Enzymes - Thiamine diphosphate

Thiamine diphosphate-using

Enzymes, which use Thiamine diphosphate as a cofactor

Further information

Recently, the enzyme 2-oxoacid oxidoreductase has been identified as a new thiamine-dependent enzyme [4].

Distribution of Thiamine diphosphate over enzyme reaction space (E.C.)

The E.C. tree highlights the enzymes that use the cofactor on a tree of all known E.C. numbers. Thus, it illustrates how frequently the cofactor is used in enzyme reactions and where these reactions are located withing the E.C. classification hierarchy.

In addition to the E.C. numbers extracted from primary literature, this graph also incudes the E.C. numbers that have been automatically extracted from several data resources.

E.C. tree

Profile of Thiamine diphosphate-containing reactions

The E.C. wheel is a pie chart-based representation of the enzyme reactions this cofactor is involved in. The reactions are identified by E.C. number. The colouring is performed by E.C. class. The figure has four levels of circles which correspond to the four levels of the E.C. classification hierarchy. Partial and full E.C. numbers are displayed where space suffices. Each area within the outer two rings corresponds to one full E.C. serial number.

In addition to the E.C. numbers extracted from primary literature, this graph also incudes the E.C. numbers that have been automatically extracted from several data resources.

E.C. wheel	Legend

Thiamine diphosphate-synthesising

Enzymes involved in Thiamine diphosphate biosynthesis

Further information

Thiamine diphosphate-binding

Enzymes binding to Thiamine diphosphate (mode unknown)

PROCOGNATE: proteins and cognate ligands

Protein domains that bind to this molecule

References

[1]	pubmed:17429582
[2]	pubmed:18183975
[3]	pubmed:20739284
[4]	pubmed:20956531
[5]	pubmed:17898894
[6]	pubmed:17898888