Assemblies
Assembly Name:
Succinate-semialdehyde dehydrogenase, mitochondrial
Multimeric state:
homo dodecamer
Accessible surface area:
195442.25 Å2
Buried surface area:
72713.58 Å2
Dissociation area:
174.91
Å2
Dissociation energy (ΔGdiss):
3.55
kcal/mol
Dissociation entropy (TΔSdiss):
19.14
kcal/mol
Symmetry number:
12
PDBe Complex ID:
PDB-CPX-156381
Assembly Name:
Succinate-semialdehyde dehydrogenase, mitochondrial
Multimeric state:
homo tetramer
Accessible surface area:
63389.75 Å2
Buried surface area:
26015.87 Å2
Dissociation area:
3,875.78
Å2
Dissociation energy (ΔGdiss):
58.17
kcal/mol
Dissociation entropy (TΔSdiss):
16.45
kcal/mol
Symmetry number:
4
PDBe Complex ID:
PDB-CPX-156383
Assembly Name:
Succinate-semialdehyde dehydrogenase, mitochondrial
Multimeric state:
homo dimer
Accessible surface area:
35714.71 Å2
Buried surface area:
8991.91 Å2
Dissociation area:
2,672.41
Å2
Dissociation energy (ΔGdiss):
29.75
kcal/mol
Dissociation entropy (TΔSdiss):
18.21
kcal/mol
Symmetry number:
2
PDBe Complex ID:
PDB-CPX-156382
Macromolecules
Chain: A
Length: 487 amino acids
Theoretical weight: 52.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Pfam: Aldehyde dehydrogenase family
InterPro:
Length: 487 amino acids
Theoretical weight: 52.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P51649 (Residues: 49-535; Coverage: 91%)
Pfam: Aldehyde dehydrogenase family
InterPro:
- Aldehyde/histidinol dehydrogenase
- Aldehyde dehydrogenase domain
- Aldehyde dehydrogenase, N-terminal
- Succinate semialdehyde dehydrogenase
- Aldehyde dehydrogenase, glutamic acid active site
- Aldehyde dehydrogenase, C-terminal
