› 5ag9

X-ray diffraction
2.11Å resolution

Function and Biology Details

Reaction catalysed: 
Hydrolysis of proteins and small molecule substrates, with a preference for Arg in P1.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161161 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gingipain R2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 162 amino acids
Theoretical weight: 17.06 KDa
Source organism: Porphyromonas gingivalis W83
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P95493 (Residues: 577-736; Coverage: 23%)
Gene names: PG_0506, prtRII, rgp2, rgpB
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand SO4 5 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P21
Unit cell:
a: 51.57Å b: 61.81Å c: 54.05Å
α: 90° β: 116.79° γ: 90°
R-values:
R R work R free
0.195 0.192 0.254
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

The Type IX Secretion System (T9SS): Highlights and Recent Insights into Its Structure and Function.
Lasica et al. (2017)
6 more

2 mentions without citation

The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain.
de Diego et al. (2016)
1 more