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Domain-swapped dimer of human Dishevelled2 DEP domain: monoclinic crystal form crystallised from monomeric fraction

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: intracellular signal transduction
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00610
Domain description: Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
  2. Segment polarity protein dishevelled homolog DVL-2
The deposited structure of PDB entry 5lnp contains 3 copies of Pfam domain PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)) in Segment polarity protein dishevelled homolog DVL-2. Showing 1 copy in chain C.
The deposited structure of PDB entry 5lnp contains 1 copy of Pfam domain PF00610 (Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)) in Segment polarity protein dishevelled homolog DVL-2. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR008339
Domain description: Dishevelled family
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
  2. Segment polarity protein dishevelled homolog DVL-2
IPR000591
Domain description: DEP domain
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
  2. Segment polarity protein dishevelled homolog DVL-2
IPR036390
Domain description: Winged helix DNA-binding domain superfamily
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
  2. Segment polarity protein dishevelled homolog DVL-2
IPR015506
Domain description: Dishevelled-related protein
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
  2. Segment polarity protein dishevelled homolog DVL-2
IPR036388
Domain description: Winged helix-like DNA-binding domain superfamily
Occurring in:
  1. Segment polarity protein dishevelled homolog DVL-2
  2. Segment polarity protein dishevelled homolog DVL-2

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