riboflavin phosphotransferase |
2.7.1.42 |
|
|
|
|
[IntEnz] |
| 2'-hydroxybiphenyl-2-sulfinate desulfinase |
3.13.1.3 |
|
|
2de4
(PDBsum) |
species |
[IntEnz] |
| FAD diphosphatase |
3.6.1.18 |
|
|
|
species |
[IntEnz] |
| Phosphopantothenoylcysteine decarboxylase |
4.1.1.36 |
|
|
1u80 (PDBsum) 1e20 (PDBsum) see all
|
species |
[IntEnz] |
| Tartronate-semialdehyde synthase |
4.1.1.47 |
M0298 |
|
2pan
(PDBsum) |
species |
[KEGG] |
| (6-4)DNA photolyase |
4.1.99.13 |
|
|
|
|
[IntEnz] |
| Deoxyribodipyrimidine photo-lyase |
4.1.99.3 |
M0183 |
1.10.1060.10 1.10.45.10 see all
|
1dnp (PDBsum) 1iqr (PDBsum) see all
|
species |
[MACiE] |
| 4-hydroxybutanoyl-CoA dehydratase |
4.2.1.120 |
|
|
|
|
[IntEnz] |
| Chorismate synthase |
4.2.3.5 |
|
|
2qhf (PDBsum) 1qxo (PDBsum) see all
|
species |
[IntEnz] |
| FAD-AMP lyase (cyclizing) |
4.6.1.15 |
|
|
|
species |
[IntEnz] |
| Isopentenyl-diphosphate Delta-isomerase |
5.3.3.2 |
M0190 |
|
2zrz (PDBsum) 3hyq (PDBsum) see all
|
species |
[IntEnz] |
The E.C. tree highlights the enzymes that use the cofactor on a tree of
all known E.C. numbers. Thus, it illustrates how frequently the cofactor is
used in enzyme reactions and where these reactions are located withing the
E.C. classification hierarchy.
In addition to the E.C. numbers extracted from primary literature, this graph
also incudes the E.C. numbers that have been automatically extracted from
several data resources.
The E.C. wheel is a pie chart-based representation of the enzyme
reactions this cofactor is involved in. The reactions are identified by E.C. number.
The colouring is performed by E.C. class. The figure has four levels of circles
which correspond to the four levels of the E.C. classification hierarchy. Partial
and full E.C. numbers are displayed where space suffices. Each area within the
outer two rings corresponds to one full E.C. serial number.
In addition to the E.C. numbers extracted from primary literature, this graph
also incudes the E.C. numbers that have been automatically extracted from
several data resources.
The flavin biosynthetic pathway is found in plants and microorganisms [7]. The flavin-dependent enzyme glycine oxidase is involved in thiamine biosynthesis.