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LRRC8A:C conformation 1 (round) top focus

Source organisms:
Biochemical function: metal ion binding
Biological process: electron transport chain
Cellular component: periplasmic space

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF13855
Domain description: Leucine rich repeat
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A
  2. Volume-regulated anion channel subunit LRRC8C
The deposited structure of PDB entry 8drk contains 15 copies of Pfam domain PF13855 (Leucine rich repeat) in Soluble cytochrome b562. Showing 3 copies in chain A (this domain is out of the observed residue ranges!).
The deposited structure of PDB entry 8drk contains 2 copies of Pfam domain PF13855 (Leucine rich repeat) in Volume-regulated anion channel subunit LRRC8C. Showing 2 copies in chain F (this domain is out of the observed residue ranges!).

PF12534
Domain description: Pannexin-like TM region of LRRC8
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A
  2. Volume-regulated anion channel subunit LRRC8C
The deposited structure of PDB entry 8drk contains 5 copies of Pfam domain PF12534 (Pannexin-like TM region of LRRC8) in Soluble cytochrome b562. Showing 1 copy in chain A.
The deposited structure of PDB entry 8drk contains 1 copy of Pfam domain PF12534 (Pannexin-like TM region of LRRC8) in Volume-regulated anion channel subunit LRRC8C. Showing 1 copy in chain F.

PF07361
Domain description: Cytochrome b562
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A
The deposited structure of PDB entry 8drk contains 5 copies of Pfam domain PF07361 (Cytochrome b562) in Soluble cytochrome b562. Showing 1 copy in chain A (this domain is out of the observed residue ranges!).

InterPro InterPro annotations
IPR003591
Domain description: Leucine-rich repeat, typical subtype
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A
  2. Volume-regulated anion channel subunit LRRC8C
IPR001611
Domain description: Leucine-rich repeat
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A
  2. Volume-regulated anion channel subunit LRRC8C
IPR032675
Domain description: Leucine-rich repeat domain superfamily
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A
  2. Volume-regulated anion channel subunit LRRC8C
IPR021040
Domain description: LRRC8, pannexin-like TM region
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A
  2. Volume-regulated anion channel subunit LRRC8C
IPR009155
Domain description: Cytochrome b562
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A
IPR010980
Domain description: Cytochrome c/b562
Occurring in:
  1. Soluble cytochrome b562; Volume-regulated anion channel subunit LRRC8A

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