EC 2.3.2.27: RING-type E3 ubiquitin transferase
Reaction catalysed:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine
Systematic name:
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine:[acceptor protein]-L-lysine ubiquitin transferase (isopeptide bond-forming; RING-type)
Alternative Name(s):
- RING E3 ligase
- Ubiquitin transferase RING E3
GO terms
Biochemical function:
Biological process:
Cellular component:
- not assigned
Sequence families
Protein families (Pfam)
InterPro annotations
Structure domains
CATH domains
3.30.505.10
Class:
Alpha Beta
Architecture:
2-Layer Sandwich
Topology:
SHC Adaptor Protein
Homology:
SH2 domain
Occurring in:
1.10.238.10
Class:
Mainly Alpha
Architecture:
Orthogonal Bundle
Topology:
Recoverin; domain 1
Homology:
EF-hand
Occurring in: