Solution structure of the isolated histone H2A-H2B heterodimer
Source organism:
Homo sapiens
Biochemical function:
protein heterodimerization activity
Biological process: protein localization to CENP-A containing chromatin
Cellular component: CENP-A containing nucleosome
Biological process: protein localization to CENP-A containing chromatin
Cellular component: CENP-A containing nucleosome
Protein families (Pfam)![The deposited structure of PDB entry 2rvq contains 1 copy of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2A type 1-B/E. Showing 1 copy in chain A [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/2rvq_1_C_Pfam_PF00125_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2rvq</span> contains 1 copy of Pfam domain <span class='highlight'>PF00125 (Core histone H2A/H2B/H3/H4)</span> in <span class='highlight'>Histone H2A type 1-B/E</span>. Showing 1 copy in chain <span class='highlight'>A [auth C]</span>.")
![The deposited structure of PDB entry 2rvq contains 1 copy of Pfam domain PF00125 (Core histone H2A/H2B/H3/H4) in Histone H2B type 1-J. Showing 1 copy in chain B [auth D].](https://www.ebi.ac.uk/pdbe/static/entry/2rvq_2_D_Pfam_PF00125_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2rvq</span> contains 1 copy of Pfam domain <span class='highlight'>PF00125 (Core histone H2A/H2B/H3/H4)</span> in <span class='highlight'>Histone H2B type 1-J</span>. Showing 1 copy in chain <span class='highlight'>B [auth D]</span>.")
![The deposited structure of PDB entry 2rvq contains 1 copy of Pfam domain PF16211 (C-terminus of histone H2A) in Histone H2A type 1-B/E. Showing 1 copy in chain A [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/2rvq_1_C_Pfam_PF16211_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2rvq</span> contains 1 copy of Pfam domain <span class='highlight'>PF16211 (C-terminus of histone H2A)</span> in <span class='highlight'>Histone H2A type 1-B/E</span>. Showing 1 copy in chain <span class='highlight'>A [auth C]</span>.")
InterPro annotations
CATH domain![The deposited structure of PDB entry 2rvq contains 1 copy of CATH domain 1.10.20.10 (Histone, subunit A) in Histone H2A type 1-B/E. Showing 1 copy in chain A [auth C].](https://www.ebi.ac.uk/pdbe/static/entry/2rvq_1_C_CATH_1.10.20.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2rvq</span> contains 1 copy of CATH domain <span class='highlight'>1.10.20.10 (Histone, subunit A)</span> in <span class='highlight'>Histone H2A type 1-B/E</span>. Showing 1 copy in chain <span class='highlight'>A [auth C]</span>.")
![The deposited structure of PDB entry 2rvq contains 1 copy of CATH domain 1.10.20.10 (Histone, subunit A) in Histone H2B type 1-J. Showing 1 copy in chain B [auth D].](https://www.ebi.ac.uk/pdbe/static/entry/2rvq_2_D_CATH_1.10.20.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2rvq</span> contains 1 copy of CATH domain <span class='highlight'>1.10.20.10 (Histone, subunit A)</span> in <span class='highlight'>Histone H2B type 1-J</span>. Showing 1 copy in chain <span class='highlight'>B [auth D]</span>.")